목재가 선적된 선창에서 발생한 산소결핍에 의한 질식사

김동훈,김기권,장태정,김정란,이구,김수근,임현술 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

Oxygen deficiency has been frequent in a clouted space. Wood consumes oxygen and discharges carbon dioxide Instead of photosynthesis in closed space without light, so do some microorganisms on the surface. We experienced a case that a healthy Insect-proofer fell down and died of asphyxia on stair-board at 7 m below the hatch of the cargo-hold shipping wood Analysis of gases in cargo-hold revealed O2; 12.3%, CO; 105 ppm, CH4; 2.7%, and H2S; 1.9% at 1 m below the hatch, and then O2; 6.1%, CO; 220 ppm, CH4; 2.9%, and H2S, 2.3 ppm at 2.5 m below the hatch. Autopsy findings were unremarkable. We justiced the cause of death asphyxia due to oxygen deficiency. As seen in this case, the serious oxygen deficiency was accounted for oxygen consumption by wood and microorganisms.

여성노인의 저항운동 시 세트구성 방법의 차이가 Myokine에 미치는 영향

김명수 ( Kim¸ Myung-soo ),이승환 ( Lee¸ Sung-hwan ),민병남 ( Min¸ Byung-nam ),김재훈 ( Kim¸ Jae-hoon1 ),방현석 ( Bang¸ Hyun-seok ),김성희 ( Kim¸ Sung-hee ) 한국융합과학회(구 한국시큐리티융합경영학회) 2020 한국융합과학회지 Vol.9 No.4

연구목적: 본 연구는 여성노인을 대상으로 저항운동 시 사용되는 set구성 방법에 중 ascending set, descending set, drop set를 각각 적용시켜 Myokine의 변화를 알아보고자 하였다. 연구방법: 연구대상은 노인복지시설을 이용하고 있는 만 65-72세 사이의 여성노인 32명을 대상으로 ascending set, 8명, descending set 8명, drop set 8명, control group 8명으로 구분하였다. 자료처리는 반복측정에 의한 이원변량분석(two-way ANOVA with repeated measure)을 사용하였으며, 유의도는 .05로 하였다. 결론: 운동프로그램은 12주간 주 3회 실시하였으며, 신체구성과 IL-15, BDNF, VEGF, Irisin의 변화를 관찰하였다. 연구결과 신체구성의 체중, 체지방률, 제지방량 모두 유의한 차이가 없었다. IL-15와 BDNF는 운동 전·후의 비교결과 Descending set와 Drop set에서 운동 후 유의하게 증가하였고, 집단 간의 차이에서 Descending set와 Drop set 집단이 대조집단에 비하여 높게 나타났다. VEGF는 운동 전·후의 비교결과 Descending set와 Drop set 집단이 유의하게 증가하였으며, 집단 간의 차이에서 Descending set와 Drop set가 Ascending set와 control group 보다 높게 나타났다. Irisin은 집단 간 차이는 없었지만 Ascending, Descending, Drop set집단에서 운동 전에 비하여 운동 후 유의한 차이로 증가하였다.. Purpose: The purpose of this study is to identify the change of Myokine by applying ascending set, descending set, and drop set which are set composition used during elderly women’s resistance training. Method: 32 participants aged 65 to 72 who were users of welfare facilities for the aged were divided into 4 groups. They were ascending set group of 8, descending set group of 8, drop set group of 8, and control group of 8. The training program was conducted 3 times a week for 12 weeks and the change of body composition, IL-15(interleukin-15), BDNF(brain derived neurotrophic factor), VEGF(Vascular endothelial growth factor) and Irisin was observed. Two-way ANOVA with repeated measure was used for data processing. Result: The result of this study is as follows. Weight, %fat, and LBM(lean body mass) without fat showed no significant change. IL-15 and BDNF increased significantly after training in Descending set group(p<.05; p<.01)and Drop set group(p<.01; p<.05). VEGF significantly increased in descending set group(p<.01) and drop set group(p<.05). Among groups, VEGF was higher in descending set and drop set groups than ascending set and control groups. Irisin showed no difference between groups, but it showed significant increase after training in ascending(p<.05), descending(p<.05), and drop set groups(p<.05).

捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響

Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.

Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line

Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2

Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.

냉간압연된 Ni₃Al 박판재의 내산화 특성 개선을 위한 NiAl-Ti-Y 코팅의 증착

김수현,오명훈,Kishida, Kyosuke,Hirano, Toshiyuki,위당문 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.2

Since the intermetallic compound Ni_(3)Al has attractive high-temperature properties, Ni_(3)Al thin foils could be used as lightweight, high-temperature structural materials. The floating zone (FZ) method makes it possible to fabricate the thin foils with smooth and crack-free surface by cold rolling up to 96% without any intermediate annealing steps. For the practical application of Ni_(3)Al foils, the other properties such as oxidation resistance, wear resistance and friction resistance should be considered. The 3-NiAl, which is one of the important intermetallic compound in Ni-Al systems together with γ-Ni_(3)Al, have been used as coating materials of Ni-base superalloys because of its excellent oxidation resistance. In this study, the NiAl-based coating was intended to deposit on the Ni_(3)Al foils through RF magnetron sputtering. The binary Ni-50Al coating, however, was not able to form the stable α-Al_(2)O_(3) oxide. Moreover, the rapid Al diffusion between coating layer and substrate was occurred. On the contrary, it was found that the Ni-47Al-3Ti-0.1Y coating showed superior oxidation resistance due to stable α-Al_(2)O_(3) formation and good retardation of Al diffusion from coating layer.

RSC-300을 이용한 음성인식 시스템 구현

김수훈,안종영 부천대학 2002 論文集 Vol.23 No.-

본 논문에서는 Sensory사의 RSC-300을 이용하여 음성인식 시스템을 구현하였다. RSC-300은 음성 입력 시 이득조절이 가능한 프리앰프를 내장하고 있으며, 8비트 마이크로 컨트롤러를 탑재한 전용 칩으로 인식모델로 신경망을 이용하고 있다. 실험에서는 음성인식 시스템에서 화자의 음성을 인식하여 포트신호가 IR 컨트롤러를 구동시키고, 컨트롤러는 다시 IR 신호를 출력해 줌으로써 편리하게 제어할 수 있도록 하였으며, 메모리 용량을 고려하여 종속화자의 음성을 2회 학습시켜 사용하였다. 실험결과 80% 이상의 양호한 인식률을 보였으며, 장시간 사용시의 안정성 문제와 오동작에 대한 문제만 해결한다면 실생활에 적용이 가능할 것으로 사료된다. In this paper, we implement the speech recognition system using RSC-300, developed by Sensory Inc. RSC-300 is 8-bit microcontroller featuring 64K of internal ROM, on-chip A/D and D/A converters, 16 general purpose I/O lines, and an on-chip output amplifier. To implement speech recognition system, we used serial EEPROM(24C65) for data memory and Flash(29C20) ROM for program memory. In the experiment, we did the training process 2 times for training data. As a result of experiment, the system has good recognition ability and is expecting to be applied to daily life.

TQM과 6시그마 경영에 관한 고찰 : 서비스산업을 중심으로 Primarily on service industry

김동훈,고수복,장영준 한국품질경영학회 2002 품질경영학회지 Vol.30 No.3

In order to carry out TQM and 6 Sigma management, it is the key elements to make clear a goal and a mission. Above all, we can succeed in achieving a dramatic change and a great outcome only when we make clear the method, incentives, organization and plans under the clear objective. In order to secure the competitiveness against the external challenge, it is essential to keep the several crucial factors such as CEO's will, the systematic process to measure and manage, monitoring to satisfy customer's needs and an aggressive development of TQM activity to encourage the endeavour of the relentless enhancement, and also a positive effort is to be made for evaluating all quality culture like training experts internally by an outstanding training program under CEO's firm leadership. This study is carried out to understand that which features and factors of success can exist in a company culture if a company accepts a theoretical basis and concept, the general of TQM and 6 Sigma which are one of a management strategy, and carries out TQM and 6 Sigma for achieving improvement of quality and customer's satisfaction.

긴 관동맥병변에서 긴 스텐트삽입에 대한 임상경과 및 재협착율

김영학,박성욱,정상식,박훈기,이상곤,이일수,이철환,김재중,홍명기,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

설측 브라켓 부착을 위한 기준평면 설정에 관한 3차원 유한요소법적 연구

김선화,박수병,양훈철 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.1

교정치료 영역에서 성인들의 심미적인 요구도가 증가되면서 설측 교정치료는 여러 가지 단점에도 불구하고, 가장 심미적이라는 이유로 많은 주목을 받아왔지만 실제 치아이동을 결정지을 수 있는 브라켓을 부착하는 기준평면의 위치에 대해서는 거의 보고된 바가 없다. 이에 본 연구는 실제 브라켓이 부착되는 평면의 상하 평행이동이나 기울기 변화에 따라 치아이동 양상이 어떻게 변화되는지 알아보고, 바람직한 전치부 치체이동을 얻기 위해서 힘의 적용점을 어디에 두어야 하는지, 그리고 전치부에 어느 정도 모멘트를 부여해야 하는지 알아보고자 3차원 유한요소법을 이용하여 치아 변위 및 응력분포를 비교 분석하였다. 실험 결과 설측 브라켓 부착평면을 치은연쪽으로 평행이동 혹은 회전이동 시키고 견인하였을 경우, 절단연쪽으로 이동시켰을 때와 비교했을 때 비조절성 설측 경사이동이 감소하기는 하였으나 상하악 전치부 치아들의 설측경사 양상은 지속되었으며, 이러한 양상은 견치 브라켓의 hook 길이를 증가시켜도 계속 나타났다. 이와는 달리 설측 중심평면에 브라켓을 부착하고 각 치아별로 모멘트를 부여하였을 경우 설측 방향으로 개개 치아들의 치체이동이 발생하여 설측 교정치료 시 효과적인 전치부 치아의 후방견인이 가능함을 알 수 있었다. This study was performed to investigate the location of the ideal bracket positioning plane in lingual orthodontics using the three-dimensional finite element method. Displacement of the anterior teeth were evaluated according to the vertical and the angular movements of the bracket positioning plane. To achieve the ideal movement of anterior teeth in the lingual central plane, the location of the force application point and the amount of the moment applied to the four incisors were evaluated. As the bracket positioning plane was moved parallel toward the incisal edge, uncontrolled tipping and extrusion of the maxillary and the mandibular incisors were increased. But lingual tipping of the crown was decreased in the maxillary and the mandibular canines. As the bracket positioning plane was inclined toward the incisal edge, lingual tipping was increased in the 6 anterior teeth and extrusion of incisors and intrusion of the canine was also increased. As the retraction hook of the canine bracket was elongated, lingual tipping and extrusion of the central incisor and mesial movement and extrusion of the lateral incisor were increased. In the canine, mesial and labial movements of the crown were increased. When the moment was applied to the 4 incisors of the maxillary and the mandibular arch in the lingual central plane, 280 gf-mm in the maxillary central incisor, 500 gf-mm in the maxillary lateral incisor, 170 gf-mm in the mandibular central incisor and 370 gf-mm in the mandibular lateral incisor produced bodily movement of the individual tooth.

주상정 결정립의 NiAl 마르텐사이트 제조에 의한 NiAl/Ni_3Al 일방향응고 합금의 미세조직 제어

김수현,오명훈,위당문 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.3

In the our previous studies about the two-phase NiAl/Ni_3Al alloys, the various microstrucutures of polycrystalline NiAl/Ni_3Al alloys could be obtained by the M_s temperature control of NiAl-martensite including titanium, and the mechanical properties were considerably dependent on their microstructures. In this study, the grain boundaries were tried to align by directional solidification to suppress the inter granular fracture at room temperature or grain boundary sliding at high temperature. To effectively maintain the grain boundary alignment in the course of the heat-treatment of a DS ingot, suppressing recrystallization during solutionizing treatment, which is the preceding process of martensitic transformation of a DS alloy, is very important. Based on the orientation relationship between parent β-NiAl(the B2 structure)and product β'-martensite(the L1_0 structure), the optimum heat-treatment conditions for DS ingot were determined through XRD observation. Consequently, the columnar grained NiAl/Ni_3Al alloys could be achieved for the only Ti-added ternary ingot contrary to the recrystallized binary ingot. And, the columnar grained alloys including Ti could show higher yield strength at high temperature than the usual polycrystalline alloys.