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김동훈,김기권,장태정,김정란,이구,김수근,임현술 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1
Oxygen deficiency has been frequent in a clouted space. Wood consumes oxygen and discharges carbon dioxide Instead of photosynthesis in closed space without light, so do some microorganisms on the surface. We experienced a case that a healthy Insect-proofer fell down and died of asphyxia on stair-board at 7 m below the hatch of the cargo-hold shipping wood Analysis of gases in cargo-hold revealed O2; 12.3%, CO; 105 ppm, CH4; 2.7%, and H2S; 1.9% at 1 m below the hatch, and then O2; 6.1%, CO; 220 ppm, CH4; 2.9%, and H2S, 2.3 ppm at 2.5 m below the hatch. Autopsy findings were unremarkable. We justiced the cause of death asphyxia due to oxygen deficiency. As seen in this case, the serious oxygen deficiency was accounted for oxygen consumption by wood and microorganisms.
여성노인의 저항운동 시 세트구성 방법의 차이가 Myokine에 미치는 영향
김명수 ( Kim¸ Myung-soo ),이승환 ( Lee¸ Sung-hwan ),민병남 ( Min¸ Byung-nam ),김재훈 ( Kim¸ Jae-hoon1 ),방현석 ( Bang¸ Hyun-seok ),김성희 ( Kim¸ Sung-hee ) 한국융합과학회(구 한국시큐리티융합경영학회) 2020 한국융합과학회지 Vol.9 No.4
연구목적: 본 연구는 여성노인을 대상으로 저항운동 시 사용되는 set구성 방법에 중 ascending set, descending set, drop set를 각각 적용시켜 Myokine의 변화를 알아보고자 하였다. 연구방법: 연구대상은 노인복지시설을 이용하고 있는 만 65-72세 사이의 여성노인 32명을 대상으로 ascending set, 8명, descending set 8명, drop set 8명, control group 8명으로 구분하였다. 자료처리는 반복측정에 의한 이원변량분석(two-way ANOVA with repeated measure)을 사용하였으며, 유의도는 .05로 하였다. 결론: 운동프로그램은 12주간 주 3회 실시하였으며, 신체구성과 IL-15, BDNF, VEGF, Irisin의 변화를 관찰하였다. 연구결과 신체구성의 체중, 체지방률, 제지방량 모두 유의한 차이가 없었다. IL-15와 BDNF는 운동 전·후의 비교결과 Descending set와 Drop set에서 운동 후 유의하게 증가하였고, 집단 간의 차이에서 Descending set와 Drop set 집단이 대조집단에 비하여 높게 나타났다. VEGF는 운동 전·후의 비교결과 Descending set와 Drop set 집단이 유의하게 증가하였으며, 집단 간의 차이에서 Descending set와 Drop set가 Ascending set와 control group 보다 높게 나타났다. Irisin은 집단 간 차이는 없었지만 Ascending, Descending, Drop set집단에서 운동 전에 비하여 운동 후 유의한 차이로 증가하였다.. Purpose: The purpose of this study is to identify the change of Myokine by applying ascending set, descending set, and drop set which are set composition used during elderly women’s resistance training. Method: 32 participants aged 65 to 72 who were users of welfare facilities for the aged were divided into 4 groups. They were ascending set group of 8, descending set group of 8, drop set group of 8, and control group of 8. The training program was conducted 3 times a week for 12 weeks and the change of body composition, IL-15(interleukin-15), BDNF(brain derived neurotrophic factor), VEGF(Vascular endothelial growth factor) and Irisin was observed. Two-way ANOVA with repeated measure was used for data processing. Result: The result of this study is as follows. Weight, %fat, and LBM(lean body mass) without fat showed no significant change. IL-15 and BDNF increased significantly after training in Descending set group(p<.05; p<.01)and Drop set group(p<.01; p<.05). VEGF significantly increased in descending set group(p<.01) and drop set group(p<.05). Among groups, VEGF was higher in descending set and drop set groups than ascending set and control groups. Irisin showed no difference between groups, but it showed significant increase after training in ascending(p<.05), descending(p<.05), and drop set groups(p<.05).
捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響
Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1
Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.
Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line
Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.
소아에서 Fogarty 카테터를 이용한 일측폐 환기 마취 경험
유수봉,강효석,임지훈,김두식,류시정 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3
Thoracic surgery may be greatly facilitated by causing selective atelectasis of the lung being operated on (one-lung ventilation anesthesia). But the tube used for one-lung ventilation is greater outer diameter than conventional endotracheal tube when compare to each other with same inner diameter, so in some young children it is impossible to one-lung ventilation using double lumen tube or bronchial blocker tube because of narrow vocal cord. We performed one lung ventilation anesthesia using conventional endotracheal tube and Fogarty catheter as a bronchial blocker in 11-year old women who received lung biopsy surgery and left lower lobectomy.
주상정 결정립의 NiAl 마르텐사이트 제조에 의한 NiAl/Ni_3Al 일방향응고 합금의 미세조직 제어
김수현,오명훈,위당문 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.3
In the our previous studies about the two-phase NiAl/Ni_3Al alloys, the various microstrucutures of polycrystalline NiAl/Ni_3Al alloys could be obtained by the M_s temperature control of NiAl-martensite including titanium, and the mechanical properties were considerably dependent on their microstructures. In this study, the grain boundaries were tried to align by directional solidification to suppress the inter granular fracture at room temperature or grain boundary sliding at high temperature. To effectively maintain the grain boundary alignment in the course of the heat-treatment of a DS ingot, suppressing recrystallization during solutionizing treatment, which is the preceding process of martensitic transformation of a DS alloy, is very important. Based on the orientation relationship between parent β-NiAl(the B2 structure)and product β'-martensite(the L1_0 structure), the optimum heat-treatment conditions for DS ingot were determined through XRD observation. Consequently, the columnar grained NiAl/Ni_3Al alloys could be achieved for the only Ti-added ternary ingot contrary to the recrystallized binary ingot. And, the columnar grained alloys including Ti could show higher yield strength at high temperature than the usual polycrystalline alloys.
김주성,김상범,김수훈,허강인 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1
In this paper, we perform the recognition test for Korean 100 monosyllabes using RPNN(recurrent prediction neural networks). The RPNN is trained to nonlinear predictor, accoding to time variation of speech pattern, is not use time sequential algorithm. In recognition experiment we got the recognition rate 69.0%, 72.30% and 71.20% using RTRL(real-time recurrent learning) training algorithm when the predition order is 2, 3 and 4.
김수성,조재훈,이학승,박현영,장혁,김요식,조광호 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1
항응고제 치료의 주된 합병증은 출혈로서 주로 뇌실질과 복강 내에 발생하며 사지 근육에 발생하는 근육내 혈종은 매우 드문 것으로 알려져 있다. 이러한 항응고제 치료 후 발생하는 자발성 근육내 혈종은 발생빈도가 드물 뿐 아니라, 심부정맥혈전증과 그 증상이 유사하여 감별하기가 쉽지 않다. 저자들은 항응고제 치료 후 운동 마비가 발생한 사지 근육에서 자발성 근육내 혈종이 발생한 증례를 경험하여 이를 보고한다. Spontaneous intramuscular hematoma(SIH) is an uncommon but serious bleeding complication of anticoagulation therapy that has received little attention. We present a patient of spontaneous muscular hematoma during anticoagulation therapy for acute stroke management. A-74-year old man was admitted with sudden onset of dysarthria and left hemiparesis. Brain MRI and MRA showed acute cerebral infarction along right middle cerebral artery territory and severe stenosis of right proximal cervical internal carotid artery. During intravenous heparin treatment, he complained acute pain and swelling on left leg. Muscular CT showed enhancing focal soft tissue mass on left gastrocnemius muscle and ultrasonography demonstrated multiple hematomas on left gastrocnemius muscle. Treatment of heparin was stopped immediately. After conservative management for hematomas, symptoms were subsided.
김용수,태순호,우훈하 서울産業大學校 1994 논문집 Vol.40 No.1
The primary intent of this study to introduce basic mathematical fire modeling. The approach is through the development of a simple mathematical model that will provide on engineering approximation of the time-varying condition created by a fire in an enclosure that may be subject to hot-layer venting. The hot-layer, as it is commonly referred to in fire modeling, is the collection of hot gases generated by a fire that forms below the ceiling due to its buoyancy over the ambient temperature air in the compartment. In the model, venting due to buoyancy forces is considered, with vent flows associated with momentum and forced ventilation are not. Also, venting through opening in vertical planes(walls) is considered, and openings in horizontal planes(floor and celling)are not. Early work revealed two general approaches for a solution. First, there was the opportunity to simplity an existing, but complex model, such as the Harvard Code, FIRST, or FAST, or FAST. A second option would be to take existing simple model such as ASET-B, and upgrade it is meet the requirements of model and documentation sought. However, during the modification of ASET-B, it became apparent that it could be simplified move. As a result, the model developed here is not simply a modification of ASET-B, but a completely new model. however, the ASET-B model did have an important role in the development of the there model. Initial motivation for the simplicity and structure of the model was so that it could be used as a tool in the investigation and reconstruction of fires. Modified FIRM(Fire Investigation and Reconstruction model)is certainly not limited to those uses.
냉간압연된 Ni₃Al 박판재의 내산화 특성 개선을 위한 NiAl-Ti-Y 코팅의 증착
김수현,오명훈,Kishida, Kyosuke,Hirano, Toshiyuki,위당문 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.2
Since the intermetallic compound Ni_(3)Al has attractive high-temperature properties, Ni_(3)Al thin foils could be used as lightweight, high-temperature structural materials. The floating zone (FZ) method makes it possible to fabricate the thin foils with smooth and crack-free surface by cold rolling up to 96% without any intermediate annealing steps. For the practical application of Ni_(3)Al foils, the other properties such as oxidation resistance, wear resistance and friction resistance should be considered. The 3-NiAl, which is one of the important intermetallic compound in Ni-Al systems together with γ-Ni_(3)Al, have been used as coating materials of Ni-base superalloys because of its excellent oxidation resistance. In this study, the NiAl-based coating was intended to deposit on the Ni_(3)Al foils through RF magnetron sputtering. The binary Ni-50Al coating, however, was not able to form the stable α-Al_(2)O_(3) oxide. Moreover, the rapid Al diffusion between coating layer and substrate was occurred. On the contrary, it was found that the Ni-47Al-3Ti-0.1Y coating showed superior oxidation resistance due to stable α-Al_(2)O_(3) formation and good retardation of Al diffusion from coating layer.