http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
강모단 하방에 용수철이 부착된 칫솔의 치태 제거 효과에 관한 임상적 연구
조성훈,양규호,오종석 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1
Oral examinations were conducted before the experiment started. The students were given common toothbrushes (control group) or spring-attached toothbrushes (experimental group) and instructed to brush their teeth by scrubbing method. Measurement of plaque index and count of salivary bacteria were done at 0, 1, 3, and 5 weeks. 1. Mean plaque index was significantly reduced at week 1 compared with at week 0 in both groups. (P<0.05) 2. Mean plaque index was significantly reduced at week 3 compared with at week 1 in the experimental group. (P<0.05) 3. Mean plaque index was significantly reduced at week 5 compared with at week 3 in the experimental group. (P<0.05) 4. There were no significant differences of mean plaque index among week 1, week 3, and week 5 in control group. (P>0.05) 5. The number of salivary bacteria was slightly reduced during the experiment, however there was no statistical significance. (P>0.05) To reduce the plaque effectively, the use of spring-attached toothbrush should be recommended, and adequeate instruction for children is needed.
구민선,김영수,오훈일,김종규 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4
순창의 찹쌀고추장, 사천 밀고추장, 보은 보리고추장으로부터 분리된 숙성 시기별로 400여개 균주를 채취하여 고추장 발효용 배지에 각 균을 접종하여 30℃에서 75일간 배양 후 맛과 향에 대해 3차에 걸쳐 훈련된 관능요원들이 관능검사를 실시하고, 동시에 preparative GC를 이용하여 sniffing test를 하여 최종적으로 전통 고추장의 향과 맛에 가장 유사한 풍미를 생산하는 세균 1종과 효모 1종을 각각 선발하였다. 동정을 하기 위하여 형태학적, 생리학적 실험을 한 결과 최종 선발된 세균은 Bacillus licheniformis로, 효모는 Saccaromyces dairensis로 동정되어졌다. 특히 세균은 혐기상태에서도 성장이 가능했으며, 고추장의 주원료인 전분질 분해능이 우수했다. Microorganisms were collected to isolate the microbes producing Kochujang flavor from 3 kinds of traditional Kochujang. The strain B7 and Y20 which scored the highest sensory evaluation value among 400 microorganisms were finally selected. Also, they showed the most similar flavor pattern to the traditional kochujang's by comparison of GC chromatogram after sniffing test. As the result of the result of the morphological and physiological experiments, the bacterial strain B7 could be identified Bacillus licheniformis and the yeast strain Y20 Saccaromyces dairensis. Especially, the bacterial strain B7 could grow in anaerobic condition and was able to hydrolysis the starch that was the major component in Kochujang.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구
노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.
Oh, Tae Hoon,Oh, Se-Kyu,Kim, Hosoo,Lee, Kyungmoo,Lee, Jong Min American Chemical Society 2017 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.56 No.25
<P>To obtain aromatic compounds from a crude mixture such as reformate or pyrolysis gasoline, three different processes are simulated with the realistic composition of reformate and product specification. Simulations were performed by Aspen Plus supported with COSMO-RS method to predict the physical and thermodynamic properties of ionic liquid. Furthermore, utility analysis and economic evaluation are presented. Conventionally, aromatic compounds are extracted from a crude mixture either by extraction or by extractive distillation using a solvent such as sulfolane and separated by a series of distillation columns. In this study, the sulfolane-based commercial process is first introduced, and two novel processes that use 4-methyl-N-butylpyridinium tetrafluoroborate ionic liquid as solvent are proposed. The second process shows that energy consumption has successfully decreased, but the high price of ionic liquid offset the cost advantage. The third process is therefore proposed to reduce the amount of ionic liquid using two extractions. A similar level of energy saving is achieved with reduced costs.</P>
Oh, Hoon Kyu,Choi, Youn Seok,Yang, Yeong-In,Kim, Ji-Hyun,Leung, Peter C K,Choi, Jung-Hye Published for the European Society for Human Repro 2013 Molecular human reproduction Vol.19 No.3
<P>Leptin acts as a potential growth stimulator in several normal and neoplastic cells. Recent studies have shown the presence of increased levels of leptin in the peritoneal fluid of patients with endometriosis, implicating leptin in the pathogenesis of endometriosis. However, the specific function of leptin in the induction of mitogenesis in endometriosis is not known. This study investigated the expression of the leptin receptor (ObR) in endometrioma tissues and immortalized endometriotic cells, and the effect of leptin on cell growth. ObR expression was higher in endometriomas than in the normal endometrium, and it was detected in 74% of epithelial and 30% of stromal endometrioma tissues. In addition, human endometriotic epithelial cells (11Z and 12Z) showed a high level of ObR when compared with endometrial cells and endometriotic stromal cells (22B). Furthermore, leptin treatment stimulated the growth of 11Z and 12Z cells, but not that of 22B cells. Knockdown of the ObR in 11Z and 12Z cells impaired the ability of leptin to induce cell growth. Leptin induced the activation of Janus Kinases 2 (JAK2), signal transducers and activators of transcription 3 (STAT3) and extracellular signal-regulated kinase (ERK) in endometriotic epithelial cells. Moreover, pretreatment with the JAK2/STAT3 inhibitor AG490 and the ERK inhibitor PD98059 significantly inhibited leptin-induced cell growth. The present results show that the ObR is induced in endometriosis, and that leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways.</P>
Oh, Jang-Hoon,Kim, Hyug-Gi,Woo, Dong-Cheol,Jeong, Ha-Kyu,Lee, Soo Yeol,Jahng, Geon-Ho 한국물리학회 2017 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol. No.
<P>The physical and technical development of chemical-exchange-saturation-transfer (CEST) magnetic resonance imaging (MRI) using clinical 3 T MRI was explored with the goal of mapping asparagine (Asn), gamma-aminobutyric acid (GABA), glutamate (Glu), glycine (Gly), and myoinositol (MI), which exist in the brain. Phantoms with nine different conditions at concentrations of 10, 30, and 50 mM and pH values of 5.6, 6.2, and 7.4 were prepared for the five target molecules to evaluate the dependence of the CEST effect in the concentration, the pH, and the amplitude of the applied radiofrequency field B-1. CEST images in the offset frequency range of +/- 6 parts per million (ppm) were acquired using a pulsed radio-frequency saturation scheme with a clinical 3 T MRI system. A voxel-based main magnetic field B-0 inhomogeneity correction, where B-0 is the center frequency offset at zero ppm, was performed by using the spline interpolation method to fit the full Z-spectrum to estimate the center frequency. A voxel-based CEST asymmetry map was calculated to evaluate amide (-NH), amine (-NH2), and hydroxyl (-OH) groups for the five target molecules. The CEST effect for Glu, GABA, and Gly clearly increased with increasing concentrations. The CEST effect for MI was minimal, with no noticeable differences at different concentrations. The CEST effect for Glu and Gly increased with increasing acidity. The highest CEST asymmetry for GABA was observed at pH 6.2. The CEST effect for Glu, GABA, and Gly increased with increasing B1 amplitude. For all target molecules, the CEST effect for the human 3 T MRI system increased with increasing concentration and B1 amplitude, but varied with pH, depending on the characteristics of the molecules. The CEST effect for MI may be not suitable with clinical MRI systems. These results show that CEST imaging in the brain with the amine protons by using 3 T MRI is possible for several neuronal diseases.</P>
Sung Hoon Kim,Min Kyu Kang,Ji Woon Yea,Sung Kyu Kim,Ji Hoon Choi,Se An Oh 대한방사선종양학회 2012 Radiation Oncology Journal Vol.30 No.3
Purpose: This treatment planning study was undertaken to evaluate the impact of beam angle configuration of intensitymodulated radiotherapy (IMRT) on the dose of the normal liver in hepatocellular carcinoma (HCC). Materials and Methods: The computed tomography datasets of 25 patients treated with IMRT for HCC were selected. Two IMRT plans using five beams were made in each patient; beams with equidistance of 72˚ (Plan I), and beams with a 30˚ angle of separation entering the body near the tumor (Plan II). Both plans were generated using the same constraints in each patient. Conformity index (CI), homogeneity index (HI), gamma index, mean dose of the normal liver (Dmean_NL), Dmean_NL difference between the two plans, and percentage normal liver volumes receiving at least 10, 20, and 30 Gy (V10, V20, and V30) were evaluated and compared. Results: Dmean_NL, V10, and V20 were significantly better for Plan II. The Dmean_NL was significantly lower for peripheral (p =0.001) and central tumors (p = 0.034). Dmean_NL differences between the two plans increased in proportion to gross tumor volume to normal liver volume ratios (p = 0.002). CI, HI, and gamma indices were not significantly different for the two plans. Conclusion: The IMRT plan based on beams with narrow separations reduced the irradiated dose of the normal liver, which would allow radiation dose escalation for HCC.