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개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases
최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2
Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.
최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2
Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.
이정희,서홍주,이석기 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3
Background: Diaphragmatic rupture may occur from blunt or penetrating thoracoabdominal trauma, which may be undiagnosed initially in the acute trauma, work-up and may remain unrecognized. Delayed traumatic diaphragmatic rupture is reported with increasing frequency and is associated with high morbidity and mortality. The purpose of this study was to present our experience and found out early diagnostic method, clinical presentation and management. Matehals and Methods: From March 1998 to February 2004, the 6 patients of delayed diaphragmatic rupture in our hospital were operated. We reviewed the diagnostic interval, symptom, diagnostic method, operative method and complication. Resutt: They were 3 men and 3 women. Mean age was 56.8:t15.8 years(range 29-69). Most common symptom was dyspnea. Delayed diaphragmatic rupture was right-sided in 4 patients, left-sided in 2. The average operative interval of delayed diaphragmatic rupture was 18.8 months(range 5-48). The diagnosis was chest x-ray and thoracic CT. Operative approach were only thorax in 4 patients and both thorax and abdomen in 2. Postoperative complication were observed in 4 patients, and the overall mortality was none. Conclusion: The delayed case of traumatic diaphragmatic rupture tends to be overlooked without suspicion, In all patients with thoracoabdominal blunt injury a rupture of the diaphragm must be suspected. With a high suspicion, a thorough physical examination and diagnostic method is recommended in order to avoid early or late complications.
대간간학회지 제6차 춘계학술대회 초록집 : 포스터 발표 ; 만성 B형 간질환에서 라미부딘 치료
서연석 ( Seo Yeon Seog ),김윤홍 ( Kim Yun Hong ),공휘 ( Gong Hwi ),김지훈 ( Kim Ji Hun ),박상훈 ( Park Sang Hun ),연종은 ( Yeon Jong Eun ),변관수 ( Byeon Gwan Su ),이창홍 ( Lee Chang Hong ),정문기 ( Jeong Mun Gi ),김성권 ( Kim Se 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.1(S)
혈중 Lipoprotein ( a ) 의 농도가 인체내 혈전 생성 및 용해 인자에 미치는 영향에 관한 연구
서홍석(Hong Seog Seo),오동주(Dong Joo Oh),이은미(Eun Mi Lee),한승환(Sung Whan Han),박희남(Hui Nam Pak),임도선(Do Sun Lim),박창규(Chang Kyu Park),김영훈(Young Hoon Kim),심완주(Wan Joo Shim),노영무(Young Moo Ro),권정아(Jung Ah Kwon),이갑 대한내과학회 1996 대한내과학회지 Vol.51 No.1
N/A Objectives: Recently, lipoprotein (a) is known as an independent genetic risk factor for cardiovascular disease. Lipoprotein (a) contains a unique structure, apolipoprotein(a), that shares a partial homology with plasminogen without haboring enzymatic activity. Several in vitro studies reported that lipoprotein(a) competes with plgsminogen for their receptors showing inhibited thrombolysis and promoted thrombosis. We investigated whether evalvuated that lipoprotein(a) has same properties in vivo by determining the homeostatic relation between lipoprotein(a) concentration and several parameters of thrombosis and thrombolysis, and whether parameters of thrombosis and thrombolysis are different in atherosclerotic vascular diseases. Methods: Lipoprotein(a), fibrinogen, plasminogen, FDP-d, antithrombin-III, prothrombin time, activated partial thromboplastin time, tissue-type plasminogen activator, alpha-2 antiplasmin, plaminogen activator inhibitor-l, platelet counts, and other lipid profiles were measured and were compared each others by venous samles in 239 cases with atherosclerotic vascular disease which consisted of 146 cases of coronary heart disease, 39 cases of non-hemorrhagic cerebral infarction, and 10 cases of arteriosclerosis obliterans and in 185 cases without atherosclerotic vascular disease., Results: There was neither significant homeostatic relationship between lipoprotein(a) levels and paramets d thrombolysis, nor between lipids levels and parameters of thrombosis and thrombolysis. Serum lipoprotein(a) levels were higher in patients with myocardial infarction than in those with non- atherosclerotic vascular disease(30.0±28.2mg vs 23.8±21.4mg/dl). Among the thrombogenic and thrombolytic parameters, only tPA and FDP-d were significantly elevated in patients with atherosclerotic vascular disease. Conclusion: The findings that lipoprotien(a) was not correlated with thrombogenic and thrombolytic profiles in vivo suggests that lipoprotein(a) is not related to thrombogenicity in Korean people, al- though lipoprotein(a) is a independent genetic risk factor for carodiovascular disease.
제5차 대한간학회 춘계학술대회 초록집 : 포스터 전시 순서 ; 간에 단일결절로 나타난 특발성 과호산구증가 증후군 치험 1예
서연석 ( Seo Yeon Seog ),김경오 ( Kim Gyeong O ),손수민 ( Son Su Min ),김윤홍 ( Kim Yun Hong ),박상훈 ( Park Sang Hun ),권오상 ( Kwon O Sang ),연종은 ( Yeon Jong Eun ),변관수 ( Byeon Gwan Su ),이창홍 ( Lee Chang Hong ) 대한간학회 1999 Clinical and Molecular Hepatology(대한간학회지) Vol.5 No.1(S)