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In-Jae Park,Se-Yeoun Cha,Min Kang,Yang-Seop So,Hiw-Gon Go,Young-Ho Son,Sung-Phil Mun,Kyung-Seon Ryu,Hyung-Kwan Jang 韓國家禽學會 2010 韓國家禽學會誌 Vol.37 No.4
We evaluated the immunomodulatory effects of proanthocyanidin-rich extract (PAE) from Pinus radiata bark in broiler. Proliferation of peripheral blood mononuclear cells and thymocytes was significantly enhanced in 2.5, 5, 10 ㎎/㎏ PAE-treated broiler chickens. Proliferation of splenocytes was significantly enhanced in 1.25, 2.5, 5, 10 ㎎/㎏ PAE-treated broiler chickens. These effects were markedly enhanced by the presence of LPS, which acts on B cells responsible for humoral immunity, and Con A, which acts directly on T cells involved in cell mediated immunity. PAE significantly promoted the expression of interleukin-18 and interleukin-1β. Thus, PAE from P. radiata possesses immunomodulatory effects in broiler chickens.
Park, In-Jae,Cha, Se-Yeoun,Kang, Min,So, Yang-Seop,Go, Hiw-Gon,Son, Young-Ho,Mun, Sung-Phil,Ryu, Kyung-Seon,Jang, Hyung-Kwan The Korean Society of Poultry Science 2010 韓國家禽學會誌 Vol.37 No.4
We evaluated the immunomodulatory effects of proanthocyanidin-rich extract (PAE) from Pinus radiata bark in broiler. Proliferation of peripheral blood mononuclear cells and thymocytes was significantly enhanced in 2.5, 5, 10 mg/kg PAE-treated broiler chickens. Proliferation of splenocytes was significantly enhanced in 1.25, 2.5, 5, 10 mg/kg PAE-treated broiler chickens. These effects were markedly enhanced by the presence of LPS, which acts on B cells responsible for humoral immunity, and Con A, which acts directly on T cells involved in cell mediated immunity. PAE significantly promoted the expression of interleukin-18 and interleukin-$1\beta$. Thus, PAE from P. radiata possesses immunomodulatory effects in broiler chickens.