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完全高密度化된 液相燒結試片의 液相吸入現象에 미치는 固相粒子크기의 영향
權五鍾,李周翰,姜大甲 慶北大學校 1984 論文集 Vol.38 No.-
The effect of Co grain size on the liquid absorption of completely densified Co-Cu compacts by liquid phase sintering is investigated. The compacts of which composition is 80 wt. % Co-20 wt. % Cu, were prepared by ordinary powder metallurgy techniques. To eliminate pores completely and to vary the average size of solid Co grains, the compacts were sintered at 1250℃ for from 1.5-up to 32 hours. A small pellet of 11 wt. % Co-89 wt. % Cu was put into a small hole drilled at the specimen surface. Then the assembly was annealed at the same temperature for from one up to 17 hours. The pellet melted immediately and formed a liquid pool. The presintered body absorbed liquid from the pool. The smaller the solid grain size, the more liquid was absorbed. The amount of the absorbed liquid also increased with the increase of annealing time. The driving force of liquid absorption is expected to be the tendency of anhedral solid grains to restore spherical shape, of which interfacial free energy is lower.
權五鍾,李周翰 경북대학교 공과대학 1983 工大硏究誌 Vol.12 No.-
A simple geometrical model for the interaction between second phase inclusions and grain boundary is suggested. This model indicates that the attracting force of second phase inclusions increases with the decrease in the dihedral angle of inclusions formed at grain boundary. The "joining angle" of grain boundary at which the attracting force shows the maximum value increases with the decrease in dihedral angle, too. Consequently, the maximum average grain size during grain growth is expected to be smaller with smaller dihedral angle.
( Dan Bi Lee ),( Young Hwa Chung ),( Sae Hwan Lee ),( Yoon Seon Lee ),( Don Lee ),( Jeong Eun Hwang ),( Kang Mo Kim ),( Young Suk Lim ),( Han Chu Lee ),( Eun Sil Yu ),( Young Sang Lee ),( Dong Jin Suh 대한소화기학회 2007 Gut and Liver Vol.1 No.1
Background/Aims: The authors examined whether the response to interferon (IFN) therapy can affect the development of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients. Methods: Out of 353 biopsy-proven CHB patients, 229 (65%) were treated with IFN-α for 6 to 12 months. They were followed for a median period of 75 months (range, 6-120). In patients treated with IFN, biochemical and virologic responses were evaluated at the end of treatment (EOT). The cumulative incidence rates of HCC were calculated and analyzed in relation to baseline characteristics as well as biochemical and virologic responses to IFN therapy. Results: The overall cumulative incidence of HCC was 0%, 0.8%, 3.7% and 5.5% at 3, 5, 7 and 8 years, respectively. Age, serum AFP levels and the stage of fibrosis were significantly associated with the occurrence of HCC. As a whole, IFN therapy did not affect the occurrence of HCC. Among the patients treated with IFN, biochemical responders had low HCC incidence rates compared with non-responders (p=0.018). However, the HCC incidence rates of virologic responders were not different from non-responders (p=0.203). Conclusions: Biochemical rather than virologic response to IFN therapy may be more closely associated with decrease of HCC incidence in CHB patients. (Gut and Liver 2007;1:49-55)
A new method for monitoring an OLED panel for lighting by sensing the wave-guided light
Han, Jun-Han,Moon, Jaehyun,Shin, Jin-Wook,Joo, Chul Woong,Cho, Doo-Hee,Hwang, Joohyun,Huh, Jin Woo,Chu, Hye Yong,Lee, Jeong-Ik The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.3
In this work, we report on a new monitoring method for an organic light-emitting diode (OLED) panel for lighting by optical sensing of the wave-guided light in the substrate. Using microlens array films, the wave-guided light was extracted into the edge or back side of the panel to be monitored by a photodiode. The luminance of the extracted light was measured as linearly proportional to the front light. Thus, by converting the extracted light into photo voltage, monitoring the luminance change occurring in the OLED is possible. Based on the results and concepts, we have proposed a photodiode-equipped driving circuit which can generate compensated driving current for uniform luminance of OLED panels.
(Han Chu Lee),(Sung Ae Jung),(Hye Kyung Jung),(Sun Young Yi),(Doe Young Kim),(Il Hwan Moon),(Sung Su Park) 대한내과학회 1999 The Korean Journal of Internal Medicine Vol.14 No.2
N/A Objectives:The hepatotoxicity of acetaminophen is not a result of the parent compound but is mediated by its reactive metabolite N-acetyl-p-benzoquinone imine. Cytochrome P4502E1 (CYP2E1) is the principal enzyme of this biotransformation, which accounts for approximately 52% of the bioactivation in human microsomes. Recently, chlormethiazole, a sedative drug, is reported to be an efficient inhibitor of CYP2E1 activity in human beings. In this study we wished to evaluate whether chlormethiazole, an inhibitor of CYP2E1, could prevent acetaminophen-induced liver injury in mice. Methods:Acetaminophen, at doses ranging from 200 to 600 mg/kg, was injected into the peritoneum of female C57BL/6 inbred mice fasted for four hours. Chlormethiazole (60 mg/kg) or 5% dextrose water was given 30 min before or 2 h after acetaminophen. Serum aminotransferase activities, histologic index score, survival rate and hepatic malondialdehyde levels were compared. Results:Pretreatment with chlormethiazole 30 min before 400 mg/kg of acetaminophen completely inhibited acetaminophen-induced liver injury (median 118.5 U/L, range 75 to 142 vs. 14070 U/L, range 5980 to 27680 for AST; 49 U/L, range 41 to 64 vs. 15330 U/L, range 13920 to 15940 for ALT). In mice receiving chlormethiazole 2 h after acetaminophen, the mean AST and ALT levels were also less elevated, reaching only 20% of the value of acetaminophen-only group. These protective effects were confirmed histologically. Whereas more than 50% of mice died at 500 mg/kg of acetaminophen, all the mice pretreated with chlormethiazole survived at the same dose. Conclusion:Chlormethiazole effectively reduces acetaminophen-induced liver injury in mice. Further studies are needed to assess its role in humans.