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Revealing the Spatial Distribution of Inorganic Elements in Rice Grains
Jeon, Ji Suk,Choi, Sung Hwa,Lee, Ji Yeon,Kim, Ji A,Yang, Young Mi,Song, Eun Ji,Kim, Jae Sung,Yang, Jung Seok,Kim, Kyong Su,Yoo, Jong Hyun,Kim, Hai Dong,Park, Kyung Su Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.11
Femtosecond laser ablation (fs LA) was used in this study to identify pollution by heavy metals and the distribution of elemental nutrients at different rice milling ratios. Polished rice (degrees of milling of 3, 5, 7, 9, and 11) was collected from major Korean supermarkets and one sample thereof was selected. An internal quality control experiment was conducted using a rice flour certified reference material from the Korea Research Institute of Standards and Science (KRISS CRM) for the evaluation of the efficacy. To assess the effectiveness of the analysis method, the reliability was validated using a food analysis performance assessment scheme (FAPAS), with chili powder serving as an external quality control. The results of the analysis of the inorganic elements Ti, Ca, Al, Fe and Mn in white and brown rice with degrees of milling of 3, 5, 7, 9 and 11 using ICP-MS, ICP-OES and AAS revealed contents of 0.40, 49.2, 2.43, 5.36 and 10.3 mg/kg in white rice and 0.59, 78.0, 7.52, 11.0 and 18.5 mg/kg in brown rice, respectively. Among the elements, there were remarkable differences in the measured contents. By comparing the contents of the elements at different degrees of milling, Ti, Co, As, Ca, Al, Cu, Fe, and Mn were determined to be distributed on the surface of the rice grains, whereas the contents of Cd and Pb increased toward the center of the rice grains, and Si was evenly distributed. After the quantitative analysis of rice samples polished to different degrees of milling, Ca and Al, which were contained in large amounts, and Si were analyzed with specificity by fs LA. The results show that Ca and Al were distributed in the rice husk (protective covering of rice) and Si was distributed in all parts of the rice.
Synergistic Effects of Leflunomide and Benazepril in Streptozotocin-Induced Diabetic Nephropathy
Jin, Hua,Piao, Shang Guo,Jin, Ji Zhe,Jin, Ying Shun,Cui, Zhen Hua,Jin, Hai Feng,Zheng, Hai Lan,Li, Jin Ji,Jiang, Yu Ji,Yang, Chul Woo,Li, Can S.Karger 2014 The Nephron Journals Vol.126 No.3
<P>Abstract</P><P><B><I>Background:</I></B> Leflunomide (LEF) and benazepril have renoprotective effects on diabetic nephropathy (DN) through their anti-inflammatory and anti-fibrotic activities. This study investigated whether combined treatment using LEF and benazepril affords superior protection compared with the respective monotherapies. <B><I>Methods:</I></B> Diabetes was induced with streptozotocin (STZ, 65 mg/kg) by intraperitoneal injection in male Wistar rats. Two weeks after STZ injection, diabetic rats were treated daily for 12 weeks with LEF (10 mg/kg), benazepril (10 mg/kg), or a combination of both. Basic parameters (body weight, fasting blood glucose level, and 24 h urinary protein excretion), histopathology, inflammatory [inflammatory cell infiltration (ED-1), monocyte chemoattractant protein-1 (MCP-1), and Toll-like receptor-2 (TLR-2)] and glomerulosclerotic factors [transforming growth factor-β<SUB>1</SUB> (TGF-β<SUB>1</SUB>) and connective tissue growth factor (CTGF)], and oxidative stress (8-hydroxy-2'-deoxyguanosine, 8-OHdG) were studied. <B><I>Results:</I></B> Benazepril or LEF treatment significantly prevented body weight loss and 24 h urinary protein excretion induced by diabetes; combined treatment with LEF and benazepril further improved these parameters compared with giving each drug alone (all p < 0.01). Increased expression of inflammatory (MCP-1 and TLR-2) and glomerulosclerotic (TGF-β<SUB>1</SUB> and CTGF) factors in diabetic rat kidney was reduced by treatment with either LEF or benazepril and was further reduced by the combined administration of the two drugs (p < 0.01). These effects were accompanied by suppression of urinary 8-OHdG excretion. There was no significant between-group difference in blood glucose level. <B><I>Conclusions:</I></B> LEF treatment lessens DN, and combined treatment with LEF and benazepril provides synergistic effects in preventing DN.</P><P>© 2014 S. Karger AG, Basel</P>
Fuzzy Control for Active Suspension System
Yang-Hai Nan,Jin-Wan Kim,Dong-Ji Xuan,Qian Ning,Young-Bae Kim 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.5
In this paper, a control strategy of active suspension based on fuzzy logic control has been investigated. Using incorporating feedback from force sensor to front and rear active suspension system, the control system improved the dynamic responses of the vehicle. A multi degree-of-freedom nonlinear model was co-simulated by MATLAB/Simulink and ADAMS/Car. The simulation results indicate that the proposed active suspension is very effective in the vibration isolation.
Design of Active Suspension System with Fuzzy Control
Yang-Hai Nan,Jin-Wan Kim,Dong-Ji Xuan,Qian Ning,Young-Bae Kim 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
In this paper, a control strategy of active suspension based on the fuzzy logic control has been investigated. Using incorporating feedback from force sensor at the front and rear active suspension system, the control system shows the improvement of the dynamic responses of the vehicle. A multi degree-of-freedom nonlinear model is co-simulated by MATLAB/Simulink and ADAMS/Car. The simulation results indicate that the proposed active suspension is very effective in the vibration isolation.
Hierarchical Control for Nonlinear Systems by Partial-state Feedback
Kaihong Yang,Hai-bo Ji 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.2
In this paper, the hierarchical control problem is rephrased and addressed that systematically tackles thedesign of hierarchical control law between the concrete system and the abstract system. The proposed way to thisproblem, on one hand, incorporates simulation function technique, and on the other hand, allows us to design apartial-state feedback hierarchical control law. Following this approach, we design two hierarchical control lawsfor nonlinear systems. Finally, an example illustrates this approach.
김지영 ( Ji Young Kim ),양승호 ( Seung Ho Yang ),홍성연 ( Seong Yeun Hong ),주대현 ( Dae Hyeon Choo ),오훈규 ( Hoon Kyu Oh ),박영찬 ( Young Chan Park ),정혜리 ( Hai Lee Chung ),김우택 ( Woo Taek Kim ) 대한주산의학회 2006 Perinatology Vol.17 No.2
Fetus in fetu는 500,000명당 한 명 정도의 유병률을 가진 신생아에서 복부종양의 매우 드문 원인이다. 이것은 일란성 이양막 일융모막 쌍생아에서 배아 분화 과정 초기에 한 태아의 개체내로 다른 태아가 봉입되면서 발생하는 것으로 알려져 있다. 본 증례는 후복막강에 fetus in fetu가 발견된 생후 3일된 남아의 경우로 수술로 적출된 종양에서 척추, 2개의 팔, 다리, 음경, 고환이 발견되었다. 이러한 골격과 기관생성은 기형종과의 감별점이다. 지금까지 100여개의 증례가 보고되었고 그 중 대부분이 복강내에 위치하고 있었다. 본 증례도 만삭으로 태어난 신생아의 후복막강에서 잘 분화된 태아가 발견되어 보고하는 바이다. Fetus in fetu is an extremely uncommon cause of abdominal mass in the neonate with an incidence of 1 in 500,000 births. This is thought to occur when a monozygotic, diamniotic twin is incorporated into the body of its sibling early in embryonic development. A case of retroperitoneal fetus in fetu in a 3 day old male infant is reported, the excised round mass contained the vertebral coluum, 2 feet, 2 arms, small penis and testis. The presence of vertebral axis and organogenesis differentiates it from a teratoma. More than 100 cases of fetus in fetu have been reported, most of which have been in the abdomen. We report a case of a well developed fetus in the retroperitoneal area of a neonate delivered at term.
( Da Hai Yu ),( Ji Yu Yang ),( Fei Teng ),( Li Li Feng ),( Xue Xun Fang ),( He Jun Ren ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.7
The mature landfill leachate, which is characterized by a high concentration of ammonia nitrogen (NH3-N) and humic acid (HA), poses a challenge to biotreatment methods, due to the constituent toxicity and low biodegradable fraction of the organics. In this study, we applied bioaugmentation technology in landfill leachate degradation by introducing a domesticated NH3-N and HA resistant bacteria strain, which was identified as Bacillus cereus (abbreviated as B. cereus Jlu) and Enterococcus casseliflavus (abbreviated as E. casseliflavus Jlu), respectively. The isolated strains exhibited excellent tolerant ability for NH3-N and HA and they could also greatly improved the COD (chemical oxygen demand), NH3-N and HA removal rate, and efficiency of bioaugmentation degradation of landfill leachate. Only 3 days was required for the domesticated bacteria to remove about 70.0% COD, compared with 9 days`` degradation for the undomesticated (autochthonous) bacteria to obtain a similar removal rate. An orthogonal array was then used to further improve the COD and NH3-N removal rate. Under the optimum condition, the COD removal rate in leachate by using E. casseliflavus Jlu and B. cereus Jlu increased to 86.0% and 90.0%, respectively after, 2 days of degradation. The simultaneous removal of NH3-N and HA with more than 50% and 40% removal rate in leachate by employing the sole screened strain was first observed.
Ma, Ji-Yong,Yan, Hai-Jun,Yang, Zhen-Hua,Gu, Wei Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
MicroRNA-27a (miR-27a) is deemed to be an oncogene that plays an important role in development of various cancers, and single nucleotide polymorphism (SNP) of miR-27a can influence the maturation or aberrant expression of hsa-miR27a, resulting in increased risk of cancer and poor prognosis for non-small cell lung cancer (NSCLC). This study aimed to assess the effects of rs895819 within miR-27a on susceptibility and prognosis of NSCLC patients in 560 clinical confirmed cases and 568 healthy check-up individuals. Adjusted odds/hazard ratios (ORs/HRs) and 95% confidential intervals (CIs) were calculated to evaluate the association between rs895819 and the risk and prognosis of NSCLC. The results showed that allele A and genotype GG of rs895819 were significantly associated with an increased risk of NSCLC (38.9% vs 30.8%, adjusted OR=1.26, 95%CI=1.23-1.29 for allele G vs A; 18.1% vs 11.7%, adjusted OR=1.67, 95%CI=1.59-1.75 for genotype GG vs AA). Moreover, positive associations were also observed in dominant and recessive models (53.7% vs 49.9%, adjusted OR=1.17, 95%CI=1.13-1.20 for GG/AG vs AA; 18.1% vs 11.7%, adjusted=1.65, 95%CI=1.58-1.73). However, no significant association was found between rs895819 and the prognosis of NSCLC in genotype, dominant and recessive models. These results suggested that miR-27a might be involved in NSCLC carcinogenesis, but not in progression of NSCLC. The allele G, genotype GG and allele G carrier (GG/AG vs AA) of rs895819 might be genetic susceptible factors for NSCLC. Further multi-central, large sample size and well-designed prospective studies as well as functional studies are warranted to verify our findings.