微量合金鋼의 機械的特質 向上에 미치는 析出物의 影響

李相允,李相雄,李熙太 동아대학교 공과대학 부설 한국자원개발연구소 1987 硏究報告 Vol.11 No.2

This study has been performed to investigate into various tensile properties of Fe-1.32% Si-0.34% C steel either quenched and tempered or isothermal-transformed after austenitizing at temperatures in the range of which both ferrite and austenite are present. The results obtained from the experiment are as follows; 1) The ductility is considerably improved by the addition of Si due to the fact that ferrite solution-strengthened and the formation of precipitates in ferrite is retarded. 2) Tensile test has shown that tensile properties of specimens isothermal-transformation treated are more improved as compared to the quenching and tempering treatment. 3) The saving of heat treatment energy and the reduction of manufacturing time can be achieved by simplifying heat treatment cycles to obtain better tensile properties than those generally obtainable from dual phase steels.

Henry 4세 즉위의 정당성

李海雄 한국강원영어영문학회 1994 영어영문학 Vol.- No.13

Since E.M.W. Tillyard and Lily B. Campbell gave in 1940s to the moden criticism on the Shakespeare's histoy plays, there has been a long debate among critics on whether or not Bolingbroke's grip of the crown out of the anointed king Richard. This argument is, in other words, that between the critics who take the side of divine kingship and those who see the kingship as one of the practical jobs, the success of which wholly depends on the political capability and moral quality of a monarch. The concept of kingship of the pro-Richard critics is based upon the doctrines of Tudor Myth, or 'Kmg's Two Body'energized by the Elizabethan political theorists like Cecil or Ralegh, who strongly insisted that King's Body politic cannot do any wrong. But Shakespeare's Richard is depicted as a problematic monarch who is not only politically incapable and emotionally unstable, but also violates the principle and law of the state. In Richard Ⅱ, he is described as a lung whose defects may legitimize, as Robert Parsons justifies dethronement of a bad king, Bolingbroke's accession to the throne. Beside Richard's faults, such points as Bolingbroke's moral, political ethics and achievements may serve to some extent as objective criteria to judge his regime right or wrong. Henry's moral as a ruler can be recognized by his idea of kingship, which is so practical and man-centered that he regards it a painful duty demanding its owner's sacrifice. Througout the plays Henry is never seen to seek pleasure or enjoy king's privilege, but found to be possessed by care and concern about the problems in education of Prince Hal and pacification of the rebellions. Upbringing of young Prince Hal to an able ruler occupies one of Henry's most serious concerns. Shakespeare uses a dramatic irony by which the characters on stage are scarecely exposed to the true entity of Hal till he makes a reconciliation with his father in Part 2, Act Ⅳ, scene v. Audiences are invited to learn the Henry's question of succession being solved when they see the competent rival Hotspur falls by Hal's sword and Hal recognize at his father's deathbed the essential meaning of the crown as a hard work. Bolingbroke's another main concern is to pacify the rebellions and reunify the kingdom split into factions by the feudalistic barons like Nothumberland, making it possible for his successor to rule the commonwealth on a more stabilized political ground. In spite of the conclusion that Shakespeare seems to render justice and legitimacy to Henry's enthronement, a great number of questions about it and as many answers can be given to them for Shakespeare's plays are widely open enough to allow various reading. Shakespeare only presents the complicated natures of human political life and the world of history in the form of theater.

소 부신수질 Muscarine 수용체의 성질

이신웅,이해태 영남대학교 약품개발연구소 1995 영남대학교 약품개발연구소 연구업적집 Vol.5 No.-

The nature of the muscarinic receptors in bovine adrenal medulla was investigated in this study. [³H]Quinuclidinyl benzilate(QNB) specifically bound to a single class of muscarinic receptor with a Kp value of about 70 pM in bovine adrenal medullary. cardiac ventricular and ileal homogenates. Pirenzepine inhibition curves of [³H]QNB binding to cardiac ventricular and ileal homogenates were steep, indicating the presence of a single class of binding site for pirenzepine with a Ki value of 990 nM and 508 nM, respectively. However, pirenzepine/[³H]QNB competition binding curves in adrenal medulla suggested the presence of two binding sites (Hill coefficient=0.59) with a high(M₁) and a low(M₂) affinity. Respective Ki values for pirenzepine were 16 nM and 633 nM, with 44% of total sites having a high affinity(M₃). Gallamine, which is selective to cardiac M₂-receptor, inhibited [³H]QNB binding to adrenal medullary, cardiac ventricular and ileal homogenates with Ki values of 12 μM, 6 μM and 13 μM, respectively. Thus, the binding affinities of pirenzepine and gallamine for M₂-receptor in adrenal medulla were similar to those in ileum, which contains the M₃-receptor. These results indicate that the M_(-1) and M_(3-) muscarinic receptor subtypes coexist in the bovine adrenal medulla.

HIV 감염 환자에서 발생한 편평 콘딜롬 1예

이해웅,오상현,장성은,최지호,문기찬,고재경 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.4

Streptokinase와 Plasminogen의 활성 복합체에 대한 생화학적 특성

이현재,전형균,이해진,김태성,김연웅 慶尙大學校 1988 論文集 Vol.27 No.2

Fig 1과 Fig 2의 실험 결과에 의하면 streptokinase에 의한 plasminogen의 활성화 기작은 먼저 streptokinase와 plasminogen 결합하여 복합체를 만들고 그 다음 다른 분자의 streptokinase에 의한 plasminogen을 streptokinase에 의한 plasmin으로 활성화 한다고 생각되었다.그리고 원래 효소활성이 없는 streptokinase량이 plasminogen보다 과량으로 존재하게 되면 전체 esterolytic 활성도는 plasminogen 의 량에 의존하게 될 것이다.Fig 3의 실험에서 streptokinase plasminogen 복합체의 정량적인 구성 비율을 조사하였더니 plasminogen 1㎍에 0.5㎍의 streptokinase가 결합하였다. 이는 보고된 plasminogen의 분자량을 87.000(10) 그리고 streptokinase분자량이 47.000(6)으로 계산하면 각각 한 분자씩 결합하고 있음을 알 수 있었다. 이 결과는 Fig. 1의 결과를 보충할 수 있는 data이다. streptokinase plasminogen 복합체의 생화학적 특성을 조사하기 위하여 복합체만의 활성을 assay 할 수 있는 방법을 고안하였다. 실험결과 soybean trysin inhibitor를 사용하면 plasminogen의 활성화에 의하여 생성된 plasmin의 esterolytic 활성은 완벽하게 저해할 수 있었으나 streptokinase plasminogen 복합체의 활성은 저해하지 못하였으므로 soybean trypsin inhibitor를 첨가하여plasmin활성을 제거하여 순수한 복합체만의 활성을 측정할 수 있었다.(Fig.5).그러나 pancreatic tyrpsin inhibitor는 Plasmin 뿐만 아니라 streptokinase plasminogen복합체의 활성을 모두 저해할 수 있었으므로 이 inhibitor 는 복합체의 활성을 측정하는데 사용하지 않았다. (Fig.4). 두가지 inhibitor의 복합체에 대한 상이한 저해 효과는 복합체의 활성화 자리 (active site)에 두 inhibitor 가 결합하고난 후 기질이 출입할 수 있는 공간의 넓이에 의한 효과인 것으로 생각되었다 (Table 1).따라서 soybean trypsin inhibitor을 이용한 assay는 원래의 생화확적 특성에 영향이 없는 것으로 생각되었다. 복합체의 esterolytic 반응은 빠른 첫 번째 반응 그리고 그 이후 늦은 두 번째 반응으로 진행되는 biphasic한 형태를 보여 주었다(Fig.7).이 반응 기작은 알려진 serine protease들이 acyl중간체을 이용한 biphasic 반응 기작과 유사한 형태이었다. 활성화 자리에 위치하고 있는 여러 작용기들을 확인하기 위한 기초 실험으로써 pH에 따른 esterolytic활성을 측정한 결과 최대 활성을 보이는 pH는 7.5이었다.(Fig.8). 이 근처의 pKa 값을 가지고 아미노산은 histidine 종류을 생각할 수있을 것이다. The kinetic data suggest that streptokinase interacts with plasminogen to become an active complex which in turn. activates another molecule of plasminogen to plasmin. This complex was fromed stoichiometrically at 1:1 molar ratio. A series of experiment were carried out to find the condition that the streptokinase plasminogen complex activities free from plasmin could be monitered. The soybean trypsin inhibitor wsas used to assay the activity of streptokinase-plasminogen complex. The lack of inhibiton of esterase activity by soybean trypsin inhibitor was thought to be the size of the protein in active site. The esterolytic reaction by streptokinase-plasminogen complex showed biphasic pattern. The pH profile showed typical bell-shape and optimal pH for streptokinas-plasminogen complex showed biphasic pattern. The pH profile showed a typical bell-shape and optimal pH for streptokinas-plasminogen complex was 7.5.

Henry Ⅴ에 나타난 이데올로기와 修辭법

이해웅 한국강원영어영문학회 1998 영어영문학 Vol.17 No.2

In Henry Ⅴ Shakespeare depicts Henry Ⅴ as a king who is kept strictly in the human boundary and, therefore, obliged to exert his political ability to legitimate and maintain his sovereignty. As a way to obtain his goals, Henry employs an ideological strategy of English national prestige and patriotism, which he seeks to implant in his subjects by means of rhetoric. Henry is an alchemist who can change the worst metal into the best one and vise versa. His rhetoric varies to the different situations, which are toward what Henry intends. He is holding the reign of language, the signifier which creates a new signified and deletes the old: his long and fiery speech against Scroop createsa a new traitor who is quite different from what the convict has been. Henry's language is a display of power itself: his threatening speech at Harfleur generates an emotional power stronger than any physical one; his Crispian speech produces a lot more meanings which make the soldiers run the risk of death. The visible results such as legitimacy of Henry's regime, concentration of national power, the conquest of France and the hightening of national prestige prove the materialistic nature of speech and ideology. By showing England's loss of France and the bloody power-struggles among the nobles during the reign of Henry Ⅳ, Shakespeare emphasizes in Henry Ⅴ that all the human accomplishments are subject to history and an able ruler, therefore, must possess the political ability to create new ideology and maintain it.

하시모토 병과 동반된 악성 빈혈 1 예

한 호,안명주,최정혜,이창범,이영열,최일영,김인순,이웅수 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

Pernicious anemia is the most common cause of vitamin B12 deficiency and is caused by autoimmune destruction of parietal cell containing gastric mucosa region. This disease is significantly associated with autoimmune endocrinopathies and anti-receptor autoimmune disease. We report here a case of 26-year old man who was diagnosed pernicious anemia with high level of autoantibody titer (antithyroglobulin antibody 1:25,600 and antimicromosomal antibody 1:6,400) indicating subclinical Hashimoto's thyroiditis. Since other autoimmune diseases are frequently associated with pernicious anemia even without evidence of clinical symptoms, screening test for the presence of autoimmune disease should be evaluated in these patients.

플립칩에서 UBM을 고려한 무연 솔더 접합부의 열피로 해석 모사

김성걸,김주영,이해웅 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

This paper describes in detail the life prediction models for 95.5Sn-4.0Ag-0.5Cu solder joints of Flip chip package. A 3D Finite element slice model was used to simulate the viscoplastic behavior of the solder. Two different solder bump pitches were analyzed and the effects of underfill packages were studied, Consequently, this numerical study shows that solder joints with underfill has better fatigue life than solder joints without underfill. Also, 300㎛ pitch solder joints has a longer life than 150㎛ pitch solder joints.

人蔘이 自然發生高血壓쥐에 있어서 血壓 및 血漿 Renin 活性度에 미치는 影響에 關한 實驗的 硏究

孫宜錫,朴陞哲,許鳳烈,李禎均,林憲吉,咸駿洙,梁忠模,韓哲洙,朴贊雄,金海中 대한의학협회 1979 대한의학협회지 Vol.22 No.9

Interstitial Granulomatous Dermatitis with Plaques Associated with Antiphospholipid Syndrome

( Hae Woong Lee ),( Woo Jin Yun ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ),( Kee Chan Moon ),( Jai Kyoung Koh ) 대한피부과학회 2005 초록집 Vol.43 No.10