신경회로망에서 뉴런간의 연결도를 이용한 4백 배치 문제 해결 알고리즘

현해진,김덕주,강부식,이기태,임재윤 濟州大學校 工科大學 産業技術硏究所 1993 産業技術硏究報告 Vol.4 No.-

In this paper we have proposed a method for solving a four-coloring problem using adjusted information transmission between adjacent neurons in neural networks. These algorithms are based on McCclloch-Pitts binary neuron model neural networks. If a map shares n regions, a 4×n neural array is used to color a map of n regions where each neuron as a processing element performs it. By programming these algorithm by a C-language in IBM PC 486 DX and adapting it to various examples, we have showed the ability of our system. If one neuron is selected among four neurons, the strength of order three neurons is wakened. So, by transmitting the information of selected neuron, adjacent neurons cannot share the same color.

자궁경부종양에서 HPVDNAChip^(�) 및 Hybrid Capture Ⅱ^(TM)검사를 이용한 인유두종 바이러스의 검출

여소진,김달수,남계현,심일구,김태희,이해혁,이권해 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.2

목적 : 인유두종 바이러스는 자궁경부암의 의의있는 원인 인자이다. 이 연구의 목적은 HPVDNAChip??검사를 이용하여 정상, 전암병변, 침윤성 경부암의 인유두종 바이러스의 분포를 알아보고 그 결과를 Hybrid CaptureⅡ^(^(TM)) 검사와 비교하였다. 연구 방법 : 149명의 대상환자 중 57명은 병변이 없었고, 59명은 전암 병변이었으며, 33명은 침윤성 경부암이었다. HPVDNAChip??검사와 이 검사처럼 아형 66, 69를 제외한 고위험군(HPV-16/18/31/33/35/45/51/52/56/58/59/68) 인유두종 바이러스를 검사할 수 있는 Hybrid CaptureⅡ^(^(TM))검사를 이용하여 연구하였다. 결과 : 두 검사 모두 인유두종 바이러스를 검사하는 데 유용하였고, 결과가 의의있게 일치하였다(kappa value 0.721, p<0.01). Hybrid CaptureⅡ^(^(TM))검사에서 양성이나 HPVDNAChip??검사에서 음성인 경우는 18명(12.1%)으로 평균 Hybrid CaptureⅡ^(^(TM))값이 120.7±233.0 (mean±SD)이였고, 두 검사 모두 양성인 경우의 Hybrid CaptureⅡ^(^(TM))값은 448.1±732.8 (mean±SD)이였다. Hybrid CaptureⅡ^(^(TM))검사의 민감도는 94.6%이고, 특이도는 78.9%였고 HPVDNAChip??검사의 민감도는 83.7%이고, 특이도는 89.5%였다. HPVDNAChip??검사는 모두 15가지의 고위험군의 인유두종 바이러스 아형을 알아낼 수 있으며 아형 16이 전암병변(28.8%, 15/59)과 침윤성 경부암(48.5%, 19/33)에서 가장 흔한 아형이었으며 그 다음으로 흔한 아형은 58이었다. 결론 : HPVDNAChip??검사는 Hybrid CaptureⅡ^(^(TM))검사처럼 인유두종 바이러스 검사에 매우 민감하고 유용한 검사이다. HPVDNAChip??검사는 Hybrid CaptureⅡ^(^(TM))검사와 비교할 때, 인유두종 바이러스의 아형과 중복감염에 대한 정보를 준다. 앞으로 HPVDNAChip??검사의 자궁경부암의 선별검사로서의 가치에 대한 연구가 더 필요하다. Objective : Human Papillomavirus (HPV) is well known as one of the major risk HPVDNAChip?? factors for cervical cancer. The purpose of this study is to know HPV genotype distribution in women with normal cervix, precancerous lesion, and invasive cervical cancer by HPVDNAChip?? test. In addition, the result of HPVDNAChip?? test was compared with Hybrid CaptureⅡ^(TM) system for HPV detection. Methods : One hundred forty nine patients were included in this study. 57 women had normal cervix, 59 women had precancerous lesion, and 33 women had invasive cervical cancer. We tested them with two method for detection of Human Papillomavirus (HPV) by HPVDNAChip?? test and Hybrid CaptureⅡ^(TM) system. Hybrid CaptureⅡ^(TM) test can detect same high-risk HPVs (16/18/31/33/35/39/45/51/52/56/58/59/68) with HPVDNAChip?? test which can detect additional 66 & 69 high risk types of HPV. Results : Both methods for the detection of HPV were useful tests. The correlation between the results of two methods was very significant (kappa value 0.721 [p<0.01]). Positive Hybrid CaptureⅡ^(TM) test and negative HPVDNAChip?? test group were 18 women (12.1%) and average Hybrid CaptureⅡ^(TM) titer value of this group was 120.7±233.0 (mean±SD), positive Hybrid CaptureⅡ^(TM) test and positive HPVDNAChip?? test group were 84 women (54.4%) and average titer was 448.1±732.8. The Hybrid CaptureⅡ^(TM) test showed a sensitivity of 94.6% and a specificity of 78.9% and the HPVDNAChip?? test showed a sensitivity of 83.7% and a specificity of 89.5%. HPVDNAChip?? test detected total 14 genotype of HPV. HPV-16 was 28.8% (15/59) in precancerous lesion and 48.5% (19/33) in invasive cancer, most common in both groups. Next common type HPV-58 was 25.4% (12/59) in precancerous lesion and 9.1% (3/33) in invasive cancer. Conclusion : HPVDNAChip?? test is very sensitive and effective method for detection of Human Papillomavirus (HPV) infection as Hybrid CaptureⅡTMtest. In comparison with Hybrid CaptureⅡ^(TM) test, HPV genotype and multiple HPV infection information can be given by HPVDNAChip?? test. Further study will be needed to know the value of screening of cervical cancer by HPVDNAChip?? test in future.

블록 암호화를 위한 Blowfish 구현

성해경,박종태,노진수,이강현 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.2

Blowfish is a symmetric block cipher that can be used as a drop-in replacement for DES or IDEA. It takes a variable-length key, from 32bits to 448bits, making it ideal for both domestic and exportable use. In this paper, the Blowfish unit is designed using pipeline architecture and correctly implements the algorithm with a focus on ease-of-design and ease-of-use without sacrificing too much speed or size. For the real time process of Blowfish, it is required that high-speed operation and small size hardware. So, the scheme of new adders designed has all advantages abstracted from other adders. As a result of this new adder designed, area cost increases by 1.05 times but the operation speed increases by 1.2 times.

사인에 의한 즉시형 과민반응의 억제 효과

신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-

We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.

시각 특성을 고려한 웨이브릿 변환 비디오 압축

양해권,김진태 群山大學校 情報通信技術硏究所 1998 情報通信技術硏究論文集 Vol.2 No.-

In this paper, we will compress the data of video signal using motion compensation and wavelet transform method. It is abbreviate to process have not large gain that analysing human visual characteristic for video signal and is compressed to the high portion without low resolution for video signal by abbreviated unsensitive information for human visual. In the result of simulation with 'Football' and 'People', we get high resolution under compress of frame per 30:1.

미생물을 이용한 해조류의 가수분해 및 이용 : Ⅱ. 돌가사리, 톳 및 가시파래를 가수분해시키는 미생물군의 탐색 Ⅱ. Screening of Microfloras Involved in Hydrolysis of Seaweed Tenella, Seaweed Fusiforme and Green Laver

김해섭,배태진 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.3

해조류 조직을 가수분해시켜 기호성 및 응용성이 높은 액상원료로 가공하는 기술 개발의 일환으로 우선 자연계에 존재하는 미생물로서 산, 논, 밭, 해변 및 어판장에서 약 200종류의 미생물군 시료를 수집하여 해조의 조직파괴가 인정되는 8군의 미생물 시료를 사용하여 돌가사리, 톳 및 가시파래의 조직파괴와 가수 분해 가능성에대하여 검토하고, 추출액 중의 전당과 환원당을 측정하여 추출율과 분해율을 비교하였다. 그 결과 돌가사리, 톳 및 가시파래의 전당 추출량과 추출율은 각각 담수에서 채취한 미생물군 시료 (No. 27번), 부식한 식물에서 채취한 미생물군 시료 (No. 8번) 및 담수에서 채취한 미생물군 시료가 가장 높은 값을 나타내었고, 환원당의 추출량과 시료가 가장 높은 값을 나타내었고, 환원당의 추출량과 추출율에서는 각각 8번, 8번 및 27번 미생물 군 시료가 가장 높은 값을 나타내었다. 분해율은 전당의 추출율도 상당히 높으면서 환원당의 추출이 가장 높았던 실험구들이 각각의 해조에서 가장 높은 분해율을 나타내는 결과를 얻었다. 따라서 이들 자연계에서 채취한 미생물군 시료중에 해조 조체를 파괴시키고, 또한 해조에 다량 함유되어 있는 당을 비롯한 유용성분의 추출을 용이하게 하며, 해조를 가수분해시키는 효소를 가진 미생물이 존재할 것으로 판단되었으며, 또한 이들 미생물군에서 단일 또는 복합 해조가수분해 미생물 및 효소의 생산이 가능할 것으로 기대되었다. The purpose of this study is screening of microfloras involved in hydrolysis of seaweed tenella, seaweed fusiforme and green laver. This is a part of studies on the hydrolysis of seaweed using microorganisms. First, about two hundred microflora samples were obtained from mountain, rice field, dry field, sea, seaside and fish market in the vicinity of Yeosu. Thiry-three microflora samples were screened from the destruction of tissue in sea tangle and sea mustard . It was sufficient that results of the naked eye observation were obtained at eight microflora samples as a feces of bull, a decayed pine tree, a soil of dry field, the mud of the banks in a rice field, the water of a ditch in a rice field, the weed of the banks in a rice field, the water in a rice field and leaved in the air. Above all, extraction rate and contents of reducing sugar in extracts of seaweeds added a decayed pine tree (sample No. 8) and the water of a ditch in a rice field (sample No. 27) were showed high value. And the value of chemical analysis of the sample is much better in comparison with control. Accordingly the hydrolysis of seaweed using mcriorganisms in the inside of these microflora samples can be possible.

저빈도 반복성 경두개 자기자극이 정상인의 시각적 단기 기억에 미치는 영향

오해정,김원,이경욱,박원명,전태연,한진희,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequencyr TMS on visual short term memory. Methods : Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results : No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion : This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiathc fields without any interference of cognitive function.

메틸렌 클로라이드에 의한 폐장염

장규진,박종태,,김은경,김병권,김해준 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Objectives: The authors report a case of pneumonitis caused by methylene chloride (MC). Methods: The patient was examined and diagnosed by clinical, radiologic, laboratorial and medical evaluation. The concentration of MC in the factory was measured to determine the exposure level. Results: The patient had an infiltration in chest X-ray, which underwent rapid relief of radiological finding, respiratory acidosis and hypoxemia in arterial blood gas analysis, and a ground-glass opacity in high resolution computerized tomography. MC was the only exposed chemical compound in this case. The concentration of MC was 39.9 ppm in the factory. Conclusions: We diagnosed this to be a case of pneumonitis by MC based on clinical laboratory findings, exposure history to MC and MC concentration in the factory.

Cyclophosphamide 투여 흰쥐에서 비타민 A가 창상파열력에 미치는 영향에 관한 실험적 연구

조해석,정상훈,임풍,김진철,안상태 大韓成形外科學會 1985 Archives of Plastic Surgery Vol.12 No.1

Cyclophosphamide lays restraints upon production of fibroblast and collagen fiber and reduce wound burst strength by acting on fibroblast in acute inflammatory phase. Vitamin A is known to increase inflammatory reaction by exerting an effect upon inflammatory cells in the beginning of the wound healing process. It shows contrary effect to cyclophosphamide. In order to study the influence of vitamin A over wound healing delay induced by cyclophosphamide in rats, we observed and compared the wound burst strength of cyclophosphamide and vitamin A combined treated group with those of control and cyclophosphamide treated group. Wound burst strength of each group was measured in the skin segments of 2×4cm obtained from the operation sites at the 3rd, 5th, 7th and 14th postoperative days after making 5cm incision and suture at the back of 72 rats. Results of the experiment are as follows; 1. Wound burst strength in control group increases slowly as days go by and shows trends of sudden increase between the 5th and 7th postoperative days. 2. Wound burst strength in cyclophosphamide treated group is markedly less than that in control group. 3. Wound burst strength in cyclophosphamide and vitamin a combined treated group shows similar level to that in control group. 4. Body weight in cyclophosphamide treated group reduces gradually as days go by. But there's no weight reduction in cyclophosphamide and vitamin A combined treated group. Judging from these results, we found the fact that vitamin A could prevent or recuperate the side effects of cyclophosphamide, delay of wound healing and worsening of general condition.

냉동생지의 제조 및 최적 해동조건 연구

이수태,기해진,정순택,박양균 木浦大學校 工業技術硏究所 2000 工業技術硏究誌 Vol.10 No.-

Frozen dough of two flour, Tazo and Tazo-S, and two thawing, room and cold temperature, were determined to qualified bread quality. For best bread quality from frozen doughs, very strong flour should be used. Frozen doughs are increasingly being produced in the baking industry even though they generally provide bread with lower loaf volume than dose unfrozen fresh dough. Several investigators have reported that the major changes in doughs that have been frozen are related to yeast. During the dough fermentation, yeast produces carbon dioxide and flavor compounds. Loaf volume decreased markedly with freezing and thawing, and gradually during frozen storage.