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고옥현,강형룡,유진철,김경수,홍석순,김영수,황화영,하재천 조선대학교 약학연구소 1992 藥學硏究誌 Vol.14 No.1
7β[5-(Substituted) phenyl-2H-tetrazol-2-yl]acetamidocephalospranic acid, 7β-(5-Diphnenyl-methyl-2H-tetrazol-2-yl) acetamidocephalosporanic acid and 7β-[5-(Substituted)-4-phenyl-1.2.4-triazol2-yl]thioacetamidocephalosporanic acid were synthesized and tested in vitro antimicrobial activity. These compounds exhibited good antimicrobial activity against Gram-positive bacteria whereas most compounds showed decreased antimicrobial activity against Gram-negative bacteria
Hwang, Jung Hye,An, Sang Mi,Kwon, Seul Gi,Park, Da Hye,Kim, Tae Wan,Kang, Deok Gyung,Yu, Go Eun,Kim, Il-Suk,Park, Hwa Chun,Ha, Jeongim,Kim, Chul Wook Informa UK (TaylorFrancis) 2017 Animal biotechnology Vol.28 No.4
<P>Postmortem pH is a main factor influencing the meat quality in pigs. This study investigated the association of postmortem pH with single-nucleotide polymorphisms (SNPs) in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. The study included 437 pigs, and genotyping was conducted using the GoldenGate Assay (Illumina, San Diego, CA, USA). DHRS4, SERPING1, and APOR polymorphisms were significantly associated with pH(45) or pH(24) (p<0.05). SERPING1 was also statistically significantly associated with water holding capacity (p<0.05), which is closely associated with postmortem pH. These results suggest that SNPs in the DHRS4, SERPING1, and APOR genes have potential for use as genetic markers for the meat quality in pigs.</P>
Development of Ergonomic Backrest for Office Chairs
Chang Yong Kim,Gyung Yong Song,Yeon Sik Jang,Hyo Eun Ko,Hee Dong Kim,Gemus Park,Jung Bo Hwang,Hwa Shik Jung 대한인간공학회 2015 大韓人間工學會誌 Vol.34 No.2
Objective: This study aims to develop and scientifically investigate the efficacy of the Spine S-curve Reactive Backrest that responds to the spine curvature of the user when seated, and maintains and enhances the natural S-curve of the lower back, thereby helping to relieve fatigue, correct posture and prevent spine deformities. Background: The focus of current development, design guidelines and/or standards for office chairs is mainly placed on the chair"s dimensions, incline angle, adjusting features and lumbar support. Research and development was called for developing a chair backrest that maintains and improves the S-curve of the full spine. Method: The Spine S-curve Reactive Backrest was ergonomically designed to maintain correct posture and enhance user comfort. When leaned on, the backrest responds to the user"s spine line and the whole lower back sits closely against the backrest, thereby aligning the user"s lower back and backrest as one to maintain and improve the natural S-curve formation of the spine. In order to evaluate the efficacy of the newly designed chair (new design) and the comparison target (chair), five male college students of standard body type with normal spine curvature were selected as test subjects, and a motion analyzer and electromyography were utilized to measure Scurve and erector spinae muscle activity when seated. Results: The spine S-curve was better maintained and improved when sitting in the new design than in the comparison chair. Particularly notable was the greater displacement gap of the thoracic spine than the cervical spine, and also that of the lumbar more than the thoracic spine, with the increase of the backrest tilting angle. Furthermore, the electromyogram results showed the new design caused a lower fatigue level of the erector spinae muscles compared to the comparison chair, and also earned a higher preference in the subjective opinion results. Conclusion: The newly designed chair in this study responds to the user"s spine curvature and maintains and enhances the lower back"s natural S-curve, and thereby relieves fatigue, promotes better posture, and helps to prevent spine deformities better than existing office chairs. There is a need to widely introduce and supply this new design. Application: The new design is applicable to office and student chairs, and is expected to improve concentration and work efficiency.
강호영 ( Ho Young Kang ),황현주 ( Hyun Ju Hwang ),박미화 ( Mi Hwa Park ),조현철 ( Hyun Cheol Jo ),박지권 ( Ji Kwon Park ),신정규 ( Jeong Kyu Shin ),이순애 ( Soon Ae Lee ),고경혁 ( Gyung Hyuck Ko ),이종학 ( Jong Hak Lee ),백원영 ( 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.11
The coexistence of carcinoma of the endometrium and ovary of female genital tract are an uncommon event, and it occurred in 5% of the patients with endometrial cancer and 10% of the patients with ovarian cancer. However, most of them are metastatic lesion from one organ and synchronous primary cancers from both organs are rare. In the present case, we experienced a case with simultaneous primary cancers from endometrium and ovary, occurring in 37-year-old woman presented with abnormal vaginal bleeding. Preoperative endometrial biopsy revealed endometrial carcinoma, and magnetic resonance imaging showed both ovarian lesion, which is suspicious of malignancy. Intraoperative and histological finding showed stage Ιb endometrioid endometrial carcinoma and stage Ⅲc mucinous adenocarcinoma of both ovary, and we present this case with a brief review of reference.