GIS와 데이터베이스를 이용한 가로수정보 관리프로그램 구축

김희년,정성관,박경훈,유주한 경북대학교 농업과학기술연구소 2008 慶北大農學誌 Vol.26 No.-

The purpose of this research is to develops street trees management program for more an effective street trees management. The principal point of this program is to relate spatial data and attribute data that is the main concept in GIS(Geographic Information System). To do this function, MapObjects which is ESRI's mapping and GIS components was used to process spatial data and Access which had been developed by MS was used to manipulate attribute data in this program. Visual Basic also was used to design and develop user interfaces and procedures, relate two sort of data , and lastly complete Application. Relational data model was adopted to design tables and their relation, Antenucci's GIS development model was selected to design and complete this program. The configuration of this application is composed of management data and reference data. The management data includes the location of street tree, a growth condition, a surrounding environment , the characters of tree, an equipments, a management records and etc. The reference data include general information about tree, blight and insects.

정신과에 대한 한 의과대학 졸업반 학생들의 태도조사

박인호,이철,한오수,김창윤,박희관 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.1

정신과에 대한 의대생들의 태도를 조사하기 위해서 정신과 임상실습을 마친 S대학교 의과대학 본과 4학년 학생들 중에서 본 연구의 설문조사에 자원응답한 70명의 자료를 분석하였다. 의대생들의 56%는 정신과가 비과학적이고 애매한 학문이라는 견해를 부정하였다. 또한 90%는 환자의 감정적 문제를 다룰 필요가 있다고 보았다. 타과의사들과 수입을 비교할 때 반수정도가 보통이라고 하였다. 83%의 의대생들은 정신과에 매력을 느끼고, 69%는 지적 성취를 할 수 있다고 보았다. 그러나, 정신과 의사의 역할과 임상심리학자나 사회사업가의 역할을 구분하는데 혼동이 있었다. 결과는 대부분의 의대생들이 정신과 의사와 직업으로서의 정신과에 대해 긍적적인 태도를 가진 것으로 나타났다. The attitudes of medical students towards psychiatry are important as they influence recruitment to psychiatry and clinical practice. In order to evaluate the attitudes of medical students towards psychiatry, the authors administered a questionnaire to 70 senior student volunteers of College of Medicine, Seoul National University. The results are summarized as follows; Psychiatrists are .not regarded by most medical students as unclear thinkers. Medical students don't think that psychiatrists abuse patients' legal rights, treat only relatively healthy patients. Most medical students affirm the importance of dealing with their patients' emotional problems. But, the roles of psychiatrists are confused with those of psychologists and social workers. Psychiatry, as a vocation, is not regarded by most medical students as unscientific, imprecise, ineffective and low in status. Most medical students don't agree that stigmatization or pressure to choose another field are common. This study showed that most senior medical students are favorable about psychiatrists and psychiatry.

IC-MS/MS를 이용한 수중의 과염소산이온 분석방법 최적화 및 한강수계내 분포조사

김현희(Hyun Hee Kim),한인섭(Ihn Sup Han),정관조(Gwan Jo Jeong),박현(Hyeon Park),한선희(Sun Hee Han),조완선(Wan Seon Cho) 大韓環境工學會 2010 대한환경공학회지 Vol.32 No.4

과염소산이온의 분석을 위해 전기전도도 검출기(CD; conductivity detector)를 연결한 이온크로마토그래피(IC; ion chromatography) 방법이 지금까지 가장 널리 사용되어 왔다. 그러나 이 방법은 시료의 조성에 영향을 받을 수 있고, 정량한계를 낮추는데 한계가 있다. 따라서, 본 연구에서는 미량의 과염소산이온 분석을 위해 이온크로마토그래피 질량분석법 (IC-MS/MS; ion chromatography mass spectrometry)을 제시하였다. IC-MS/MS를 이용한 과염소산이온의 분석방법을 적용한 결과 평균회수율 104.4±5.7%, 상대표준편차 1.9±1.3%를 얻었으며, 검출한계(MDL; method detection limit)는 0.0207±0.0099㎍/L를 얻을 수 있었다. IC-MS/MS를 한강수계 지류천과 본류에 적용시킨 결과, 최소 <0.1㎍/L에서 최고 18.30㎍/L 범위로 나타났다. 서울시 6개 아리수정수센터의 취수원수와 정수에서는 과염소산이온이 0.18~0.34㎍/L의 농도로 존재하는 것으로 나타났다. Ion chromatography (IC) coupled with conductivity detector (CD) is a common system for the determination of perchlorate in water samples. Although the IC method with CD has been widely used for the determination of trace level perchlorate ion in water, sensitivity decreases dramatically as the complexity of the matrices increases. Here we proposed the application of ion chromatography coupled with mass spectrometry (IC-MS/MS) to significantly improve selectivity of perchlorate. The mean recovery of the method was 104.4±5.7% and the relative standard deviation (RSD%) was 1.9±1.3%. The calculated method detection limit (MDL) was 0.0207±0.0099㎍/L. The concentrations of perchlorate were minimum <0.1㎍/L and maximum 18.3㎍/L in source water (Namhan, Bukhan and Han River). Hongreung showed higher concentrations (1st-14.3㎍/L, 2nd-18.3㎍/L) than the other places. And the concentrations of perchlorate were 0.18~0.34㎍/L in the samples taken from the six water treatment plants and six intake stations in Seoul.

High ATP6V1B1 expression is associated with poor prognosis and platinum-based chemotherapy resistance in epithelial ovarian cancer

( Gwan Hee Han ),( Hee Yun ),( Joon-yong Chung ),( Jae-hoon Kim ),( Hanbyoul Cho ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-

Objective: The vacuolar-ATPase subunit ATP6V1B1 belongs to the ATP6V1s family, which functions to transport hydrogen ions. The expression of ATP6V1B1 and associated clinicopathological features have been linked to various cancers; however, its role in epithelial ovarian cancer (EOC) has not been explored. In this study, we aimed to unveil the function, molecular mechanisms, and clinical significance of ATP6V1B1 in EOC. Methods: The mRNA levels of ATP6V1 subunits A, B1, and B2 in EOC tissues were determined using data from the GEPIA database and RNA sequencing. Protein levels of ATP6V1B1 were evaluated through immunohistochemistry staining of EOC, borderline, benign, and normal epithelial tissues. The association between ATP6V1B1 expression and clinicopathological features and prognosis in patients with EOC were analyzed. Furthermore, the biological role of ATP6V1B1 in ovarian cancer cell lines was also assessed. Results: RNA sequencing and public datasets analyses revealed elevated ATP6V1B1 mRNA levels in EOCs. High ATP6V1B1 protein level was also observed in EOC compared to that of borderline and benign tumors, and nonadjacent normal epithelial tissues. High ATP6V1B1 expression was associated with serous cell type, advanced FIGO stage poor tumor grade, elevated serum cancer antigen 125 levels, and platinum-resistance (p < 0.001, p < 0.001, p = 0.035, p = 0.029, p = 0.011, respectively). High expression level of ATP6V1B1 was also associated with poor overall and disease-free survival (p < 0.001). Knockdown of ATP6V1B1 decreased cancer cell proliferation and colony-forming abilities (p < 0.001) in vitro via the regulation of the G0/G1 cell cycle. Conclusion: Significance high expression of ATP6V1B1 was observed in EOC and demonstrated the prognostic significance and association with chemotherapy resistance of ATP6V1B1 in EOC, representing it as an EOC related biomarker for prognostic evaluation, chemotherapy resistance and suggesting as a potential therapeutic target for patients with EOC.

Circadian clock gene, CRY1 regulates chemoresistance with NANOG through apoptosis via STAT3 pathway in cervical cancer patients

( Gwan Hee Han ),( Hee Yun ),( Hanbyoul Cho ),( Joon-young Chung ),( Jae-hoon Kim ) 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-

Knockdown of E-cadherin expression promote cervical cancer progression through EGFR signaling pathway

( Gwan Hee Han ),( Hee Yun ),( Jae-hoon Kim ),( Hanbyoul Cho ) 대한산부인과학회 2023 대한산부인과학회 학술대회 Vol.109 No.-

Right ventricular metastatic tumor from a primary carcinoma of uterine cervix: A cause of pulmonary embolism

( Gwan Hee Han ),( Do Youn Kwon ),( Roshani Ulak ),( Kyung Do Ki ),( Jong-min Lee ),( Seon-kyung Lee ) 대한산부인과학회 2017 Obstetrics & Gynecology Science Vol.60 No.1

The presence of intracavitary cardiac metastasis from squamous cell carcinoma of the uterine cervix is extremely rare. The diagnosis is made almost exclusively postmortem. Apart from causing intracardiac obstruction, it can present as pulmonary emboli and the prognosis is extremely poor. It is important to suspect this diagnosis in patient with recurrent pulmonary emboli. Due to the rarity of this condition it is very difficult to standardize care for these patients. However, it is possible that aggressive therapy may lengthen patients` survival and quality of life. We present a case of isolated intracavitary cardiac metastasis arising from a squamous cell carcinoma of the cervix, 44-year-old woman, diagnosed as stage complaint of fatigue and dyspnea on mild exertion. The echocardiogram showed a mass in the right ventricle and suspicious pulmonary embolism. We took an aggressive therapeutic approach. The pathological examination of the resected tissue revealed metastatic squamous cell carcinoma.

원수 pH 조정에 의한 정수 수질 개선

정관조(Gwan Jo Jeong),이경우(Kyeong Woo Lee),김현희(Hyun Hee Kim),정의선(Eui Sun Jeong),박현(Hyeon Park),한선희(Sun Hee Han) 大韓環境工學會 2010 대한환경공학회지 Vol.32 No.5

상수원수의 특성 변화와 갈수기 조류 발생으로 인한 원수 pH 상승 시기에 이산화탄소(CO₂)를 주입하여 원수 pH를 조정함으로써 혼화·응집지의 응집 효율을 향상시켜 생산 정수 중의 잔류알루미늄, 탁도, 입자수 등의 농도를 낮추는 방법을 조사하고자 본 연구를 실시하였다. 원수 pH 8.0 이상이며 밤·낮의 pH 변화가 크지 않은 2월, 3월, 4월, 12월 중에 이산화탄소 주입 전·후의 정수 수질 변화를 고찰하였으며, 정수처리 공정수를 대상으로 정수 수질평가와 밀접한 관련이 있는 알루미늄, 탁도, 입자수, TOC, THMs, 2-MIB, geosmin 등의 농도 변화를 조사하였다. 조사결과, 혼화·응집지의 응집 효율 향상으로 입자수, 탁도, 알루미늄과 같은 입자성 물질과 무기물질은 감소하였으며 서울시 정수 목표수질값인 입자수 30개/mL 이하, 탁도 0.05 NTU 이하, 알루미늄 0.02 mg/L 이하의 양호한 정수 수질을 유지하기 위해서는 원수 pH 상승시기 이산화탄소를 주입하여 착수정원수 pH를 7.4 이하로 유지해야 하는 것으로 나타났다. 또한 THMs, CH, HAAs, HANs 등 소독부산 물과 이취미 유발물질인 2-MIB, geosmin 농도는 원수 pH 변화와 무관함을 알 수 있었으며, 특히 이취미 유발물질인 2-MIB, geosmin는 pH 변화보다는 원수 중의 2-MIB, geosmin 농도가 정수 중의 농도 결정에 주요한 영향을 주는 것으로 나타났다. The purpose of the study is to find ways to decrease turbidity and residual aluminum by improving the efficiency of coagulation process through controlling the pH of the source water with CO₂ when the pH increases by algal bloom or by the characteristics of the source water. Water quality parameters were monitored before and after CO₂ addition in February, March, April, and December, when the pH of the source water is over 8.0 and constant regardless of day and night. Water quality parameters closely related with evaluation of treated drinking water quality were monitored in detail, e.g. aluminum, turbidity, particle counts, TOC, THMs, 2-MIB, and geosmin. According to the results, inorganic water quality parameters such as turbidity, particle counts, and aluminum were decreased due to improved efficiency of the coagulation process. It was concluded that the pH of the water in the arrival basin must be controlled below 7.4 by adding CO₂ when the pH of the source water increasing. By controlling pH with CO₂, the water quality could be maintained within the drinking water quality goal of Seoul City (<30 particle/mL of particle count, <0.05 NTU of turbidity and <0.02mg/L of aluminum). The change of the pH could not affect the concentrations of DBP`s (e.g., THMs, CH, and HAAs) and taste/odor causing compounds (e.g., 2-MIB and geosmin). 2-MIB and geosmin were affected more by their initial concentrations in the source water.

사이버가정학습에서 학습 스타일과 교육 방법이 미치는 효과성 연구

한희섭 ( Hee Seop Han ),한선관 ( Seon Gwan Han ) 한국컴퓨터교육학회 2011 컴퓨터교육학회 논문지 Vol.14 No.1

사이버가정학습은 학습자의 학습 영역을 가정으로 확산해 가는 것이 근본 취지이지만, 학교교육과 연계되지 못하면 그 실효성이 미미하다는 것이 연구학교 교사들의 지적이었다. 본 연구에서는 사이버가정학습을 활용함에 있어서 학교교육과 연계한 블렌디드 러닝(Blended-learning) 교육방법과 학습 스타일 등 학습자의 학습 요소가 학력 향상에 미치는 영향력을 비교해보았다. 사전검사결과 사회과의 학력에 차이가 없는 두 개 학급을 선정해 1학기동안 순수한 사이버학습과 블렌디드 학습의 두 형태로 운영을 해보고, 학력 향상에 미친 요소들의 영향력을 통계적으로 검정해보았다. 그 결과 학습 방법이 가장 큰 영향력을 보여주었고, 다음으로 Kolb의 학습 스타일에서 구체적 경험을 중시하는 학습 스타일과 반성적 관찰을 중시하는 학습 스타일의 영향력이 통계적으로 유의한 차이를 보여주었다. 연구 결과 사이버가정학습의 효과적 운영을 위해 학교교육과 적극적으로 연계되어 활용되어야 하며, 학습자들의 학습 스타일에 맞추어 적합한 학습 콘텐츠가 마련되어야 함을 보여주었다. Cyber-home Learning aims to extend learning space from the classroom to real-life situations, and teachers of research schools on Cyber-home learning have indicated the importance of connection with school instruction in order to improve students` performance. The goal of this study is to evaluate the influence of the instructional method( blended-learning vs just cyber learning) and the learning styles by Kolb`s LSI on Cyber-home learning. We carried out the experiment using two similar classes in the social and math subjects for 1 semester. The results statistically shows the instructional method is the most influence on learning score and the next element is the learning styles. Therefor this study proved again Cyber-home learning is effective when connecting with school instruction and also the more various contents on learning styles could be supportive to students. In other words teacher`s role and the adaptive learning contents by learning styles are essential for Cyber-home Learning`s success.

한강수계 과염소산이온 분포

김현희 ( Hyun Hee Kim ),정관조 ( Gwan Jo Jung ),박현 ( Hyeon Park ),한선희 ( Sun Hee Han ),한인섭 ( In Sup Han ) 한국물환경학회 ( 구 한국수질보전학회 ) 2008 공동 추계학술발표회 Vol.2008 No.-