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이윤경 ( Yoon Kyung Lee ),유창영 ( Chang Young Yoo ),이귀세라 ( Guisera Lee ),박동춘 ( Dong Choon Park ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.4
A case of a 33-year-old 3 gravida, 1 para pregnant woman in the 7th week of gestation who was concurrented with dysgerminoma is presented. Measurements were made on serum lactic dehydrogenase, alpha-fetoprotein, CA-125, and pelvicmagnetic resonance imaging. The clinical stage was IA and right salpingo-oophorectomy and biopsy of the left ovary were done preserving the pregnancy. A cytological finding was non-specific. The frequency of malignant ovarian tumors associated with pregnancy and the treatment for it were discussed.
Giant congenital lymphangioma at chest wall : Case Report, Using picibanil (OK-432) Sclerotherapy
( Hui-ryeon Ju ),( Guisera Lee ),( Shin-young Kim ),( Yun-sung Jo ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Fetal lymphangioma, benign tumor, is an uncommon congenital malformation of the lymphatic system, arising from blockage of lymphatic flow. It is characterized by a thin-walled cystic dilation usually around neck and axillary region. It typically develops between late in the first trimester to early in the second trimester. Moreover, it is highly associated with chromosomal abnormalities and poor outcomes. We report a rare live-born case of giant septated, chest wall lymphangioma that underwent prenatal expectation treatment. The lymphangioma was treated of picibanil (OK-432) sclerotherapy 9 days after birth. Picibanil (OK-432) is a lyophilized mixture of group A Streptococcus pyogenes with antineoplastic activity, because of its capacity to produce a selective fibrosis of lymphangiomas. In the following 29 days, we were observed decreasing size of lymphangioma.
Case report : Uterine Torsion in Third Trimester Pregnancy
( Yong Hee Choi ),( Guisera Lee ) 대한주산의학회 2016 大韓周産醫學會雜誌 Vol.27 No.1
The preoperative diagnosis of uterine torsion is very difficult due to the rarity of this disorder and its nonspecific clinical course. A primigravida woman visited our hospital with severe abdominal pain at 34 weeks of gestation. Emergency cesarean section was carried out due to development of fetal distress and severe abdominal pain. During the cesarean section, we noticed the uterus was rotated 180 degrees and the torsion was corrected after the delivery by making a vertical incision at the posterior uterine wall. High degree of suspicion and prompt management are important factors contributing to good prognosis of uterine torsion.
자궁경부 병변의 진단에 질 확대경 및 인유두종 바이러스 검사법의 유용성
김찬주,이근우,박종섭,이귀세라,지용헌,남궁성은,김승조 대한부인종양 콜포스코피학회 1994 Journal of Gynecologic Oncology Vol.5 No.2
Specific types of HPV are currently implicated as etiologic agents of precursors and cancerous lesions of the uterine cervix. This study used the data gained from one hundred twenty five women who underwent concurrent. Papanicolaou smear, colposcopic diagnosis, and cervicovaginal lavage for HPV BNA test at Dysplasia Clinic in Kangnam St. Mary's Hospital. 38 patients had low-grade squamous intraepithelial lesions (LGSILs) and 34 had high grade squamous intraepithelial lesions (HGGILs), 24 invasive cervical cancers, and 29 normal control. Colposcopic features were prosectively recorded by Reid's colposcopic index and then correlated with histopathologic diagnosis. Using the colposcopic index, 86.4% was correlated with histopathologic findings. DNAs extracted from the cervicovaginal lavages were analyzed by polymerase chain reaction (PCR) using the HPV L1 consensus primers. HPV DNA was detected in 79 of 125 women (63.2%). Prevalences of HPV DNA in the patients with LGSIL (71.1%), HGSIL, (76.5%i) and cervix caneer (75.0%) showed no difference in statistics. Low-risk oncogenic viruses.(HPV-6/11) were present in 13.2% of patients with LGSIL, but none was detected in those with HCSIL and cervix cancer. Intermediate-risk oncogenic viruses (HPV-31/33/35) were detected in 5.3% of patients with LGSIL 8.8% in HGSIL, and none in cervix cancer. Prevalence of high-risk oncogenic type HPV 16/18 was higher in HGSIL (41.2%) and invasive cervical cancer (45.8%) than those of LGSII (15.8%) and controls (3.5 % ) (P -= 0.0(01). These data indicate that colposcopic scoring has adjunctive diagnostic role in predicting his-tology. And, HPV DNAs were found in similar incidence in the various histologic grades of cervical neoplasia. HPV-6/11 were detected only in LGSIL and HPV 31/33/35 in LGSIL and HGSIL, but not in invasive cancer. HPV-16/18 were the predominant viruses which were detected in HGSIL, and invasive cervical cancer. In canclusizn, a combination of HPV testing and colposcopic scoring would provide sensitive screening methods for cervical cancer and precanceraus lesions. And HFV typing might have prognostic value in the management of patients with HPV related cervical neoplastic lesions.
김민정,허수영,이귀세라,김사진,김은중,남궁성은 대한부인종양 콜포스코피학회 2002 Journal of Gynecologic Oncology Vol.13 No.4
목적 : 난소의 명세포암의 임상적 특징을 알아보고자 하였다. 연구 방법 : 1993년부터 2001년까지 가톨릭대학교 부속 8개 병원 산부인과에서 치료받은 23명의 난소의 명세포암 환자들을 FIGO병기, 치료, 생존율을 조사하였다. 결과 : 평균 연령은 47세(범위 36-68세)였으며, Ⅰ기 60.3% (14/23), Ⅱ기 4.4% (1/23) Ⅲ기 34.7% (8/23)이었다. 골반내 종괴의 크기는 5 ㎝에서 27 ㎝ 범위였으며, 이들 중 6명(26%)이 자궁내막증과 동반되었다. 수술을 받은 모든 환자들은 항암 치료를 받았으며, 생존한 환자의 평균 추적기관은 48.15개월(0.9-95.4개월)이었으며, 3년 생존율은 69.5%, 생존기간은 38.6개월이었다. 결론 : 난소의 명세포암은 상피암중 드문 조직학적 형태와 임상적 특징을 보인다. 여러 임상병리학적 예후 인자나 생존율, 항암 화학요법의 새로운 적용과 그 효용성 등과 관련된 결론을 확립하기 위해서는 좀 더 많은 수의 환자를 대상으로 장기적인 연구가 필요할 것으로 사료된다. Objective : The aim of this study is to evaluate the clinical characteristics of clear cell carcinoma of the ovary. Methods : Between 1993 and 2001, 23 patients with clear cell carcinoma of ovary treated in the department of obstetrics and gynecology, Catholic University Medical College were identified and reviewed retrospectively for patient profiles, International Federation of Gynecologists and Obstetricians (FIGO) disease stage, mode of therapy, and length of survival. Results : Median age was 47 years (range 36-68 years). Tumors were 60.9% (14123) stage I, 4.31% (1/23) stage II, 35.2%(8/23) stage III. All patients presented with a pelvic mass ranging in size from 5 cm to 27 cm. Of the patients with clear cell carcinoma, six (26.1 %) had associated endometriosis. all patients underwent cytoreductive surgery followed by postoperative chemotherapy. The median follow up for surviving patients is 48.15 months (range 0.9 to 95.4 months). The overall 3-year survival rates were 69.5%. The survival was 38.6 months. Conclusion : Clear cell carcinoma of the ovary is intriguing histologic type of epithelial cancer and demonstrates a clinical behavior distinctly different from that of other epithelial ovarian cancer. Predictors of survival for patients with clear cell carcinoma of the ovary needs to be further investigated by randomized large number study.
( Mi Sun Kim ),( Sun Young Nam ),( Guisera Lee ) 대한산부인과학회 2014 Obstetrics & Gynecology Science Vol.57 No.4
Most cases of double uterus with obstructed hemivagina and ipsilateral renal agenesis were diagnosed at adolescents after menarche. This is the first reported case of complete septate uterus with obstructed hemivagina and ipsilateral renal agenesis in addition to ipsilateral agenesis of fallopian tube and ovary in which the diagnosis was delayed until pregnancy. The pregnancy was uneventful in spite of intermittent vaginal spotting. During the cesarean section, the septum of the uterus was resected and about a 3-cm×3-cm window was made on the vaginal septum to allow an opening for the obstructed vaginal discharge. We followed the patient up for one and half years, and she has not had symptoms such as dysmenorrhea or abnormal vaginal bleeding.
Pseudo-Single Umbilical Artery by Spontaneous Intrauterine Umbilical Artery Thrombosis
( Minwha Baik ),( So Young Im ),( Guisera Lee ) 대한주산의학회 2019 Perinatology Vol.30 No.3
Umbilical artery thrombosis is rare event and few prenatally diagnosed cases have been reported. Antenatal diagnosis is very critical, as it is associated with high risk of perinatal motility and morbidity such as intrauterine growth restriction and intrauterine fetal death. This study presents a rare case of intrauterine umbilical artery thrombosis, diagnosed by ultrasonography, at 32 weeks and 5 days of gestation in a 34-year-old woman who had an uneventful pregnancy. Early diagnosis with color Doppler ultrasonography is critical for pregnancy outcomes when fetal movement has diminished or intrauterine growth restriction is diagnosed, even though two umbilical artery already been confirmed on the first or the second-trimester ultrasonography scans.