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Slowly Progressing Thrombotic Microangiopathy during Two Years of Treatment with Sunitinib
( Min Young Kim ),( Hee Jung Choi ),( Yoon Jung Kim ),( Na Ree Kang ),( Hye Ryoun Jang ),( Ghee Young Kwon ),( Woo Seong Huh ),( Young Suk Park ),( Yoon Goo Kim ),( Dae Joong Kim ),( Ha Young Oh ),( J 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.5
A 75-year-old man with mild renal impairment was started on sunitinib for a metastatic gastrointestinal stromal tumor. After 7 months of this therapy, proteinuria became aggravated. Serum creatinine concentration was increased from 1.34 to 2.57 mg/dL 24 months after sunitinib administration. Hematologic features of thrombotic microangiopathy (TMA) were absent. Renal histology revealed endothelial swelling and plasmatic insudation of the glomeruli. Proteinuria and renal function improved after discontinuation of sunitinib. Our experience suggests that TMA associated with sunitinib can be diverse in onset and severity, and that the hematologic features of TMA may be absent.
Park, Sanghui,Kang, So Young,Kwon, Ghee Young,Kwon, Ji Eun,Kim, Sang Kyum,Kim, Ji Yeon,Kim, Chul Hwan,Kim, Hyun-Jung,Moon, Kyung Chul,Pyo, Ju Yeon,Park, Won Young,Park, Eun Su,Sung, Ji-Youn,Sung, Sun College of American Pathologists; 1999 2017 ARCHIVES OF PATHOLOGY AND LABORATORY MEDICINE Vol.141 No.5
고혈압 환자의 건강 문해력과 질환관련 지식 및 치료지시 이행에 관한 연구
권명순(Kwon, Myung Soon),노기영(Noh, Ghee-Young),장지혜(Jang, Ji Hye) 한국보건간호학회 2013 韓國保健看護學會誌 Vol.27 No.1
Purpose: To survey relationships between health literacy, disease-related knowledge and compliance to medical recommendations in patients with hypertension. Methods: The subjects were 315 patients conveniently selected from public health centers in Gangwon province. Data were collected through a questionnaire (from January 10, 2013 to February 10, 2013) and analyzed by descriptive statistics, t-test, ANOVA, Duncan test and Pearson"s correlation coefficient using the PASW statistics 18.0 program. Results: There were significant differences in health literacy according to age, marital status, monthly family income and education. In regard to disease-related knowledge, there were significant differences according to gender, marital status and monthly family income. There were positive correlations between health literacy and disease-related knowledge (r = .39, p = <.001), disease-related knowledge and compliance to medical recommendations (r = .28, p = <.001). However, there was no correlation between health literacy and compliance to medical recommendations. Conclusion: Health literacy and disease-related knowledge have a significantly positive correlation. Further studies are needed to confirm the effects of health literacy on chronic diseases.
권명순(Kwon, Myung Soon),노기영(Noh, Ghee-Young),장지혜(Jang, Ji Hye) 한국보건간호학회 2013 韓國保健看護學會誌 Vol.27 No.3
Purpose: The purpose of this study was to compare the images, knowledge, and stereotypes plus perceptions about the elderly between students in nursing class and those in other classes and to determine the correlation among variables. Methods: The subjects of this study were 400 students, 200 from nursing class and 200 from other classes(premedical students were excluded) from one university. Result: Images the elderly of all participants showed an average score of 2.96(±0.376), total average score of knowledge about the elderly was 16.22(±2.356), and average score for stereotypes plus perception was 2.92(±0.394). Comparison between students in nursing class and those in the other classes showed that students in the nursing class had deeper knowledge regarding physical and physiological fields of the elderly, however they had comparatively negative cognition in the images and stereotypes plus perceptions about the elderly. In addition interest in the elderly and volunteer experiences were significantly affected by the images and stereotypes plus perceptions. Images, knowledge, and stereotypes plus perceptions about the elderly showed significant positive correlation. Conclusion: In development of curriculum related to the elderly in nursing class, development of specific and diverse approaches that will raise positive awareness of the elderly is necessary.