[논문]다른 온도로 소성한 왕겨를 콘크리트 흔화재로 사용한 콘크리트의 강도특성에 관한 연구

신상엽,정의창,정유진,박문석,백계승,최세윤,김영수 釜山大學校生産技術硏究所 2007 生産技術硏究所論文集 Vol.66 No.-

본 논문은 다른온도로 소성한 왕겨를 콘크리트 흔화재로 사용한 콘크리트의 강도특성을 알아보기 위한 것으로 물결합재비를 35% 로 고정하고 왕겨의 혼입률을 각기 달리하여 소성온도에 따른 압축강도 특성과 왕겨의 혼입률에 따른 강도특성을 평가하였다. 실험결과 왕겨가 혼화재로서 성능을 발휘하는 최저 온도가 600℃인 것으로 나타났으며, 700℃로 소성한 경우 가장 우수한 강도 값을 나타내었다. 또한 혼입률별 압축강도 특성에서는 혼입률 10% 에서 가장 우수한 강도발현을 나타내었다.

대퇴동맥을 통한 경피적 관동맥 중재시술 환자의 천자부위 지혈을 위한 Angioseal^(�) 사용과 고식적 용수 압박법의 비교 : 전향적 연구

김용훈,권현철,김필호,안석진,유철웅,최진호,이상철,김준수,김덕경,전은석,이상훈,홍경표,박정의,서정돈 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 경피적 관동맥 중재술은 최근 양적 및 질적으로 급격한 발전을 보였지만 시술 시 천자부위의 혈관 합병증은 아직 해결해야 할 문제점이다. 저자들은 대퇴동맥을 통한 경피적 관동맥 중재술을 환자에게 천자부위 지혈을 위한 혈관폐쇄기구인 안지오실의 안전성과 유용성을 고식적인 용수 압박법과 비교 연구하고자 하였다. 방법 : 2002년 4월부터 2003년 5월 사이에 삼성서울병원 심장혈관센터에서 대퇴동맥을 통한 경피적 관동맥 중재술을 성공적으로 시행한 200명의 환자(안지오실 사용군: A군, 100명, 고식적 용수압박법 사용군 B군, 100명)를 대상으로 시술 후 주요 합병증 및 경한 합병증, 지혈 후 환자가 자리에 앉기까지의 시간, 보행개시 가능시간, 총 재원 기간과 시술 1주 후의 합병증을 전향적으로 조사하여 비교 연구하였다. 결론 : 두 군에서 연령, 성별, 기저질환, 심혈관 질환의 위험요소, 시술의 종류, 시술 중 사용한 헤파린의 양, clopidogrel의 양, ticlopidine의 양, 지혈 시 수축기와 확장기혈압, ACT (activated clotting time)는 차이가 없었다. A군이 B군에 비해 시술 후 자리에 앉기까지의 시간 (A군: 4.3±0.3시간, B군: 13.7±0.8시간, p=0.004) 및 보행개시까지의 시간(A군: 6.8±0.5시간, B군: 18.8±2.1시간, p=0.013)이 유의하게 짧았다. 시술 후 주요 합병증은 두군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 A군에서 유의하게 적었다(A군: 28명, B군: 19명, p=0.003). 반상출혈의 경우는 A군에서 유의하게 낮았지만(A군: 3명, B군: 12명, p=0.01), 혈종, 출혈의 발생은 두군간에 차이가 없었다. 총 재원기간에는 두 군간에 차이가 없었다(p=0.239). 시술 1주 후 경과관찰에서 주요합병증은 역시 두 군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 두 군에서 차이가 없었다(A군: 15명, B군: 13명 p=0.418), 반상출혈의 빈도는 차이가 없었지만 혈종의 발생은 A군에서 더 낮았다(A군: 2명, B군:6명, p=0.004). 두 군 모두에서 출혈은 발생하지 않았다. 결론 : 대퇴동맥을 통한 경피적 관동맥 중재술을 시행한 환자에서 안지오실의 사용은 고식적 용수 압박법에 비해 환자의 침상 안정시간을 줄여 조기 활동개시가 가능하게 하였으며 국소합병증의 위험도를 일부 낮추어, 시술에 따른 환자의 불편을 현저하게 감소시킬 수 있다고 할 수 있을 것으로 기대된다. Background : Although the number and the quality of percutaneous coronary intervention have been recently increased dramatically, the vascular complication at puncture site is still the major cause of patients' morbidity. We evaluated the safety and efficacy of newly of newly-developed collagen-based arterial closure device, Angioseal after transfemoral percuatenous coronary intervention. Methods : This study was designed as a prospective single center non-randomized comparative study. A total 200 patients undergoing transfemoral percutaneous coronary intervention were enrolled between April 2002 and May 2003. They were divided into two groups; Angioseal group (group A, n=100) and manual compression group (group B, n=100). The baseline clinical and angiographic characteristics were reviewed. The time to sit up, the time to ambulation, the duration of hospital stay, major and minor vascular puncture site complications were monitored. The patients were followed-up for 1 week after procedure by telephone. Results : The baseline clinical characteriwtics, clinical diagnosis, cardiocascular risk factors, typesof procedure, doses and numbers of anticoagulants were similar between two groups. The blood pressure and activated clotting time were also similar. The time to sit up (group A: 4.3±0.3 hours, group B: 13.7±0.8 hours, p=0.004) and the time to ambulation (group A: 6.8±0.5 hours, group B: 18.8±2.1 hours, p=0.013) were shorter in group A. No major vascular complications were noted. The incidence of hematoma and bleeding were not significantly different between two groups. The incidence of ecchymosis, however, was significantly lower in group A (group A:12%, group B: 3%, p=0.001) The duration of gospital stay was similar between groups. During 7 days of follow-up period incidence of hematoma was significantly lower in group A (p=0.004). Although the incidence of ecchymosis was not significantly different between two groups. Conclusion : The angioseal may be associated with earlier ambulation and less patients' morbidity with low incidence of local complication rate compared to manual compression after transfemoral percutaneous coronary intervention.

Mid-term angiographic benefit of sirolimus-eluting stents compared with paclitaxel-eluting stents in patients with acute myocardial infarction

Choi, Cheol Ung,Rha, Seung-Woon,Chen, Kang-Yin,Jin, Zhe,Minami, Yoshiyasu,Shin, Seung Yong,Na, Jin Oh,Suh, Soon Yong,Lim, Hong Euy,Kim, Jin Won,Kim, Eung Ju,Park, Chang Gyu,Seo, Hong Seog,Oh, Dong Joo Elsevier 2009 Journal of cardiology Vol.54 No.1

<P><B>Summary</B></P><P><B>Background</B></P><P>We compared angiographic and clinical outcomes among different drug-eluting stents (DESs) in Korean acute myocardial infarction (AMI) patients.</P><P><B>Methods</B></P><P>A total of 109 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) with either sirolimus-eluting (SES, <I>n</I>=56 pts) or paclitaxel-eluting stents (PES, <I>n</I>=53 pts) were enrolled from August 2004 to December 2006. The angiographic outcomes at 6 months and clinical outcomes at 1 year were compared between the two groups.</P><P><B>Results</B></P><P>Baseline clinical and procedural characteristics were similar between the two groups. At 6 months, the rate of binary restenosis was 17.0% in the PES group compared with 3.6% in the SES group (<I>p</I>=0.026). Percent restenosis was 24.9±28.6% in the PES group compared with 11.2±17.6% in the SES group (<I>p</I>=0.004). Length of restenosis segment was 3.21±9.02mm in the PES group compared with 0.89±2.38mm in the SES group (<I>p</I>=0.048). Late loss was 0.73±0.89mm in the PES group compared with 0.28±0.37mm in the SES group (<I>p</I>=0.001). However, there were no differences in clinical outcomes at 1 year including mortality, myocardial infarction, repeat PCI, and major cardiac adverse events between two groups.</P><P><B>Conclusion</B></P><P>SES implantation in patients with AMI was associated with reduction in angiographic restenosis at 6 months compared with PES, however, these angiographic benefits were not translated into better clinical outcomes in real world clinical practice.</P>

Protein Wasting in Patients Undergoing Maintenance Hemodialysis

Euy - Jin Choi 대한신장학회 1992 추계학술대회 초록집 Vol.1992 No.-

Protein Wasting in Patients Undergoing Maintenance Hemodialysis

Choi, Euy-Jin 대한신장학회 1992 대한신장학회잡지 Vol.11 No.부록6

The Changes of Serum and Urinary Excretion of β₂-Microglobulin after Renal Transplantation and in Several Renal Disorders

Choi, Euy Jin,Min, Byong Sok CATHOLIC MEDICAL CENTER 1980 Bulletin of the Clinical Research Institute Vol.8 No.1

In order to elucidate the clinical significance of β_2-m in postrenal trans plants, the β_2-m of serum and urine were measured on 20 cases of postrenal transplants (1 week postoperatively), 10 cases of kidney donor, 12 cases of diabetes mellitus, and 12 cases of primary nephrotic syndrome, 10 cases of chronic renal failure due to glomerulonephritis. In the normal group, the serum β_2-m level was 1.6±0.8 ㎍/ml, and urinary excretion of β_2-m was 0.13±0.10 mg/24h. In the diabetic group, the serum β_2-m was similar to that of the normal group, but urinary excretion rate of β_2-m, clearance of β_2-m and C β_2-m /Ccr ratio were higher than those of the normal group. In the nephrotic group, the serum β_2-m was similar to that of the normal, whereas urinary excretion of β_2-m, clearance of β_2-m and C β_2-m/Ccr ratio were higher than those of the normal group, but lower than those of diabetic group. In the chronic renal failure group, the serum β_2-m was high and urinary excretion of β_2-m was increased markedly. In the transplants group, serum β_2-m level was slightly increased, but excretion rate and clearance of β_2-m, C β_2-m/Ccr were markedly increased, being the most prominent among the study groups. The changes suggest tubular dysfunction and accelerated turnover of β_2-m in renal transplant recipients.

Bare-metal stents versus drug-eluting stents in large (≥3.5mm) single coronary artery: Angiographic and clinical outcomes at 6 months

Na, Jin Oh,Kim, Jin Won,Choi, Cheol Ung,Choi, Un Jung,Shin, Seung Yong,Lim, Hong Euy,Kim, Eung Ju,Rha, Seung-Woon,Park, Chang Gyu,Seo, Hong Seog,Oh, Dong Joo Elsevier 2009 Journal of cardiology Vol.54 No.1

<P><B>Summary</B></P><P><B>Background</B></P><P>Although drug-eluting stents (DES) have been shown to dramatically reduce restenosis and improve the rate of event-free survival in large randomized trials, the benefit of DES appears to be limited to restenosis. In large arteries, it is not clear which type of stent is more superior in angiographic and clinical outcomes between DES and bare-metal stents (BMS). We compared the angiographic and clinical outcomes of DES versus BMS in large arteries (≥3.5mm).</P><P><B>Method</B></P><P>Two hundred and forty patients from March 2002 to March 2007 received stents; 196 patients were treated with DES (44.9% sirolimus-eluting stents; 43.9% paclitaxel-eluting stents; 11.2% zotarolimus-eluting stents) and 44 with cobalt–chromium BMS for single de novo lesions in a large vessel. All subjects received aspirin, clopidogrel, and/or cilostazol as the standard antiplatelet regimen. The angiographic and clinical outcomes were evaluated at 6 months.</P><P><B>Results</B></P><P>For the baseline characteristics, there were no significant differences between the DES and BMS groups. In addition, for the initially implanted stent there was no difference in the length, stent diameter, and lesion site between the two groups. After 6 months, the follow-up angiogram showed that in-stent diameter restenosis and late loss was more common with BMS than DES (39±21% vs. 19±17%, <I>p</I>=0.007; 1.44±0.83mm vs. 0.62±0.58mm, <I>p</I>=0.009, respectively). However, the target-lesion revascularization/target-vessel revascularization, and total major adverse cardiac events showed no significant differences between the groups (5.3% vs. 3.6%, <I>p</I>=0.62; 5.3% vs. 4.6%, <I>p</I>=0.86, respectively).</P><P><B>Conclusion</B></P><P>The DES and cobalt–chromium BMS placed in large coronary arteries showed equally favorable 6-month clinical outcomes, although the 6-month angiographic results appeared more favorable in the DES group than in the BMS group.</P>

Impact of Cigarette Smoking: a 3-Year Clinical Outcome of Vasospastic Angina Patients

Byoung Geol Choi,Seung-Woon Rha,Taeshik Park,Se Yeon Choi,Jae Kyeong Byun,Min Suk Shim,Shaopeng Xu,Hu Li,Sang-Ho Park,Ji Young Park,Woong Gil Choi,Yun-Hyeong Cho,이선기,Jin Oh Na,Cheol Ung Choi,Hong Euy 대한심장학회 2016 Korean Circulation Journal Vol.46 No.5

However, it is largely unknown whether smoking adds to any long-term clinical risk in VSA patients. Subjects and Methods: A total of 2797 patients without significant CAD underwent acetylcholine (Ach) provocation test between November 2004 and October 2010. Patients were divided into three groups, based on the presence of coronary artery spasm (CAS) and smoking habits (non-CAS group: n=1188, non-smoking CAS group: n=1214, smoking CAS group: n=395). All CAS patients were prescribed with anti-anginal medications for at least 6 months. The incidence of major clinical outcomes and recurrent angina of these groups were compared up to 3 years. Results: There were considerable differences in the baseline clinical and angiographic characteristics among the three groups, but there was no difference in the endpoints among the three groups (including individual and composite hard endpoints) such as death, myocardial infarction, de novo percutaneous coronary intervention, cerebrovascular accident, and major adverse cardiac events. However, there was a higher incidence of recurrent angina in both the non-smoking CAS group and smoking CAS group, as compared to the nonCAS group. In multivariable adjusted Cox-proportional hazards regression analysis, smoking CAS group exhibited a higher incidence of recurrent angina compared with the non-CAS group (hazard ratio [HR]; 2.46, 95% confidence interval [CI]; 1.46-4.14, p=0.001) and nonsmoking CAS group (HR; 1.76, 95% CI; 1.08-2.87, p=0.021). Conclusion: Cigarette smoking CAS group exhibited higher incidence of recurrent angina during the 3-year clinical follow-up compared with both the non-CAS group and non-smoking CAS group. Quitting of smoking, paired with intensive medical therapy and close clinical follow-up, can help to prevent recurrent angina.

The impact of myocardial bridge on coronary artery spasm and long-term clinical outcomes in patients without significant atherosclerotic stenosis

Nam, Purumeh,Choi, Byoung Geol,Choi, Se Yeon,Byun, Jae Kyeong,Mashaly, Ahmed,Park, Yoonjee,Jang, Won Young,Kim, Woohyeun,Choi, Jah Yeon,Park, Eun Jin,Na, Jin Oh,Choi, Cheol Ung,Lim, Hong Euy,Kim, Eung Elsevier 2018 Atherosclerosis Vol.270 No.-

<P><B>Abstract</B></P> <P><B>Background and aims</B></P> <P>Myocardial bridge (MB) and coronary artery spasm (CAS) can induce a sustained chest pain, acute coronary syndrome (ACS) and even sudden cardiac death. The aim of this study is to evaluate the relationship between MB and CAS and its impact on long-term clinical outcomes.</P> <P><B>Methods</B></P> <P>A total of 812 patients with MB without significant coronary artery disease (CAD), who underwent acetylcholine (ACH) provocation test, were enrolled. Significant CAS was defined as ≥70% temporary narrowing by ACH test, and MB was defined as the characteristic phasic systolic compression of the coronary artery with a decrease of more than 30% in diameter on the angiogram after intracoronary nitroglycerin infusion. To adjust baseline confounders, logistic regression analysis was performed. The primary endpoint was incidence of CAS, and secondary endpoints were major adverse cardiac events (MACE) and recurrent angina requiring repeat coronary angiography (CAG) at 5 years.</P> <P><B>Results</B></P> <P>MB is closely implicated in a high incidence of CAS, spontaneous spasm, ischemic ECG change and chest pain during ACH provocation test. In addition, MB of various severity and reference vessel size was substantially implicated in CAS incidence, and severe MB was a strong risk factor of CAS. MB patients with CAS were shown to have a higher rate of recurrent angina compared with MB patients without CAS, up to a 5-year follow-up. However, there were no differences regarding the incidence of MACE.</P> <P><B>Conclusions</B></P> <P>Severe MB was associated with high incidence of CAS, and MB patients with CAS were likely to have a higher incidence of recurrent angina. Intensive medical therapy and close clinical follow-up are needed for better clinical outcomes in MB patients with CAS.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The aim of this study is to evaluate the relationship between myocardial bridge (MB) and coronary artery spasm (CAS). </LI> <LI> A total of 812 patients with MB without significant coronary artery disease who underwent acetylcholine test were enrolled. </LI> <LI> Severe MB was associated with high incidence of CAS, and MB patients with CAS had a higher incidence of recurrent angina. </LI> </UL> </P>

Impact of alcohol drinking on acetylcholine-induced coronary artery spasm in Korean populations

Sohn, Sung Min,Choi, Byoung Geol,Choi, Se Yeon,Byun, Jae Kyeong,Mashaly, Ahmed,Park, Yoonjee,Jang, Won Young,Kim, Woohyeun,Choi, Jah Yeon,Park, Eun Jin,Na, Jin Oh,Choi, Cheol Ung,Lim, Hong Euy,Kim, Eu Elsevier 2018 Atherosclerosis Vol.268 No.-

<P><B>Abstracts</B></P> <P><B>Background and aims</B></P> <P>Generally, immoderate alcohol consumption is associated with variant angina and accepted as one of the risk factors for coronary artery spasm (CAS), but evidence is lacking in this regard. The aim of this study is to evaluate the impact of alcohol consumption and drinking pattern on CAS by acetylcholine (ACH) provocation test and long-term clinical outcomes.</P> <P><B>Methods</B></P> <P>A total of 5491 patients with typical or atypical chest pain, without significant coronary artery disease, who underwent intracoronary ACH provocation test, were enrolled prospectively, and retrospectively analyzed in this study. They were divided into two groups according to their alcohol drinking status; the current alcohol (CA) drinking group (n = 1792), and non-CA group (n = 3699). To adjust for potential confounders, a propensity score matching (PSM) analysis was performed. The primary endpoint was incidence of CAS, and secondary endpoints were major adverse cardiac events (MACE) and recurrent angina requiring repeat coronary angiography (CAG) at 5 years.</P> <P><B>Results</B></P> <P>After PSM analysis, alcohol consumption was a strong risk factor for CAS. Furthermore, excessive alcohol consumption was correlated with a higher risk for CAS. As compared with the non-CA group, the CA group showed worse angiographic and clinical findings, including higher incidence of CAS (58% <I>vs.</I> 62%, <I>p</I> = 0.016), spontaneous spasm (17% <I>vs.</I> 22%, <I>p</I> = 0.004), multi-vessel spasm (31% <I>vs.</I> 37%, <I>p</I> = 0.009), proximal epicardial spasm (39% <I>vs.</I> 46%, <I>p</I> = 0.002), ischemic electrocardiography changes such as T-inversion (0.4% <I>vs.</I> 1.2%, <I>p</I> < 0.001) and chest pain (42% <I>vs.</I> 46%, <I>p</I> = 0.047) during ACH provocation test. However, the status and pattern of alcohol drinking had no influence on long-term clinical outcomes such as MACE or recurrent angina.</P> <P><B>Conclusions</B></P> <P>Alcohol consumption is a strong risk factor for CAS, and excessive alcohol consumption was correlated with a higher risk for CAS. Further well-designed studies are needed to confirm the results.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The aim of study is to evaluate the impact of alcohol consumption on coronary spasm (CAS) and long-term clinical outcomes. </LI> <LI> Alcohol consumption is a strong risk factor for CAS. </LI> <LI> Furthermore, excessive alcohol consumption was correlated with a higher risk for CAS. </LI> </UL> </P>