상부 조기 위암 환자의 복강경하 상부 위절제술 3례 경험

조규석,김형철,박경규,이문수,송옥평,임철완,신웅진,주종우,유기원 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Background : The reported incidence of early gastric cancer located in the upper portion of the stomach has been increasing with the recent advances in its diagnosis and screening. Recently, we have successfully performed laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without pyloroplasty on three patients with early gastric carcinoma localized to the upper third of the stomach. We describe our modification of this procedure in this report. Method : After creating an surgical pneumoperitoneum, the stomach was mobilized using laparoscopic coagulating shears. Upper half of the greater curvature and three-quarters of the lesser curvature were then dissected along with regoinal D2 lymphadenectomy. This was followed by a 5 cm, longitudinal mini-laparotomy in the upper abdomen, and the construction of the exteriorized stomach with a gastric tube measuring 20 cm long and 4 cm wide. Reconstruction with an esophagogastrostomy was performed using a circular stapler. Result : No post-operative morbidity or mortality was observed in this small series of patients. The average operative time was 250 minutes (range 220-300 minutes), and the average blood loss was 150 ml (range 90-180 ml). The mean number of lymph nodes harvested during these laparoscopic proximal gastrectomies was 24 nodes (range 22-25 lymph nodes). The average postoperative hospital stays was 7.5 days (range 7-8 days). Conclusion : Our technique of laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without phloroplasty offers a minimally invasive technique with the potential of impoving the post-operative quality of life patients with an early-stage proximal gastric cancer.

진자검사와 동적근전도를 이용한 경직 평가

이은우,조강희,김봉옥 大韓再活醫學會 1999 Annals of Rehabilitation Medicine Vol.23 No.3

시설 청소년과 일반 청소년의 진로의식성숙, 불안 및 내외통제성간의 관계

조옥귀,변은진 경남대학교 경남지역문제연구원 2003 경남지역연구 Vol.9 No.-

폐광지역 토양과 농작물 중의 중금속 오염도 조사

방은옥,정용준,조영채 忠南大學校 環境問題硏究所 2002 環境硏究 Vol.20 No.-

This study was conducted to investigate the concentration of the heavy metals among the soils and crops, and the difference compared with the unpolluted area from the radius distance from the ruined mine. Gubong Mind in Cheongyang-Gun, Chungnam-Do was selected as the ruined mine, which the Taechi-Myon district was selected ad the unpolluted control area. Pepper, welch onion, cabbage, radish and their soils were collected at the mine and unpolluted area, respectively. The concentration of heavy metals(Pb, Cd, Cu, Zn and As) were measured by ICP. In the soil sample, the average concentrations of all the heavy metals were significantly increased in the min area compared with those of the unpolluted area and significantly differed from the radius distance from ruined mine. In the crop sample, the average concentration of Pb, Zn and As metals were significantly increased in the mine area compared with those of the unpolluted area and all the heavy metals were significantly differed from the radius distance from ruined mine. There was a significant negative correlation among the soils from the radius distance from ruined mine and among the crops in the concentrations of all the heavy metals. There was a significant positive correlation between soils and crops in concentration of Pb, Cd, Zn and As metals. The results indicate the concentrations of heavy metals among the soils and crops at the ruined mine were saturated more than the unpolluted and the soil metals had spread to the crops. Consequently, we cannot leave the matter unsettled and its utilization must be studied to lower the contamination degree.

토란병 제조 전처리 과정 중의 토란의 이화학적 특성에 관한 연구

김은경,정은경,이현옥,염초애 동아시아식생활학회 1995 동아시아식생활학회지 Vol.5 No.3

Studies were carried out to investigate physicochemical properties of taro during the pretreatment process of making Toranbyung. Seventeen kinds of amino acids were found in taro. Aspartic acid and glutamic acid were most plentiful among those amino acids. Essential amino acids were about 42.7% of the total amino acids. Sulfur containing amino acids, methionine and cystine were about 2.7%. The amylograph indicated that the initial temperature triggering gelatinization of both rice flour mixed with taro and glutinous rice flour mixed with taro increased as the amount of taro increased. But the maximum viscosity of rice flour mixed with taro did not increase as the amount of taro increased while the maximum viscosity of glutinous rice flour mixed with taro increased as the amount of taro increased. And the peak temperature of both rice flour mixed with taro and glutinous rice flour mixed with taro increased as the amount of taro increased. The alkali degree of insoluble ash was higher than that of soluble ash. Glutinous rice dough had more total sugar than rice dough. Yellowness of rice dough was higher than that of glutinous rice dough.

토란병의 질감적 특성에 관한 연구

김은경,정은경,이현옥,염초애 동아시아식생활학회 1995 동아시아식생활학회지 Vol.5 No.3

The objective of this study was to evaluate Toranbyung, according as the ingredients of Toranbyung were changed in various phases: firstly, mixing of taro with either rice flour or glutinous rice flour, and secondly, the amount of taro to be mixed with either rice flour or glutinous rice flour. The results were as follows; According to the sensory evaluation, Toranbyung made from glutinous rice flour and 40% taro ingredients met with the most favorable responses except flavor. In the case of Toranbyung made from rice flour, those made with 50% taro ingredients were most favored in taste, flavor, moisture, color, consistency and texture. With respect to the rheological properties of Toranbyung, hardness, gumminess and springiness of Toranbyung made from glutinous rice flour were better. As the amount of taro increased, Toranbyung made from glutinous rice flour decreased in springiness, hardness, gumminess, and chewiness. As a result, Toranbyung made from glutinous rice flour and 40% taro ingredients and Toranbyung made from rice flour and 50% taro ingredients received the most favorable sensory evaluation.

한국판 임상가용 아동 및 청소년을 위한 외상후 스트레스장애 척도의 신뢰도 및 타당도 연구

구정일,김태형,은헌정,최말례,이선미,조수진,송옥선,김형욱 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6

Objectives : This present study was conducted to explore the reliability and the validity of Clinician Administered PTSD Scale for Children and Adolescents Korean version (CAPS-CA) Mcthods : The Subjects were children and adolescents (8-13yrs) from different places: a certain elementary school, three orphanages, a general hospital, and two neuropsychiathc local clinics. Only subjects who experienced a catastrophic traumatic event were tested by CAPS-CA, CDI, RCMAS, and TSC. Rcsults : The range of correlations between item-criterion were .67-.84. The coefficients of internal consistency were .87. and test-retest reliability was .90, were all the coefficients in the proper range. Inter-correlations of CAPS-CA, CDI, RCMAS, and TSC scale showed significant correlation. TSC showed the highest correlation coefficient. CAPS-CA can be a useful clinician-administered diagnostic instrument for children and adolescents PTSD symptoms. Conclusion : The reliability and the validity of CAPS-CA were confirmed. CAPS-CA could be applied for diagnostic purposes of PTSD in children and adolescents.

정신분열병과 Neuregulin 1 유전자의 연합연구

박동연,이유상,조은영,조승희,장용이,전현옥,장수연,윤세창,김종원,홍경수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The authors recently found a suggestive evidence of linkage of chromosome 8p21-12 to schizophrenia in Korean multiplex families. Neuregutin 1 (NRGI) was identified in this locus as a positional and functional candidate gene for Schizo-phrenia, through several independent studies with European and Chinese populations. The purpose of this study is to determine whether NRGl is associated with schizophrenia in Korean population. Methods : Three SNPs (SNP8NRG221533, SNP8NRG241930, SNP8NRG243177) and two microsatellites markers (478B14-848,420M9-1395) located at the 5' end of NRGI were genotyped for 242 unrelated schizophrenia patients and the same num-ber of normal controls. Genetic association was tested by χ²-test (df=1). Not only for the whole patients group but also for asubgroup of patients with auditory hallucination. This subtype showed stronger linkage with chromosome 8p12 in the prior study of the authors with multiplex families. Results : G allele of SNP8NRG241930 was significantly in excess in the subgroup of patients with auditory hallucination compared to the control group (p=0.03, 0R=1.76). We also found that 3 SNPs haplotype TTC (p=0.04, 0R=0.58) and five markers haplotype TTC53 (p=0.01,0R=0.49) were associated with schziophrenia with a protective effect. Three SNPs haplotype CGT which is a part of the at-risk haplotype of the Icelandic schizophrenia families was found in excess in the patients group but no significant association was observed. Conclusion : NRGI might either play a mle in the predisposition to schizophrenia or be in linkage disequilibrium with a causal locus of this illness.

뇌실주위 백질연화증 발생 위험인자

이동환,서은숙,이우령,조명환,박재옥 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

The twenty newborn infants with periventricular leukomalacia(PVL) who were admitted to the neonatal intensive care unit of SoonChunHyang University Hospital from May 1, 1993 to July 30, 1997, were investigated for risk factors. Control group were the age matched 20 neonates who were admitted at the same time of study period. The results were as follows: 1) Mean gestational age was 31 week and mean birth weight 1665gm. 2) PVL's were located in the parietal region in 10 cases, fronto-occipital in 7 cases and parieto-occipital region in 3 cases. 3) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizong enterocolitis and ventilator apply were the most significant contributing factor(P<0.05). 4) In a follow-up ultrasonograptic findings, 11 among 14 neonates with localized PVL were normalized whereas, all of 6 extensive PVL had the sequale of ventriculomegaly or cerebral atrophy. 5) In a follow-up neurologic examination, the poorer sequale including spastic diplegia or quadriplegia was associated with the larger, the more extensive PVL.

미나리과 산채의 아질산염 소거능

노광석,양미옥,조은자 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.1

The nitrite scavenging effect of three kinds of edible wild plants belong to Umbelliferaeceae family was investigated. The contents of crude protein, crude lipid and β-carotene of the plants were in the range of 22.99∼31.00%, 3.51∼5.08% and 5.40∼19.81 ㎎%, respectively. The content of ascorbic acid was very low and selenium was not detected in any samples. The contents of linoleic acid and linolenic acid were 66.46∼77.44%. The content of total phenol was 875.77 ㎎% in Ledebouriella seseloides WOLFF, which was the highest among the samples. The methanol fraction of the plant extract showed higher nitrite scavenging effect than the water fraction. The nitrite scavenging effects of the samples were the highest at pH 1.2 and lowest at pH 6.0, suggesting that it's pH dependent. Nitrite scavenging effect of methnol-soluble fractions obtained from Ledebouriella seseloides WOLFF was 95.3% at pH 1.2, which was the greatest among tested samples. There was a high correlation between the nitrite scavenging effect and the total phenol content.