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      • 위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

        김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

      • KCI등재

        2004년 7월 봇돌바다의 썰물, 전류 및 밀물시 수온과 염분 분포

        최용규,조은섭,이용화,이영식 한국환경과학회 2005 한국환경과학회지 Vol.14 No.2

        Based on the observation on 20, 23 and 26 July 2004, the distributions of temperature, salinity and stratification was investigated in relation to ebb, turn of tide and flood. The results are as follows: 1) The high temperature and low saline water with 23.5-24.0℃ and 32.4~33.0psu existed at Naro Island. 2) The cold surface water below 21.00 and 33.0~33.4psu appeared in the area near Gae Island and Geumo Island. 3) The cold and saline water, below 24.0℃ at the surface and 17.0℃ near the bottom, 32.8~33.8psu at the surface and 33.8~34.0psu near the bottom, existed in Sori Island. These waters were more saline compared to the South Sea Coastal Water with about 31.8psu. This suggests that the oceanic saline water intruded into the Bottol Bada through the area near Sori Island. The stratification appeared during all the observation periods due to a high solar radiation of 22MJ/m², and a weak wind speed of 2.9m/s on the average while the mean speed of wind in July is around 3.9 m/s. It qualitatively suggested that the stratification was maintained during the observation periods because of a high solar radiation, a weak wind speed and intrusion of saline oceanic water.

      • KCI등재

        2004년 7월 봇돌바다의 영양염과 Chlorophyll-a의 단기 변동

        최용규,조은섭,권기영,이용화,이영식 한국환경과학회 2005 한국환경과학회지 Vol.14 No.4

        In order to study the temporal variations of nutrients and chlorophyll-a in the Bottol Bada, three field observations were carried out on 20, 23 and 26 July, 2004. The low N:P values exhibit nitrogen deficiency during the periods of observation. This result is not representative of typical summer environment in the southern coast of Korea. The possible mechanisms are as follows: 1) The freshwater inflow was not sufficient for the supply of nitrogen because the total precipitation was 11.9 mm in July, 2004. This amount is no more than 5% in normal precipitation in July. 2) There was an inflow of oceanic water under the subsurface into the Bottol Bada. Even though the oceanic water comprises more nutrients, it produces the stratification between the surface and the subsurface water and seems to prevent the supply of nutrinets to the surface layer. 3) The high chlorophyll-a concentration of 1.2 ㎍/L was shown near the narrow channel between Gae-do and Geumo-do. This seems to be resulted from the inflow of water from Gamak Bay.

      • 磁氣場내 초파리 集團의 發生率 變動과 選擇不利에 관한 遺傳的 硏究

        朴殷圭,朴泰永,崔五木 圓光大學校 1994 論文集 Vol.28 No.2

        本 硏究에서는 韓國 仙遊島 自然集團 野生型 초파리와 可視 突然變異型 黃色體小翅 초파리를 Helmholtz coils를 이용하여 만든 여러 가지 다른 磁氣場內의 集團에서 發生率 變動과 性的 選擇率을 調査하여 選擇不利에 관한 遺傳的 行動을 觀察하고자 實驗을 實施하여 아래와 같은 結果를 얻었다. 1.地球磁氣場內의 초파리 集團과 각각의 Helmholts coils裝置內 초파리 集團의 野生型 + 遺傳子의 頻度가 世代의 進行에 따라 增加하여 평형을 보여 주었다. 2.地球磁氣場內의 초파리集團과 各各의 Helmholts coils裝置內의 초파리 集團의 突然變異型 ym 遺傳子, y 遺傳子, m 遺傳子들의 頻度는 世代의 進行에 따라 減少하여 낮은 頻度의 평형을 보여 주었다. 3.초파리 集團의 發生率 變動은 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 3世代에 4.89%, 地球磁氣場이 消去된 곳에서의 초파리 集團에서 5世代에 12.56%로 큰 變動을 보여주었으며 相異한 磁氣場內 초파리 集團의 全體平均 發生率은 地球磁氣場內의 초파리 集團, Helmholtz coils 裝置를 이용하여 地球磁氣場이 消去된 곳에서의 초파리 集團, 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團, 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 各各 21.59%, 23.48%, 27.79%로 地球磁氣場內의 초파리 集團에서 發生率이 增加함을 보여주었다. 4.+遺傳子를 운반한 染色體의 選擇率은 10世代까지 平均 頻度가 地球磁氣場 內의 초파리 集團, 地球磁氣場이 消去된 곳에서의 초파리 集團, 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團, 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團이 各各 66.11%, 61.05%, 66.12%, 66.18%로 觀察되었다. 이 結果는 地球磁氣場이 消去된 곳에서의 초파리 集團에서 가장 강한 選擇不利를 보여주었다. 5.突然變異型 ym遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리 集團에서 2.81%, 4.99%, 2.12%, 2.82%로 觀察되었다. 이 結果는 地球磁氣場의 3培인 磁氣場內에서의 초파리 集團에서 2.12로 相對的으로 강하게 選擇不利를 보여주었고 地球磁氣場이 消去된 곳에서의 초파리 集團에서 4.99%로 選擇不利가 가장 약하게 작용된 結果를 보여 주었다. 6.突然變異型 y遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리集團에서 3.73%, 3.54%, 2.57%, 2.37%로 觀察되었다. 이 結果는 地球磁氣場의 5培인 磁氣場內에서의 초파리 集團에서 더 높은 選擇不利를 보여 주었다. 7.突然變異型 m遺傳子를 운반한 染色體의 選擇率은 各各의 조절된 磁氣場內의 초파리 集團에서 3.31%, 5.66%, 4.20%, 3.87%로 觀察되었다. 이 結果는 地球磁氣場內의 초파리 集團에서 3.31%로 相對的인 강한 選擇不利를 보여 주었고 地球磁氣場이 消去된 곳에서의 초파리 集團에서 5.66%로 가장 약한 選擇不利를 보여주었다. 8.Duncan's multiple range test의 LSD값으로 有意差異 有無 檢定을 하였던 바 野生型의 A group과 突然變異型의 B group사이에 고도의 有意差異가 있음이 밝혀졌다. 9.本 實驗結果는 地球磁氣場과 여러 가지 다른 磁氣場內의 초파리 集團에서 덜 適應된 초파리로 하여금 실로 짧은 기간에 도태될 수 있게 하는 강력한 性的選擇의 예가 되는 것으로 思料된다. To elucidate the genetic behavior of selective disadventage among visible mutants of Drosophila melanogaster bred and kept by the genetic study laboratory room, Wonkwang University and the wild type collected at Sunyoudo island, and reared under the influence of four different strength of magnetic fields, i.e. the ambient, the without, the treble and the quintuple magnetic field, this study was carried out at the above indicated laboratory room. 1.The shown was that the whole mean emergence rates of the wild type Drosophila melanogaster carrying +gene - bearing chromosome was steadily increased by generation passage finally attained equilibrium, until 10th generation, under the influence of ambient and 3 different magnetic fields generated by Helmholtz coils. 2.Of the Drosophila melanogaster populations either bred in the ambient magnetic field or the magnetic fields of three different strength controlled by Helmholtz coils, the emerhence rates of mutants such as ym gene, y gene and m gene-bearing individuals were decreased with generation passage up to the tenth and also shown the equilibrium of being frequency. 3.The variations of emergence rates of Drosophila melanogaster population altering by generation showed the drastic lowest values at the specified generation, for example, 12.56% under the without magnetic field at the fifth genertion and 4.89% under the quintule magnetic field at the third gereration. The Over-all mean emergence rates of Drosophila melanogaster populations reared in controlled magnetic fields, i.e. the ambient and the without, the treble and the quintuple using Helmholtz coils, showed 21.59%, 23.48%, 27.79% and 27.14% respectively. Referring to these data, the fly population raised in the ambient magnetic field showed a relatively lower emergence rate than any one of the other three populations. 4.The mean selective frequencies of +gene-carrying chromosome up to tenth generation, affected by four different magnetic fields, showed 66.11%, 61.05%, 66.12% and 66.18% with the magnetic field strength as mentioned order before. The data explains that Drosophila melanogaster population reared in the without magnetic field showed the highest selective disadventage. 5.The selective frequencies of the individual of ym gene-bearing chromosomes showed 2.81%, 4.99%, 2.12% and 2.82% by the same order of magnetic field strength indicated above. It was shown that the fly population reared at the treble strength generated by Helmholtz coils cleared the relatively strong selective disadvantage being 2.12%, however the opposite value was 4.99% resulted form the without magnetic field. 6.The selective frequencies of the mutant which carries y gene-bearing chromosome showed 3.73%, 3.54%, 2.57% and 2.37% from the four different magnetic fields in the same magnetic order. The results indicate that the fly population form the quintuple magnetic field showed the higher selective disadvantage frequency, 2.37%. 7.The selective frequencies for the mutants carrying m gene-bearing chromosome were calculated as to be 3.31%, 5.66%, 4.20% and 3.87% for the same order of magnetic field strength. The found from this results is that the selective disadvantage frequency for the mutant rearing ym gene chromosome in the ambient magnetic field was stronger than any one of the other, being 3.31%, however the opposite value was resulted from the without magnetic field 5.66%. 8.Through Duncan's multiple range test and LSD value, the highly significant differences between the wild type and any one of the other three mutants were calculated. 9.As the conclusion obtainable from this experiments, the results indicated that such sexual selection was strong enough to eliminate the less "fit" flies bred under the magnetic field impact in a remarkably short span of time, even for the period of tenth generation is not long enough.

      • 입사파 경계조건을 이용한 핵융합반응 분석

        박규은,이원구,김병택 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.1

        The fusion cross sections induced by heavy-ions are formulated in detail in the basis of the customary barrier penetration model with the incoming wave boundary condition. The theory is applied to the ^12C+^16O system at low energies and explains well the observed fusion data as well as the elastic scattering.

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