http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
The relationship between serum ferritin concentration, smoking and lung function in Korean people
( Eun Kyong Goag ),( Joo Han Song ),( Young Seok Lee ),( Kyung Soo Chung ),( Song Yee Kim ),( Eun Young Kim ),( Ji Ye Jung ),( Young Ae Kang ),( Moo Suk Park ),( Se Kyu Kim ),( Joon Chang ),( Young Sa 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Cigarette smoke induces iron release and may alter iron metabolism and contribute to the increase in the total oxidative burden on the lungs of smokers. In the previous studies, ferritin levels of bronchoalveolar lavage fluid in smoker were elevated. The aim of the present study was to investigate the relationship between serum ferritin concentration, smoking and lung function in Korean people. Methods: This study wasbased on the data acquired in the Forth and Fifth National Health and Nutrition Examination Survey. Among 50,405 subjects, the number of adults who were aged over 40 years old, measured blood levels of ferritin, and performed spirometry properly was 15,239. Results: Of all subjects, 6,613 (43.4%) were male and 8,626 (56.6%) were female. Mean age was 56.5 years for men and 56.9 years for women. The prevalence of airflow obstruction defined by FEV1/FVC. Conclusions: Our data suggest that serum ferritin concentrations increased with smoking and lung function was decreased when serum ferritin levels were low. Further studies are required for investigating the role of ferritin in the development of COPD.
( Eun Kyong Goag ),( Ah Young Leem ),( Song Yee Kim ),( Joo Han Song ),( Kyung Soo Chung ),( Ji Ye Jung ),( Moo Suk Park ),( Young Sam Kim ),( Se Kyu Kim ),( Joon Chang ),( Eun Young Kim ) 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.-
Background: The EGFR mutation T790M is reported in approximately 50% of NSCLC patients with acquired resistance to EGFR-TKI. Recently, its assessment become more important because the 3rd generation EGFR-TKIs targeting T790M mutant NSCLC are developed and become available in the real world. We aim to investigate the feasibility of bronchoscopy as rebiopsy tool and prevalence of T790M mutations after failure of EGFR-TKI. Methods: We investigated 139 patients who had undergone rebiopsy by flexible bronchoscopy (endobronchial biopsy and transbronchial biopsy) and EBUS-TBNA between Sep 2014 and Jul 2016. Results: Of 139 patients, 102(73.4%) were pathologically diagnosed successfully by bronchoscopic rebiopsy. The most common method used for rebiopsy was transbronchial biopsy(41.5%). The EBUS-TBNA and endobronchial biopsy were used in 26.8% and 19.5%. Among them, we selected a total of 41 EGFR-mutant lung adenocarcinoma patients, who had a history of acquired resistance to EGFR-TKI and available tumor tissue for reassessment of EGFR mutations at rebiopsy. Median duration of EGFR-TKI treatment was 10.0 months. Initial EGFR mutation was E19 del(56.1%), L858R or L861Q(34.1%), and others. The T790M mutation was identified in 18(43.9%) patients. The E19 del was most significant factors for T790M development( p=0.002). There was no significant difference in the incidence of T790M according to the type of EGFR-TKI. Conclusion: Bronchoscopic biopsy is feasible for rebiopsy after failure of EGFR-TKI. The T790M mutation is more frequently induced with E19 deletion than L858R and others.
Goag, Eun Kyong,Park, Ji Eun,Lee, Eun Hye,Park, Young Mok,Kim, Chi Young,Lee, Jung Mo,Kim, Young Joo,Kim, Young Sam,Kim, Se Kyu,Chang, Joon,Park, Moo Suk,Chung, Kyung Soo The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
IgG4-related disease is an immune-mediated fibro-inflammatory disease, characterized by lymphoplasmacytic infiltration composed of IgG4-positive plasma cells of various organs with elevated circulating levels of IgG4. This disease is now reported with increasing frequency and usually affects middle-aged men. Massive pleural effusion in children is an uncommon feature in IgG4-related disease. Here, we report a case of a 16-year-old male patient with extensive IgG4-related disease presenting with massive pleural effusion, mediastinal mass, and mesenteric lymphadenopathy.
( Eun Kyong Goag ),( Ji Eun Park ),( Eun Hye Lee ),( Young Mok Park ),( Chi Young Kim ),( Jung Mo Lee ),( Young Joo Kim ),( Young Sam Kim ),( Se Kyu Kim ),( Joon Chang ),( Moo Suk Park ),( Kyung Soo C 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
IgG4-related disease is an immune-mediated fibro-inflammatory disease, characterized by lymphoplasmacytic infiltration composed of IgG4-positive plasma cells of various organs with elevated circulating levels of IgG4. This disease is now reported with increasing frequency and usually affects middle-aged men. Massive pleural effusion in children is an uncommon feature in IgG4-related disease. Here, we report a case of a 16-year-old male patient with extensive IgG4- related disease presenting with massive pleural effusion, mediastinal mass, and mesenteric lymphadenopathy.
Lymphocytic interstitial pneumonia in a patient with Sjögren’s syndrome
Eun-Hye Lee,Ji-eun Park,Eun Kyong Goag,Young Joo Kim,In Young Jung,Chi Young Kim,Youngmok Park,Jung Mo Lee,Moo Suk Park 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder characterized by diffuse infiltration of the pulmonary parenchymal interstitium by polyclonal lymphocytes and plasma cells. LIP has been associated with a variety of clinical conditions; such as connective tissue disorders and other immune system abnormalities. Treatment usually involves administration of corticosteroids and other immunosuppressants. We report on a 38-year-old female patient who complained of shortness of breath, dry mouth, and dry eyes for more than 1 month, and was positive for Raynaud’s phenomenon. Based on surgical biopsy, she was diagnosed as having LIP accompanied by Sjögren’s syndrome. The patient was treated with highdose steroids followed by maintenance therapy for approximately 2 years, and her condition improved.
Lymphocytic interstitial pneumonia in a patient with Sjogren`s syndrome
( Eun Hye Lee ),( Ji Eun Park ),( Eun Kyong Goag ),( Young Joo Kim ),( In Young Jung ),( Chi Young Kim ),( Young Mok Park ),( Jung Mo Lee ),( Moo Suk Park ) 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder characterized by diffuse infiltration of the pulmonary parenchymal interstitium by polyclonal lymphocytes and plasma cells. LIP has been associated with a variety of clinical conditions; such as connective tissue disorders and other immune system abnormalities. Treatment usually involves administration of corticosteroids and other immunosuppressants. We report on a 38-year-old female patient who complained of shortness of breath, dry mouth, and dry eyes for more than 1 month, and was positive for Raynaud`s phenomenon. Based on surgical biopsy, she was diagnosed as having LIP accompanied by Sjogren`s syndrome. The patient was treated with highdose steroids followed by maintenance therapy for approximately 2 years, and her condition improved.
Lymphocytic interstitial pneumonia in a patient with Sjögren's syndrome
Lee, Eun Hye,Park, Ji Eun,Goag, Eun Kyong,Kim, Young Joo,Jung, In Young,Kim, Chi Young,Park, Young Mok,Lee, Jung Mo,Park, Moo Suk Yeungnam University College of Medicine 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder characterized by diffuse infiltration of the pulmonary parenchymal interstitium by polyclonal lymphocytes and plasma cells. LIP has been associated with a variety of clinical conditions; such as connective tissue disorders and other immune system abnormalities. Treatment usually involves administration of corticosteroids and other immunosuppressants. We report on a 38-year-old female patient who complained of shortness of breath, dry mouth, and dry eyes for more than 1 month, and was positive for Raynaud's phenomenon. Based on surgical biopsy, she was diagnosed as having LIP accompanied by $Sj{\ddot{o}}gren^{\prime}s$ syndrome. The patient was treated with high-dose steroids followed by maintenance therapy for approximately 2 years, and her condition improved.
박지은 ( Ji Eun Park ),정수영 ( Su Young Jung ),이지연 ( Ji Yeon Lee ),이은혜 ( Eun Hye Lee ),곽은경 ( Eun Kyong Goag ),이상협 ( Sang Hyub Lee ),차병효 ( Byung Hyo Cha ) 대한췌담도학회 2015 대한췌담도학회지 Vol.20 No.2
75세 남자환자가 3개월 전부터 지속된 복부 불편감과 식욕 저하로 병원을 방문하였고, 복부전산화단층촬영을 시행한 결과 췌장 발육 부전증과 췌장 두부의 종괴, 복막의 비후가 관찰되었다. 자기공명담췌관촬영술과 내시경역행담췌관 조영술에서 주 췌관은 정상이었으나 췌부와 미부의 췌관 및 산토리니관은 관찰되지 않았다. 양전자방출단층촬영에서 복막과 폐의 암전이 소견이 나타났으며, 복수천자에서 얻은 세포검사에서 선암종이 확인되어 타 장기의 전이가 진행된췌장암을 진단하였다. 이에 저자는 췌장암이 동반된 배측 췌장 발육 부전증 1예를 보고하는 바이다. Agenesis of dorsal pancreas (ADP) is an extremely rare congenital anomaly defined as an absence of the dorsal ductal system resulting from failure in the embryologic development of the pancreatic dorsal bud. Most of ADP patients are asymptomatic but some of them suffer recurrent pancreatitis and diabetes. Few number of pancreatic adenocarcinoma in association with ADP has been published previously in other countries. There was no such case reported in Korea. We report a case diagnosed as pancreatic adenocarcinoma with ADP. Korean J Pancreatobiliary 2015;20(2):83-87
Lymphocytic interstitial pneumonia in a patient with Sjögren’s syndrome
이은혜,박지은,Eun Kyong Goag,Young Joo Kim,In Young Jung,Chi Young Kim,박영목,Jung Mo Lee,박무석 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder characterized by diffuse infiltration of the pulmonary parenchymal interstitium by polyclonal lymphocytes and plasma cells. LIP has been associated with a variety of clinical conditions; such as connective tissue disorders and other immune system abnormalities. Treatment usually involves administration of corticosteroids and other immunosuppressants. We report on a 38-year-old female patient who complained of shortness of breath, dry mouth, and dry eyes for more than 1 month, and was positive for Raynaud’s phenomenon. Based on surgical biopsy, she was diagnosed as having LIP accompanied by Sjögren’s syndrome. The patient was treated with highdose steroids followed by maintenance therapy for approximately 2 years, and her condition improved.