자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

신경병증성 통증 모델쥐 뒤뿌리신경절의 Nitric Oxide Synthase 아형 및 NADPH-diaphorase 발현에 관한 연구

정성균,김수일,양은진,류택근,권오유,박경란,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Injury to peripheral nerve somtimes lead to neuropathic pain. Nitric oxide(NO) is increased in the dorsal root ganglia (DRG) of neuropathic pain models, and L-NAME, a nitric oxide synthase (NOS) inhibitor, reduces neuropathic pain. However, it is not known that underlying mechanism of NO involvement in development and maintanence of neuropathic pain. It was found that there were three NOS isoforms-nNOS, eNOS, and iNOS. It is also necessary to investigate NOS isoforms in neuropathic pain. The aim of this study is to investigate NOS isoforms and NADPH-diaphorase expressions and underlying mechanism of NO involvement in neuropathic pain. The 5^th lambar (L5) DRG were obtaind after tight ligation of L5 an L6 spinal nerves for 7 days. Toluidine blue stain, immunohistochemistry for nNOS, eNOS, and iNOS, and NADPH-diaphorase histochemistry were performed. All specimens were observed under light microscope. nNOS expression was increased significantly in the cytoplasm of the DRG of ligated side at 7 day post-ligation (7D PL). eNOS expression was also increased in the blood vessel, a few neurons or satellite cells, and cell membrane of Schwann cells in the DRG of ligated side at 7D PL. iNOS expression was increased in a few blood vessels and cytoplasm of small neurons in the DRG of ligated side at 7D PL. NADPH-diaphorase expression was increased significantly in the neurons of the DRG of ligate side at 7D PL, but NADPH-diaphorase expressions were weak or absent in the blood vessel and Schwann cell in the contralateral DRG and the DRG of ligated side at 7D PL. It is suggested that NOS isoforms may be closely related to development and mantanence of neuropathic pain in order of nNOS>eNOS>iNOS.

고추 탄저병 저항성 중간모본 ‘원예 100005호 ’,‘원예 100006호’ 육성

양은영,김수,채영,채수영,조명철,문지혜,박태성,이우문,곽정호 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

Owing to frequent heavy rain due to abnormal weather, the occurrence of pepper anthracnose has recently increased, which affects the supply and demand of pepper. As a result, the price of red pepper powder in 2011, for example, increased three times compared to the average year. Although anthracnose of pepper plants has been controlled by fungicides until now, it is important to develop new resistant cultivars because of the reduction of the labor force in rural area and occurrence of new anthracnose strains resistant to fungicides. National Institute of Horticultural and Herbal Science developed two pepper lines, ‘Wonye 100005’ and ‘Wonye 100006’ that are resistant to pepper anthracnose. These lines were developed by continuous selection of progenies from a cross between ‘Wonye AR1’, which were developed from interspecific hybridization and ‘TF68’. The anthracnose resistance level of the two lines was higher than that of commercial cultivars and similar to check varieties showing highest level of anthracnose resistance.

폐암으로 오인된 이물질에 의한 기관지 육아종증 1예

정종훈,김소영,김휘정,김학렬,양세훈,정은택 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

간호사의 투약안전 역량 강화를 위한 교육요구 분석

양혜영, 이광희, 홍선영, 이정은 신한대학교 2021 신한대학교 논문집 Vol.44 No.-

The purpose of this study is to present basic data necessary for the development of educational programs to improve nurses' medication safety competency by analyzing educational needs. A survey was conducted on 37 clinical nurses at secondary hospitals or higher in Seoul and Gyeonggi-do. As a result of analyzing the nurse's medication experience, there were no cases of administering expired drugs, but various medication errors occurred. In addition, nurses had many organizational problems in performing oral prescriptions rather than receiving regular instructions for medication. There were six items that showed the largest statistical difference between the group of important and implementation levels of nurse's medication safety competency. In addition, as a result of the Borich’s demand analysis, the highest priority items were "Measures can be established to prevent recurrence in the event of drug side effects" and "Cases can be analyzed to find the root cause of medication errors." Based on the results of this study, follow-up studies on the development of educational programs that can strengthen nurses' medication competency should be conducted.

중안면부 함몰과 하악전돌을 동반한 Ⅲ 급 부정교합자의 교정-악교정수술 복합치료

조은정,김종태,양원식 대한치과교정학회 1996 대한치과교정학회지 Vol.26 No.5

성장이 완료된 골격성 III급 부정교합의 치료는 골격 부조화의 심도, 절치 치축, overbite와 연조직 측모의 심미성 등을 고려하여 필요한 경우 교정치료와 악교정수술을 병행하여 골격과 치아관계 개선에 따른 기능의 증진외에도 안모의 심미성을 증진시킬 수 있다. 특히 전후방적, 수직적, 횡적인 골격 부조화가 크거나 안면비대칭이 있는 경우, 또한 악교정수술후의 안정성이나 보다 이상적인 안모를 위하여 양악수술을 시행한다. 중안면부 함몰환자에서 안와하연과 관골부는 보존하며 비상악체를 전방이동하는 pyramidal Le Fort II osteotomy를 시행할 수 있으며, 안와하연과 관골부의 전방이동을 필요로 할 때는 quadrangular Le Fort II osteotomy를 시행할 수 있다. 이 수술법은 안와하연의 위치를 변화시켜 안와체적에 영향을 미치므로 상악골의 횡적, 수직적 이동량이 5mm 이상일 때는 시행할 수 없다. 서울대학교병원 치과진료부 교정과에 내원하여 중안면부 함몰과 하악전돌을 골격성 III급 부정교합으로 진단되어 교정-악교정수술(Le Fort II osteotomy 와 BSSRO) 복합치료를 받은 2명의 환자에 대해 살펴보고자 한다. In non-growing Class III malocclusion, the critical aspects which determine the need of orthognathic surgery are the severity of skeletal discrepancy, incisor inclination, overbite and soft tissue profile. Two-jaw surgery is more effective in correcting severe sagittal, vertical, transverse skeletal discrepancies and facial asymmetry. And more esthetic and stable profile can be achieved by two-jaw surgery. Some midfacial deficiency patients can be treated by pyramidal Le Fort II osteotomy to maintain infraorbital rim and malar complex and to advance nasomaxillary complex. Others who require advancement of infraorbital rim and malar complex can be treated by quadrangular Le Fort II osteotomy. On the following cases, patients who had represented midfacial deficiency and mandibular prognathism were treated with combined orthodontic-surgical therapy by Le Fort II osteotomy and BSSRO.

네오스트그민 독성에 대한 디펜히드라민 및 프로메사진의 효과

박은희,양근해,전민정 숙명여자대학교 약학연구소 1998 약학논문집-숙명여자대학교 Vol.14 No.-

This study was designed to examine the effects of diphehydramine and promethazine on the toxic manifestation of neostigmine. It was found that diphenhydramine and promethazine increase acetylcholinesterase activity in liver of mice. When diphenhydramine and promethazine was treated before administration of neostigmine, it significantly extend the onset latency in the signs of toxicities which were characteristically produced by neostigmine and it also prevented lethality in all of the animals.

남성·여성의 혼합DNA에서 Y-STR의 유효성 검토

이양한,신상철,이은정,박정우,구형남,김대열,김윤신 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

악교정 수술중 수액요법과 술후 합병증의 연관성

류정호,김대윤,배준수,양병은,유준영,김용관 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.5

Few topics in operative and perioperative patient management generate more controversy than that of appropriate fluid and electrolyte therapy. especially, controversy has swirled around colloid vs crystalloid therapy and the composition of administered fluids, agreement among clinicians as to what fluid therapy is appropriate, and in what amount, is rare. This controversy likely will be enhanced by Arieff' s provocative article. He described 11 adults and 2 pediatric patients. All developed fatal postoperative pulmonary edema, seemingly caused solely by excessive postoperative fluid administration. From January 1999 to December 1999, we investigated 24 patients, which were operated by orthognathic surgery, about the intraoperative fluid therapy and the associated effect in orthognathic surgery, which is regarded as one of the major surgery of oral and maxillofacial surgery. First, They were devided into two groups, that is one-jaw surgery and two-jaw surgery, and each groups were devided by intraoperative fluid volume of 8ml/kg/hr. Subjective assesment was collected through use of a series of 3 questionnaries. In each questionnaire, a 5-point Liekert scale was used far assessment of following parameters of recovery from anesthesia: headache, dizziness, drowsiness, nausea/vomiting, thirst. The patient completed questionnaire 1 at 4 hour after surgery, questionnaire 2 was completed at 24 hours after surgery, and questionnaire 3 was completed at 48 hours after surgery. This study demonstrated that appropriated perioperative rehydration decreases postoperative adverse outcomes and improved the patient's perception of the postoperative period.

하이퍼텍스트 유형과 자기주도성이 학업성취에 미치는 효과

박정환,양은영 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.4

본 연구의 목적은 하이퍼텍스트 유형과 자기주도성이 학업성취에 미치는 효과를 규명하려는 것이다. 이를 위해 경기 H시 소재 H고등학교 1학년 2학급 69명을 대상으로 자기주도성 검사를 실시하여 평균점수 이상을 얻은 학생을 자기주도성이 높은 집단으로, 그 미만을 얻은 학생을 자지주도성이 낮은 집단으로 분류하여 실험처치를 하였다. 연구 결과, 하이퍼텍스트 유형은 학업성취에 영향을 미치지 않았으나 학습자의 자기주도성은 학업성취도에 영향을 미치는 것으로 나타났다. 또한 하이퍼텍스트 유형과 학습자의 자기주도성이 학업성취도에 미치는 상호작용 효과가 있는 것으로 밝혀졌다. 본 연구는 비교적 짧은 기간에 이루어져 지속적인 학습효과를 검증하는데 한계가 있기 때문에 장기간에 걸친 연구가 필요하다. 또한 자기주도성 이외의 학습자 특성을 고려한 연구와 컴퓨터일반 교과 외 다양한 학습내용으로 하는 후속 연구가 필요하다. The purpose of this study was to find effects of hypertext structure and self-direction on learning performance. To reach the goal, we got 69 H highschool students and tested self-direction we treat hypertext program to them. The results found were that hypertext style(non-structure, structure) didn’t effect on academic achievement but did effect learner’s self direction. Also, we found interactive effect of hypertext structure and self-direction on academic achievement. Following studies have limits verified learning effect, because this studies are carried out in short-term research. Further studies need the study of effect of hypertext structure and self-direction on academic achievement for a long-term research. Also, further studies should accomplish the study considering learner characteristics besides self-direction and will need succeeding studies including various learning contents besides computer general curriculum.