열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

소비자의 라이프스타일과 케이블TV 홈쇼핑 의류제품에 관한 연구

강영의,이옥희,최경은 복식문화학회 2001 服飾文化硏究 Vol.9 No.3

The purpose of this study was to classify consumer groups according to the life styles and analyze buying intention and evaluation criteria of apparel product, opinion to 4p's aspect among consumer groups. And it was to clarify relationships between the experience of CATV home shopping and buying intention and evaluation criteria of apparel products opinion to 4p's aspect. The subjects of this study were 270 women living in Chonbuk and Chonnam regardless their experience in CATV home shopping. For data analysis, frequency, percentage, mean, t-test, factor analysis were conducted. The results were as follows; First, the type of life style were classified into the following subdivisions: products confirmed type, price-quality regarded type, time regarded type, new product regarded type. Second, the significant differences among the classified life style groups were found in buying intention, evaluation criteria of apparel product, and opinion to 4p's aspect. Third, there were significant differences in buying intention, evaluation criteria of apparel product, and opinion to 4p's aspect according to TV home shopping experience.

액체소듐속에서 소듐-물반응에 의한 재질의 Wastage현상

정경채,정지영,김병호,김태준,최병해,최종현,김의식 한국공업화학회 2003 응용화학 Vol.7 No.1

In this study we observed and analyzed the corrosion phenomena in leak site and the effect on temperature at the target surface of heat transfer tube material by sodium-water reaction through water leakage in liquid sodium atmosphere. Surrounding of leak hole of the specimen was damaged by the wastage phenomena due to corrosion and erosion of material, and hole size by damage of leak site was extended from 150㎛ to about 200㎛. Also, the damaged size appeared in the target surface was observed to about 1000㎛ diameter. The temperature of target surface increased about 70~80℃ by the heat of sodium-water reaction even with the small leakage of 15㎖ water. From the results of EPMA and EDX analysis, damaged area are found to covered with complex compounds such as (NaOH+Na_2O) FexOy or (NaCrO_2+nA_2CrO4) mixed up with the sodium oxides by sodium-water reaction and the Fe or Cr element by matrix of tube sodium oxides by matrix of tube material.

인공 치아우식 발생 모델에서 디지털 방사선 공제술을 이용한 인접면 치아우식증의 진단

박정훈,최용석,황의환,이기자,최삼진,박영호,김경숙,진현석,홍경원,오범석,박헌국 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.1

Purpose : The purpose of the experiment was to evaluating the diagnostic ability of dental caries detection using digital subtraction in the artificial caries activity model. Materials and Methods : Digital radiographies of five teeth with 8 proximal surfaces were obtained by CCD sensor (Kodak RVG 6100 using a size #2). The digital radiographic images and subtraction images from artificial proximal caries were examined and interpreted. In this study, we proposed novel caries detection method which could diagnose the dental proximal caries from single digital radiographic image. Results : In artificial caries activity model, the range of lesional depth was 572-1,374 μm and the range of lesional area was 36.95-138.52mm². The lesional depth and the area were significantly increased with demineralization time (p<0.001). Furthermore, the proximal caries detection using digital subtraction radiography showed high detection rate compared to the proximal caries examination using simple digital radiograph. Conclusion : The results demonstrated that the digital subtraction radiography from single radiographic image of artificial caries was highly efficient in the detection of dental caries compared to the data from simple digital radiograph.

영양소제거 공정의 기질 정량관계에 대한 온도와 기질부하의 영향

하준수,최의소,박재홍,길경익,김성원 대한상하수도학회 2003 상하수도학회지 Vol.17 No.6

This research has been performed to evaluate the stoichiometric relationship between removed COD and nitrogen or phosphorus. A modified A²/O process, which was equipped with an external nitrification tank and a switching reactor, was operated with a capacity of 50㎥/d. From the results, it has been concluded that the stoichiometric values were varied by temperature condition or input COD loads. In case of denitirfication, the requirement g COD for removed nitrate nitrogen ranged 0.13 to 10.5g, and the compensation coefficient of temperature was evaluated as 1.028. For phosphorus removal, the required COD was about 7.5gCOD_(consumed)/gP_(released) and 0.54gPHACOD_(storage)/gP_(uptake). During rainy season, as it appeared a lower organic substrate loads, the PHA(Poly Hydroxy Alkanoate) contents of biomass was reduced. From the relationship between influent BOD, and the sum of removed TN and TP, the ratio for rainy and winter season was about 4.8 and 5.8g BOD/g (TN+TP) each others. Therefor, the substrat ratios for nitrogen and phosphorus removal appeared to be affected by temperature and influent organic substrate loads.

골격계의 원발성, 전이성 혈관외피세포종 : 증례 보고

김동수,김용민,최의성,손현철,박경진,조병기,이형준 충북대학교 의과대학 충북대학교 의학연구소 2009 忠北醫大學術誌 Vol.19 No.2

혈관악성종양은 혈관내피종(hemangioendothelioma), 혈관육종(angiosarcoma), 혈관외피세포종(hemangio pericytoma) 및 카포지 육종(Kposi's sarcoma) 등이 있으며, 이 중 혈관외피세포종은 비전형적인 외피 세포가 증식된 경우를 말한다. 골의 혈관외피세포종은 드문 악성종양으로 문헌상 보고되어 있는 예들은 주로 성인의 대퇴골, 골반골에 발생된 경우이다. 이 경우 원발성은 드물며 주로 비골격계에서 기원하여 골로 전이되어 발생하는 것으로 알려져 있다. 남녀 발생 빈도는 거의 동일하며, 12세부터 90세까지 어느 연령층에서도 발생할 수 있으나, 호발 연령은 40대에서 50대 사이 이다. 대개 연부조직 종양으로 신체 어디에서도 일어날 수 있고, 하지 특히 서혜부 및 대퇴부에서 가장 많이 발생하며, 후복막, 두경부 및 흉복부의 순으로 나타난다. 전이도 빈번하게 발생하는데, 그 경로는 주로 혈행성으로, 발생부위는 폐와 골이 제일 많다. 저자들은 8년 전, 우측 아래턱의 원발성 혈관외피세포종으로 절제술을 시행한 환자에서 술후 3년 뒤, 우 경골 근위부에 원격 전이가 발생하여 절제술, 예방적 골수강내 금속정 삽입술 및 골시멘트 충전술을 시행하였다. 현재 2차 수술 후 5년여가 경과한 상태로 경골에 재발의 증거가 없어 만족할 결과를 가져다주었다고 판단하여 문헌 고찰과 함께 보고하는 바이다. Hemangiopericytoma is a rare tumor of blood vessels, first described and named by Stout and Murray in 1942, arising from the contractile, elongated cells the pericytes of Zimmermann which surround capillaries. It can develop whereever there are capillaries and mostly in the connective tissue of the human body. It can also develop in any age from 12 to 90 years, and the rate of metastasis and prognosis depend on its histologic grade. We report a case of hemangiopericytoma metastasized to the right proximal tibia from the right mandible, resected three years ago. The hemangiopericytoma is a extremely rare primary malignant tumor in the bone and bone to bone metastasis is never been found in the literature before. So, we report this case and also report the good result.

14세 여환에서 쇄골에 발생한 동맥류성 골 낭종 : 증례보고

김동수,김용민,최의성,손현철,박경진,조병기,홍경호 충북대학교 의과대학 충북대학교 의학연구소 2010 忠北醫大學術誌 Vol.20 No.1

동맥류성 골낭종(aneurysmal bone cyst)은 Jaffe와 Lichtenstein(1942)에 의해 처음 기술된 이래 많은 증례가 보고되었다. 동맥류성 골낭종은 주로 장관 골의 골간단과 척추에서 발생한다. 병인은 정확히 밝혀지지 않았으나, 반응성 현상으로 생각되며, 원발성 또는 다른 병변과 동반될 수 있다. 쇄골 등 기타 골에서 발생하는 경우는 매우 드물다. 저자들은 우측 쇄골에서 동맥류성 골낭종 1예를 경험하여 보고하는 바이다. 14세 여자환자가 우측 견갑부의 우연히 발견된 종괴를 주소로 내원하였다. 환자는 종괴에 대해 이학적 검사 및 혈액 검사상 측이한 소견을 보이지 않았다. 방사선 검사상, 쇄골 내측부에 골 용해성으로 팽윤된 병변이 관찰되었고, 동맥류성 골낭종, 단순 골낭종, 전이성 골종양 등의 의증 하에 절제술을 시행하였다. 절제된 종괴의 육안 소견상, 얇은피질 골로 쌓여 있으며, 노란색 액체로 차있는 4x5cm 종괴가 관찰되었고, 완전 절제술을 시행하였다. 광학현미경상, 혈액으로 차있는 다양한 크기의 낭성 구조가 보였고, 여러 개의 거대세포가 격막을 이루고 있었다. 조직학적 소견과 MRI소견, 임상 소견을 종합하였을 때, 쇄골에서 원발성으로 발생한 동맥류성 골낭종을 진단할 수 있었다. Many cases of aneurysmal bone cyst(ABC) have been reported since Jaffe and Lichtenstein(1942) first reported. Aneurysmal bone cyst mostly occurs in metaphysis of the long bones and vertebral column. The reason for this disease has not be clearly explained yet, but it is estimated as reactive change and can be accompanied with primary lesion or another lesion. It rarely occurs in clavicle or other bones. We report one case of ABC in right clavicle. 14-year-old female patient who accidentally found palpable mass on right shoulder visited hospital. We did not find any specifics regarding this patient's mass after physical exam and blood test. Radiologic exam showed a large expansile mass with osteolytic lesion, The differential diagnosis includes ABC, simple bone cyst, metastatic bone tumor, etc. Based on visual observation on excised 4×5 cm mass, it was covered by thin cortical bone and filled with yellow fluid, and complete excision was done. On histological examination, the mass consist of various size of cystic structures. and several giant cells comprised septae. Based on histological examination, MRI, clinical examination, we made a diagnosis that it was primary anuerysmal bone cyst in clavicle

Digora 영상시스템을 이용한 인접면 인공 치아우식병소의 진단능에 관한 연구

김재덕,오경란,최의환 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.2

Digora system is an intraoral indirect digital radiography system utilizing storage phosphor image plate. It has wide dynamic range which allows it to decrease the patient's exposure time and may increase diagnostic ability through image processing (such as edge enhancement, grey scale conversion, brightness change, and contrast enhancement). And also, ti can transmit and storage image information. The purpose of this study was to evaluate the diagnostic ability of artificial proximal caries between Conventional radiograph and Digora images(unenhanced image, brightness & contrast controlled image, and edge enhanced image). ROC(Receiver Operating Characteristic) analysis, paired t-test, and F-tests were done for the statistical evaluation of detectability. The following results were acquired: 1. In Grade I lesions, the mean ROC areas of Conventional radiograph, Digora unenhanced image, Digora controlled image, and Digora edge enhanced image were 0.953, 0.933, 0.965, 0.978 (p>0.05). 2. In Grade II lesions, the mean ROC areas of Conventional radiograph, Digora unenhanced image, Digora controlled image, and Digora edge enhanced image were 0.969, 0.964, 0.988, 0.994. Among theses areas, there was just statistical significance between Diagnostic abilities of Digora edge enhanced image and Conventional rediograph(p<0.05). 3. In the Interobserver variability, the ROC curve areas of Digora edge enhanced image was lowermost in these areas, regardless of the Carious lesion depths. In conclusion, intraoral indirect digital system, Digora system has the potential possibility as an alternative of Conventional radiograph in the diagnosis of proximal caries.

장기적 흡인 배액법을 이용한 척추 후방 기기 고정술 후 감염의 치료

김용민,김동수,최의성,손현철,박경진,김융성 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구 목적 : 척추경 나사못을 이용한 척추 후방 기기 고정술 후 심부 감염이 발생한 증례 들을 대상으로 관련 인자를 분석하고 Hemo-vac을 이용한 장기간의 폐쇄성 흡인 배액법을 통한 치료와 그 결과에 대해 알아보고자 하였다. 대상 및 방법 : 1996년 5월부터 2001년 8월까지 척추후방기기고정술 후 심부 감염이 발생 한 5례를 연구 대상으로 하여 전신 질환 동반, 감염의 발현 양상을 조사하였고, 창상 세척 등 감염 수술 후 장기적 배액법을 이용한 치료 과정 및 최종 결과를 후향적으로 분석하였다. 결 과 : 당뇨와 비만이 술후 심부 감염의 위험요인으로 분석되었다. 수술 환부로부터의 배농, 발열 등 감염 증상은 술후 평균 18.8(8-36)일에 발현되기 시작하였다. 일인당 단 1회의 세척술이 실시되었고 고정기기는 제거하지 않았다. 이후 평균 19.2일간의 지속적 흡인 배농 및 평균 43.6일간의 항생제 정맥투여에 이은 평균 33.8일간의 경구투여로 심부감염은 특별한 합병증 없이 모두 치료되었으며 양호한 임상적 결과와 후외방 골융합을 얻을 수 있었다. 결 론: 척추 후방 기기 고정술 후 발생한 심부 감염에 대해 창상의 세척 및 육아조직 제 거 후 항생제 투여와 Hemo-vac을 이용한 장기간의 장기적 흡인 배액법은 감염의 조절과 척추의 안정성을 동시에 얻을 수 있는 유용한 방법중 하나인 것으로 생각되었다 Purpose: Various treatment modalities have been applied to control deep infection after spinal instrumentation. Validity of removing implants to control the infection is still contro- versial because it may cause loss of spinal stability. Analysis of the inherent risk factors associated with deep infection and the efficacy of management with long-term suction drainage without removal of implants. Materials and Methods : Fiye cases of postoperative deep infection after posterior spinal fixation from May 1996 to August 2001 were investigated on combined general ill- ness, features of infection, various profiles on the management of infection with surgical irrigation and debridement followed by long-term suction drainage, and final outcomes. Results :Remarkable risk factors were diabetes and obesity. Evidences of infection such as discharge from the wound, dehiscence, or fever were observed on the average of 18.8th day postoperatively By only one additional surgical procedure for each patient followed by long-term suction drainage for mean 19.2 days and administration of intravenous antibiotics for average of 43.6 days, deep infections were controlled successfully without removal of implants and without any grave complications. All achieved favorable clinical results and posterolateral fusion. Conclusion : Irrigation and debridement accompanied by long-term suction drainage using Hemo-vac and administration of susceptible antibiotics seemed to be one of the effective methods to control deep infection after posterior spinal instrumentation and main than the postoperative stability of spine.

골반 경사로 인한 요추부 측만증에서 신발 높이기의 효과

김용민,김동수,최의성,손현철,박경진,김융성 대한척추외과학회 2004 대한척추외과학회지 Vol.11 No.2