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Emily J. Watts,Yu Shen,Ephraim P. Lansky,Eviatar Nevo,Gerd Bobe,Maret G Traber 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.2
Vitamin E is an essential human nutrient that was first isolated from wheat. Emmer wheat, the cereal of Old World agriculture and a precursor to durum wheat, grows wild in the Fertile Crescent. Evolution Canyon, Israel, provides a microsite that models effects of contrasting environments. The north-facing and south-facing slopes exhibit low and high stress environments, respectively. Wild emmer wheat seeds were collected from both slopes and seed tocochromanol contents measured to test the hypothesis that high stress alters emmer wheat seed tocol-omics. Seeds from high stress areas contained more total vitamin E (108 ± 15 nmol/g) than seeds from low stress environments (80 ± 17 nmol/g, P = .0004). Vitamin E profiles within samples from these different environments revealed significant differences in isoform concentrations. Within each region, β- plus γ-tocotrienols represented the highest concentration of wheat tocotrienols (high stress, P < .0001; low stress, P < .0001), while α-tocopherol represented the highest concentration of the tocopherols (high stress, P = .0002; low stress, P < .0001). Percentages of both δ-tocotrienol and δ-tocopherol increased in high stress conditions. Changes under higher stress apparently are due to increased pathway flux toward more tocotrienol production. The production of more δ-isoforms suggests increased flow through a divergent path controlled by the VTE1 gene. Hence, stress conditions alter plant responses such that vitamin E profiles are changed, likely an attempt to provide additional antioxidant activity to promote seed viability and longevity.
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( Anuk Kruavit ),( Eugene Teh ),( Imogen Clark ),( Emily Shen ),( Vikas Wadhwa Eastern Health ),( Australia ),( University Of Melbourne ),( Australia ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Acute exacerbations of chronic obstructive pulmonary disease(COPD) places signifi cant pressure on the health care system. Studies have shown that music therapy has positive effects on quality of life and increases exercise capacity of patients. Our aim is to evaluate the effects of music on exercise capacity in COPD inpatients. Method: This was a prospective, interventional study invoving patients admitted with an acute exacerbation of COPD. Patients were given a list of song options to select from. Patients will select a preferred song rated as the best motivational score, as per the Brunel Music Rating Inventory. Patients then undertook a 2-minute walking test to assess the distance walked with and without music. A dyspnoea visual analogue scale was used to record the degree of dyspnoea after each walking test. Secondary outcomes included walking time, blood pressure, heart rate, respiratory rate and oxygen saturation with and without music. Results: Seventeen patients were recruited, with a mean age of 73.9 ± 8.6 years. Nine were males and 8 were females. There was a signifi cant increase in the walking distance with music therapy, with a mean increase in distance of 7.94 metres (95% CI, 3.58 - 12.31). There was a non-signifi cant trend that patients could walk for longer with music therapy. Diastolic blood pressure were noted to increase signifi cantly with music therapy, but other physiological parameters did not show any signifi cant changes. The motivational score of the preferred song used did not lead to any signifi cant correlation with the outcome variables. Conclusion: Music therapy with a patient-preferred song may lead to signifi cant clinical benefi ts in hospital inpatients with acute exacerbation of COPD. Larger studies are warranted to provide further evidence for its potential use in routine clinical practice.
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