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      • 항공기 착륙장치의 충격흡수특성해석

        김두만,임경호,황재혁,이환규 한국항공대학교 1992 論文集 Vol.30 No.-

        본 연구를 통하여 항공기 착륙장치의 거동(동특성 및 완충기 효율)을 해석하고 평가하는 Software를 개발하엿다. 이 프로그램을 개발하기 위해 착륙장치를 2개의 자유도를 가지는 동역학시스템으로 모델링하고 운동방정식을 유도하였다. 또한 완충기에 작용하는 내력(즉 공기력, orifice force, friction force)을 표현하는 관계식을 정립하였으며, 타이어의 힘을 표현하는 관계식을 유도하였다. 그리고 운동방정식에는 타이어의 Spin Up운동도 고려되었다. 선정된 항공기의 착륙장치의 Parameter의 값을 프로그램의 입력 Data로 사용했을 때 매우 신뢰할 만한 동특성의 결과를 얻었으며, 특히 Drop Test 결과와 본 연구에서 개발된 Software에서 얻어진 결과를 비교했을 때 매우 흡사한 결과를 얻었다. 따라서 본 연구에서 개발된 Software는 앞으로 국산화되는 착륙장치의 개발 및 설계에 매우 유용하게 사용될 것으로 판단된다. 또한 본 연구에서 사용된 입력 Data중 중요한 10개의 Parameter를 선정하여, 각 Parsmeter를 변화시키면서 착륙장치의 동특성 및 효율의 변화를 고찰해 보았다. 완충기 설계시 가장 중요한 Parameter들은 K-factor, Orifice 단면적 등과 같은 완충기의 변수로 사료되며, 타이어의 변수 T??이나 b는 중요한 변수가 아님을 확인하였다. 또한 항공기의 무게 W, Wheel/Tire의 무게, 완충기의 초기 공기압 P??, 항공역학계수 A도 착륙장치의 효율에는 크게 영향을 미치지 않고 있음을 고찰하였다. 그러나 공기실의 Politropic 지수 n, 항공기의 수직착륙속도 V는 착륙장치의 효융에 Non-Monotonic하게 영향을 미치는 것을 고찰하였다. The software which analysis and evaluate the dynamic characteristics of an landing gear has been developed in this study. The landing gear system has been modelled to be 2 DOF dynamic system to drive the equation of motion. The three internal forces, which are air pressure force, orifice force, and friction force, has been formulated and also the tire force has been formulated and also the tire force has been derived. When the typical values of the design parameters is applied to the developed software, the reliable results of the dynamic characteristics are obtained. Furthermore there is a good agreement between the simulation results and experimental drop test extracted from relevant literatures. It can be concluded that the developed software will be useful for the design and development of a landing gear system inside Korea.

      • 젊은 여성 유방암 환자에서 스테로이드 호르몬 수용체 상태와 싸이클린 D1 과발현의 예후 분석

        최두호,이민혁 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

        Background and Objects : The purpose of this study was to determine the prognostic significance of estrogen receptor (ER) and progesterone receptor (PR) status and cyclin D1 overexpression in Korean women with early-onset breast cancer. Materials and Methods : Sixty women diagnosed and treated with breast cancer at the age of 45 or younger at Soonchunhyang University Hospital were entered for this study. The median age was 37years and follow-up periods were between 80 and 30 months. Paraffin embedded blocks of the primary tumor were processed for immunohistochemical staining of ER, PR and cyclin D1. Close follow-up data were entered in the database for analysis of the prognostic signifinance. Results : The proportion of the tumors staining positive for ER, PR and cyclin D1 were 45.7%, 44.1% 40.7%, respectively. No association was found between immunoreactivity of these markes and axiliary lymph node metastais. The expression of ER correlated with expression of PR and cyclin D1(p<0.001). Lymph node metastasis revealed a poor prognostic factor, but these 3 markers were not prognostic factors in these cohorts of patients, although trends toward poor outcome were observed among patients with negative staining. Conclusions : Cyclin D1 and steroid hormone receptor status were not significant prognostic factors in young women with breast cancer. Large-scaled studies are needed for evaluation of prognostic significance of these immunohistochemical markers in Korean women with early-onset breast cancer.

      • 유카 Ag-aide가 페어리링 병이 발생한 잔디토양의 투수계수 및 한지형 잔디 생육에 미치는 영향

        김두환,이재필,함선규,장진혁,김성태 건국대학교 농업자원개발연구소 2000 農資源開發論集 Vol.22 No.-

        Yucca Ag-aide extracted from Yucca, Agavaceae, is one of the several surface active agents being marked as a soil conditioner for turfgrass. According to the previous research, Yucca can provide an energy source for soil microbes, improve physical properties, and nutrient efficiency in soil, and enhance water infiltration capacity of soil. Yucca was applied to the tee area with cool-season grass showing fairy ring symptom at the Asiana Country Club from June to July, 1999. Yucca was also applied to "Pencross" creeping bentgrass that was stressed by 15 and 30 times of glass stick once every two months(three time total) in 5cm diameter of PVC pipe in greenhouse and to experiment field, established with 35% Tall fescue+50% Kentucky bluegrass+15%Perennial ryegrass at the Kon-kuk University on June 8, 1999. Infiltration at the tee area showing fairy ring symptom was improved by treatment of 250 and 500 fold of Yucca Ag-aide. Yucca Ag-aide treatment also improved root length and dry weight of creeping bentgrass with the stress by glass stick. Coverage and turf quality of cool-season turfgrass in field trial were increased by Yucca Ag-aide. Clipping dry weight was also increased by the treatment.

      • OpenCV와 Tesseract를 이용한 번역기

        이지은,이종길,최성혁,최혁두 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

        In this paper, when receiving image input from various angles from an electronic medium such as a smartphone, a system for recognizing and translating characters by processing images in the image is presented. The translator designed in this paper processed images using a library called OpenCV. Through OpenCV, the boundary of the image can be found, and the distorted image is corrected. After that, Tesseract-OCR was used to enable the computer to convert the characters displayed in the image into strings. After transforming the image that was not placed forward as a function of OpneCV in the forward direction, Tesseract was applied to the deformed image. Characters in images from various angles were recognized, translated using Google Translation API, and the results were displayed on the image and presented.

      • 수입각증후군에 의한 급성 복증 1례

        정은욱,지삼룡,이영태,박지훈,김동기,제인수,채두근,박성재,박은택,이연재,이상혁,설상영,정정명 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

        Afferent loop syndrome is an uncommon complication of a gastrectomy and Billroth Ⅱ reconstruction. It may cause symtoms at any time from the first postoperative day to many years after the gastrectomy. Afferent loop syndrome is characterized by abdominal pain, vomiting and elevation of serum amylase. Thus, it is difficult to differentiate afferent loop syndrome from other cause of acute pancreatitis. However, the history of gastrectomy can be an important clue for diagnosing afferent loop syndrome. We experienced one case of chronic afferent loop syndrome with acute pancreatitis. After appropriate management, the abdominal pain disappeared and serum amylase level decreased. We report this case with a review of relevant literatures.

      • 울진원자력발전소 주변 소나무림의 종조성과 군락 특성

        방제용,전영문,변두원,류병혁,이호준 建國大學校基礎科學硏究所 1995 理學論集 Vol.20 No.-

        울진원자력발전소 주변 소나무림의 종조성과 군락특성을 1994년 3월부터 95년 2월까지 조사한 결과는 다음과 같다. 소나무군락은 상수리나무하위군락과 산철쭉하위군락으로 분류되었으며, 전조사방형구 내에서 출현한 종수는 총 116종으로 상수리나무하위군락과 산철쭉하위군락에서 방형구당 출현종수는 각각 28종, 23종으로 나타났다. 소나무군락의 계층별 평균 수고와 식피율은 상수리나무하위군락에서 교목층이 각각 13.5m와 78.8%, 아교목층이 6m와 37.5%, 관목층이 1.9m와 53.6%, 초본층이 0.4m와 64.4%, 산철쭉하위군락에서는 교목층이 13m와 83.8%, 아교목층이 5.5m와 52.5%, 관목층이 1.9m와 57.5%, 초본층이 0.6m와 69.4%로 나타났다. 피복지수에 의한 계층별 우점순위는 교목층과 아교목층에서 각각 소나무가 8437.5, 1111.3으로 나타났고 관목층에서 진달래(2638.5), 초본층에서 큰기름새(1048.2)가 가장 높게 나타났다. 소나무의 DBH별 분포를 보면 11-15cm급이 상수리나무하위군락과 산철쭉하위군락에서 각각 29.1%(4.2 individuals/a), 26.7%(4.5 individual/a)로 가장 높게 나타났다. 현존식생도에 따른 각 식생형의 분포면적은 소나무림이 133.1k㎡(80.5%), 경작지와 주거지 28.7k㎡(16.2%), 곰솔림 1.8k㎡(1.1%) 순으로 나타났다. 녹지자연도의 등급별 분포는 7등급(이차림)이 70.4%, 2등급(경작지와 주거지) 17.4%, 8등급(이차림) 11.6%, 4등급(벌목지) 0.2%, 6등급(인공조림지) 0.1% 순으로 나타났다. Montreal model에 의한 소나무림의 식물현존량은 3,077,327.8ton으로 산정되었다. The floristic composition and community characteristics of Pinus densiflora forest in vicinity of Ulchin Atomic Power Plant were surveyed from March, 1994 through February, 1995. The results obtained are summarized as follows: The Pinus densiflora community was classified into the subcommunity of Quercus acutissima and Rhododendron yedoence var. poukhanense. The total number of species appearing in the entire surveyed quadrats was 116 sepcies, then 28 and 23 species per quadrat in Quercus acutissima subcommunity and Rhododendron yedoence var. poukhanense subcommunity, respectively. Tree height and vegetation cover by the layer of the Pinus densiflora community were 5m and 78.8% in tree layer, in subtree layer(6m, 37.5%), in shrub layer(1.9m, 53.8%) and in herb layer(0.4m, 64.4%) in Quercus acutissima subcommunity, and in tree layer(13m, 83.8%), in subtree layer(5.5m, 52.5%), in shrub layer(1.9m, 57.5%) and in herb layer(0.6m, 69.4%) in Rhododendron yedoence var. poukhanense subcommunity. The dominance sequences on each stratum determined by the coverage index showed that Pinus densiflora was most dominant in tree layer with 8437.5 and in subtree layer with 1111.3, Rhododendron yedoence var. poukhanense in shrub layer with 2638.5, and Spodiopogon sibiricus in herb layer with 1048.2 value. The highest value of diameter breast height(DBH) distritued in the range of 11~15cm in Quercus acutissima subcommunity(29.1%, 4.2 individuals/a) and Rhododendron yedoence var. poukhanense subcommunity(26.7%, 4.5 individuals/a), respectively. The distribution area of each vegetation type in the actual vegetation map was 80.5% in Pinus densiflora forest, 16.2% in cultivated land and residential section, and 1.1% in Pinus thunbergii forest. The distribution of the degree of green naturality(DGN) was 70.4% in the 7th grade(second forest), 17.4% in the 2nd grade(cultivated land and residential section), 11.6% in the 7th grade(second forest), 0.2% in the 4th grade(cutted area), and 0.1% in the 6th grade(afforestation). It was estimated that phytomass of Pinus densiflora in the study sites, which was calculated by Montreal model, was 3,077,327.8ton.

      • KCI등재

        Comparison of Acarbose and Voglibose in Diabetes Patients Who Are Inadequately Controlled with Basal Insulin Treatment: Randomized, Parallel, Open-Label, Active-Controlled Study

        Lee, Mi Young,Choi, Dong Seop,Lee, Moon Kyu,Lee, Hyoung Woo,Park, Tae Sun,Kim, Doo Man,Chung, Choon Hee,Kim, Duk Kyu,Kim, In Joo,Jang, Hak Chul,Park, Yong Soo,Kwon, Hyuk Sang,Lee, Seung Hun,Shin, Hee The Korean Academy of Medical Sciences 2014 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.29 No.1

        <P>We studied the efficacy and safety of acarbose in comparison with voglibose in type 2 diabetes patients whose blood glucose levels were inadequately controlled with basal insulin alone or in combination with metformin (or a sulfonylurea). This study was a 24-week prospective, open-label, randomized, active-controlled multi-center study. Participants were randomized to receive either acarbose (n=59, 300 mg/day) or voglibose (n=62, 0.9 mg/day). The mean HbA<SUB>1c</SUB> at week 24 was significantly decreased approximately 0.7% from baseline in both acarbose (from 8.43% ± 0.71% to 7.71% ± 0.93%) and voglibose groups (from 8.38% ± 0.73% to 7.68% ± 0.94%). The mean fasting plasma glucose level and self-monitoring of blood glucose data from 1 hr before and after each meal were significantly decreased at week 24 in comparison to baseline in both groups. The levels 1 hr after dinner at week 24 were significantly decreased in the acarbose group (from 233.54 ± 69.38 to 176.80 ± 46.63 mg/dL) compared with the voglibose group (from 224.18 ± 70.07 to 193.01 ± 55.39 mg/dL). In conclusion, both acarbose and voglibose are efficacious and safe in patients with type 2 diabetes who are inadequately controlled with basal insulin. (ClinicalTrials.gov number, NCT00970528)</P>

      • Blood pressure–targeted stepwise resuscitation for hemorrhagic shock in rats

        Lee, Jae Hyuk,Kim, Kyuseok,Jo, You Hwan,Kim, Min A,Lee, Kyoung-Bun,Rhee, Joong Eui,Doo, Ah-Reum,Lee, Min Ji,Park, Chan Jong,Kim, Joonghee,Chung, Heajin Lippincott Williams Wilkins, Inc. 2014 The journal of trauma and acute care surgery Vol.76 No.3

        BACKGROUND: Generation of reactive oxygen species (ROS) is an important mechanism of ischemia-reperfusion injury. Abrupt reoxygenation compared with slow reoxygenation has been known to increase ROS generation. Thus, slow and stepwise reperfusion can reduce ROS generation and subsequent ischemia-reperfusion injury. This study investigated the effect of slow reperfusion by blood pressure–targeted stepwise resuscitation (PSR) in hemorrhagic shock. METHODS: Pressure-controlled hemorrhagic shock was induced in male Sprague-Dawley rats for 1 hour. Rats were then allocated to one of three groups (no-resuscitation group, n = 14; PSR group, n = 15; rapid normalization of blood pressure (RR) group, n = 15). Survival time and hemodynamic changes were recorded and compared. Blood samples and liver tissue were harvested after 6 hours of resuscitation in surviving rats. RESULTS: All of the rats in the no-resuscitation group were expired before the end of the 6-hour observation period. Survival times were significantly longer in the PSR group than in the RR group (survival rates, 11 of 15 vs. 5 of 15, log rank p = 0.032). Plasma amino alanine transferase, histologic liver injury, and ROS generation in the liver tissue were significantly lower in the PSR group than in the RR group (all findings significant, p < 0.05). In addition, PSR significantly decreased plasma nitric oxide, liver interleukin 1&bgr;, and liver interleukin 6 compared with rapid resuscitation in addition to augmenting Akt survival pathways (all p < 0.05). CONCLUSION: Slow reperfusion by PSR decreased mortality, ROS generation, and liver injury in rats undergoing hemorrhagic shock. Stepwise resuscitation also decreased inflammatory cytokine production and augmented Akt survival pathways.

      • SCISCIESCOPUS

        Genetic effect of <i>CCR3</i> and <i>IL5RA</i> gene polymorphisms on eosinophilia in asthmatic patients

        Lee, June-Hyuk,Chang, Hun Soo,Kim, Ji Hyun,Park, Se-Min,Lee, Yong Mok,Uh, Soo Taek,Rhim, Taiyoun,Chung, Il Yup,Kim, Yong-Hoon,Park, Byung Lae,Park, Choon-Sik,Shin, Hyoung Doo Elsevier 2007 The journal of allergy and clinical immunology Vol.120 No.5

        <P><B>Background</B></P><P>Eosinophilic infiltration and peripheral blood eosinophilia in asthma require the cooperation of eosinophil-specific cytokines and chemokines and their receptors.</P><P><B>Objective</B></P><P>We investigated the association of polymorphisms in <I>CCR3</I> and <I>IL5RA</I> with asthma susceptibility or peripheral blood eosinophilia and the effects of the polymorphisms on receptor expression.</P><P><B>Methods</B></P><P>Polymorphisms in <I>CCR3</I> and <I>IL5RA</I> were identified and genotyped in 576 asthmatic patients and 180 healthy control subjects. CCR3 and IL-5 receptor α (IL-5Rα) protein expression on eosinophils was measured by means of flow cytometry.</P><P><B>Results</B></P><P>Although polymorphisms in <I>CCR3</I> were not associated with asthma susceptibility, the <I>CCR3</I> haplotype <I>ht2</I> showed a negative gene dose effect on the eosinophil count (<I>P</I> = .003–.009). <I>IL5RA c.−5091G>A</I> was weakly associated with eosinophil count. The effects of <I>ht2</I> were greater when paired with <I>IL5RA c.−5091A</I> (<I>P</I> = .001–.002). CCR3 protein expression was higher on eosinophils of asthmatic patients without <I>ht2</I> than in those with <I>ht2</I>. Asthmatic patients with the <I>IL5RA c.−5091A</I> allele showed higher IL-5Rα expression than those who were homozygous for the G allele.</P><P><B>Conclusion</B></P><P>The genetic association between <I>CCR3</I> polymorphisms and the number of circulating eosinophils was revealed as a novel finding. These associations were more pronounced when the <I>CCR3</I> polymorphisms were paired with polymorphisms in <I>IL5RA</I>. The protein expression levels of CCR3 and IL-5Rα on peripheral blood eosinophils are associated with the polymorphisms on their own genes.</P><P><B>Clinical implications</B></P><P>The identification of single nucleotide polymorphisms and haplotypes of <I>CCR3</I> and <I>IL5RA</I> might be useful in developing markers for intermediate phenotypes of eosinophil number and in designing strategies to control diseases related to hypereosinophilia.</P>

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