대구전시컨벤션센터(EXCO) 확장의 필요성과 기대효과

서민교,서동욱,이원복 대구대학교 경제경영연구소 2006 경제경영연구 Vol.4 No.1

Recently, the exhibition and convention industry in many countries, including Korea has rapidly grown. Also the local government recognizes it as a prospective emerging industry and has built exhibition and convention centers to promote its development. Daegu city also has built EXCO(Daegu exhibition & convention center) in 2001 to develop the exhibition and convention industry. The purposes of this study are as follows; 1. To investigate the current situation and performance of EXCO 2. To analyze the necessity and expected effects of EXCO expansion. 3. To search for ideas and suggestions to spur the development of the Daegu-Kyung Buk exhibition and convention industry.

그레이브스 병 치료 후 재발 위험 인자에 관한 연구

이영창,유명희,윤석기,변동원,서교일,김극배 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

연구 배경 : 그레이브스 병에 대한 항갑상선제 치료후 적절한 치료 여부 평가 및 재발 위험성을 예측하기 위하여 여러 가지 예후 판정 인자들이 연구되어 왔으며, 이러한 인자들 중 TRH(thyrotropin-releasing hormone) 자극 시험이 가장 믿을 만한 검사중에 하나로 알려져 있다. 그러나 TRH 자극 검사가 정상으로 나와도 재발하는 경우가 많으며, 현재로는 이러한 경우에 재발을 예측하는 예후 인자에 대한 연구는 전무한 실정이다. 금번 연구에서는 TRH 자극 시험 후 TSH(thyroid stimulating hormone)가 정상적인 반응을 보인 환자를 대상으로 재발 및 관해여부를 예측할 수 있는 인자들을 찾고자 하였다. 대상 및 방법 : 항갑상선제제 치료 종료후 TRH 자극 시험을 시행하였던 그레이브스 병 환자 총 84명 중, 정상적인 TSH 반응을 보이면서 1년 이상 추적 관찰이 가능하였던 32명의 환자를 대상으로 하였다. 처음 진단 시와 치료 종료 시에 T3(triiodothyronine), T4(thyroxine), T3/T4 비, TSH, TRAb, Anti-TPO Ab(anti-thyroperoxidase antibody)를 측정하였으며, 치료 종료 2개월후에는 TRH 자극 검사를 하여 TSH 증가폭(△TSH) 및 유리 T_(3) 증가폭(△FT_(3))을 구하였다. 모든 측정치는 평균±표준편차로 표시하였으며, SPSS software를 이용하여 Student's paired t-test, chi-square test, Wilcoxon signed ranks test를 시행하였고, 유의 수준 0.05 이하를 통계적으로 유의하다고 판단하였다. 결과 1) 총 32명의 환자 중 재발한 환자(Group Ⅰ)는 22명(69%) 이었으며, 재발한 환자(Group Ⅱ)는 10명(31%) 이었다. 2) 진단 초기 총T3 치는 Ⅰ 군에서 342.0±126.2ng/dl, Ⅱ 군에서 493.0 ±142.2 ng/dl로 Ⅱ군에 비해 유의하게 증가되었다(p<0.05). 3) Anti-TPO Ab는 Ⅰ군에서 2.9±4.4, Ⅱ군에서 22.3±22.3 U/mL로 나타나 Ⅱ군에서 유의하게 증가되었다.(p<0.05) 4) 양군에서 치료 종료후 재발시 대부분의 환자가 1년 이내에 재발하였다. 5) TRH 자극· 검사후 유리 T3 증가폭 및 TSH 증가폭은 양군간에 차이가 업ㅅ었다(1.5±0.9 vs 1.2±1.0 pmol/L, 12.54±7.56 vs 11.23±4.21 mU/L, p>0.05) 결론 : TRH 자극 검사후 정상적인 TSH 반응을 보인 환자에서 재발 및 관해여부를 치료 초기 T3 및 치료 종료시 Anti-TPO Ab로 예측할 수 있었으며, 이들 측정치가 증가해 있을수록 재발의 가능성이 많음을 알 수 있었다. 또한 투약 중단후 초기 12개원의 추적기간 동안 관해가 유지되면 그 이후엔 재발의 가능성이 현저히 줄어 들었으며, 이 후 좀더 많은 환자들을 대상으로 하는 장기적인 추적연구가 진행 되어야 할 것으로 사료된다. Background : Many studies were undertaken to find parameters that could predict the clinical course of patients with Graves' disease after withdrawal of antithyroid drugs. In many parameters, TRH (thyrotropin-releasing hormone) stimulation test and T3 suppression test were considered to be one of the most reliable for predicting remission. But recently, some studies showed that the measurement of free T3 and FT3 are to be a more accurate than other thyroid function test. In this study, we measured T_(3), T_(4), T_(3)/T_(4), TSH (thyroid stimulating hormone), TRAb (TSH receptor antibody), FT3 and other known useful parameters to compare the factors influencing the relapse of Graves disease after antithyroid medication. Patients and methods : Among the 84 Graves' disease patients who had done the TRH stimulation test after withdrawal of antithyroid medication, we examined 32 patients who showed normal TSH response and followed up more than one year. T_(3), T_(4), T_(3)/T_(4), TSH and TRAb levels were measured at the time of diagnosis and at the end of therapy. Serum TSH and FT_(3) levels were measured after TRH stimulation, after two months of withdrawal of medication. Statistical evaluation was Performed by SPSS software in combination with Student's Paired t-test, chi-square test, Wlicoxon signed-ranks test. p-value less than 0.05 was considered to be significant. Results 1. In the 32 patients with Graves disease, 10 patients(31%) relapsed(Group Ⅰ) and 22 Patients(69%) remained in remission(Group Ⅱ). 2. Initial serum T3 level was significantly higher in group Ⅰ than group Ⅱ(342.0 ±126.2 vs. 493.0±142.2 ng/dl, p<0.05). 3. Anti-TPO Ab level was significantly higher in group Ⅰ than group Ⅱ(22.3±22.3 vs 2.9±4.4 U/mL, p<0.05). 4. In group Ⅰ and Ⅱ most patients showed relapse within 1 year after antithyroid medication. 5. After TRH stimulation test, serum FT_(3), and TSH level were not significantly different between group I and Ⅱ(p>0.05). 6. Serum T_(4), T_(3)/T_(4), TSH, TRAb levels were not significantly different from group Ⅰ and Ⅱ. Conclusion : In this study, we found increased relapse rate in the patients with Graves' disease whose initial serum T3 and anti-TPO Ab levels were high, so these parameters could be used to predict the relapse of Graves' disease. In the case of more than 12 months remission period after withdrawal of antithyroid medication, no relapse wsa observed in this study, but study should be done in the large population of patients with Graves' disease.

전침 자극에 의한 오디 괄약근 운동성 변화에 관한 연구

이성구,김명완,김홍자,서동환,이상수,김동일,유교상,주연호,민병일,김지훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Background/Aims: This study was designed to evaluated the effects of electroacupuncture on the sphincter of Oddi (SO) motility in humans and to correlate the manometric findings with plasma cholecystokinin (CCK) levels. Methods: Eleven patients (M: F= 5: 6) who had various kinds of biliary disorders were enrolled. SO motility was monitored with a conventional low-compliant continuously perfused technique using ERCP (n=9) or percutaneous transhepatic cholangioscope (n=2). After baseline monitoring for phasic wave contractions of SO, electroacupuncture was applied at a specific acupoint, GB 34, in these 11 patients. A nonspecific acupoint 5 cm away from GB 34 was selected as a control. Manometric parameters of SO were also checked in 6 subjects during stimulation of the control acupoint. CCK plasma levels were measured during the time course of electroacupuncture stimulation. Result: All the manometric parameters including the basal pressure of SO, amplitude, frequency and duration of phasic wave contraction of SO were significantly decreased (p< 0.05) during electroacupuncture stimulation. The inhibition of SO contractility was accompanied by increased CCK plasma levels. After removal of electroacupuncture stimulation, restoration of amplitude and duration to basal condition were noted. A tendency towards the return of SO contractility was also observed in basal pressure and frequency. Stimulation of the control acupoint, however, did not affect the SO contractility and plasma CCK levels. Conclusions: Electroacupuncture stimulation of acupoint GB 34 showed reversible inhibition of SO contraction in humans. We speculate that the response of SO to electroacupuncture stimulation may be mediated by some neurohormonal mechanisms including CCK release. (Korean Journal of Gastrointestinal Motility 2000;6:44-41)

퇴행성 척추질환으로 오인된 척수 종양

조용재,김승범,진동규,서의교,김상진 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

Objectives: Symptoms arising from spinal cord tumor are often insidious in onset and nonspecific in nature. To make the subtle initial signs and symptoms of these tumors more apparent to clinicians, we retrospectively analyzed the data of spinal cord tumor patients who were misdiagnosed as degenerative spine disease. Methods: We reviewed history, symptom, sign, radiological study, and pathologic diagnosis of 19 spinal cord tumor patients who had been operated as degenerative spine disease, especially duration and description of symptoms and sign before an accurate diagnosis was made. Results: Average duration of delay before an accurate diagnosis was made was 178.4 days(range: 23~303). Common symptom and signs on neurologic examination included aggravation of pain(8 cases; 47.1 %), and neurologic decline(9 cases; 52.9%) The misdiagnosis included a herniated lumbar disc(16 cases; 94.1%), lumbar stenosis(1 case; 5.9%). Inappropriate treatment for these misdiagnoses included 5 percutaneous lazer discectomies, 9 discectomies, 3 chemonucleolysis, 2 posterior lumbar interbody fusions with cages. Conclusion: When a patient has symptoms that appear to be out of the ordinary, surgeons should suspect other spinal disease including the spinal cord tumor.

전기 자동차용 아우터 타이로드의 구조설계

서부교(Seo, Bu-Kyo),김종규(Kim, Jong-Kyu),이동진(Lee, Dong-Jin),서선민(Seo, Sun-Min),이권희(Lee, Kwon-Hee),박영철(Park Young Chul) 한국산학기술학회 2013 한국산학기술학회논문지 Vol.14 No.9

아우터 타이로드는 다른 차량 부품에 비해서 중량이 적지만, 차량 성능이 개선됨에 따라 부품의 수 및 중량 에 증가하는 추세에 있다. 그러므로 자동차 연비 향상을 위해서는 경량화가 필수적이다. 따라서 본 연구에서는 전기 자동차용 아우터 타이로드의 경량화 설계를 위한 기초연구로서 구조성능을 검토하기 위한 유한요소해석을 수행하였 다. 개발되는 아우터 타이로드의 재질은 일반 강을 이용하였고 좌굴 및 내구 성능을 검토하였다. 조향계 및 현가계 부품의 개발 시 관성력하중, 충격하중, 좌굴하중 및 내구하중에 의한 강도를 검토하는 것이 일반적이지만, 본 연구에 서는 극악한 하중으로 알려진 좌굴특성과 내구특성 만을 검토하였다. 또한 아우터 타이로드의 단면형상을 결정하는 파라미터를 설계변수로 정의하고 메타모델기반 최적화 기법을 적용하여 최적설계를 제시하였다. 그 결과 초기제품의 중량보다 9 % 감소를 실현하였다. Outer tie rod is lighter than other, but there is the trend item weight and the number is increasing due to vehicle performance improvement. Thus, to improve vehicle fuel efficiency, weight lightening is essential. Therefore, this research performed the finite element analysis to investigate the structural performance of the outer tie rod for an electrical vehicle. This study was performed as the preliminary study for a lightweight design of the outer tie rod. The weight of outer tie rod was optimized by adopting the steel material and applying the trial and error method. The strengths due to durability and buckling should be considered in the structural design of an outer tie rod. Furthermore, the meta model-based optimization was applied to obtain its lightweight design, leading to 9 % weigh reduction.

Condition Monitoring of Lithium Polymer Batteries Based on a Sigma-Point Kalman Filter

Seo, Bo-Hwan,Nguyen, Thanh Hai,Lee, Dong-Choon,Lee, Kyo-Beum,Kim, Jang-Mok The Korean Institute of Power Electronics 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.5

In this paper, a novel scheme for the condition monitoring of lithium polymer batteries is proposed, based on the sigma-point Kalman filter (SPKF) theory. For this, a runtime-based battery model is derived, from which the state-of-charge (SOC) and the capacity of the battery are accurately predicted. By considering the variation of the serial ohmic resistance ($R_o$) in this model, the estimation performance is improved. Furthermore, with the SPKF, the effects of the sensing noise and disturbance can be compensated and the estimation error due to linearization of the nonlinear battery model is decreased. The effectiveness of the proposed method is verified by Matlab/Simulink simulation and experimental results. The results have shown that in the range of a SOC that is higher than 40%, the estimation error is about 1.2% in the simulation and 1.5% in the experiment. In addition, the convergence time in the SPKF algorithm can be as fast as 300 s.

Characteristic Analysis for IPMSM Considering Flux-Linkage Ripple

Dong-Kyun Woo,Sang-Yeop Kwak,Jang-Ho Seo,Hyun-Kyo Jung 대한전기학회 2010 Journal of Electrical Engineering & Technology Vol.5 No.4

In a multi-layer interior permanent magnet synchronous motor, the d- and q-axis parameters vary nonlinearly according to different load conditions, consequently changing the level of saturation. The flux-linkage of d- and q-axis conveys ripple characteristics resulting from mechanical structure and degree of magnetic saturation. If the calculated flux-linkage is correct, the torque using the Maxwell stress tensor method is the same torque calculated by the flux-linkage. However, discrepancy between results exists. In this paper, the d- and q-axis flux-linkage, in consideration of the ripple characteristic, is calculated. Simulation results are then compared with experimental results.

A Wide-Locking-Range Dual Injection-Locked Frequency Divider With an Automatic Frequency Calibration Loop in 65-nm CMOS

Dong-Soo Lee,Jae-Hyung Jang,Hyung-Gu Park,YoungGun Pu,Keum Cheol Hwang,Youngoo Yang,Mun-Kyo Seo,Kang-Yoon Lee IEEE 2015 IEEE Transactions on Circuits and Systems II: Expr Vol. No.

<P>This brief presents a wide-locking-range injection-locked frequency divider (ILFD) that uses an automatic frequency calibration loop. The proposed ILFD uses the ring oscillator to provide the high division ratio with small chip area. A dual-injection scheme is proposed in order to achieve the wide locking range of the ILFD. The free-running frequency of the ILFD is automatically digitally calibrated to reflect the frequency of the injected signal from the voltage-controlled oscillator. To control the frequency of the ILFD, the load current is digitally tuned with 3-bit control signal. The ILFD is fabricated using 65-nm CMOS process, and by tuning the load current, it achieves the wide operation frequency range of 14.1-45.8 GHz. When the input signal of 30 GHz is injected, the locking range of the ILFD is 7.2 GHz, while the power consumption is 2.5 mW from a 1-V supply voltage.</P>

Free Communications : P1 ; Barrier Function and Stratum Corneum Lipids in Non-Lesional Skin of Allergic Contact Dermatitis or Atopic Dermatitis Patients

( Dong Hye Kim ),( Noo Ri Lee ),( Sang Yeon Park ),( Na Young Yoon ),( Kyo Hoon Lee ),( Sunki Kim ),( Chang Seo Park ),( Kwang Hyeon Liu ),( Eung Ho Choi ) 한국피부장벽학회 2014 한국피부장벽학회지 Vol.16 No.2

Lesions of most inflammatory skin diseases, especially atopic dermatitis (AD), present an impaired barrier function and decreased stratum corneum (SC) lipids. We performed this study in order to elucidate that their non-lesional skin also presents subtle changes in the barrier function or the SC lipids. Each 25 patients with AD or allergic contact dermatitis (ACD) as well as 35 healthy control persons were enrolled. For barrier function, basal transepidermal water loss (TEWL) and SC hydration were measured on forehead, inner forearm and calf, and the barrier recovery rate was calculated on the inner forearm. For SC lipid analysis, tapes stripped from the inner forearm were analyzed by HPTLC for total lipids and LC-MS/MS for ceramides. Basal TEWL on non-lesional skin of AD or ACD patients showed no difference. SC hydration decreased significantly in AD patients but not in ACD. Barrier recovery of AD or ACD patients was delayed than healthy control. Non-lesional skin of ACD patients as well as AD showed a decrease of total ceramides content as well as each type of ceramides. Collectively, the non-lesional skin of AD or ACD patients presented a subtle change in barrier function and a decrease of SC ceramides. Therefore, we could recommend a moisturizer containing ceramides and humectants for AD patients and a moisturizer containing ceramides for ACD patients in a concept of tailor-made moisturizer.

열안정성 기공구조를 가진 코디어라이트의 제조

서신석,김동표,문교태,노재성 忠南大學校 産業技術硏究所 1997 산업기술연구논문집 Vol.12 No.1

Cordierite ceramic was prepared by sol-gel method. It was analyzed by Infrared spectroscopy and X-ray diffraction patterns that the ceramic was chemically mixed in molecular level and transformed to α-cordierite at 1250℃. Water vapour treatments for aging and drying process were conducted to get porous cordierite with thermally stable pore structure. It resulted in 220-410㎡/g BET surface area and mesoporous structure with mean pore diameter, 40Å. Compared to naturally dried ceramic, the ceramic showed superior thermal stability of surface area up to 700℃.