부비동 환기의 연구를 위한 인체 비부비동 모형

정용수,김상렬,김동환,정동근,최순섭,정인호,서세훈 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.9

알코올 의존 환자에서의 혈청 성호르몬, 성선자극호르몬, 코티졸 및 프로락틴

서동수,박두병,이길홍 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.3

목 적 : 알코올 의존 환자들에서 흔히 보이는 성기능장애는 신경병적 요인과 사회심리학적 요인을 배제할 수는 없지만 내분비 기능의 이상에 의해 기인하는 것으로 알려져왔다. 이러한 내분비 이상을 밝히는 예비적 단계로써 알코올 의존 환자에서 성호르몬, 성선 자극 호르몬, 코티졸과 프로락틴을 살펴보고자 본 연구를 시행하였다. 방 법 : 알코올 의존을 가진 15명의 환자군에서 금단중과 금주후 21일 후에 시상하부-뇌하수체-성선축 호르몬(테스토스테론, 에스트라디올, 황체화 호르몬, 난포자극 호르몬)을 검사하였으며, 이축에 영향을 미칠 수 있는 코티졸 프로락틴도 포함시켰다. 그리고 12명의 건강 대조군에서 동일한 검사를 시행하여 그 결과를 환자군과 비교하였다. 결 과 : 금단중에 황체화 호르몬, 에스트라디올, 코디졸, 프로락틴은 의미있게 상승되었고 이들 호르몬 중 황체화 호르몬과 프로락틴은 금주후 3주뒤에도 여전히 상승되어있었다. 결 론 : 본 연구 결과 간경화가 없는 만성 알코올 의존 환자들은 정상범위에 테스토스테론 농도를 유지하는 것으로 보여진다. 이에비해 에스트로젠과 프로락틴 농도는 뚜렷하게 상승되는 것으로 보이며 이들 호르몬의 상승이 성기능장애를 포함한 만성 알코올 환자들의 여러 가지 임상증상들과 관련이 있는지에 대한 연구가 추후에 이루어져야될 것으로 생각된다. Objective : Sexual dysfunction has been frequently experienced by male alcoholics. The possible etiologies of the sexual problems in alcoholics has been known to be hormonal rather than neuropathic or psychosocial. The main purpose of our study was, therefore, to examine the different parameters of the hypothalamic-pituitary-gonadal axis(testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone : HPG axis) in chronic alcoholic men. On the other hand, cortisol and prolactin were included because they could influence the HPG axis. Methods : Serum concentrations of testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone, cortisol, and prolactin were measured in 15 male patients with alcohol dependence once during withdrawal and once after 21 days of abstinence. The results were compared with those of 12 healthy male volunteers. Results : During withdrawal, luteinizing hormone, estradiol, cortisol and prolactin levels were significantly enhanced. Estradiol and cortisol concentrations fell significantly during abstinence, whereas luteinizing hormone and prolactin concentrations remained elevated. Conclusions : These results suggest that normal serum concentrations of testosterone were maintained in alcoholic men without hepatic cirrhosis. In contrast to this. estrogen and prolactin concentrations seemed to be markedly enhanced. Whether this increase in estrogen and prolactin concentrations is implicated in difference clinical and psychological symptoms seen in chronic alcoholics remains to be investigated.

Amiodarone 投與에 의한 肝의 燐脂質症

김동훈,장금미,서인수,손태중 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.1

관광호텔 프런트근무자의 객실판매기법에 관한 연구

서동수 문화관광연구학회 2001 문화관광연구 Vol.3 No.3

How to assign and sale the room have influence on hotel image, room management, room sales ratio and guest satisfaction. The purpose of this study is to present how to assign and sale the room to beginner room assign and sale is classified as follows. 1) when making a reservation - Check the room type on day - Pre-assign the room for the special guest. 2) when to check in - Classfy the nationality, purpose of visit, tour type(F.I.T or Group) - Check the payment and check out date. 3) while staying - Classfied by extention and room changes - check the pre-assig room and floor which is blocked effective room assignment have Influence on management benefits and guest satisfaction. therefore, it's necessary for novice to have a train for room sales.

비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

고관절 전 치환 성형술 후 탈구에 관한 치험 및 연구

서유성,김동진,박종석,임수재,나수균,최창욱 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Dislocation is one of the serious complications in total hip replacement arthroplasties. The purpose of this study is to evaluate the risk factors of dislocation, including age, sex, preoperative diagnosis and bilaterality, history of previous hip surgery, positioning of component, soft tissue tension, treatment after dislocation or redislocation. Authors reviewed 190 patients of total hip replacement arthroplasty, which were performed from Jan. 1990 to Dec. 1996. 15 cases developed dislocation after surgery. Incidence of dislocation was 7.89%(15 of 190 cases). Dislocation after revision was not happened(0 of 18 cases). Inclination of acetabular cup was average 37.5° (range: 31° - 43° ). Average anteversion of the acetabular component was 18.1" by Woo and Morrey method, 11.4° by Hassan method. They were normal range except 3 cases. Dislocation was not prevented even though inclination and anteversion of acetabular cup were within normal range. Soft tissue tension is determined by change of limb and femoral neck length. Average limb length difference was -0.2mm(range; -l0mm - +10mm) and average offset difference was +1.7mm(range;-4mm - +18mm). Revision must be accomplished as soon as possible when limb shortening happen by upward migration of the acetabular component. In conclusion, anteversion of acetabular cup may be most important factor in our cases, so cup position must be fixed in proper position during operation.

자궁경부 세포진 검사에서 비정형 선세포의 임상병리학적 중요성

서동수,윤만수,최경운 부산대학교 병원 암연구소 2009 부산대병원학술지 Vol.- No.25

Al_2O_3를 함유한 Poly(ε-caprolactone)/Poly(ethylene oxide) 마이크로캡슐의 향오일 방출거동

박수진,양영준,이재락,서동학 한국공업화학회 2003 공업화학 Vol.14 No.3

본 실험에서는 소수성의 PCL과 친수성의 PEO의 함량비를 변화시키면서 액증건조법을 이용하여 향오일이 흡착된 Al_2O_3를 심물질로 함유하는 마이크로캡슐을 제조하였다. 또한, Al_2O_3의 화학적 처리가 마이크로캡슐의 향오일 방출거동에 미치는 영향을 고찰해 보았으며, 산-염기 표면처리 용액으로서 30 wt% HCL(Al_2O_3 -HCl)과 30 wt% NaOH(Al_2O_3 -NaOH) 용액을 각각 사용하였다. 처리 전후의 Al_2O_3의 표면 산-염기도는 Boehm 선택 중화법을 이용하여 측정하였다. PEO의 함량에 따른 마이크로캡슐의 형태는 image analyzer와 scanning electron microscope (SEM)을 통하여 관찰하였다. FT-IR 측정을 통하여 심물질이 함입되었음을 확인하였으며, 또한 접촉각 측정을 통하여 표면 자유에너지의 변화를 알아보았다. 그 결과, PCL/PEO 마이크로캡슐의 직경, 표면 자유에너지 그리고 향오일의 방출속도는 PEO의 함량이 증가할수록 증가하였다. 또한 Al_2O_3-HCL을 함유한 PCL 마이크로캡슐의 향오일 방출속도는 감소하였는데, 이는 PCL/PEO 마이크로캡슐의 친수성의 증가와 산-염기 반응에 의해 물리화학적으로 Al_2O_3와 향오일간의 분자간 인력이 증가하였기 때문이라 사료된다. In this work biodegradable polymers of hydrophobic poly(ε-caprolactone) (PCL) and hydrophilic poly(ethylene oxide) (PEO) were prepared in different weight ratios, 100 : 0, 90 : 10, 80 : 20, and 70 : 30, to manufacture the microcapsules containing Al_2O_3 and fragrant oil by an oil-in-water (o/w) emulsion solvent evaporation method. The release behaviors of microcapsules were studied by chemical treatments of Al_2O_3 with 30 wt% HCl and Al_2O_3 with 30 wt% NaOH. The acid and base values were investigated with the Boehm's titration technique. The effect of PEO content on the diameter and shape of microcapsules were observed with image analyzer and scanning electron microscope (SEM). PCL/PEO microcapsules containing flagrant oil were confirmed by FT~IR. The variation of surface free energy of the microcapsules characterized by contact angles was examined in terms of PEO ratio in the blending system. As a result, it was found that the diameter, surface free energy, and fragrant oil release rate of PCL/PEO microcapsules increased with increasing the PEO ratio. However, the fragrant oil release rate of PCL microcapsules containing Al_2O_3-HCl decreased. These results were mainly due to the increased hydrophilicity of the microcapsules or the acid-base interfacial interactions between Al_2O_3-HCL and fragrant oil.

양극산화된 탄소섬유/에폭시 복합재료의 크랙저항 특성

박수진,오진석,서동학 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.1

본 실험에서는, 양극산화 처리된 탄소섬유의 표면 변화가 탄소섬유 강화 에폭시 복합재료의 크랙저항 특성에 미치는 영향에 대하여 고찰하였다. 탄소섬유의 표면처리 전후 표면특성 변화는 산-염기도, FTR-IR, XPS 그리고 접촉각 측정을 통하여 알아보았고, 복합재료의 크랙저항 특성은 임계에너지 방출 속도 Ⅰ(critical energy rate, G_(Ic))와 임계에너지 방출 속도 Ⅱ(critical energy rate mode Ⅱ, G_(IIc))의 두 가지 방법을 통하여 고찰하였다. 실험결과, 탄소섬유 표면의 표면 산도와 O_(IS)/C_(IS) 비율이 증가하였는데, 이는 탄소섬유의 산성관능기와 표면자유에너지의 극성요소 증가에 기인하는 것으로 판단된다. 복합재료의 G_(Ic)그리고 G_(IIc)같은 기계적 계면성질은 탄소섬유의 양극산화로 향상되어졌는데, 이는 산성관능기들의 증가에 따른 탄소섬유와 매트릭스와의 계면 결합력의 증가에 기인하는 것으로 판단된다. Anodic oxidation on the surfaces of carbon fibers was carried out to enhance the mechanical interfacial properties of carbon fibers-reinforced epoxy matrix composites. And the surface characteristics of untreated and treated carbon fibers were studied by FT-IR, XPS, and contact angle measurements after modifications. Crack resistance of the composites was investigated using by two types of testing method, namely critical energy release rate mode Ⅰ(G_(ⅠC)) and mode Ⅱ(G_(ⅡC)). The O_(IS)/C_(IS) ratio of the carbon fibers was increased after anodic treatment, due to the introductions of the oxygen-containing functional groups, or the specific components of surface free energy of the carbon fibers. It was found that the mechanical properties at interfaces, including G_(ⅠC) and G_(ⅡC) of the composites had been improved by the oxidation, which could probably be attributed to the increase of the degree of adhesion at interfaces between fibers and resin matrix in the composite system.

표면처리된 탄화규소의 첨가가 탄소섬유 강화 복합재료의 열안정성 및 기계적 특성에 미치는 영향

박수진,오진석,서동학 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.5

본 연구에서는 표면처리에 따른 탄화규소(SiC)의 표면특성변화가 탄소섬유 강화 복합재료의 열안정성과 기계적 물성에 미치는 영향을 조사하였다. 표면처리된 탄화규소의 표면특성은 산·염기도, 접촉각측정 그리고 FT-IR을 통하여 알아보았으며, 열안정성은 TGA를 이용하여 조사하였다. 탄소섬유 강화 복합재료의 기계적물성은 interlaminar shear strength(ILSS) 그리고 critical strain energy release rate mode Ⅱ(G_(IIC))를 통하여 고찰하였다. 실험결과 산 처리된 SiC(A-SiC)와 오존처리된 SiC(0-SiC)는 미처리된 SiC(V-SiC)나 염기 처리된 SiC(B-SiC)에 비하여 산도가 증가하였고, 접촉각 측정 결과, 산성 용액과 오존 표면처리는 극성요소의 증가에 기인하는 SiC의 표면자유에너지를 증가시켰다. ILSS과 G_(IIC) 같은 기계적 계면 성질은 A-SiC와 O-SiC로 향상되어졌는데, 이러한 결과는 좋은 젖음성이 최종 복합재료의 SiC와 에폭시 수지 매트릭스 사이의 계면결합력을 증가시키는 중요한 역할을 하기 때문으로 판단된다. In this work, the effect of chemically wet and dry treatments of SiC was investigated in mechanical interfacial properties of carbon fibers-reinforced composites. The surface properties of Sic were determined by acid/base values, contact angles, and FT-IR analyses. The thermal stabilities of the carbon fibers-reinforced composites were investigated by thermo-gravimetric analysis (TGA). Also, the mechanical interfacial properties of the composites were studied in interlaminar shear strength (ILSS) and critical strain energy release rate mode Ⅱ(G_(ⅡC)) measurements. As a result, the acidically treated SiC (A-Sic) and ozone treated (0-Sic) had higher acid value than that of untreated Sic (V-Sic) or basically treated Sic (B-Sic). According to the contact angle measurements, it was observed that acidic solution and ozone treatments led to an increase of surface free energy of the SIC surfaces, mainly due to the increase of the specific (polar) component. The mechanical interfacial properties of the composites, including ILSS and G_(ⅡC) had been improved in the specimens treated by acidic solutions and ozone gas. These results were explained that good wetting played an iniportant role in improving the degree of adhesion at interfaces between SiC and epoxy resin matrix in a composite system