국내 다기관에서 조사한 지역사회획득 메티실린내성 황색포도알균의 빈도와 임상적 특성

송진수,최평균,송경호,조재현,김성한,방지환,이창섭,박경화,박경운,신수,최희정,김의석,김동민,이미숙,박완범,김남중,오명돈,김의종,김홍빈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

목적 : 최근 전세계적으로 지역사회획득 메티실린내성 황색포도알균(community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA)의 보고가 증가하고 있다. 하지만, 우리나라에서는 CA-MRSA 감염증에 대한 증례보고만 있을 뿐 아직까지 체계적인 연구결과가 없는 실정이다. 저자들은 국내에서 CA-MRSA의 빈도, 감염증의 임상적 양상, 분리된 균주의 항균제내성 양상을 조사하였다. 재료 및 방법 : 2005년 1월부터 2005년 6월까지 7개 병원에서 MRSA가 분리된 환자의 명단을 파악한 후 의무기록지와 건강보험심사평가원의 자료를 검토하였다. 외래나 응급실에서 혹은 입원 후 72시간 이내에 균주가 분리되고 MRSA 획득과 관련된 위험인자가 없는 경우 CA-MRSA로 정의하였으며, 분리된 균주의 임상적 의미에 따라 원인병원체(pathogen), 집락화(colonizer), 미결정(undetermined)으로 분류하였다. Penicillin과 oxacillin을 제외하고 3개 이상의 다른 계열 항균제에 내성이면 다제내성으로 정의하였다. 결과 : 연구기간동안 총 3,251주의 황색포도알균이 분리되었으며, 이 중 MRSA는 1,900주(58.4%)였다. MRSA 가운데 CA-MRSA는 114주(6.0%) 였으며, 이들이 분리된 부위는 귀(62주), 비뇨기계(14주), 피부 및 연부조직(11주), 호흡기계(10주), 혈액(3주) 등이었다. CA-MRSA 균주 가운데 집락균은 22주, 원인병원체는 22주였으며, 나머지 균주에 대해서는 그 임상적 의미를 결정할 수 없었다. 항균제 감수성 검사를 시행한 73균주 중 47주(64.4%)는 다제내성이었다. CA-MRSA 감염증 22예 중 피부 및 연부조직 감염(9예)과 중이염/외이도염(9예)이 가장 흔하였다. 침습적 감염증(invasive infection)은 4명(원발성 균혈증 3예, 감염성 관절염 1예)에서 확인되었지만, CA-MRSA 감염증으로 사망한 환자는 없었다. 결론 : 병원내 감염증에서는 MRSA가 심각한 문제이지만, 아직까지 지역사회 감염증에서 CA-MRSA는 흔하지 않았다. Background : Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. In Korea, little is known about the epidemiology and clinical features of community-associated MRSA (CA-MRSA). Material and Methods : Clinical microbiology laboratory databases of 7 hospitals were reviewed to identify the patients from whom MRSA was isolated during the period of January to July 2005. Only one isolate per patient was enrolled. In order to identify the risk factors of MRSA acquisition, the medical records and the Health Insurance Review Agency databases were reviewed. CA-MRSA was defined as MRSA isolated from patient without established risk factors. We analyzed patient demographics, underlying medical conditions, characteristics of infection, and antimicrobial susceptibility profiles. Results : Of total 3,251 S. aureus isolates, 1900 (58.4%) were MRSAs. Of the MRSA isolates, 114 (6.0%) were CA-MRSA. Of 114 CA-MRSA isolates, 22 (19.3%) were colonizers, 22 (19.3%) were pathogens, and the clinical significance of remaining 70 (61.4%) could not be determined. Median age of the 22 patients with CA-MRSA disease was 47 years. Nine patients had skin and soft tissue infections, 9 ear infections, 3 bacteremia, 1 septic arthritis. Seven patients had underlying medical disease. None died of the CA-MRSA infections. Of the 73 isolates of CA-MRSA, 47 (64.4%) were resistant to more than 3 classes of antibiotics besides β-lactams. Conclusion : Although MRSA is highly prevalent among hospital-associated S. aureus infection, CA-MRSA infections are not common.

KC80196을 이용한 Profibus Interface Card 구현

송동섭,신동렬 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1

Due to the advances in data communication and hardware technology, many centralized control systems have been replaced by distributed digital systems. Fieldbuses are low level industrial networks and are currently undergoing enormous revolution. Industries have recently observed lots of applications using fieldbus networks. Profibus is one of fieldbus currently available. In this paper we describe the interface between the applications and the Profibus network and then implement an interface card on DIN 19 245 Profibus Standard. We show that this implementation is a useful technique of converting serial communication to intelligent polling network as well as the efficient and simple design.

PMSM의 저속운전 및 기동성능 개선을 위한 선형 엔코더

이동희,송달섭,원태현 동의공업대학 2001 論文集 Vol.27 No.1

PMSM(Permanent Magnet Synchronous Motor) drives are widely used in the industrial applications and home appliances because of high torque ratio, high efficiency and precise control performance. In recent years there has been a significant development of PMSM motors of various kinds. Improvements in the properties of permanent magnet materials have increased the viability of related types of motors. However, precise speed and position information is essential for the good control performance. In order to produce correct torque, the rotor flux position information from position sensor has to be identified. In this paper, a low cost position sensor is proposed for improving of starting and low speed performance of PMSM. The proposed position sensor produces a linear analog signal that is proportional to the electrical rotor position. The information of initial rotor position at the starting instance and accurate position in the low speed can be obtained with the proposed encoder. The performance of the proposed encoder is verified with experimental results.

자속 분포학습에 의한 영구자석 동기전동기의 토오크 리플 저감

이동희,송달섭,원태현 동의공업대학 2001 論文集 Vol.27 No.1

PMSM drives are widely used in the industrial and residential applications because of high efficiency, high power density and high performance. For better performance of PMSM, however, torque ripples should be reduced. This paper investigates a reduction of torque ripple due to the unsinusoidal flux linkage produced by the shapes of stator slot and magnetic pole. To minimize torque ripple, a simple flux estimator is proposed. This method interactively compensates the distributed flux linkage from an error between the measured and estimated currents. The proposed algorithm is verified through simulation.

글로우 방전을 이용한 이산화탄소의 전환특성

신용섭,송승훈,곽동주 慶星大學校 1998 論文集 Vol.19 No.2

In this study, the characteristics of CO₂conversion and glow discharge were investigated using glow discharge plasma reactor with a parallel copper electrode system. A pure CO₂ gas was used for the carrier gas under gas pressure of 10∼80 torr in a glow discharge. For glow discharge, discharge current was increased with the increase of discharge voltage. In the case of constant discharge voltage, the discharge current tend to increase with the decreasing of gas pressure. Using pure CO₂only, the CO₂conversion was increased with the increase of discharge power and the decreased of gas pressure. The maximum CO₂ conversion was 28% at 10 torr, 598 W, 902.4V. Energy yield was decreased with the increase of discharge power and discharge voltage. Also, the concentrations of CO₂and O₂in the produced gas were slightly increased with the increase of CO₂ conversion.

오존 발생기용 전원장치 개발 및 특성에 관한 연구

김동희,이달해,성현직,오승훈,이봉섭,배상준 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.1

The power semiconductor switching devices(PSSD) continuously developed, Power Electronic Technology using PSSD is gradually extended. The high frequency inverter to generate the large power high frequency subject to power electronic technology pursuit various application. Also, in emboss with environmental destruction problem cause the atmosphere and the water pollution to growth of the commercial society, the research in favor of cleansing environmental a pollutant actively proceed. Cause of having a strong oxygenization in the physical world, the ozone has sterillization effect predominantly against virus, bacteria, etc and has application in decolorization, deodorization, food storage and air cleansing and has a merit that does not cause the secondary pollution by being restored to oxygen lastly. Therefore, This project describe study on the ozone generation power supply using the high frequency electric field method and the lamp type ozone generator using photochemistry, one of method of generate ozone.

트레드밀 운동시 흡기근 테이핑이 폐활량에 미치는 영향

김민지,신수영,송월섭,조수진,최동락,황미진,황진규,박진현,김경,Dennis W. Fell 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

이 연구는 트레드밀 운동과 키네시오 테이핑의 효과에 따른 폐활량의 변화를 알아보기 위해 26명의 비흡연자가 참가하였으며 키네시오 테이핑을 적용하지 않은 그룹과 키네시오 테이핑을 적용한 두 그룹으로 무작위로 배정하고 각 군들을 주 3회 6주간의 트레드밀 훈련을 실시하였다. 실험 전과 후, 스파이로미터를 사용하여 키네시오 테이핑의 적용 따른 폐활량 변화 효과를 측정하였다. 이 연구의 결과를 종합해보면 키네시오 테이핑을 적용 그룹에서 적용하지 않은 그룹에 비해 FVC, FEV1에서 유의한 증가를 보였다. 이러한 결과는 건강한 성인에서 키네시오 테이핑을 적용한 경우 키네시오 테이핑을 적용하지 않고 트레드밀 운동을 한 경우보다 폐활량의 향상에 효과적이라고 생각되어진다. The purpose of this study was to investigate the variation of vital capacity(VC) according to the effects of kinesio taping with treadmill exercise. Twenty-six non-smokers were participated in this research and these subjects were randomly assigned into two groups. To measure the VC variation effects of kinesio taping, spirometer was used. The collected data were analyzed statistically by using a paired Mauchly test and repeated measure ANOVA. The results of this study were as follows; A group: treadmill with kinesio taping B group: treadmill without kinesio taping. Between A and B, there were significant differences. In the case of A group, there was 11.66% increase of VC, during 3 weeks experiment(p<.01). In the case of B group, there were significant differences, 3.35% increase of VC, during 3 weeks taping intervention(p<.01). After 6 weeks experiment, the improvement of VC shown a significant difference with intergroup (p<.05). From this result, it was revealed that treadmill exercise with kinesio taping was effective to improve VC to healthy adult than treadmill exercise without kinesio taping.

한국판 소아 양극성장애 설문지 2.0(Child Bipolar Questionnaire 2.0)의 신뢰도 및 타당도 연구

천근아,신동원,김보라,소윤섭,전진용,송동호 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.3

Objectives : The Child Bipolar Questionnaire 2.0 (CBQ 2.0) is a rapid screener with a Core Index subscale of symptom dimensions frequently reported in childhood-onset bipolar disorder (BD) and scoring algorithms for DSM-Ⅳ BD, with and without ADHD, and the proposed Narrow, Broad, and Core phenotypes. This report provides preliminary data on the reliability and validity of the CBQ 2.0-Korean version. Methods : Core Index subscale to effectively predict diagnostic classification by structured interview was assessed using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version (K-SADS-PL-K). Test-retest and inter-rater reliabilities of the CBQ 2.0 were assessed. Correlation of Korean Child Behavior Checklist (K-CBCL) with CBQ 2.0-Korean version was performed. Results : The CBQ 2.0 screening algorithms performed with a specificity of 66.7% and a sensitivity of 94.7% in classifying subjects with K-SADS-PL-K diagnosis of BD vs. no BD. The Core Index subscale had “good” agreement with K-SADS-PL-K diagnosis (Kappa=0.676) in identifying BD, ADHD-only, and no diagnosis. Conclusion : This preliminary data is from a sample derived from the child and adolescent psychiatric clinics, further validation is needed with community based samples in which childhood-onset BD is rarer and diagnoses more diverse. The CBQ 2.0-Korean version shows potential for rapid and economically feasible identification of possible childhood-onset BD cases as defined by DSM-Ⅳ criteria as well as by alternate disease phenotypes.

Long-term outcomes in children with glioblastoma

Song, Kyung Sun,Phi, Ji Hoon,Cho, Byung-Kyu,Wang, Kyu-Chang,Lee, Ji Yeoun,Kim, Dong Gyu,Kim, Il Han,Ahn, Hyo Seop,Park, Sung-Hye,Kim, Seung-Ki Journal of Neurosurgery Publishing Group 2010 Journal of Neurosurgery: Pediatrics Vol.6 No.2

<B>Object</B><P>Glioblastoma is the most common primary malignant brain tumor; however, glioblastoma in children is less common than in adults, and little is known about its clinical outcome in children. The authors evaluated the long-term outcome of glioblastoma in children.</P><B>Methods</B><P>Twenty-seven children were confirmed to have harbored a glioblastoma between 1985 and 2007. The clinical features and treatment outcomes were reviewed retrospectively. All patients underwent resection; complete resection was performed in 12 patients (44%), subtotal resection in 12 patients (44%), and biopsy in 3 patients (11%). Twenty-four patients (89%) had radiation therapy, and 14 (52%) patients received chemotherapy plus radiation therapy. Among the latter, 5 patients had radiation therapy concurrent with temozolomide chemotherapy. Four patients with small-size recurrent glioblastoma received stereotactic radiosurgery.</P><B>Results</B><P>The median overall survival (OS) was 43 months, and the median progression-free survival was 12 months. The OS rate was 67% at 1 year, 52% at 2 years, and 40% at 5 years. The median OS was significantly associated with tumor location (52 months for superficially located tumors vs 7 months for deeply located tumors; p = 0.017) and extent of removal (106 months for completely resected tumors vs 11 months for incompletely resected tumors; p < 0.0001).</P><B>Conclusions</B><P>The prognosis of glioblastoma is better in children than in adults. Radical resection followed by concurrent chemoradiation therapy may be the initial treatment of choice.</P>

Hardness and microstructure of interstitial free steels in the early stage of high-pressure torsion

Song, Yuepeng,Wang, Wenke,Gao, Dongsheng,Yoon, Eun Yoo,Lee, Dong Jun,Lee, Chong Soo,Kim, Hyoung Seop Springer-Verlag 2013 JOURNAL OF MATERIALS SCIENCE - Vol.48 No.13