LT, Others : PE-133 ; A case of hepatic hemangioma appearing atypical finding confirmed by dynamic MRI in patients with high risk of hepatocellular carcinoma

( Dong Won Park1 ),( Soo Hyung Ryu1 ),( Myung Ki Oh ),( Seong Yeon Jeong ),( Kyeong Sam Ok ),( Jae Chan Shim ),( Jin Nam Kim ),( You Sun Kim ),( Jeong Seop Moon ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-

Background: Hemangioma is the most common benign hepatic tumor. Many hepatic hemangiomas tend to be found incidentally, but should be differentiated from malignant tumors. We report an interesting case of hepatic hemangioma in patient who has high risks of hepatocellular carcinoma. Case: A 52-year-old woman, who was a chronic alcoholic abuser and hepatitis C virus carrier with no treatment experience, was admitted due to diarrhea. The patient had suffered from intermittent abdominal pain in the right subcostal area for recent 3 months. Also the patient had easy bruising and frequent epistaxis. She had used oral contraceptives for almost 20 years. Systolic blood pressure was 160 mmHg and diastolic blood pressure was 80 mmHg. Body temperature was normal. Physical examination revealed icteric sclerae and tenderness in right upper quadrant of the abdomen. Laboratory study showed platelet count of 31,000/ul, AST/ALT of 302/127 IU/L, and total bilirubin of 2.7 mg/dl. 3-phased contrast-enhanced abdominal computed tomography (CT) revealed a 4 cm × 4 cm sized hepatic mass involving both segment 5 and 6. Abdominal CT finding suggested hepatic hemangioma, however, typical finding of hemagioma was unclear, therefore, could not rule out the malignancy. Since she had risk factors for hepatocellular carcinoma, abdominal ultrasonography was performed for further evaluation. But abdominal ultrasonography also showed atypical finding. The confirmative diagnosis could be done by dynamic magnetic resonance imaging (MRI) using primovist®, which is an innovative liver cell-specific contrast medium. Dynamic MRI presented peripheral globular enhancement and a centripetal fill-in pattern, confirmatory findings of hepatic hemangioma, on the delayed image. The patient got relief from abdominal pain and diarrhea during admission, now is being followed-up at a general out-patient clinics. Conclusions: Hemangiomas with atypical abdominal CT and ultrasonographic findings in patients with high risks of hepatocellular carcinoma can be easily characterized with primovist-enhanced dynamic MRI.

다목적홀의 음향설계를 위한 1/10 축척모형의 제작 및 평가

류종관,신동재,전진용 대한건축학회 2004 대한건축학회논문집 Vol.20 No.9

A 1/10 scale model was introduced as an efficient tool to predict acoustical qualities of multi-purpose halls It was constructed to predict the acoustical properties, and to complement and adjust the architectural components on room acoustical characteristics of K-performing arts center The materials of scale model such as seats and audiences, absorption banners were selected through measurements of absorption coefficient In a 1/10 reverberation chamber and the absorption coefficients due to air-absorption With relative humidity was also Investigated As a result, It showed that types and parts of material and arrangement of specimen had much effects on absorption coefficient, and air absorption resulted In a significant decrease In absorption coefficient at high frequency In addition, the reverberation time of scale model was measured In occupied seats and the effect of absorption banners on the ceiling and side walls was also investigated Results showed that reverberation time of scale model showed a decrease of 0.5s by banners on the ceiling, whereas those on side walls had a little effect on reverberation time

참돌꽃 근경의 항산화작용

류광열,강원식,김영호,장해동,홍진태,유환수,윤여표 충남대학교 약학대학 의약품개발연구소 1998 藥學論文集 Vol.14 No.-

The purpose of this study was to determine the antioxidative effects of Rhodiola sachalinensis Rhodiola methanol extract was fractionated sequentially with dichloromethane and butanol. Each Rhodiola fraction (water, MeOH, BuOH and CH_2Cl_2 fractions) showed the potent superoxide dismutase (SOD) activity, and had inhibitory effets on peroxide value of linoleic acid (40~57%) and lipid peroxidation (47~70%) in FE^2+/ascorbate system-induced rat liver microsome. Rhodiola methanol extract also recovered carbon tetrachloride-induced decrease in SOD by 42% and catalase activities by 50%, and had inhibitory effects (54%) on carbon tetrachloride-induced lipid peroxidation in rat liver microsome. These results suggest that Rhodiola sachalinensis has the antioxidative effects.

관절성형술 및 측두근막 이식술을 이용한 악관절 강직증의 치험례

진택현,오승환,류동목,김여갑,이상철 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

This is a case of bony ankylosis of right temporomandibular joint with mild facial asymmetry resulted from trauma, which bring about the right condylar fracture, and corrected by interpositional arthroplasty with temporal fascia flap and coronoidectomy. The postoperative results were functionally and esthetically good, but continued osbervation is necessary to evaluation of abnormal bony growth and reankylosis.

한국인의 치과의원 내원요인 조사 연구

류영욱,배현숙,성진효,김동기 조선대학교 구강생물학연구소 2003 Oral Biology Research (Oral Biol Res) Vol.27 No.1

According to the increase of the number of dental clinics and the level of the patient's recognition about oral health care, the need for effective clinical management to provide proper oral health care service to the patients has arisen. Many patients has selected the dental clinics based on self estimation or other recommendation. Therefore the main reasons for selecting the dental clinic by the patients needed to analyze, So we conducted the survey which prepared questionnaire were provided to 700 subjects and collected data related to the factors for patients to select the dental clinics. The results were as follows : 1. In the view of access, the place easy of access and parking capacity was important to the degree of 43.0% and 30.8%, respectively. 2. In relation to the dentist, the quality of treatment and the trust was important to the degree of 80.7% and 71.3%, respectively. 3. Modern clinical facility was occupied 65.5% in the basic environment factors. 4. In the basic factors, kindness and cleanliness was 76.6% and 76.7%, respectively, and it showed that these factors were more important than the number of the clinicians and comfort of the waiting room. 5. In relation to the satisfaction of treatment, cheaper treatment cost, decreased waiting tine, the variety of treatment tine and various payment method were important to the degree of 51.8%, 48.4%, 42.8% and 39% in order.

화천의 저서성 대형무척추동물의 군집구조에 관한 연구

류성만,정동기,이종욱,차진열 嶺南大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.17 No.-

The present study was conducted to determine the community structure in Hoe Stream based on the benthic macroinvertebrates. The survey area included nine sites in Hoe stream and two sites in Nakdong river. The study was carried out from March of 1995 to February of 1996. The result are as follows; (1) Benthic macroinvertebrates are composed of a total 200 species including 115 genera, 68 families, 21 orders, 7 classes in five phyla. 2) Average number of individuals was 1353.9/0.5㎡ in the whole study area. Individual number was variable from 10.2/0.5㎡ at the site 10 to 186.3/0.5㎡ at the site 4. Taxa with highest individual species frequency were aquatic insects. 3) Average dominance(DI), species richness(RI), species diversity(H'), and evenness(EI) were 0.62, 1.70, 3.12 and 0.048, respectively, in the whole study area. The biotic indices in Hoe river were relative higher than that of Nakdong river. 4) Functional feeding groups were collector at site 1 to 6, collector and predator at site 7 to 9, filterer and predator at site 10 and 11.

N/O/N 박막 다이아프레임을 이용한 광섬유 압력센서의 제작 및 그 압력특성

유양욱,김명규,박동수,김창원,김진섭,이정희,손병기 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

The 0.6 μm N/O/N triple layer, Si_(3)N_(4)(150 nm)/SiO_(2)(300 nm)/Si_(3)N_(4)(150 nm), was deposited on silicon substrate and the N/O/N thin film diaphragm was formed using anisotropic etching technique. The stress of the formed diaphragm was very small with temperature variations. Combining this diaphragm and the optical fiber, intensity-type pressure sensor was fabricated and its pressure characteristics were investigated. The relation between the optical output power, inversely proportional to the deflection of the diaphragm, and the applied pressure was almost linear in 0~77 torr range.

유방암 환자에서 bcl-2 단백 발현의 예후 인자로서의 의의

류진우,박종권,정민,박동국,김정택,이두선,이찬영,전호진 단국대학교 1998 論文集 Vol.32 No.-

Breast cancer in women pose a problem, and it can be difficult at times to evaluate the possibility of the cancer recurrence in node negative early cancer. The reliable prognostic markers are needed in breast cancer management to help clinicians identify the patient with the high risk of recurrence and arrive at more rational decisions for proper treatment. In order to investigate the prognostic significance of bcl-2, an immunohis-tochemical staining was performed in 35 tissue sections from paraffin blocks of primary breast cancer. Bcl-2 positivity was 43%. No relation could be observed between bcl-2 expression and known prognostic factors(tumor size, lymph node metastasis state, histologic grade, and nuclear grade), There was strong relation between bcl-2 expression and estrogen receptor positivity (ER) (P〈0.05). No relation is found between bcl-2 expression and c - erbB - 2 expression. These results suggest that bcl-2 expression is associated with a favorable prognostic factor(ER) but it is of no value as independent prognostic factor to the clinician in identifying the patients with high risk of recurrence.

버스정보시스템(BIS)을 위한 모바일 환경의 시각화 기법 연구

박동규,박진화,이수진,박은호,류동성,어윤 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

In this paper we describe a visualization method for Bus Information System(BIS) on Mobile Environment. A BIS is a key service for Intelligent Transport System(ITS) on public transportation area. We present a client-server based visualization technique for bus route information over Internet Protocol and user-oriented regional information service with a voice and animation. We also describe the design and implementation of this kind of schematic map generation system with icon and label.

반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.