대성리 국민 관광지의 운영 실태와 관리 방안

이대희(Lee Dae-hee) 서울행정학회 2002 한국사회와 행정연구 Vol.12 No.4

The purpose of this study is to examine the facts, problems and to recommend a new strategic direction for the management at Dae-Sung Ri public tourism resort. To perform this research, I discuss the theoretical investigation of public tourism resort. and do statistical analysis. The data was collected from university students and local residents through a questionnaire. The statistical analysis of data was made using the factor analysis and the multiple regression. The results of factor analysis was the followings: 1) the institution kindness intention, 2) the activity intention. 3) the rest intention, 4) the knowledge intention, 5) the price intention, 6) the sensitivity intention. The multiple regression analysis was performed in this study based on the six factors. The end result of the analysis proved that the top three factors that had the most significant impact on tourist's satisfaction are in the following order: 1) the activity intention, 2) the sensitivity intention and 3) the institution kindness intention. This study suggests that, in order to provide high quality service to the tourist and promote the customer satisfaction, the management at Dae-Sung Ri public tourism resort should realign its strategy to put more emphasis and resources on those factors.

참동계고이의 편찬과 구조

이대승(Lee Dae-seung) 한림대학교 태동고전연구소 2013 泰東古典硏究 Vol.30 No.-

본 글은 주희의 참동계고이에 대한 연구이다. 본 글에서는 심도 있는 참 동계고이 연구를 위한 토대작업으로서 참동계고이의 집필시기와 편찬과 정, 참동계고이의 판본, 그리고 그 구조를 다루었다. 주희는 1186년(57세) 즈음부터 참동계에 이미 관심을 갖고 있었다. 그는 채원정과 함께 1196년부터 집필 작업을 시작하여, 1197년 말엽과 1198년 초엽 사이에 채원정의 아들 채연으로 하여금 1차 간행본을 출판케 한다. 그리고 주희는 이후 수정작업을 거쳐 1199년 봄에 정본을 간행한다. 주희 당시 간행된 채연본은 현재 통행되지 않으며, 현행본은 원대 황서절이 편집한 것으로서 경문과 주석의 문자에서 채연본과 약간의 차이가 있는 것으로 보인다. 주희의 참동계고이는 팽효의 참동계분장통진의를 바탕으로 다른 참동계 판본 들과의 비교·대조 작업을 거쳐 저술된 것으로, 그 구조는 다른 참동계 판본과 큰 틀에서 유사하다. This thesis is a foundation research for an in-depth study for Chantong qi kaoyi (參同契考異) of Zhu Xi and aims to examine the publication and structure of Chantong qi kaoyi. Zhu Xi was already interested in Zhouyi cantong qi (周易參同契) by 1186, his 57 years of age. He started to write Chantong qi kaoyi through a cooperation with Cai Yuanding (蔡元定) in 1196 and made Cai Yuan (蔡淵) publish the first version of Chantong qi kaoyi between end of 1197 and beginning of 1198. He published the formal edition of Chantong qi kaoyi in the spring of 1199 through an amending work with Cai Yuan. The edition of Cai Yuan does not pass on these days, and the current edition is the edition of Huang Ruijie (黃瑞節) on Yuan (元) dynasty, which is a little bit different with the edition of Cai Yuan. Chantong qi kaoyi was made by the comparative study with other Zhouyi cantong qi editions on the basis of Cantong qi fenzhang tong zhenyi (參同契分章通眞義) of Peng Xiao (彭曉). The structure of Chantong qi kaoyi is generally similar with the other editions of Zhouyi cantong qi.

Toluene, Xylene, Trichloroethylene 투여가 흰쥐의 시상하부와 뇌하수체의 GnRH, GnRH Receptor, Pit-1 유전자 발현에 미치는 영향

기노석,이종태,강대성,김대환,이채관,이헌,전진호,김정호,이채언 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

The workplace exposure of chemicals has steadily increased, therefore the concern for subsequent effect on reproductive outcome has been an important issue in occupational medicine. In previous studies, higher rates of spontaneous abortion, reduced fertility and menstrual disorder among women, and an impairement of sperm quantity and quality among men have been associated with a wide variety of chemical agents. This study was conducted to evaluate the effects of toluene, xylene and trichloroethylene(TCE) injection on the mRNA levels of GnRH, GnRH receptor and Pit-1 genes in male rats hypothalamus and pituitary and the effects on the plasma levels of FSH, LH, prolactin and testosterone. Sprague-Dawley male rats were divided into five groups of five each according to concentration of toluene, xylene and TCE. The rats were injected subcutaneously to 0, 50, 100, 200, 400 mg/kg body weight/day of toluene, xylene and TCE, respectively for 6 days. Rat brains were excised and hypothalamus and pituitary were separated. Reverse transcription-polymerase chain reaction (RT-PCR) and RNase protection assay(RPA) were used to evaluate the GnRH, GnRH receptor and Pit-1 mRNA levels. Plasma concentrations of FSH, LH, prolactin and testosterone were assayed by radioimmunoassay(RIA). The results were as follows; 1. GnRH, GnRH receptor and Pit-1 mRNA levels in toluene and xylene injected groups, and GnRH receptor mRNA levels in TCE injected group were lowered dose-dependently. Especially, GnRH receptor and Pit-1 mRNA levels in 200mg/kg of toluene injected group, and GnRH, GnRH receptor and Pit-1 mRNA levels in 400mg/kg of toluene injected group were significantly lower than control group (p<0.05). GnRH receptor and Pit-1 mRNA levels in 400mg/kg of xylene injected group, and GnRH receptor mRNA levels in 400mg/kg of TCE injected group were significantly lower than control group(p<0.05). 2. The plasma levels of prolactin and testosterone in 400mg/kg of toluene injected group, and LH in 100, 200 and 400mg/kg of xylene injected group, and testosterone in 400 mg/kg of TCE injected group were significantly lower than control group(p<0.05). In conclusion, we speculated that toluene and xylene affected reproductive system secondarily through hypothalamus-pituitary axis, and TCE affected directly through steroidogenesis. And we recommended that further study for assessment of the reproductive toxicity of mixed organic solvent exposures should be conducted.

교통사고 후 발생한 경항통 환자에 대한 황련해독탕약침과 분리정제봉약침의 치료 효과 비교연구: 무작위 배정

이옥진 ( Yu Chen Lee ),남대진 ( Dae Jin Nam ),허건 ( Gun Huh ),이재은 ( Jae Eun Lee ),김빛나라 ( Bin Na Ra Kim ),송은모 ( Eun Mo Song ),이은정 ( Eun Jung Lee ),이정민 ( Jung Min Lee ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4

ObjectivesThe purpose of this study is to compare the effects of HWANGRY-UNHAEDOKTANG Pharmacopuncture and Essential Bee Venom pharmacopuncture on cervical pain caused by traffic accident.MethodsThe clincal study was conducted to traffic accident patients who had admitted to Dae-Jeon University Cheonan Oriental Hospital from May 17, 2014 to September 2, 2014. The patients were simple randomization and divided into two groups. In one group, patients were treated with the oriental medicine and HWANGRYUNHAEDOKTANGPharmacopuncture, While in the other group, patients were treated with the oriental medi-cine therapy and Essential Bee Venom pharmacopuncture therapy. visual analogue scale (VAS), pain threshold and neck disablity index (NDI) were used To estimate the efficacy of Pharmacopuncture treatment.Results1) HWANGRYUNHAEDOKTANG Pharmacopuncture Group showed significant decrease of VAS and NDI after 3rd times treatment than before treatment (p<0.001). Essential Bee Venom Pharmacopuncture showed significant decrease of VAS, NDI and improve ment of pain threshold after 3rd times treatment than before treatment (p<0.01, p<0.001). 2) There was no significant difference between HWANGRYUNHAEDOKTANGPharmacopuncture group and Essential Bee Venom Pharmacopuncture group in VAS, pain threshold and NDI. ConclusionsWe found out that HWANGRYUNHAEDOKTANG Pharmacopuncture and Essential Bee Venom Pharmacopuncture treatment are considered to be effective and useful in cervical pain caused by traffic accident. (J Korean Med Rehab 2014;24(4): 145-153)

악성 림프종 환자에서 발생한 다형홍반

여운철,조광현,이유신,허대석,이승철 ( Un Cheol Yeo,Kwang Hyun Cho,Yoo Shin Lee,Dae Seog Heo,Seung Chul Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

A Case of Erythema Multiforme A ssociated with Malignant Lymphoma Un Cheol Yeo, M.D., Kwang Hyun Cho, M.D., Yoo Shin Lee, M.D., Dae Seog Heo*, M.D., Seoung Chul Lee**, M.D Department of Dermatology and Internal Medicine*, College of Medicine, Seoul National University, Seoul, Korea, Department of Dermatology**, College of Medicine, Inha University, Kyung Gi Do, Korea We report a case of erythema multiforme associated with malignant lymphoma. Fifty-six-year-old male patient visited our clinic complaining generalized skin lesions which were compatible with erythema multiforme clinically and histopathologically. The skin lesions were treatment-resistant, recurrent and persistent for 3 years. In consideration of old age, atypical features of erythema multiforme and no other demonstrable etiology of erythema multiforme, we studied for internal malignancy. Malignant lymphoma at the duodenum was revealed by UGI series, abdominal CT, and endoscopic biopsy. After chemotherapy, the tumor mass and active skin lesions were cleared simultaneously. Erythema multiforme may be regarded as one of the paraneoplastic syndromes.

cDNA array 방법을 이용한 망간에 노출된 흰쥐 뇌기저핵의 유전자발현 분석

이채관,노성민,문덕환,,김정호,손병철,김대환,이창희,김휘동,김정원,김종은,안진홍,이채언 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Objectives: This study investigated the gene expression profile in basal ganglia of manganese-exposed rats based on cDNA array analysis. Methods: For cDNA array, 25 male Sprague-Dawley rats (250±25 g) were intraperitoneally injected with 25 ㎎/㎏ B. W./day of MnCl2 (0.3 ㎖) for 10 days. For dose-related gene expression analysis, rats were intraperitoneally injected with 0.2, 1.0, and 5.0 ㎎/㎏ B. W/day of MnCl2 for 10 days. Control rats were injected with an equal volume of saline. RNA samples were extracted from brain tissue and reverse-transcribed in the presence of [α^(32)P]-dATP. Membrane sets of the Atlas Rat 1.2 array Ⅱ and Toxicology array 1.2 kit (Clontech, Palo Alto, CA) were hybridized with cDNA probe sets. Northern blot hybridization method was employed to assess the dose-related gene expression. Results: Fifty-two genes showed significant changes in expression of more than two-fold. Twenty-eight were up-regulated and 24 were down-regulated in the manganese-exposed group compared to the control. Among the 52 genes, 28 genes including nuclear factor I-X1 (NF1-X1), neuroligin 2 and 3, mitochondrial stress-70 protein (MTHSP70), neurodegeneration-associated protein 1 (Neurodap 1), multidrug resistance protein (MDR), and endoplasmic reticulum stress protein 72 (ERP72), were reported for the first time related to the manganese-induced neurotoxic-metabolism in the rat basal ganglia. According to the dose-related gene expression analyses, MTHSP70, Neurodap 1 and ERP72 genes were up-regulated compared to the control even in the group exposed to low manganese dose ( 0.2 ㎎/㎏ B.W./day). Conclusions: Twenty-eight genes detected for the first time in this study were closely related to the manganese-induced neurotoxic-metabolism in the rat basal ganglia and further study of these genes can give some more useful information about the manganese metabolism.

국가예방접종전산등록체계 개발을 위한 민간의료 기관 하부구조 및 환경 조사연구

이무식,김은영,이건세,이석구,홍지영,김건엽,김대경,신의철,이연경,기몽서,나백주,김영택 한국모자보건학회 2003 한국모자보건학회지 Vol.7 No.2

The Effect of Position in Utterance on the Duration of Segment in Korean

Lee,Hyun-Bok,Kim,Dae-Won 한국언어학회 1991 언어 Vol.16 No.1

한국과 일본기업의 경쟁우위비교분석

이장호,이남주,이대선 韓國國際經營學會 1993 國際經營硏究 Vol.4 No.1

본 연구는 한국과 일본 기업의 경쟁우위의 원천을 파악하고 이를 상호비교함으로써 우리기업의 경쟁우위개발에 관한 시사점을 도출하고자 한다. 한국과 일본기업간에 경쟁우위상에 차이가 있는지 여부를 알아보기 위하여 실시한 t검증결과 일본기업의 Tobin`s q의 크기는 한국기업의 그것의 약2배에 달한다. 個別變數들을 독립변수로 한 회귀분석의 결과는 한국기업의 경우에는 재무지표를 중시하는 것과 구성원들을 비용으로 취급하지 않고 자산으로 보는 것이 경쟁우위에 정의 영향을 미친다는 것을 시사한다. 일본기업의 경우에는 근로자의 제안을 경영에 잘 반영하며 상표를 중시하는 것이 일본기업의 경쟁우위에 정의 영향을 미친 다는 것을 시사한다. 한편 요인분석결과를 보면 한국과 일본기업은 공통적인 경쟁방법들을 사용하고 있는 것이 사실이지만 일본기업들의 경우에는 환경분석과 부품업체와의 협력이라는 한국기업들이 일견 등한시 하는 경쟁방법도 사용하고 있다. 요인분석에서 추출된 요인들을 독립변수로 사용한 회귀분석은 한국기업의 경우에는 직원들을 자산으로 보는 것이 경쟁우위에 정의 영향을 미치며 일본기업의 경우에는 우리의 예상과는 달리 부품업자들과 협력 하는 것이 경쟁우위에 負의 영향을 미친다는 것을 시사한다. ㅣ

Hong Dae-yong’s Beijing Travels and His Changing Perception of the West-Focusing on Eulbyeong yeonhaengnok and Uisan mundap

Lee Hyung-dae The Academy of Korean Studies 2006 THE REVIEW OF KOREAN STUDIES Vol.9 No.4