국산 머루주의 품질 특성 및 생리기능성

이대형,유형은,이종수 배재대학교 자연과학연구소 2004 自然科學論文集 Vol.15 No.1

To develop a new functional fruit wine, quality characteristics and physiological functionality of wild grape wine(WGW) were investigated and compared with that of foreign grape wine(FGW). Ethanol contents of WGW was 11.0%, similar to that of FGW(10.6%), but total acidity(0.67%) and total anthocyanin content(A_(520): 0.32) of WGW were higher than those of FGW(0.4%, 0.22). Antioxydant activity and SOD-like activity of WGW which is related in anti-aging functionality were 93.6% and 53.0%, respectively, higher than those of FGW(85.9%, 42.5%). From this results, we concluded domestic wild grape wine is very excellent functional fruit wine.

남성·여성의 혼합DNA에서 Y-STR의 유효성 검토

이양한,신상철,이은정,박정우,구형남,김대열,김윤신 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

골형성부전증 10예의 임상적 특징

이형숙,김현주,조재현,이승원,김현아,최준혁,송영준,김대중,이관우,정윤석 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.5

연구배경 및 방법: 골형성부전증은 비교적 희귀한 유전병으로 교원질 대사 장애로 인한 골의 취약성과 다발성 골절 및 척추측만증 등을 특징으로 한다. 유전방식과 표현형의 발현 정도에 따라 다양한 임상 양상을 보이며, 임상적 중증도에 따라 4가지 형태로 분류된다. 지금까지 국내 보고는 분만과정이나 태아 진찰시 골격이상으로 발견된 증례보고가 주였다. 저자들은 비교적 경미한 임상 양상을 보이는 예를 포함한 다수의 골형성부전증 환자들의 전반적인 임상적 특징에 대해 보고하는 바이다. 결과: 2001년 6월부터 2003년 2월까지 골형성부전증으로 진단받은 6 가계, 10예를 대상으로 하였다. 평균 나이는 27.3(5∼56)세였고 소아가 2예였다. 모두 상염색체 우성으로 유전되었으며, 제 I형이 4예, 제 III형이 4예, 그리고 제 IV형이 2예였다. 전 예에서 다수의 골절 경험이 있었고, 골밀도 저하와 골피질 두께 감소 소견이 관찰되었다. 전신의 평균 골밀도는 0.690(0.421∼1.039) g/cm²였다. 골형성지표로 측정된 sAlk는 소아의 경우만 증가되어 있었고, 골흡수지표로 측정된 uDPD의 평균치는 12.9(4.4∼36.3) nM/mM Cr으로 증가된 소견을 보였다. mobility score는 대부분 3,4단계에 속해 있었다. 중증형일수록 진단 시의 mobility score가 낮은 경향을 보였다. 결론: 한국인 골형성부전증 환자의 임상적 특징을 살펴본 결과 기존의 보고된 II형 외에도 I, III, IV형이 다양하게 존재함을 알 수 있었으며, 모든 예에서 상염색체 우성으로 유전됨을 확인할 수 있었다. 또한 모든 예에서 증가된 골흡수로 인한 골밀도 저하와 골절을 확인할 수 있었다. Osteogenesis Imperfecta (OI) is a relatively rare hereditary disease, which is characterized by multiple bone fractures and spine scoliosis, due to the fragility of bone, and is often associated with blue sclerae, deafness and dentinogenesis imperfecta. Four types of OI can be distinguished, according to the clinical findings. Although mutations affecting type I collagen are responsible for the disease in most patients, the mechanism by which the genetic defects cause abnormal bone development remains to be fully understood. Here, the clinical characteristics of 10 OI patient cases are reported, with a review of the literature. All the cases, including 4 type I, 4 type III and 2 type IV, inherited OI as an autosomal dominant trait. All the subjects had multiple old fractures and decreased bone densities. In this study, the biochemical marker of bone formation, serum alkaline phosphatase, was found to be increased only in the pediatric OI patients, while the biochemical marker of bone resorption, urinary deoxypyridinoline, was increased in all cases. The mobility score was found to correlate with the severity of the type on diagnosis (J Kor Soc Endocrinol 18:496∼503, 2003).

NRW-100을 이용한 H-Na, H-Mg, H-Cs, H-Cu 2성분 양이온 교환 특성

이인형,안현경,김상대,윤형준 순천향대학교 부설 산업기술연구소 2004 순천향 산업기술연구소논문집 Vol.10 No.1

Ion exchange if the most reliable process for removing ionic impurities and is the economic operation with reuse of the resin. Ion exchange is widely used in water and wastewater treatment, especially softening and demineralization. Ion selectivity depends on the hydrated radius, charge of ions and ionic concentration. The objective of this study is to determine the selectivity order of cations with equilibrium and column ion exchanges, and to investigate the effect of the background anion on selectivity. Cation selectivity increases with decreasing concentration and increasing charge(H^+<Na^+<Cs^+<Mg^2+<Cu^2+) in equilibrium and column cation adsorptions.

후이개에 발생한 거대 표피양낭종 1예

강태형,이환호 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Epidermoid cyst is slowly growing, round and firm tumor. Generally it grows up to 0.5 to 5 cm in diameter. Epidermoid cyst is rarely found in postauricular region. The cyst is intradermal or subcutaneous sac-like structure that is surrounded by keratinized epithelium with no dermal annexe in its covering epithelium. In surgical treatment, the cyst wall must be completely removed because residual portions of it can result in cyst recurrence. We report a case in which a 41-year-old man developed an epidermoid cyst presenting as a large postauricular swelling with a review of literature.

농부가 아닌 환자에서 발생한 긴털가루진드기(Tyrophagus Putrescentiae)에 의한 기관지천식 1례

최대로,김형수,고창옥,김희선,윤호성,박용범,김상훈,이재영 대한천식 및 알레르기학회 2004 천식 및 알레르기 Vol.24 No.1

Storage mites are believed one of the most important allergens in farmers and rural regions. Tyrophagus putrescenitiae, belonging to storage mites, is found not only within storehouses but also in the house dust, and the third most common mites following Dematophagoides farinae and Dermatophagoides pteronyssnus in house dust in Korea. The sensitization rate to Trophagus putrescentiae was reported as high as that of house dust mite in patients visiting the allergy clinic in large cities in Korea. We experienced a 69-year-old man who had suffered from dyspnea, wheezing, and coughing for 10 years. He retired from the teaching profession, and had lived in a large city. Deajeon. The skin prick test showed a positive reaction to Tyrophagus putrescentiae and negative reactions to house dust mites. The bronchial challenge test with Tyrophagus putrescentiae showed late asthmatic reaction. We confirmed a Tyrophagus putrescentiae induced asthma in non occupational setting. (J Asthma Allergy Clin Immunol 24 : 141-5, 2004)

대기오염과 천식증상에 의한 응급실내원과의 연관성에 관한 환자교차연구

임형준,이상윤,윤기정,주영수,강대희,조수현 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : This study, using case-crossover design, search a relationship between changing levels of air pollutants and asthma attack in asthma patients. Methods : We searched the daily total number of asthmatic patients at hospital's emergency room in Seoul, Korea by investigating total 49 general hospital's emergency room records. Otherwise, We investigated medical records of asthmatic patients at one of the 49 hospitals we have searched. We investigated addresses that they are living, diagnosis, smoking history, whether respiratory infection or not, medications. We analyzed the data by 1:m conditional logistic regression used when matched case-control study is analyzed. Control periods were chosen by bidirectional paired matching technique 7, 14 days before and after case periods. Results : the relative risk of asthmatic attack by 100 ppm ozone increase between June and September were 1.348(95 % CI = 1.010∼1.619). Between November and February, the relative risk by 100 ㎍/㎥ TSP increase, 100ppb sulfur dioxide and nitrogen dioxide were respectively 1,278(1.010∼1.619), 1.237(1.019∼1.502), 1.285(1.006∼1.640). In stratified analysis, the relative risk were significant when the asthmatic patients were children aged 15 years or below, when there were respiratory infection, and when the patients took medications irregularly Conclusions : There was statistically significant association between ambient levels of air pollutants and asthmatic attack. So, we have to exert our efforts to minimize the air pollution effectively, to protect public health from air pollution.

전단보강된 RC보의 거동에 관한 실험적 연구

정영수,이대형,손창호 中央大學校 建設環境硏究所 1995 環境科學硏究 Vol.6 No.-

Since the mid of 1970's Korea, the construction of infrastructures has been booming and accelerating to keep up with rapid economic growth. Fast achievement of most construction activities has caused unfavorable effects of civil petitions associated with damages and nuisances due to last hasty works. Recently, unexpected collapses of Sungsoo grand bridge, Sampoong department and other reinforced concrete structures have been continually occurred because of the construction not conforming with the specification, and thereby incurred enormous loss of life and property. Thus, a periodic inspection and maintenance have been strongly interested on aged RC structures, of which lifetime becomes over 20 years. Because of insufficient data about repair and rehabilitation technique in the country, most repairing and reinforcing works have been unsystematically performed under the guidance of few local companys more or less experienced in this field.

BOM에서의 조립 순서 생성을 고려한 확장성에 관한 연구

장현수,김대형,이병기 明知大學校 産業技術硏究所 2000 産業技術硏究所論文集 Vol.19 No.-

BOM has been widely used to manufacturing, product design and scheduling. There are several bug differences between Manufacturing BOM and Engineering BOM, which cause a lot of problems. A study to integrate both manufacturing BOM and Engineering BOM is researching to solve those problems. This thesis presents a extended Engineering BOM concepts considering assembly sequence model.

형광검출 역상 액체크로마토그래피에 의한 Histamine의 정량

유희춘,김형룡,김상현,김대기,이영미,김형민,안년형,신태용 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

Histamine을 정확하고 신속하게 정량하기 위해 9.Fiuorenylmethyl chloroformate를 형광유도체화제로 하여 역상 HPLC법으로 정량하였다. 히스타민을 형광유도체화할 때 반응액의 pH, 반응시간, 형광유도체화제의 농도 등 최적 반응 조건을 검토하였다. 이 방법으로 히스타민을 분석한 결과 0.1~0.5ug/ml의 농도범위에서 상관계수가 0.922인 양호한 직선성을 나타내었으며 검출한계는 0.01??/ml였다. A rapid and simple method for the determination of histamine by reverse-phase high performance liquid chromatography with fluorescence detection was established. 9-Fluorenylmethyl chloroformate(FMOC) was used as fluorescent derivative reagent. The optimum conditions for the derivatiation such as pH, reaction time and he concentration of FMOC were investigated. Linearity of calibration curve was obtained between 0.1ug/ml/and 0.5ug/ml(r=0.922) and the limit of detection was 0.01ug/ml.