시각의 노화를 고려한 노인종합복지관의 색체계획에 관한 연구

정준수,임환준,이현희,박용환 대한건축학회 2003 대한건축학회논문집 Vol.19 No.7

As human become aged, he become color weak due to yellowed eye sight. The 87% of information for human behavioral decisions are visually perceived. Therefore, the color weakness will affect his behaviors in many ways. Most of previous research regarding color planning for the aged people focuses on discovering their preferred colors and reflecting the colors on facility color planning. But these research failed to identify confused range of color cognitions due to the color weakness of the aged. In this research, targeting the aged in multi-purpose senior centers, we analyze their color distinctions and confusions using computer graphic tools. Our research discovers several important points. First, there are differences in color cognitions between the young facility designers/staffs and the aged facility residents. Second, these differences lead to the differences in the abilities of spatial cognitions between the young and the aged. Third, the difference in the spatial distinctions if mainly caused not by color itself but by color adjacencies. Based upon these findings, we propose that color planning of facilities for the aged be made not from the view of the designers but from the view of the aged, considering yellowed eye sight of the aged.

非線形 肺 가스 結合特性의 電氣的 모델化

鄭亨煥,周秀元,李浚柝 동아대학교 공과대학 부설 한국자원개발연구소 1987 硏究報告 Vol.11 No.1

A newly derived O₂ Saturation Model which can adapted to the design and study of Artificial Lung and Blood Gas Calculator etc. is introduced on the of Electrical Equivalent Circuits. The presented 4 stage and 2 stage RC circuits have good correlations with actual chemical reactions of Hemoglobin and Oxygen. However from the results of computer simulations, 2 stage equivalent model is more accurate than 4 stage and conventional O₂ saturation models.

담낭 방선균증 1예

김형수,정진원,김양수,우준희,송현순,류지소,김명환,김남중 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

저자들은 우상복부 통증과 소화불량을 주소로 내원한 83세 여자 환자에서 국내 최초로 담낭 방선균증을 진단하고 치료 관찰 중으로 이에 문헌고찰과 함께 보고하는 바이다. Actinomycosis is a chronic suppurative and granulomatous disease, characterized by abscess formation, tissue fibrosis, and draining sinuses. Actinomycosis of the gallbladder is very rare and has not yet been reported in Korea. We report a case of actinomycosis of the gallbladder in an 80-year-old women with history of cholelithiasis for 3 years, preoperatively misidentified as gallbladder cancer. Histologic section of the gallbladder showed Gram-positive branching bacilli compatible with actinomyces. After cholecystectomy, the patient received intravenous ampicillin for 4 days, followed by amoxicillin for 4 months thereafter.

요추 추간판 탈출증의 수술 요법과 효소 요법과의 비교 연구

오석전,김광명,김남규,정환영,이경석 한양대학교 의과대학 1987 한양의대 학술지 Vol.7 No.2

A comparative study was presented on three different therapeutic methods for herniated lumbar discs, i.e., standard discectomy, microsurgical discectomy and chemonucleolysis. For seven year period from 1980 to 1987. 3000 patients with herniated lumbar disc were selected for comparison. Each thousand patients received one of the above three methods. Not only the overall success rate but also various clinical characteristics were compared and analysed with chi-square tests. Microsurgical discectomy ccording to Chung's modified method brought the best results in not only success rate but also in failure and complication rates. The efficacy of chemonucleolysis was relatively low in this comparision, but in selected cases, it was as effctive as microspurgical discectomy. Along with its strong advantages in hospital stay, time to return to work and operating time, chemonucleolysis was the least invasive one. Thus chemonucleolysis could be perfomed with better expected success rate and the following situations. 1) The age of patient was less than 50, 2) radiating pain was a dominant symptom, 3) the symptom lasted shorter than 1 year, 4) lesions were not in L5-S1 level, 5) the patient had more than 3 abnormal findings in 5 physical and neurological signs, i.e., motor weakness, detmatomal sensory loss, reflex change, positive straight leg raising test and crossed straight leg raising test, and 6) no severe compression in myelogams. In the other two situations, chemonucleolysis could be indicated as an initial treatment. There are 7) patients of over 70-year-old and 8) lesions in more than 3 levels. No serious complications were not found in chemonucleolysis. Meanwhile in the following cases, microsugical discectomy should be considered as the first therapeutic method. 1) patient in the 6th and 7th decades, 2) low back pain as a dominant symptom, 3) duration of symptoms more than 1 year, 4) lesions in L5-S1, 5) only 2 abnormal findings in 5 signs decribed above, and 6) severe compression in myelograms. Standard discectomy did not show any significant advantages over the two methods in this comparative analysis. Any single therapeutic method could not be the best way in the treatment of patients with the herniated lumbar disc. It is desirable to choose the most suitable method for each patient according to not only the success rate of an individual method but also his clinical characteristics, radiological features, surgeon's experience and preference, and the choice of the patient himself.

국내 주방쓰레기 발생실태에 관한 연구

민달기,박준환,정연규,정연균 연세대학교 산업기술연구소 1993 논문집 Vol.25 No.1

The waste generation rate of Korea is the first rank of the world and waste generation rate is 2.3 kg per capita per day. In spite of the severe waste problem, the management of wastes is very weak and most of wastes landfilled simply, and the study of waste generation and characteristics is also poor. Therfore, in this wtudy, waste source, unit discharge rate and physicochemical property of organic fraction of muicipal solid wastes, (especially food wastes, are inverstigated, and future waste generation is predicted using DYNAMO simulation. As the result, generation rate of food wastes in dwelling area, market place, cafeteria, and food feeding center are 187 g/cap/day, 975 g/㎡/day, 427 g/㎡/day, and 191 g/cap/day respectively. In addition, the total amount of food wastes generation in Korea is estimated 16,395ton/day (or 6million ton/year), or 454g/cap/day as a unit discharge. Also, the food wastes fraction of the total wastes in the year of 2000 and 2010 is predicted increasing by 31.4%(19,302ton/day) and 35.3% (24,362ton/day)respectively.

형질전환 제초제저항성 벼 밀양 204호의 농업적 특성

정응기,이기환,원용재,박향미,전남수,최준호,구연충,한창덕,은무영,김태산,남민희 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

This study was conducted to investigated the major characteristics of genetically modified rice of "Milyang 204" originated from Dongjinbyeo compared to a non-transgenic rice varieties Dongjinbyeo and Junambyeo. Basta resistant transgenic rice lines carrying bar gene produced by the Yeongnam Agricultural Research Institute were evaluated for their agronomic characters. The transgenic Japonica rice of "Milyang 204" showed inferior phenotypic traits compared to a non-transgenic rice variety Dongjinbyeo and Junambyeo. On the basis of UPOV (Union Internationale Pour la Protaection des Obtentions Vegetables) and NSMO(National Seed Management Office) the transgenic "Milyang 204" showed difference in some traits out of some agronomic traits, such as leaf color, angle of flag leaf, number of spikelets, culm length, white core and white belly compared to the nontransgenic varieties rice.

Methotrexate 치료를 받고 있는 활동성 류마티스 관절염 환자에서 etanercept의 유효성과 안전성에 관한 연구

최병렬,강태영,정청일,이혜순,엄완식,김태환,전재범,유대현,배상철 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 류마티스 관절염을 앓고 있는 한국인 중에 기존 DMARDs로 치료 실패하였고, 고정용량의 MTX를 복용하고 있는 환자들에 있어서 etanercept의 유효성과 안전성을 평가하고자 하였다. 방법 : 기존 DMARDs로 치료 실패한 활동성 류마티스 관절염 환자 76명을 대상으로 하여 단일군, 공개시험을 하였다. 대상 환자들은 고정용량의 MTX를 복용하면서 etanercept 25 mg을 1주일에 두 번 피하 주사하였으며 12주간 투여하였다. 유효성은 ACR 20, ACR 50,조조강직 시간으로 평가하였고, 약제의 안전성은 이상반응 등으로 평가하였다. 결과 : 대상 환자는 총 76명으로 평균 연령은 45.2세, 남자 5명, 여자 71명이었다. 84.4%인 54명이 12주째에 ACR 20을 만족하였고, 53.1%인 34명이 12주째에 ACR 50을 만족하였다. 조조 강직 시간은 치료 전 203.3분에서 치료 12주째 42.6분을 평균 74.5% 호전되었다. 가장 흔한 이상반응은 주사부위 반응이었다. 이외에도 상기도 감염, 오심, 안면부종 등이 발생하였으나 심각한 부작용은 없었다. 결론 : etanercept는 효과적이고, 안전한 류마티스 관절염 치료 방법이며 특히 MTX치료에도 불구하고 활동성인 류마티스 관절염에 기대되는 치료라고 할 수 있다. Background : This study was performed to investigate the efficacy and safety of etanercept in active rheumatoid arthritis patients with stable dose of methotrexate in Korean. Methods : In a 12 week, single arm, open trial, we assigned 76 patients with active rheumatoid arthritis who had an inadequate response to disease-modifying antirheumatic drugs. Patients received twice-weekly subcutaneous injections of etanercept 25 ㎎ while containing to receive methotrexate at a stable dose of 7.5~25 ㎎ per week. The clinical response was defined as the percent improvement in disease activity according to the criteria of the American Collage of Rheumatology (ACR) at 12 weeks. Results : Etanrecept led to significant improvements in disease activity and was safe and well tolerated. At 12 week, 84.4% of the patients receiving 25 ㎎ of etanercept achieved a 20% ACR response, and 53.1% of those receiving etanercept achieved a 50% ACR response. The most common adverse event was injection-site reaction. Other advanse events were upper respiratory infection, nausea, and facial edema, but there were no serious adverse events associated with etanercept. Conclusion : In active rheumatoid arthritis patients, etanercept was safe, well tolerated, and provided rapid clinical improvements.

하악골 절제술후 재이식된 돌결자가골 재이식 : 치험 3례

김 식,김수관,김운규,김수민,류종희,이준길,조경안,김수흥,정태영,여환호 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

We described three cases of immediate reimplantation of a frozen-thawed autogenous mandible composed of a mixture of iliac bone, marrow, and particulate hydroxyapatite in tumors of the mandible. Acceptable outcomes were obtained in three patients who underwent immediate autogenous mandibular graft reconstruction. The conditions leading to successful outcome of the procedure are also discussed. Reimplantation of frozen autogenous lesioned mandible was performed in three patients with mandibular tumors. Two reimplanted grafts survived without complications following surgery. One case had postoperative infection that resolved with appropriate antibiotic treatment. There were no recurrences of the primary lesions. Satisfactory facial contour after surgery was achieved. These results are most promising, and we believe that, with further refinement, this technique will offer a new and acceptable modality for facial reconstruction in patients with cancer.

구급일지를 통한 병원 전 환잔 분류 및 처치의 적절성 평가 연구

민순식,김재광,이근,박철완,양혁준,류일,현성열,이훈규,정환모,김윤 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: Recently, patients' demands for emergency medicine are increasing, and most of prehospital medical care, including basic life support, cardiopulmonary resuscitation and triage, are provided by paramedics or emergency medical technicians. Evaluation of the adequacy of prehospital management and triage has become important for improving the quality and the effectiveness of the emergency medical system. Methods: The 202 patients who were transferred by ambulance with paramedics, nurses, or emergency medical technicians to the Emergency Department in Gil Medical Center from July 1, 1999, to September 31, 1999, were enrolled. This study was conducted prospectively by using the emergency physician,s log and newly devised protocols recorded by paramedics or nurses. Results: 1) Male to female ratio was 1: 0.8, and the peak age of the patients were the 4th(18.8%) and 6th decade(15.3%). 2) Of the 202 patients, 84 patients were transferred for trauma and 118 for medical problems. The mean transfer time was 6±1.73 minutes. 3) The validities of prehospital triage and decisions using the trauma severity measure and the disease severity measure, were 33.3% in trauma patients and 57.6% in medical patients.4) The results for the adequacy rate in prehospital management analyzed by using the rate of necessity of treatment. performance of treatment, and adequate treatment were as follows: oxygen supply.38.1/41.6/93.8 ; wound dressing. 19.3/71.8/92.9 ; immobilization of the cervical spine, 15.8/56.3/92.9 ; application of a spinal board. 12.9/42.3/72.7 ; application of a splint, 9.9/50.0/60.0 ; manual maintenance of an airway. 9.9/55.0/63.6 ; and CPR, 4.5/66.7/0. 5) Kind of ALS(Advanced Life Support) were not conducted(peripheral IV, EKG. intubation, medical administration. defibrillation, pacing). The rates of necessity of treatment were as follows: peripheral IV, 40.6%; ECG monitoring, 23.3% ; endotracheal intubation, 8.9% ; medical administration, 8.9% ; defibrillation. 3.5%; and pacing. 1.5% Conclusion: The adequacy of prehospital triage and decisions using trauma and disease severity measures was relatively low. To improve the adequacy of BLS(Basic Life Support) and to increase the performance of ALS(Advanced Life Support), we must create challenges to develop new protocols and to supplement new equipment.

만성 활동성 간염에 있어서 Ursodeoxycholic acid의 치료효과

김성록,안병철,윤영미,탁원영,곽규식,최용환,정준모 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.4

The purpose of this study is to evaluate the clinical and biochemical effects of SGD-F^(R)(UDCA, Vitamin B_1, Vitamin B_2 complex) in chronic active hepatitis. Observed cases were given orally after each meal(three times a day) for 4 weeks. The results were as follows: 1. Among subjective symptoms, improvement rate showed in easy fatigability 86.7%, anorexia 68.0%, indigestion 80.0%, nausea and vomiting 72.7%, RUQ pain 83.3%. 2. Biochemical parameters such as SGOT, SGPT, showed to be improved significantly after the 4 weeks treatment.(p<0.01) 3. There was no specific side effect during the study period in all cases. In conclusion, SGD-F^(R) capsule may be safe and effective for chronic active hepatitis.