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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
( Han Wook Chung ),( Yu Jin Ko ),( Sang Wook Lee ),( Hyun Woong Lee ),( Hyung Joon Kim ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background/Aims: Quantitative HBsAg (qHBsAg) titers are emerging as useful tools for measuring viral load and predicting predicting virologic response (VR). This study aimed to determine whether serial monitoring of HBsAg levels could predict virologic response to entecavir(ETV) & clevudine(CLV) therapy in treatment-naive patients with CHB Methods: A total of 157 treatment-naive patients with CHB, who visited Chung-Ang University Hospital between January 2007 and December 2008, were enrolled in this study (100 males). 97 patients(69 males, mean age 48) were treated with ETV for average 53 months, and 60 patients (31 males, mean age 43) were treated with CLV for 26months average. HBsAg levels were measured at baseline, week 12, 24, and 48. All patients were assessed for virological response (HBV DNA<140 copies/mL). Serum HBV DNA was quantified using the real time PCR assay (Artus HBV LC PCR Kit, Roche Diagnostics, lower limit of quantification, 140 copies/mL). Results: In 97 ETV-treated patients, the rates of virological response were 56.7% (55/97) at 48months and 60 CLV-treated patients, 30% (18/60) at 24 months, respectively. Mean reduction of baseline HBV DNA was -5.3, and -4.9 log10 copies/mL. In 55 VR patients treated with ETV, 43(78.1%) patients showed early decline of HBsAg titer and 31(56.3%) patients had lower baseline HBsAg levels (< 3.7 log IU/mL). In 18 VR patients treated with CLV, 9(50%) patients showed early decline of HBsAg titer and 11(61.1%) patients had also lower baseline HBsAg levels (< 3.7 log IU/mL) . Conclusions: Early decline of HBsAg was useful for predicting VR, and baseline HBsAg could be indicative as well in CHB patients treated with ETV than patients treated with CLV.
최영식,이상용,김유훈,조갑래,이봉우,양경무,정낙은,서중석,이한영,이원태,강현욱 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2
Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.
三槽式便所를 設置한 濟州道內 一部落民의 寄生蟲感染率 推移
蘇鎭琸,李根泰,鄭坪林,李在興,李定熙,金英漢,洪淳億 최신의학사 1968 最新醫學 Vol.11 No.8
Three compartment stool tank system was established in March, 1965 to each of the houses . of Yongheungri, Cheju-do. The trend of parasites prevalence, faithfulness of the people to paractice the system and effectiveness of the system for destruction of ascaris eggs were examined. 1. Only 22 houses among 65 utilized the system for 3 years. The remained 43, gave up to practice; 10 because of the destruction of the cemented tank and 33 due to the shortage of. food stuffs, for hogs. In this island, the people have been raised hogs with human excrets. 2. The prevalence of ascaris infection in the village and in Sinwom-ri, a control village where the human feces were used as food stuffs for hog, were as follows: Yongheung(%) Sinwom(%) March 1965 before medication 52.0 43.0 Dec. 1965 after medication 15.1 21.2 Feb. 1968 22.7 30.8 3. Ascaris eggs in the 3rd compartment, were destroyed 94-100%, whereas the eggs in semi-formed feces in hog sty survived 94%.
이제현,이한구,김진숙,김연태,김정숙 대한본초학회 1997 大韓本草學會誌 Vol.12 No.2
Hematopoietic actions induced by administration of Astragali radix, Angelicae gigantis radix, Rehmanniae radix preparat and Cervi pantotrichum cornu were compared in SAM R1 and P6. We measured complete blood cells such as RBC, Hb and Hct using Coulter's method and compared the results each other in a view of traditional Korean medicine. The administration of Angelicae gigantis radix did not induce hernatopoietic actions in SAMs and also was quite different those from the other 3 herbs. Thus, the mechanisms of the hematopoietic action by Astragali radix, Angelicae gigantis radix, Rehmanniae radix preparat and Cervi pantotrichum cornu could be different each other.
D-penicillamine 경구투여량 및 투여방법이 요중 연배설에 미치는 영향
이승한,박정일 가톨릭대학 산업의학센타 산업의학연구소 1981 韓國의 産業醫學 Vol.20 No.3
2,3-Dimercapto-1-propanol (BAL), edathamil calcium disodium (Ca-EDTA) and d-peniciiamine (D-PCA) are three typical chelating agents in the treatment of lead poisoning . Of these, D-PCA is relatively non-toxic and it's oral efficacy provides a definite advantage, particularly for the long periods of "be-leading" that are often required in lead poisoning. In order to observe the effect of various dosage schedule of oral D-PCA on urinary lead excretion (ULE), 200~1200mg of oral D-PCA were administered on 90 lead patients for 5 days according to the dosage schedule and 24-hour ULE before and during D-PCA administration were measured by dithizon method. The results were as follows; 1. Five-day average daily ULE increased by approximately 2 to 5 times after daily oral D-PCA of 200~1200mg as compared with initial excretion. Even with 200mg per day, significant increase of ULE was noted. 2. With the same daily dose, ULE was observed, as the higher single dose was given less often. 3. Of all 9 groups, 400mg b.i.d. and t.i.d. groups showed on largest ULE, reaching 4~5 times as compared with initial excretion. 4. Increment of ULE was largest on the lst day, decreased gradually as D-PCA administration proceeded, and showed the significant fall on 5th day.
이철재,정한식,김시범,권순석 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2
The effect of aspect ratio on mixed convection heat transfer in a rectangular enclosure has been studied numerically by the finite difference method. This study has been conducted to evaluate the effects of aspect ratio and position of outlet in the mixed convection for various Reynolds numbers at Pr=0.71 and Gr=10000. Independent of outlet position, as Reynolds number increases, the cell decreases at Re≤100 and then increases at Re〉100 in case R=10., but the cell only increases in case of R+0.5 and R=2.0.
李駿商,鄭然郁,林漢鍾,朴永模 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.3
Paragonimiasis is a common trematodiasis of medical importance and one of public health problems in many areas of southern part of Korea. During the last sixty years, several surveys on the prevalence among the Korean population have been carried out by various investigators, although the general distribution and prevalence of paragonimiasis are not yet clearly determined. This study was undertaken to compare the status of human paragonimiasis in Kwang-Tan Myun, Pa Joo Gun by the use of intradermal screening test with Veronal buffered saline antigen. 1. In 1969, 27.9 per cent of the inhabitant examiners showed positive reaction, with sexual difference of 38.7 per cent in male and 8.3 per cent in female. 2. In 1977, 19.8 per cent of the inhabitant examiners showed positive reaction, with sexual difference of 31.9 per cent in male and 3.8 per cent in female. 3. In 1977, 1.9 per cent of the student examiners showed positive reaction. 4. In the inhabitant examiners, relarively higher positive rate was shown from the age group of 10 years in 1969, but it was shown from the age group of 40 years in 1977.