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      • KCI등재

        Dielectric properties of Mg0.95Ni0.05TiO3 ceramic modified by Nd0.5Na0.5TiO3 at microwave frequencies

        Chun-Hsu Shen,Cheng-Liang Huang,Chuan-Feng Shih,Chih-Ming Huang 한국물리학회 2009 Current Applied Physics Vol.9 No.5

        The effect of Nd0.5Na0.5TiO3 addition on the microwave dielectric properties of Mg0.95Ni0.05TiO3 ceramics was investigated. The Nd0.5Na0.5TiO3 content plays a significant role in improving the dielectric properties. Microwave dielectric measurements show an increase in the dielectric constant (εr) and temperature coefficient of the resonant frequency (τf) and a decrease in the quality factor (Q × f value) with increasing Nd0.5Na0.5TiO3 content. By properly adjusting the Nd0.5Na0.5TiO3 content, a zero τf value can also be obtained, which make Mg0.95Ni0.05TiO3 a promising material in wireless systems. At 1300 ℃, the 0.81Mg0.95Ni0.05TiO3–0.19Nd0.5Na0.5TiO3 ceramics possess excellent microwave dielectric properties: a dielectric constant (εr) of 25.61, a Q × f value of 69,100 GHz, and a τf value of -6 ppm/℃. The effect of Nd0.5Na0.5TiO3 addition on the microwave dielectric properties of Mg0.95Ni0.05TiO3 ceramics was investigated. The Nd0.5Na0.5TiO3 content plays a significant role in improving the dielectric properties. Microwave dielectric measurements show an increase in the dielectric constant (εr) and temperature coefficient of the resonant frequency (τf) and a decrease in the quality factor (Q × f value) with increasing Nd0.5Na0.5TiO3 content. By properly adjusting the Nd0.5Na0.5TiO3 content, a zero τf value can also be obtained, which make Mg0.95Ni0.05TiO3 a promising material in wireless systems. At 1300 ℃, the 0.81Mg0.95Ni0.05TiO3–0.19Nd0.5Na0.5TiO3 ceramics possess excellent microwave dielectric properties: a dielectric constant (εr) of 25.61, a Q × f value of 69,100 GHz, and a τf value of -6 ppm/℃.

      • Risk and Outcome of Stroke in Patients with Liver Cirrhosis: Two Nationwide Studies

        ( Yi-chun Chou ),( Chien-chang Liao ),( Chun-chuan Shih ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

        Aims: The association between liver cirrhosis (LC) and stroke was not completely understood. The purpose of this study is to evaluate stroke risk and post-stroke outcomes in patients with LC. Methods: Using the Taiwan National Health Insurance Research Database, we identified 6944 adults aged ≥20 years diagnosed with LC in 2000-2005. Non-LC cohort consisted of 27776 adults randomly selected and matched by age and sex (case-control ratio=1:4). Incident events of stroke occurring after LC from January 1, 2000, through the end of 2009 were identified in the follow-up period. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of stroke associated with LC were calculated. We conducted another nested cohort study consisted of 21267 patients with hospitalization due to stroke between January 1, 2004, and December 31, 2010. We calculated the adjusted odds ratios (ORs) and 95% CIs of 30-day mortality after stroke in patients with and without LC during admission. Results: The incidences of stroke for people with and without LC were 7.5 and 4.9 per1000 person-years, respectively (P<0.0001). Compared to people without LC, patients with LC had increased risk of stroke (HR 1.75, 95% CI 1.52-2.01). The association was significant in both sexes. In the nested cohort study, LC was associated with post-hemorrhage mortality (OR 1.83, 95% CI 1.63-2.05) and epilepsy (OR 1.30, 95% CI 1.09-1.56). Conclusions: Patients with LC showed higher risks of stroke and post-stroke mortality. Our findings suggest the urgency of preventing and managing LC by a multidisciplinary medical team for this specific population.

      • KCI등재

        A comparative study of the traditional medicine systems of South Korea and Taiwan: Focus on administration, education and license

        김동수,Chun-Chuan Shih,Hung-Chiang Cheng,Soo-Hyun Kwon,Hyun-Min Kim,임병묵 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.3

        Background: Traditional medicine (TM) is widely used in South Korea and Taiwan, and both societies have similar systems for the management of TM. This study aimed to compare the TM systems in South Korea and Taiwan. Methods: We searched for studies on the TM systems and collected statistical data from the websites of relevant government agencies in both countries. Interviews were conducted with experts on TM and officials from government agencies. The two TM systems were described and examined in terms of policies, resources, utilization, licensing, and educational systems. Results: Both South Korea and Taiwan have a dual system that separates the administration, licensing and educational systems between TM and Western Medicine (WM), and the TM systems are well established and highly standardized. Comparing with South Korea, however, Taiwan has a more flexible dual medical system in which education courses for producing dual licensure are provided. Additionally, in the system in Taiwan, dual license holders can use both TM and WM methods without limitations and WM doctors can apply acupuncture under some circumstances. Because of the strict dual medical system in South Korea, TM and WM conflict with each other on most health issues. Conclusion: Both South Korea and Taiwan have the advantages of preserving TM, as TM and WM are systemically independent and together provide a more holistic approach. The institutionalization of TM in South Korea and Taiwan may be a good reference for countries considering modernization of their TM.

      • Poster Session : PS 0318 ; Hematology : Increased Mortality after Stroke in Patients with Immune Thrombocytopenia: A Nationwide Population- Based Study

        ( Chien Chang Liao ),( Ta Liang Chen ),( Chun Chuan Shih ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Limited information was available on the outcomes after stroke in patients with immune thrombocytopenia (ITP). This study evaluated the adverse events after stroke in patients with ITP. Methods: From the claims data of National Health Insurance Database, we conducted a nationwide retrospective cohort study consisted of 2183 stroke patients with ITP between 2002 and 2009. Using matching procedure by propensity score with age, sex, low income, urbanization, teaching hospital, diabetes, hypertension, hyperlipidemia, myocardial infarction, mental disorders, liver cirrhosis, dementia, renal dialysis, anticoagulants, anti-platelet agents, lipid-lowering agents, and types of stroke, we selected 21830 non-ITP patients with stroke during the index date for comparison. Results: After adjustment for sociodemographics, coexisting medical conditions, medications, and types of stroke in the multivariate logistic regressions, patients with ITP had higher 30-day mortality after stroke compared with stroke patients without ITP (odds ratio=1. 41, 95% confi dence interval=1. 15-1. 74). ITP was also associated withincreased medical expenditure after stroke (odds ratio=1. 13, 95% confi dence interval= 1. 01-1. 27). Conclusions: Our nationwide retrospective cohort study investigated the increased risk of mortality after stroke in patients with ITP.

      • KCI등재

        Risk of Diabetic Retinopathy between Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists

        Tzu-Yi Lin,Eugene Yu-Chuan Kang,Shih-Chieh Shao,Edward Chia-Cheng Lai,Sunir J. Garg,Kuan-Jen Chen,Je-Ho Kang,Wei-Chi Wu,Chi-Chun Lai,Yih-Shiou Hwang 대한당뇨병학회 2023 Diabetes and Metabolism Journal Vol.47 No.3

        Background: To compare risk of diabetic retinopathy (DR) between patients taking sodium-glucose cotransporter-2 inhibitors (SGLT2is) and those taking glucagon-like peptide-1 receptor agonists (GLP1-RAs) in routine care.Methods: This retrospective cohort study emulating a target trial included patient data from the multi-institutional Chang Gung Research Database in Taiwan. Totally, 33,021 patients with type 2 diabetes mellitus using SGLT2is and GLP1-RAs between 2016 and 2019 were identified. 3,249 patients were excluded due to missing demographics, age <40 years, prior use of any study drug, a diagnosis of retinal disorders, a history of receiving vitreoretinal procedure, no baseline glycosylated hemoglobin, or no follow-up data. Baseline characteristics were balanced using inverse probability of treatment weighting with propensity scores. DR diagnoses and vitreoretinal interventions served as the primary outcomes. Occurrence of proliferative DR and DR receiving vitreoretinal interventions were regarded as vision-threatening DR.Results: There were 21,491 SGLT2i and 1,887 GLP1-RA users included for the analysis. Patients receiving SGLT2is and GLP-1 RAs exhibited comparable rate of any DR (subdistribution hazard ratio [SHR], 0.90; 95% confidence interval [CI], 0.79 to 1.03), whereas the rate of proliferative DR (SHR, 0.53; 95% CI, 0.42 to 0.68) was significantly lower in the SGLT2i group. Also, SGLT2i users showed significantly reduced risk of composite surgical outcome (SHR, 0.58; 95% CI, 0.48 to 0.70).Conclusion: Compared to those taking GLP1-RAs, patients receiving SGLT2is had a lower risk of proliferative DR and vitreoretinal interventions, although the rate of any DR was comparable between the SGLT2i and GLP1-RA groups. Thus, SGLT2is may be associated with a lower risk of vision-threatening DR but not DR development.

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