좌심방 석회화와 관련된 반복된 좌심방 혈전 1예

김성훈,우성용,오유경,정우백,임철현,신재원,박철수,윤호중,정욱성,홍순조 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.3

韓國農村 새마을 運動의 社會學的 評價

鄭喆洙,朴宗祐 慶北大學校 東洋文化硏究所 1975 東洋文化硏究 Vol.2 No.-

The New Village Movement in Korea was initiated in 1970 to bring about the modernization of Korean rural society through innovations of various kinds. The movement, that is social change, is not an immanent change arising from the social system itself but a contact change from the outside of the system. Nor is it a selective contact change but a direct contact change or a planned change by the government. More than five years have passed since its initiation. Therefore, this paper aims at present to evaluate the present status of the New Village Movement and to measure cultural, technological, and environmental changes, if any, of rural society. Consequently, the study is concerned with the sociological and social psychological examination of the present status of adoption of the innovations within the community. The methods utilized for aquiring data are: formal or informal interviews with the persons concerned, examination of the existing records and the previous studies available, and finally a survey of 439 households. The survey was conducted in February 1975. The sample approximates a systematic random sample of 430 farm households within the boundary of North and South Kyungsang Provinces (220 from Community Development village, 210 from Non-Community Development village), with 420 households sufficiently complete to process. Major findings of the study are summarized as follows: (1) Among the farmers in general, the adoption rate of agricultural innovation programs encouraged by the agricuiture supervising authorities seems to be very high. 18 items were used for this measure such as the planting of recommended seeds, the practice of seed sterilization, the use of weed spray before making the rice seed-bed, the use of vinyl cover on the rice seed-bed to keep the bed warm, the use of fertilizer at a proper time after transplantation, the spraying of preventive chemicals after transplanting, the spraying of a proper amount of preventive chemicals prior to the occurrence of large numbers of insects, the use of compost for rice growth last year, the practice of testing the degree of the acidification of the soil, early plantation of the rice plant, the renewal of rice seeds every three years, a deep plowing of the paddy-field, the adjustment of the amount of the use of nitrogenous fertilizer to prevent rice plant fever, the planting of bean plants along ridges between paddy-fields, and so on. In these 19 items, the rate of adoption of the innovations was higher than 70% for 13 items, and more than a half of the farmers respsnded positively for all of the items above except one, the practice of testing the degree of the acidification of the soil. In addition, the rate of the adoption of agricultural innovations is higher among the members of C·D village than members of Non-C·D village. (2) Farmers' living conditions seem to have been improved. Four of the six items such as replacement of thatch rooves by slate, fence and road repairs, and the modernization of the kitchen were adopted by more than a half of the farmers. Especially, more than 80% of the farmers showed favorable attitudes toward the items for the replacement of thatch rooves by slate and road repairs. And members of C·D village than those of Non-C·D village in general show a higher adoption rate for improving in their living conditions. (3) The rational life index measured by 16 items for the use or non-use of the farming plan mannual, subscription of a magazine on farming, listening to radio programs on farming, etc. seemed to be considerably high among the farmers surveyed in general. More than a half of the farmers adopted all the items. Higher rates of adoption of rational life techniques are seen among the members of C·D village. (4) The standard of living of the majority of the farmers has been improved since 1970. Higher improvement is seen among the members of C·D village. (5) Although 84.8% of the farmers have favorable attitudes toward family planning(C·D village: 88.1%, Non-C·D 81.2%), the proportion of actual practice of family planning among the farmers is much lower campared to their attitude. By camparison of two villages in terms of the knowledge about, attitude toward, and practice of family planning, much higher proportion of members of C·D village than those of Non-C·D village keep positive values. (6) Among the farmers, a great gap is found between the attitudes toward and practice of standardized and abridged procedures of family rites which are highly encouraged by the government. That is, most of the farmers regardless of the members either of C·D or Non-C·D, show a favorable attitude toward it, but a significant part of them hesitate to practice it. (7) Approximately 90% of the farmers participate at least in one group activity. (the rate of participation is slightly higher among tne members of C·D village than Non-C·D village.) (8) Achivement motivation in general is higher among the members of C·D than those of Non-C·D village. (9) Great change is seen in the farmers' traditional value orientation. Greater changes were found in C·D village than in Non-C·D village. This was measured by the examination of their attitudes toward such items as: fatalism, kinship ties, locality consciousness, dependency upon kinsmen, traditional distinction between the sexes, family determined marriage, preferential attitude toward boys, devination to decide if a proposed marriage is possible, seniority the idea of putting government officials above the citizens, the idea of distinction between the gentry and peasantry, dominance of men over women, magic, etc, Of the 12 items there has been least change in those items concerned with attitudes toward seniority and family determined marriage. (10) The rate of adoption of innovations among the farmers both cultural and technological is highly correlated with their acreage under cultivation. (11) Farmers who have a higher rate of adoption of innovations are more likely than those with a lower rate to have favorable attitudes toward improvement in their living conditions, rationalization of their daily life, and the participation in group activities. They also have a higher achievement motivation than those of the less adopting group. (12) When farmers were asked the meaning of the few Village Movement, the majority of them replied that it meant improvement in the living environment and an increase in income. (13) More than 90% of the farmers responded positively to the New Village movement since they were certain that it greatly contributed to development of their community.

Pollen Viability of Common Buckwheat (Fagopyrum esculentum Moench.) in in vitro Germination and its Application to Male Gametophyte Isolation

Woo, Sun-HeeㆍKeun-Yook ChungㆍHeung-Tae, KimㆍYong-Gu, ChoㆍHong-Sig, KimㆍBeom-Heon, Songㆍ Chul-Won, Lee and Seung-Keun Jong 忠北大學校 農業科學硏究所 2004 農業科學硏究 Vol.21 No.-

-본문참고-

파킨슨씨병 환자에 있어서 자가부신수질 이식술

정상섭,박상근,오성훈,김선호,윤도흠,박정수,양우익,최인준,안영수,김경환,박창일,김진수,이현철 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

Recent experimental studies and clinical cases have suggested that grafting tissue from the adrenal medulla into the brain may alleviate the symptoms of Parkinson's disease. Autologous adrenal medullary grafts into the striatum was performed stereotactically in two patients with Parkinson's disease. Both patients were bedridden preoperatively, but 4 months after the surgery both became ambulatory and one was even capable of returning to his job. Even though the number of cases was small⑵ and the follow-up period was short, this study shows that adrenal medullary transplantation into the striatum may have some beneficial effects in patient with Parkinson's disease. Further experimental and clinical trials are necessary to see whether this procedure will be a recommendable surgical treatment for patients suffering from Parkinson's disease.

대장암 환자에서의 담즙 암태아성 항원(CEA)

김종우,박용태,정철운,권성원,장항석,손석우,안대호,이경포 대한대장항문학회 2000 Annals of Coloproctolgy Vol.16 No.6

톨루엔 노출 근로자에서 유전자적 요인, 생활습관 및 식이가 요중 마뇨산 배설에 미치는 영향

임현우,박정일,노영만,이강숙,이정민,이원철,이세훈,정치경 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.3

목 적 : 본 연구는 생물학적 지표 특성 연구를 위한 단면조사 연구로서 톨루엔 노출과 톨루엔의 생물학적 모니터링으로 이용되는 요중 마뇨산 농도간의 양-반응 관계에서 효과 변경인자로서 작용하는 유전자 ALDH2, CYPIAI, CYP2El의 다양성 분포를 조사하고, 이들 유전자가 요중 마뇨산 배설 농도에 미치는 영향을 알아보고자 하였다. 방 법 : 연구대상자는 경인지역에 위치한 22개의 사업체에서 페인트 제조 72명, 제조업에서 도장작업 50명, 인쇄업 12명, 접착작업 12명, 벽지의 코팅작업 14명등 160명의 근로자이었다. 성, 연령, 유기용제 작업장 근무경력, 흡연습관, 음주습관, 검사일 이전 밤에 음주 여부, 시료 채취전 6시간 이내에 섭취한 식품조사, 측정일 개인보호구의 착용 여부에 대하여 설문조사를 시행하였다. 톨루엔에 대한 개인노출량은 passive air sampler로 측정하였고, 요중 마뇨산은 요중 크레아틴으로 보정하여 측정하였다. 또한 aldehyde dehydrogenase 2 (ALDH2) , cytochrome P45O IAI(CYPIAI), 그리고 cytochrome P45O 2El(CYPfEl)의 유전적 다양성은 혈액으로부터 백혈구의 DNA를 추출하여 제한 효소 절단 길이 다양성 (restiction fragment length polymorphism, RFLP)법으로 검사하여 다음의 결과를 얻었다. 결 과 : 연구대상자의 요중 마뇨산 농도의 기하평균은 0.44g/g creatinine, 기하표준편차 2.80이었다. 톨루엔 노출 농도, 개인 보호구 착용여부, 안식향산이 함유된 식품의 섭취여부중 요중 마뇨산 배설농도에 영향을 미치는 인자는 톨루엔 노출 농도뿐이었다. ALDH2, CYPIAI, CYPfEl, 연령, 흡연, 근무기간에서 회귀계수간에 차이를 보이는 경향이 있었다. 요중 마뇨산 농도에 대한 다중회귀분석에서 톨루엔, ALDH2, CYPIAI, CYP2El유전자형의 회귀계수가 통계적으로 유의하였다. 결 론 : 톨루엔 노출로 인한 요중 마뇨산 배설 농도는 ALDH2, CYPIAI, CYP2El유전자 다양성에 의해 영향을 받기 때문에, 유전자형의 대사능의 차이를 고려하여 마뇨산 기준 농도를 찾는 연구가 이루어져야 하겠다. Objectives The purpose was to investigate the distributions and the effects of genetic polymorphism of aldehyde dehydrogenase 2(ALDH2), cytochrome P45O IAI (CYPIAI), and cytochrome P45O 2El (CYPfEl) on the toluene metabolism. Methods : The subacts consisted of 160 workers who were exposed to toluene in different industries such as paint manufacturing, painting on steel and wood products, printing, bonding, and coating. The exposed toluene level was monitored by passive air sam paler, and the questionnaire variables were age, sex, smoking, drinking, previous night's drinking, use of personal protectlve equipment, work duration, and taking benzoic acid containing food. The urinary hippurric acid collected in the end of shift was corrected by urinary creatinine concentration. The genotypes of ALDH2, CYPIAI, and CYP2El were investigated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods with DNA extracted from venous blood. Results'The geometric mean and the geometric standard deviation of urinary hippuric acid concentration were 0.44 g/g creatinine and 2.80. The urinary hippuric acid concentration was significantly related to personal exposed toluene level among personal exposed toluene level, use of personal protective equipment, and benzoic acid containing food diet. The slope differences of the regression for ALDH2, CYPIAI, and CYP2E1 genetic polymorphism, age, smoking, and work duration tended to be significant. In multiple regression analysis, the regression coefficient of toluene, ALDH2, 7YPIAl, CYP2E1 genetic polymorphism were significant. Conclusions : From the above results, urinary hippuric acid level after toluene exposure was significantly affected by the genetic polymorphism of ALDH2, CYPIAI, CYPfEl. It is needed further investigation of the urinary hippuric acid level considering the effect of genetic polymorphism.

서울시 대기오염과 호흡기 질환 환자와의 관련성에 대한 시계열적 연구

최병철,구정완,박성균,임현우,이강숙,이원철,박정일 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 서울시의 대기오염 수준이 호흡기 질환 외래 환자수에 미치는 단기 영향을 파악하고자 하였다. 방법 : 1997년 7월부터 1998년 6월까지 서울시의 대기오염자료와 호흡기 질환에 대한 의료보험자료를 분석하였다. 추세변동과 기상요인, 요일 및 주별 효과등의 교란요인을 제어하고 관련성을 평가하기 위하여 generalized additive model(GAM)을 이용하였다. 결과 : 교란요인을 제어한 기본모델에 각 대기오염 물질을 포함시켜 분석한 결과, CO는 모든 연령층에서 일정하게 당일 농도가 가장 유의한 영향을 미치는 것으로 나타났고(RR=1.041∼1.051), NO₂역시 3일전의 농도가 모든 연령층에서 가장 유의한 영향을 미쳤다(RR=1.024∼1.050). O₃와 SO₂는 4일전 농도부터 당일 농도까지 지연시간이 길게 나타나는 특징을 보였으며, 15세 이하에서는 3일전 농도가(O₃RR=1.047, 95 % Cl=1.045∼1.049, SO₂RR=1.018, 95 % Cl=1.017∼1.020), 15-64fll (O₃RR=1.035, 95 % Cl=1.032∼1.037, SO₂RR=1.037, 95 % Cl=1.035∼1.039)와 65세 이상 (O₃RR=1.042, 95 % Cl=1.033∼1.051, SO₂RR=1,029, 95 % Cl=1.022∼1.036)에서는 당일 농도가 가장 유의한 결과를 나타냈다. PM□은 유의성이 낮게 나타났는데 15세 이하는 하루 전 농도(RR=1.011, 95 % 71=1.010∼1.013), 15∼64771(RR=1.021, 95 % Cl=1.019∼1.023)와 65세 이상(RR=1.025, 95 % Cl=1.018∼1.032)은 당일 농도가 유의하게 나타났다. 두 포염물질씩을 기본모델에 포함시켜 분석한 결과 CO, NO₂, O₃는 상대위험비가 '단일 오염물질모델'의 값과 거의 일정하게 통계적 유의성을 유지하였으나 SO₂는 15세 이하에서 NO₂와 같이 포함된 모델에서 통계적 유의성을 상실하였다. PM□은 모든 연령층에서 CO와 같이 포함된 모델에서 통계적 유의성을 상실하여 '단일 오염물질모델'에서 나타난 유의성이 CO에 의한 교란작용의 결과임을 알 수 있었다. 또한 15세 이하에서 NO₂, 15∼64세와 65세 이상에서 502와 같이 포함된 모델에서 역시 유의성을 상실하여 본 연구에서 살펴본 호흡기 질환에 미치는 PM□의 영향은 크지 않은 것으로 나타났다. 결론 : 본 연구의 결과는 서울시의 일상적인 대기오염이 여러 호흡기질환의 발생을 증가시킬 수 있음을 보여주었다. 따라서 대기오염의 효율적 규제에 대해 보다 적극적인 대책이 마련되어야 할 것이다. Objectives : This study was conducted to investigate whether air pollution levels in Seoul have short term effects on respiratory disease outpatients. Methods : We analyzed five air pollutants (CO, NO₂, O₃, SO₂, PM□) and daily counts of outpatient for respiratory disease divided by age group ((15yrs, 15-64yrs, 654yrs)during the period of July 1997-June 1998 using Generalized Additive Model (GAM) . Results : After controlling for seasonal trends, day of the week, week of the month, temperature and humidity, CO (RR=1.041 ∼1.051, 0-day lag) and NO₂(RR=1.024∼1.050, 3-day lag) were significantly associated with daily counts for respiratory disease in all age groups. O₃and SO₂were associated, with a 3-day lag in the age group under 15 years (O₃RR=1.047, 95% Cl=1.045-1.049; SO₂RR=1.018, 95% Cl=1.017-1.020) and with a 0-day lag in the age group 15 to 64 years (03 RR=1.035, 95% Cl=1.032-1.037; 502 RR=1.037, 95% Cl=1.035-1.039), in the age group over 65 years (O₃RR=1.042, 95% Cl=1.033-1.051; SO₂RR=1.029, 95% Cl=1.022-1.036). PMlo was weakly associated, with a 1∼day lag In the age group under 15 years (RR=1.011, 95% Cl=1.010-1.013) and with a 0-day lag in the age group 15 to 64 years (RR=1.021, 95% Cl=1.019-1.023), in the age group over 65 years(RR=1.025, 95% Cl=1.018-1.032) . In the' two pollutant model', the magnitudes of the recta alive risk for CO, NO₂nd O₃were maintained, but SO₂was not assoclated with daily counts for respiratory disease in the age group under 15 years after controlling for NO₂-PM□ was not associated in all age groups after controlling for CO, so the association with PM□ in the' single pollutant model' might be confounded by CO. In this study, the impact of PM□ on the respiratory disease was not large as compared with other pollutants. Conclusions : Air pollution in Seoul may Increase the Incidence of the respiratory disease, so more positive attention for the control of air pollution should be paid.

만성 정신분열병 환자에서 향정신약물에 의한 지속발기증 1례

김영철,정우식,우행원 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3

Haloperidol·thioridazine등의 향정신약물을 오랜동안, trazodone을 간헐적으로 복용해 오던 30세 미혼 남자 만성 정신분열병 환자에서 지속발기증이 생겨 비뇨기과에 응급으로 입원한 증례를 경험하였다. 지속발기증은 이들 약물이 발기감퇴(detumescence)에 필요한 말초 교감신경의 알파 아드레날린성 차단효과에 의해 생기기 때문에 이들 약물을 복합 사용할 시에는 지속발기증의 유무에 대해 관심있게 확인해야 한다. 심각한 부작용을 방지하기 위해서는 약물의 위험성을 알고있어야 하며 증상이 있으면 즉시 약물을 중단하고 비뇨기과 처치를 해야할 것으로 생각한다. Priapism is a rare but serious adverse effect of psychotropic medication from their peripheral alpha-adrenergic blocking action, perhaps directly blocking the sympathetic impulse for detumescence. Ont patient with chronic schizophrenia who admitted at urologic department developed this side effect during treatment with oral antipsychotics, thioridazine, haloperidol and antidepressant, trazodone. Awareness of these association and serious consequences of this disorder may be helpful to clinician in choosing psychotropic medication that minimize the risk of developing priapism.

백서에서 신 허혈성 손상에 미치는 칼슘 길항제의 효과

문철웅,정종훈,박천국,이승일,배학연,장경식,김만우,정춘해,홍순표,이병래,김호중 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Renal ischemia is one of the most common causes of acute renal failure. Four factors related to the pathogenesis of acute renal failure are vasoconstriction, decreased glomerular filtration rate, tubular back leak of filtrate, and intratubular obstruction. The cellular response to renal ischemic insults include decreased content of adenosine trihosphate, lipid peroxidation induced membrane degradation, alteration in cellular pH, and calcium or phospholipase induced mitochondrial dysfunction. Much attention has been given to the role of increased cellular calcium as a pathogenetic contributor to cell injury during ischemia. Author studied the protective effects of calcium antagonists on cellular injury during renal ischemia in rat. To investigate the protective role of these agents, author measured the amount of malondialdehyde(MDA) and the enzyme activities of free radical scarvengers-superoxide dismutase(SOD), catalase and glutathione peroxidase from non-pretreated group and calcium antagonists pretreated groups in control, ischemia and reflow subgroups. The results were summerized as follows: 1) The amount of MDA in non-pretreated group was higher in the reflow compared with the control(<p<0.01). But, in all pretreated groups, there was no statistically difference in the amount of MDA. 2) The SOD activity in non-pretreated group was lower in both the ischemia and the reflow compared with the control (P<0.05). But, in both verapamil and trifluoperazine-pretreated groups, there was no statistically difference in the SOD activity. 3) Both catalase and glutathione peroxidase activities in non-pretreated group were lower in both the ischemia and the reflow compared with the control (P<0.05). But in all pretreated groups, there was no statically difference in both catalase and glutathione peroxidase activities. These results suggest that free radical mediated ischemic injury by renal artery clamp in rat can be protected by intraperitoneal pretreatment with calcium antagonists. As trifluoperazine has a protective effect in renal ischemia, the calcium activated calmodulin dependent enzyme may play a role in renal ischemic injury.

Brushless 同期發電機의 特性에 關한 硏究 : 主로 自勵型 Brushless 單相同期發電機의 應用에 對하여

宋鐵,鄭憲相,李愚宣 朝鮮大學校 1977 綜合論文集 Vol.1977 No.-

As an excitation system of the synchronous generator, an exciter which is directly connected to the main shaft, comprising some restrictions by the increasing capacity under the condition of commutation, has generally been used. In order to solve the restriction problem as well as to operate the generator without difficulty, it is desired to get rid of electrical sliding contacts such as brush and slip ring. To eliminate these electrical sliding contacts, several types of brushless generators have been developed, one of which being understood to be the self-excited brushless single-phase synchronous generator. In this paper, the results of experimental test about the characteristics are analyzed. There are not a few possibilities in the CT connection wherein the load current affects the exciting current.