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화학-기계적 우식 제거법을 이용한 유구치 우식의 치료 : 증례보고
이혁상,이재천,김영재,김정욱,김종철,장기택 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2
전통적인 bur에 의한 우식치질의 삭제는 진동과 열에 의한 자극을 초래하기 때문에 아이들은 치과에 가는 것을 무서워 한다. 최근 전통적인 방법을 대체하는 방법을 개발하려는 노력이 이루어져 왔고, 화학-기계적인 우식 제거법 역시 이러한 시도 중 하나이다. Carisolv^(TM)는 세가지 아미노산과 낮은 농도의 sodium hypochlorite, 그리고 특별하게 고안된 수 기구로 구성된 제품이다. 본 증례는 Carisolv^(TM)로 치료한 두 증례를 보고한다. 우식 상아질을 Carisolv^(TM) gel과 기구로 제거하고 복합레진으로 수복하였다. The conventional drilling method of caries removal makes vibration and thermal stimuli, so that children are afraid of dental treatment. Recently, various non-invasive caries removal techniques of alternatives to traditional methods are introduced and chemo-mechanical canes removal is one of them. Carisolv^(TM) comprises a gel that is composed of three different amino acids and a low concentration of sodium hypochlorite and specially-designed hand instruments. This report describes two cases of dental caries treatment with Carisolv^(TM). The carious dentin was eliminated with Carisolv^(TM) gel with instruments and then composite resin restoration was conducted.
Coexistence of Porokeratosis of Mibelli and Disseminated Superficial Actinic Porokeratosis ( DSAP )
Kim, Ki Sung,Kim, Joo Won,Song, Hae Jun,Oh, Chil Hwan,Kim, Chong Hyeok 대한피부과학회 2000 Annals of Dermatology Vol.12 No.2
There have been several reports of more than one type of porokeratosis occurring in the same family or the same individual. We hope to support the view of different phenotypic expressions of a common genetic aberration by describing an additional case of porokeratosis of Mibelli on the perianal area and DSAP on the face, forearms occurring in a 45-year-old man.
Ki - 1 positive large - cell lymphoma ( Ki - 1 LCL )
김종혁(Chong Hyeok Kim),이성렬(Seong Yeol Lee),오칠환(Chil Hwan Oh) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.3
In 1985, Stein et al, indentified an anaplastic large-cell malignant lymphoma that was distinctive because of the diffuse dermal infiltration of pleomorphic large lymphocytes, sinus growth pattern, and reactivity with the monoclonal antibody Ki-1(CD30). The clinical feature; distinguishing anaplastic large-cell Ki-1 lymphoma include a young median age, frequent peripheral adenopathy with sparing of the mediastinum, and extranodal disease with skin the most common sitc of involvement. We report a case of Ki-1 postive large-cell lymphoma in a 74-year-old male patient who presented with multiple ulcerated nodules on the right shin area. (Kor J Derrnatol 1903; 31(3): 444-448)
Sodium Fusidate ( FucidinR 연고 ) 에 의하여 발생한 접촉 피부염 2예
김종혁(Chong Hyeok Kim),오용섭(Yong Sub Oh),홍승현(Seung Hyun Hong),계영철(Young Chul Kye),문기찬(Kee Chan Moon) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.6
Sodium fusidate, obtained by fermentation of the fungus, Fusidium coccineum, has a steroid structure and shows a very high antitaphycoccal activity. The allergic potentirl of sodium fusidate is low and few cases of contact allergy to sodium fusidate have been reported. We present two cases of allergic contact dermatitis to Fucidin cintentione developed postoperative dressing of a skin biopsy and the other after laser treatment of a vascular nevi. The patch test results showed positive reaction to sodium fusidate in both cases. (Kor J Dermatol 1993;31(6):944-947)
김종혁(Chong Hyeok Kim),김준영(Jun Young Kim),문기찬(Kee Chan Moon),김수남(Soo Nam Kim) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.1
Eccrine epithelioma is an exceedingly rare cutaneous tumor ancit is believed to represent the maligant counterpart of the eccrine dermal syringoma. It occirs as an infiltrating basaloid growth, usually on the scalp or head, that frequently recur, apparrntly because of inadequate excision. We report a case of this tumor in a 60-year-old female, who showed a well demarcated, tender nodule on her left parietal scalp which had been present for three years. Histopat.hologically, the tumor was composed of strands of darkly staining epithelial cell embedded in a dense fihrcus stroma with ductal differentiation and cyst formation (Kor J Dermatol 1992; 30(1): 122-125)
염증 및 각화 이상 소견을 보이는 피부질환에서 Elafin 단백질의 발현 양상과 그 의의에 대한 연구
김종혁(Chong Hyeok Kim),송해준(Hae Jun Song),김수남(Soo Nam Kim) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.12
Background:Elafin is a serine proteinase inhibitor first discovered in keratinocytes from psoriatic epidermis. The molecular structure of elafin contains two different functional domains; one for the proteinase inhibitor, which is directed against elastase and proteinase-3, and the other for transglutaminase substrate. As this unique structural characteristic implies, elafin would be expected to have two distinct biologic functions in tissues. But, the roles and biological features of elafin have not been extensively studied in the skin. Objectives:This study was designed to demonstrate the immunohistochemical localization of elafin in inflammatory and keratinizing skin disorders, and to elucidate its biological functions. Materials and methods:The pre-elafin sequence was amplified by PCR using a human epidermal cDNA library and expression construct which was ligated into an expression vector. Then, the expressed proelafin sequence was purified and injected intradermally into rabbits to raise a polyclonal antibody. The skin biopsy samples of various skin diseases and normal controls were used for immunohistochemical staining to detect elafin expression. Results:1)Expression of elafin was observed in infected epidermis, and is believed to be involved in the defense mechanism of the skin. 2)In dermal and subcutaneous inflammatory diseases, epidermal elafin expression was influenced by the location of the inflammation. 3)Elafin was expressed in bullous dermatoses accompanied by acantholysis or spongiosis of epidermal cells. 4)Expression of elafin was upregulated in papulosquamous skin diseases which was characterized by epidermal hyperplasia and abnormal differentiation. 5)Elafin was expressed in keratinizing skin diseases that was accompanied by abnormal differentiation of epidermal cells. 6)Expression of elafin was demonstrated in skin tumors that showed proliferation of suprabasal cells. The intensity of (Korean J Dermatol 2000;38(12):1603~1614)