홍당무 모자이크바이라스에 관한 연구

김은수(Woon Soo Kim),최예진(Yae Chin Choi) 한국식물학회 1963 Journal of Plant Biology Vol.6 No.2

KIM, Woon Soo* & CHOI, Yae Chin**(University of Ill., U.S.A.* & Chunchon Agricultural Coll.**) Studies on the viruses of radish mosaic. Kor. Jour. Bot. VI (2):9-21, 1963. A mosaic diseased radish collected from the suburb of Seoul, in November, 1961 was used for studing the host range, physical properties, purification, insect transmission, and electron microscopy. A Japanese strain of raddish mosraic (RPV) was also used with Korean strain of radish mosaic (KRMV) for a comparative study. The two viruses, KRMA and RPV, were identified by the difference in host range, insect transmission and electron microscopy. The KRMA was severely infective on tobacco and Nicotiana glutinosa, while on Gomphrena globosa was immune to the virus. RPV produces necrotic local lesions on Comphrena globosa but did not infect tobacco and N. glutinosa. Among varieties of radish, Seoul, Akamaroo, Akanagea, Koong-Joong showed more severe symptoms than Simoo, Minong, Paek-soo, which appeared to be fainly resistant. In a number of tests, it was found that the virus KRMA retained its infectivity until to a dilution of 1:2,000, heating at 58˚C for 10 minutes, and aging in vitro for 7 days at room temperature. The RPV was not inactivated until it was diluted to 1:2,000, heated to 56。C, and aged for 6days. The KRMV was readily transmitted by the aphid (Myzus persicae Sulz). The virus RPV was not transmitted by the aphid in a number of tests. Partialy purified viruses using ammonium acetate buffer, salting-out by ammonium sulfate and centrifugation of high and low speed were highly infective. Electron micrographs showed that the KRMV paticles are of spherical particles whereas the RPV particles are rod-shaped.

하순 및 하악골 정중열의 치험례

차두원,김현수,백상흠,김진수,변기정 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

Median cleft of the lower lip and/or mandible is a rare congenital anomaly, first mentioned by Couronne in 1819. Monroe(1966), Fujino(1970), Ranta(1984) and Oostrom(1996) conducted comprehensive reviews and list cases in literature. Median cleft varies greatly, from a simple vermilion notch to a complete cleft of the lip involving the tongue, the chin, the mandible, the supporting structures of the median of the neck, and the manubrium sterni. The associated anomalies include ankyloglossia, cleft tongue, neck contraction, heart lesion, absence of hyoid bone, and so on. The etiology of median cleft is unknown. Various possibilities, such as failure of mesodermal penetration into the midline, failure of fusion of mandibular processes, external factors apart from the embryogenic pattern such as prensure, position in utero, circulatory failure caused placental adhesion, diseases in pregnancy, and so on, have been discussed. A 8-year-old girl was referred to the Dept. of Oral & Maxillofacial Surgery, Kyungpook National University Hospital and had been aware of the fact that at birth "she had something wrong with her mouth." Shortly after birth she had been examined by a plastic surgeon and at that time surgical procedure had been performed to release the tongue from the lower jaw and lip at local hospital. On admission, she had a slight notching of lower lip and two fibrous frenum ran from the lip along the ventral surface of the tongue, diastema between her mandibular central incisors, and slightly constricted bifid mandible associated independent movement of the two halves of mandible. The patient had autogenous iliac bone graft to reconstruct the mandibular midline defect. The postoperative result was uneventful. In future, the correction of the soft tissue deformities such as notching of the lower lip and partial ankyloglossia will be required for the esthetic and functional improvement.

양측성 Warthin씨 종양 치험례

김상규,우길상,김진수,변기정 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3

Warthin's tumor is a bunign neoplasm that occurs almost exclusively in the parotid gland. The tumor most frequently occurs in the tail of the parotid near the angle of the mandible. One unique feature of Warthin's tumor is the tendency of bilateral occurrence, which has been noted in 4 to 7 percent of cases. Most of these bilateral tumors do not occur simultaneously but are metachronous(occurring at different times). Histologically the tumor is composed of a mixture of ductal epithelium and a lymphoid stroma. Surgical removal is the treatment of choic for patients with Warthin's tumor. Warthin's tumor seldom recurs after removal. In our department, a 50-year old man, diagnosed as Warthin's tumor by fine needle aspiration biopsy, was treated by superficial parotidectomy on right side and subtotal parotidectomy on left side. For the treatment of Warthin's tumor, correct pretreatment diagnosis and the selection of appropriate surgical methods are important. We present a case report of the bilateral Warthin's tumor with the review of literatures.

백서 좌골신경에 Glycerol이 미치는 조직병리학적 변화

김태주,김진수 慶北大學校 齒科大學 1990 慶北齒大論文集 Vol.8 No.1

The purpose of this experimental study was to examine and compare the histological changes when anhydrous glycerol and normal saline applied to the sciatic nerves of rats perineurally in vivo. For this study, 30 Sprague-Dawley male ablino rats were used as the experimental animals and divided into 6 groups. The topical application of anhydrous glycerol on the right nerve of rats for 1 day, 3 day, 1 week, 2 week, 3 week and 4 week were used in experimental groups Ⅰ,Ⅱ,Ⅲ, Ⅳ,Ⅴ,Ⅵ. Physiological saline on the opposite site was the control in groups Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ. The animals were sacrified on the 1st and 3rd day, 1st, 2nd, 3rd, 4th weeks after experimentals and all specimens were fixed in 10% neutral formalin and 1% osmium tetroxide solution after, embedded in paraffin was and cross-sectioned with 4㎛. After these procedures, specimens were observed under the light microscope. The results obtained were as follows: 1. Our reselts show that myelin disintegration and axonolysis occur with glycerol application. 2. The degree of histological damage is proportional to the depth of penetration, and the fibers colsest to the perineurium showing maximal damage. 3. The maximal destruction of myelin were noted at one or two weeks. 4. There is no evidence of selective destruction of any groups of axons depending upon the degree of myelination, although myelin sheath shows the most striking histological change. J. Kyungpook Not. Univ. Sch. Dent. Vol.8, No.1, 51∼61, 1991.

임상소견에 따른 법랑모세포종의 방사선학적 특징에 관한 임상통계학적 분석

김진수,신상욱,박노부 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.4

The author studied on the 115 cases of the ameloblastoma which had been diagnosed with biopsy during the period of 1962 to 1994 at the Kyungpook National University Hospital, Pusan National University Hospital, Youngnam University Hospital, Keimyung University Hospital, Catholic Medical School Hospital, and Maryknol Hospital. This study contains the statistical analysis of the clinico-pathological findings such as sex, age, location, chief complaint, duration, treatment method, size, recurrence and impacted teeth in relation to radiographic findings. The results were as follows : 1. The incidence rate was 60% in .male and 40% in female. 2. At the time of diagnosis, the age of the patients ranged from 9 to 69 years old (average 31.4 years old). The cases of 73% were in the 2nd, 3rd and 4th decades of life. 3. The majority of cases, 88.7% occurred in the mandible, especially 59% in the mandibular angle area. 4. The most prevalent chief complaint of swelling was 56.5%. 5. As regards duration, the cases less than 12 months appeared 49.5%, and average duration is 30.45months. 6. Unilocular radiographic findings showed 43.5%, Multilocular radiographic findings appeared 56.5%. 7. Conservative treatment was performed 40.0%, and radical treatment was employed 60.0%. 8. There was the variation of lesional sizes between 2.0cm and 15cm, average size 6.19cm. 9. Recurrent cases were 28.7%, and impacted teeth were shown 30.43%. 10. The ratiographic finding has no relationship with the factors of age, location, chief complaint, recurrence and impacted teeth, however there is slight indication that the below 30-year-old patient tend to be related to the multilocular type. 11. The multilocular radiographic findings were shown more frequently in the groups of females, over average of 30.45 months, over average size of 6.19cm and radical treatment.

Slim Patch Type을 이용한 카페인의 경피흡수에 관한 연구

김정수,권동환,임도형,김구서,강진양 한국약제학회 2006 Journal of Pharmaceutical Investigation Vol.36 No.2

DESMOPLASTIC AMELOBLASTOMA의 치험 1례

김성국,신홍인,박희경,장현중,김영미,김진수 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

Ameloblastomas are benign epithelial neoplasm of the jaw comprising approximately 1-3.3% of all odontogenic cysts and tumors. Although most are microscopically benign, they are generally considered to be locally aggressive and destructive, exhibiting a high rate of recurrence. Treatments of them contain the conservative treatments on unilocular types and radical treatments on multilocular types. Classifications based on the histologic features of ameloblastoma generally included the follicular, plexiform, acanthomatous, basal cell, uncystic types. However, recantly a new and unusual variant has been added by Eversole et. al in 1984, the histologic features of which are characterized by marked stromal desmoplastic proliferation. This is a case report of desmoplastic ameloblastoma in the anterior maxilla of 63 year-old female treated by block excision. THis provides a brief review of the literature because of the rarity and unusual radiographic-histologic features of desmoplastic ameloblastoma.

Island Flap을 이용한 구강상악동누공의 치험례

김진수 慶北大學校 齒科大學 1986 慶北齒大論文集 Vol.3 No.1

This is to report a case of oroantral fistula closure by palatal island flap technique. The patient, 54 years old female, had an oroantral fistula on the buccal surface on the area of right upper fistula molar. The author noticed the following advantages. 1. It is a one-stage local flap procedure that provides excellent blood supply and adequate bulk and length. 2. It has good mobility and avoids venous congestion associated with bunching and tethering of the palatal tissue. 3. It is possible that the author con perform the prosthodontic treatment without secondary operation for vestibular extension.

우라늄오염에 의한 신부전증에 미치는 제염제의 방호효과

김태환,정인용,김성호,김경중,방효창,류성렬,진수일 대한방사선 방어학회 1990 방사선방어학회지 Vol.15 No.2

원자력산업의 시설증대로 우라늄 오염의 가능성이 증가되고 있음에도 불구하고 종사자 및 국민에대한 안전대책 및 의료적 처치에 관한 연구가 매우 미흡한 실정에 있어 이에 대한 응급처치방안을 수립코자 우라늄을 투여한 후 제염제를 투여하여 관찰하였던 바 다음과 같은 결론을 얻었다. 1. 우라늄오염에 의한 체중변화에 미치는 제염제의 영향에 있어서 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol을 투여한 군에서는 우라늄단독투여군에 비해 체중이 현저하게 증가하였다. (P<0.05). 2. 모든 실험군은 우라늄오염에 의한 음수량과 배뇨량의 변화를 유의성 있게 호전시켰으며(P<0.05), 특히 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol을 투여한 군이 가장 높은 증가경향을 나타냈다(P<0.05). 3. 우라늄오염에 의한 BUN농도 변화에 미치는 제염제의 효과는 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군이 공히 우라늄단독투여군보다 BUN농도가 매우 감소되었다(P<0.01). 4. 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군은 우라늄오염에 의한 serum creatinine의 농도증가를 유의하게 감소시켰으나 (P<0.01), sodium bicarbonate와 생리적 식염수를 병행투여한 군은 다소 감소하는 경향으로 나타났다. 5. 우라늄오염에 의한 urine creatinine농도 변화에 미치는 제염제의 효과에 있어서 sodium bicarbonate와 생리적 식염수를 병행토여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군에서는 우라늄단독투여군에 비해 creatinine의 배설이 상당히 증가하였다(P<0.05). 6. 우라늄오염에 의한 신장의 소견에 있어 우라늄단독투여군은 근위곡세뇨관상피의 공포화 및 종창, microvilli와 brush border의 손실, 세뇨관 상피의 괴사가 관찰되었으며, 간장의 충혈, 중심성 괴사 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군에서는 우라늄단독투여군에 비해 높은 방호효과가 관찰되었으나 다른 실험군에서는 큰 효과가 없는 것으로 나타났다. 결론적으로 우라늄의 체내오염시에는 sodium bicarbonate와 생리적 식염수를 가능한 빨리 병행투여하거나 dithiothreitol을 체내오염후 30분이 지나서 투여하는 방법이 우라늄오염에 대한 제염에 매우 유효할 것으로 생각되며, 특히 우라늄에 의한 인체장해를 유의하게 경감시켜줄 것으로 사료되었다. Appreciable radiation exposures certainly were occurred m the reactor burn-up, the nuelear fall-out and the surroundings of nuclear installations with radioactive effluents. Therefore ,radioactive nuclides is not only potentially hazardous to workers of nuclear power plants and related industrials, but also the wokers who handle radioactive nuclides in biochemical research and nuclear medicine diagnostics. And in the case of occurring the nuclear accidents, the early medical treatment of radiation injury should be necessary but little is established'medical procedures to decontaminate the victims of internal contamination of radioactive nuclides in korea. Accordingly, to achieve the basic data for protective roles and medical treatment of radiation injury, the present studies were can-id out to evaluate the decontamination of uranium by the chemical drugs. The results observed were summarized as follows : 1. The combined treatmet group of sodium bicarbonate and saline with uranyl nitrate injection simultaneously and the dithiothreitol group that was administered 30 minutes after uranyl nitrate injection were increased significantly in the change of body weight than uranyl nitrate-only group(P<0.005). 2. All the experimental groups were increased the fluid intake and urine volume on the uranyl nitrate-induced acute renal failure, but the combined treatment group of sodium bicarbonate and saline with uranyl nitrate injection simultaneously and the dithiothreitol group that was administered 30 minutes after uranyl nitrate injection have the higher increment of fluid intake and urine volume(P<0.05). 3. When sodium bicarbonate and saline was treated with uranyl nitrate injection simultaneously, and dithiothreitol was administered 30 minutes after uranyl nitrate injection, there was significantly reduced in BUN concentration (P<0.0l). 4. When dithiothreitol was administered 30 minutes after uranyl nitrate injection, there was reduced more significantly on the increment of serum creatinine concentration than that observed in uranyl nitrate-only group(P<O.Ol). but when the combined treatment of sodium bicarbonate and saline with uranyl nitrate simultaneously, there was still, albeit much less marked, decrease in serum creatinine concentration. 5. The sodium bicarbonate and saline was treated with uranyl nitrate simultaneously and dithiothreitol was administered at 30 minutes after uranyl nitrate were excreted markedly higher urine creatinine concentration than the uranyl nitrate-only group. 6. Uranyl nitrate has been used in experimental animals to produce hydropic degeneration and swelling of proximal tubules, disappearance of microvilli and brush border or necrosis in the kidney and centrilobular necrosis, congestion, and telangiectasia of the liver. When the sodium bicarbonate and saline was treated with uranyl nitrate simultaneously, and dithiothreitol was administered 30 minutes after uranyl nitrate, there was more marked the protective effect than uranyl nitrate-only group. Finally, if the sodium bicarbonate and saline may administered as quickly as possible each time that some risk for internal contamination with uranium, and dithiothreitol is administered 30 minutes after uranium contamination, there ameliorates the course of uranyl nitrate-induced acute renal failure,and this effect is assocciated with prevention of uranium (heavy metal) induced alterations in BUN. serum creatinine. urine creatinine. fluid intake, urine volume and body weight.

청소년의 가정환경과 도덕발달단계가 행동장애에 미치는 영향

진태원,이흥표,김사준,조수철 대한소아ㆍ청소년정신의학회 1997 소아청소년정신의학 Vol.8 No.2