만성 췌장염에 의한 십이지장 협착 1예

서백종,장기육,박용근,채현석,한석원,이창돈,정인식,차상복,박두호 대한내과학회 1997 대한내과학회지 Vol.53 No.3S

저자들은 만성췌장염환자에서 지속적인 오심과 구토를 주소로 내원하여 십이지장협착으로 진단된 1예를 경험하였기에 보고하는 바이다. Duodenal stenosis resulting from fibroinflammatory process is a rare complication of chronic pancreatitis. The mechanism of duodenal stenosis seems to be related to ischemia and edema caused by persistent inflammation, which results in irreversible change of duodenal wall structure. We experienced a chronic alcoholic male patient with duodenal stenosis who had a history of choledochojejunostomy to relieve distal bile duct stenosis several years ago. He had suffered persistent postprandial nausea and vomiting for several months. Barium study of upper gastrointestinal tract and repeated endoscopy show narrowing lumen of duodenum with coarse nodular surface due to reactive inflammatory change.

임신 및 출산후 흰쥐 자궁의 Catecholamine 형광물질의 변화에 관한 연구

승경록,서영석,엄창섭 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1

This study was undertaken to investigate the pattern of distribution of adrenergic nerves in normal virgin, and the relatioships between the functions of adrenergic nerve and the female sex hormones changed peculiarly during pregnancy and post partum as previously reported by many authors. The reproductive organs were fixed in mixture of 4% formaldehyde and 0.5% glutaraldehyde and processed for fluorescent microscopy to show the catecholamine concentrations in nulliparous, pregnant(5, 10, 15 and 20 days), puerpheral(3, 7 and 15 days),and primiparous (30 to 45 days after parturition) rats. The result obtained in this investigation are summarized as followings. 1. In virgin uteri, catecholamine-fluorescence was visible intensely in the wall of vessels and their surrounding connective tissue and less intensely in myometrium than the vessels in all regions of reproductive tract. The intensity of fluorescence was higher In uterine cervix and tubal end of uterine horn than the main part of uterine horn. 2. In the pregnant uteri, the intensities of fluorescence did not changed at 5 days of pregnancy, but decreased gradually from 10 days to 15 days of pregnancy, and disappeared atmost completely in myometrium and small vessels except some of large vessels in perimetrium during the late pregnancy. 3. In lactating rats after parturition, the fluorescence was increased rapidly and almost completely restored by 15 days after parturition. 4. In the parous uteri at more than 30 days after parturition, the fluorescence showed slightly more intense than that in the nulliparous uteri. The above findings suggest that the alterations of catecholamine-fluorescence are much removed from the peculiar characteristic changes of the female sex hormonal levels during pregnancy and post partum. It is concluded that the alterations of catecholamine-fluorescence closely relate with the quantitative changes of uterine tissue during pregnancy and post partum, and having the experience of pregnancy and parturition, the uterus attain to maturity.

난치성 만성정신분열증 환자의 생활의 질에 미치는 정신사회치료 프로그램의 효과에 대한 예비연구

송동호,배민진,이종호,이홍식,김선경,서호석,김찬형,전지용 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : Recent studies of psychosocial adjustment after hospitalization have found that the combination of maintenance antipsychotic drug treatment and psychosocial treatment including psychoeducational program are highly predictive of social rehabilitation and reduction of subsequent relapse. Two groups of patients with refractory chronic schizophrenia were preliminarily compared to determine the effect of a psychosocial treatment program on the quality of life in refractory chronic schizophrenics in an open comparative trial. Methods : One group(N=11) was assigned to approximately six months of the psychosocial treatment program(including psychoeducation program and activity program such as interpersonal relationship program, social skill training, self management program, outings, etc), in a group format, twice a week and a fixed maintenance dosage of clozapine ; while scale(QLS) was used to provide an objective measure of changes in patient's psychosocial functioning and a general assessment of psychopathology was made using the Brief Psychiatric Rating Scale(BPRS). Results : Both BPRS total positive score and the QLS total score, especially in the intrapsychic foundation factor of the scale showed a statistically significant improvement in the psychosocial treatment group. But there was no significant change in both BPRS and QLS scores over a 6-month period in the non-psychosocial treatment group. A significant negative correlation was found between the negative symptom and changes of QLS total, instrumental role and common object and activities scores respectively after receiving a 6-month of the psychosocial treatment program. Conclusion : These results suggest that a psychosocial treatment program including the integration of psychoeducation and a skill training oriented activity program serve as an outpatient treatment modality to improve the quality of the life in refractory chronic schizophrenia. To further clarify the effect of psychosocial treatment in chronic schizophrenia, a randomized trial should be done.

고관절 전 치환 성형술 후 탈구에 관한 치험 및 연구

서유성,김동진,박종석,임수재,나수균,최창욱 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Dislocation is one of the serious complications in total hip replacement arthroplasties. The purpose of this study is to evaluate the risk factors of dislocation, including age, sex, preoperative diagnosis and bilaterality, history of previous hip surgery, positioning of component, soft tissue tension, treatment after dislocation or redislocation. Authors reviewed 190 patients of total hip replacement arthroplasty, which were performed from Jan. 1990 to Dec. 1996. 15 cases developed dislocation after surgery. Incidence of dislocation was 7.89%(15 of 190 cases). Dislocation after revision was not happened(0 of 18 cases). Inclination of acetabular cup was average 37.5° (range: 31° - 43° ). Average anteversion of the acetabular component was 18.1" by Woo and Morrey method, 11.4° by Hassan method. They were normal range except 3 cases. Dislocation was not prevented even though inclination and anteversion of acetabular cup were within normal range. Soft tissue tension is determined by change of limb and femoral neck length. Average limb length difference was -0.2mm(range; -l0mm - +10mm) and average offset difference was +1.7mm(range;-4mm - +18mm). Revision must be accomplished as soon as possible when limb shortening happen by upward migration of the acetabular component. In conclusion, anteversion of acetabular cup may be most important factor in our cases, so cup position must be fixed in proper position during operation.

老化過程에서 흰쥐 滑車神經의 軸索의 數 및 直徑의 變化

최영수,엄창섭,서영석 최신의학사 1987 最新醫學 Vol.30 No.8

동시배양한 흰쥐 척수앞뿔신경세포-근육세포 접촉부위에서의 신경결합물질의 분포

엄창섭,서영석 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.4

제 2형 당뇨환자들을 대상으로 측정한 N-acetyl-β-D-glucosaminidase검사의 임상적 의의

전창호,서헌석 대한임상병리학회 1997 대한임상병리학회지 Vol.17 No.1

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

Silent Discharge와 TiO₂광촉매 산화반응을 이용한 VOCs 처리

박석출,정창훈,서정민,최금찬 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.2

This study has been carried out for evaluation of VOCs treatment let out at the industrial field using a silent discharge process through process approvement and TiO₂ photocatalytic oxidation. And it was presented experimental results on the silent discharge plasma and TiO₂ photocatalytic oxidation processes at atmospheric pressure gas streams containing diluted concentrations of benzene, toluene, and xylene out of VOCs. It has shown that each concentration, background gas, flowrate, and applied power have effected on three materials decomposition and byproduct distribution. Analyses of benzene, toluene, xylene and byproduct concentration was carried out by GC-FID.

세포화학적 방법에 의한 흰쥐 상경교감신경절의 전자현미경적 연구

엄창섭,서영석 고려대학교 의과대학 1990 고려대 의대 잡지 Vol.27 No.1

The superior cervical sympathetic ganglion of the adult male Sprague- Dawley rats were observed electron microscopically using the routine method, Ca^(++) - ATPase and Na^(+) - K^(+) ATPase ultrocytochemistry and tannic acid ringer incubation method. The results obtained were as followings. The ganglion cells of the superior cervical ganglion appeared to be two types in urethane-anesthetized, 3% giutaraldehyde-fixed animals, One type was larger in size and had lightly stained cytoplasm. The other type was smaller in size and had darkly stained cytoplasm. In other cases, both types of cells were stained lightly. The surfaces of the ganglion cell bodies and processes were covered with thin processes of the satellite cells except small areas where synapses occurred. In some areas, the processes of the satellite cells were present in several layers. The parts of the ganglion cell bodies where the processes arised had more dense materials in the cytoplasm which extended into the ganglion cell processes. The intercellular spaces between the ganglion cells and the satellite cell processes were filled with dense amorphous materials with similar densities to those in the ganglion cell bodies and processes. Their density showed decreasing ~ tendency from the inner narrower intercellular space to the wider spaces. And, the darkly stained cell processes was invading deep into the ganglion cell body with several layers of satellite cell coverings. The cytoplasm of the satellite cells was stained more darkly than that of the ganglion cells. Some omega figures containing darkly stained materials that was thought indicative of the endocytotic processes were present in some areas of the plasmalemma. The reaction products of Ca^(++)-ATPase were present along the outer surface of the piasmalemma of both ganglion cells and satellite cells. Almost all intracellular organelles were negative for Ca^(++)-ATPase except intermediate reactions in the tubular agranular endoplasmic reticulum of the ganglion cells. These tubular structures were opened directly to the surface of the ganglion cells. Some satellite cells showed widely spread reactivity throughout the cytoplasm. Na^(+)-K^(-) ATPase reactivity was also present along the plasmalemma of ganglion cells and satellite cells but the reaction was weaker than that of Ca^(++)-ATPase. Agranular endoplasmic reticulum of the both cells had reaction products in their cisternae. Some weak reactions were recognized in the Golgi complex. Mitochondria in the ganglion cell bodies and satellite cell showed no evidences of enzyme reaction, but those in the distal parts of the ganglion cell processes had reaction products between the inner and outer membranes. Synaptic vesicles were generally free of reactions, however in cases where the reactions occurred all the clear vesicles, but no dense cored vesicles, showed positive reactions. Nuclei of some satellite cells showed strong Na^(+)-K^(+) ATPase activities. The secretory materials reacted with tannic acid appeared in the intercellular spaces between Lhe ganglion cells and satellite cells. Some tubular agranular endoplasmic reticulum of the ganglion cell body contained dense materials. This may mean that these tubules are connected to the exterior of the cells. In conclusion, we thought that there must be some mechanisms to secrete materials which use tubular endoplasmic reticulum instead of secretory vesicles or to transport materials through the plasmalemma directly. Ca^(++)-ATPase may play some roles in the above processes, but Na^(+)-K^(+) ATPase may be involved in the recruitment of secretory materials after the depolarization or the secretion had had occured. Multi-layered satellite cell processes may play important roles in the regulation of the gacglion cell functions.