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睦榮一,許炳琪 亞洲大學校 1988 論文集 Vol.11 No.-
Use of iterative stepwise methods has been a common practice in designing multicomponent distillation columns. Sometimes, it is difficult to justify iterative calculations from the point of view of cost-effectiveness, particularly when the input information does not have precision or accuracy, or when one simply does not have sufficient information for the system under study. In this work a new method was proposed which permits quick and simple procedures giving rise to values of 14 different parameters needed for the design of a column for a multicomponent distillation Several simplifying assumptions are made in the course: the usual one of a quasibinary in which the average relative volatility of the light key referred to the heavy in the bottoms and the light key referred to the heavy in the bottoms and the light key referred to the heavy in the distillate, Prater and Boyd's approximaton for column efficiency, approximations for expedience that arise in the actual mechanical fabrications of columns according to the common industrial practice, and other simplifications in the heat exchanger calcualtions. In order to validate the proposed method, comparisons are made with other popular methods such as Smith-Brinkly Short-Cut Method(SB), Fenske-Underwood-Erbar-Maddox Short-Cut Method(FUEM) and Step-by-Step Method(SBSM), by means of an actual design example. Departure from the results by the Step-by-Step Method was about 10%, the latter being the method yielding the highest accuracy as well as precision. Also, in this work procedures are presented for calculations of several hardware parameters of a distillation column and of heat exchangers annexed to the column.
B형 만성 활동성 간염 환자에서 Prednisolone 단기이탈 및 Alpha Interferon 병합요법의 효과
이종선,김병호,성자원,허승식,이기천,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2
To evaluate the safety and efficacy of Pd withdrawal followed by recombinant alpha- Interferon 2b therapy. Nine patients were given a single daily subcutaneous injection of ^α-Interferon at a dose of 3 x 10 exp(6) units/day for first weeks and thrice weekly for next 15 weeks (maintenance) after pd tappered over 6 weeks. To evaluate the efficacy of therapy, we measured serum aminotransferase activities monthly during and after therapy, and also measured serm HBsAg, HBeAg and DNA probe before and after therapy. To evaluate the safety of therapy, all patients checked peripheral blood WBC, Hemoglobin, Platelet, BUN and Creatinine. The results were as follows : 1. In control group, the normalization of s-AST & ALT level, negative seroconversion of DNA probe & HBeAg were observed in 1/12(8%) & 7/10(17%), 0/10(0%) & 0/12(0%) at 6 months later, and maintained response in 1/11(9%) & 1/11(9%), 2/9(22%) & 2/11(18%) until 1 years later. 2. In treatment group, Serum AST and ALT returned to normal in 8/9 & 8/9 cases (89%) after 1 montns Tx. (mean serum AST : 33±8, ALT : 34±12 IU/ml) and maintained to normal response in 5/9(56%) & 6/9 cases(67%)after 6 months Tx. (mean s-AST : 55±43, ALT : 66±84 IU/ml), 3/9(33%) & 4/9 cases(44%) after 1 years Tx. It was statistically significant reponse except s-AST of after 1 years Tx. 3. In treatment group, s- HBeAg returned to normal in 3/9 cases(33%) after 1 months Tx., and maintained to normal response in 1/7 & 1/4 cases among follow up patients in after 6 & 12 months Tx. Serm DNA probe level were observed significantly negative seroconversion in 8/9 cases(89%) after 1 months Tx. (p<0.003), and maintained to negative response in 2/6 & 1/3 cases after 6 & 12 months Tx. 4. Serum AST, ALT, HBeAg and DNA probe were not significantly correlated with therapeutic response in relation to histologic diagnosis. 5. Fever and myalgia were noted in 9(100%) & 6(67%) cases. Headache, mild hair loss, anorexia, nausea, facial flushing & diarrhea were noted in few cases. Peripheral WBC(3cases) & platelet counts(3cases) were decreased transiently. This study shows that Pd withdrawal followed by recombinant alpha Interferon 2b therapy may be safe and effective in decrease the level of s-DNA probe, transaminase activity, loss of HBeAg and less adverse effect of clinical and hematologic examinations in patients with CAH type B. But it was necessary for study with large number of patients, more prolonged follow up duration and more strict control study.
The Distribution and Position of Fatty Acids in Glycerides Hydrolyzed from Fish Oil by Lipase
Hur, Byung Ki,Hu, Hong Bo,Yun, Hyun Shik 한국미생물 · 생명공학회 2000 Journal of microbiology and biotechnology Vol.10 No.4
In order to determine the position and the content of fatty acids attached to glycerides and the migration degree of fatty acids in the migration reaction, fish oil was hydrolyzed with lipolase-l00T which was derived from Aspergillus oryzae. The content of fatty acids in the glyceride mixture was analyzed and compared with that of fish oil. The amounts of fatty acid in a 2-position and the migration degree of the fatty acid in 2,3-DG (diglyceride) and 2-MG (monoglyceride) were carefully calculated. The results showed that approximately 95% (w/w) of DHA (docosahexaenoic acid) and 65% of EPA (eicosapentaenoic acid) were attached to the 2-position of glycerides in fish oil. Approximately 87% (w/w) of DHA and 75% of EPA remained in 2,3-DG, and 88% of DHA and 65% of EPA in 2MG were not involved in the migration reaction.
A Steady-State Combustion Modelling of Composite Solid Propellants
Hur, Byung-Ki,Kim, Chong-Bo The Korean Society of Mechanical Engineers 2001 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.15 No.4
By depicting the transfer of heat and combustion reaction to take place within thin gas layers close to the propellant surface burning in a steady-state fashion, a mathematical equation has been deduced to describe the burning rate of solid propellant as a function of initial grain temperature and chamber pressure. It has been also assumed that chemical reaction could take place in premixing-diffusing zone but were carried out mainly in the reaction-flame zone. All these phenomena taken place in each zone of combustion have been assumed to be steady-state. In the present investigation, the equation, γ=$\kappa$$.$(1/R(T(sub)i+C))(sup)n$.$exp(-E(sub)a/R(T(sub)i+C))(P/z) is being presented and it is compared with experimental data. The proposed model has been tested and evaluated vis-a-vis strand burner data for three different propellants based on CTPB, and it has been found that the deviation of the computed burning rates from the measured rates ranged up to 2%.
Hydraulic and Thermal Design of Baffled Heat Exchangers
Hur, Byung Ki,Mok, Young Il,Ahn, Tae Young 아주대학교 1982 論文集 Vol.5 No.-
障애板이 設置된 熱交換器의 製作상 불가피하게 發生되는 裂隔 즉, Shell/Tube Bundle, Tube/Baffle 사이의 間隔에 의하여 惹起되는 短絡現像(Short-Circuiting) 等 流動의 樣相을 究明하였으며, 이들의 影響을 考慮한 電力損失 및 총括傳熱係數에 대한 計算方程式을 誘導하였다. 熱交換器 內에서 流體의 流動상태에 따른 각각의 摩擦係數(Friction Factor) 및 J?? 熱傳達係數(J?? Heat Transfer factor)를 Reynolds 數와 管群의 幾何學的 排列의 兩數關係로 圖式化 함으로써 熱交換器의 流動 및 熱傳達設計에의 이용을 가능하게 하였다. 提示된 模型에 의한 計算結果를 實測値 및 現在까지 가장 잘 알려진 設計方法에 의한 計算結果와 比較 檢討하였다. 그 結果로 提示된 模型에 의한 計算値가 電力損失面에서는 5%의 誤差範圍 이내로 實測値에 接近하였으며, 총括 熱傳達係數面에서는 본 硏究의 方法과 기존해 있는 가장 좋은 設計方法에 의한 設計値 사이의 差異가 僅少하다는 것을 發見하였다.