한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

공무원 다문화역량 교육프로그램 개발연구를 위한 요구 분석

이병준,박응희,한현우 한국문화교육학회 2010 문화예술교육연구 Vol.5 No.1

노동의 세계화와 국제결혼, 다양한 종교의 유입 등 변화하고 글로벌화하는 사회환경에 따른 여러 문제들은 이제 지역차원에서의 적극적인 대응을 행정서비스에 요구하고 있다. 본 연구의 목적은 다문화사회의 진입에 따른 직접적인 행정서비스를 수행하고 있는 공무원들을 대상으로 그들의 다문화역량개발에 도움을 줄 수 있는 교육프로그램을 개발하기 위한 요구를 파악하기 위함이다. 다문화역량은 다문화학습의 과정을 거쳐 생겨난다고 알려져 있다. 특히 다문화역량의 구성요소에 관해서는 국가와 연구자별로 차이를 보이고 있는데, 미국의 경우 다문화역량은 문화적 의식, 등을 거쳐 습득되는 문화적 역량의 개념으로 이해되어지며, 독일의 경우 다문화역량은 의사소통능력, 갈등관리능력 등의 기초역량에서부터 문화 간의 차이 인정 능력에 이르기까지의 문화적 역량이 포괄된 역량으로 이해되어지고 있다. 본 연구의 결과로 나타는 현재의 공무원들의 다문화역량에 대한 의식수준은 전반적으로 평균수준이며 결핍된 역량에 대한 교육요구는 상당히 높다고 볼 수 있다. 특히 적지 않는 공무원들이 자기 자신의 변화가 우선적으로 중요하다고 답변한 것은 프로그램의 기획에 있어 시사하는 바가 적지 않다고 볼 것이다. The purpose of this study is to make basic materials of education programs helping competency development for public officials who are conducting public service directly, as the multi-cultural society has come. The variety of issues came after the changeable and globalized social environment such as globalization in labor industry, international marriage and introduction of diverse religion. Those are in need of active responses to public service. We recognize the need of education programs that fit in the multi-cultural paradigm, then it can possibly be used for building curriculum and education system of multi-cultural competency development as basic materials. We have to promote a learning culture for the proper response to the multi-cultural society. It can be helpful to enter a mature civil society when we recognize and embrace identities of minority groups through an education for public officials who directly provide the multi-cultural public service.

LC-MS/MS를 이용한 S.D. Rat 혈장 중 Arctiin 분석법 개발

송병정,채정우,백현문,권광일 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

KIOM-MA128 is a novel oriental herbal medicine which is for atopic dermatitis and asthma. The purpose of this study was to develop on analytical method of arctiin in rat plasma after oral administration of KIOM-MA128. Analyte was separated on a Atlantis dC18 reverse phase column, using gradient mobile phase (A:B = acetonitrile: 0.1% formic acid in water) at a flow rate of 0.3 mL/min. Detection was performed by electrospray positive ionization mass spectrometry using multiple reaction monitoring of the transitions of arctiin at m/z 552.4 → 372.8 and internal standard (carbamazepine) at m/z 237.0 → 194.5. The limit of quantification was 1 ng/mL for arctiin. The precisions were lower than 15% and the accuracy was between – 12.21 and 3.2%. The maximum concentration found in plasma samples was 4.1 ng/mL. The present method was successfully developed for detecting arctiin in plasma and this results would be utilized to the further study.

이탈리안 라이그래스의 성숙종자 유래 캘러스로부터 효율적인 식물체 재분화

우현숙,이상훈,이동기,김진수,원성혜,이병현 Plant molecular biology and biotechnology research 2004 Plant molecular biology and biotechnology research Vol.2004 No.-

As an initial step for future genetic manipulations to improve forage characteristics of Italian ryegrass (Lolium multiflorum Lam.), an efficient tissue culture system was established and the factors affecting plant regeneration were evaluated. MS medium containing 5 ㎎/L 2,4-D was optimal for embryogenic callus induction from mature seed and had a strong effect on successive plant regeneration. The plant regeneration frequency was observed at above 70% when embryogenic calli induced were transferred to N6 medium supplemented with 1 ㎎/L 2,4-D and 5 ㎎/L BA. Among several basic media tested, MS and M6 medium were optimal for callus induction and plant regeneration, respectively. Genotype was an important factor in plant regenerability. 'Jeanne' showed the highest regeneration frequency of 73%. A short tissue culture period and high-frequency regeneration system established in this study will be useful for molecular breeding of Italian ryegrass through genetic transformation.

영구형 항서맥 심박조율기 환자의 장기추적관찰

최현석,이무용,최영진,최성준,김효수,손대원,오병희,이명묵,박영배,최윤식,이영우,이명용 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.5

고추 1986年度 수集在來種의 裁培的 特性과 1987年度 蒐集在來種의 種果特性

金炳洙,李愚升,朴鉉圭,許宗汶,余淳南 慶北大學校 1988 論文集 Vol.46 No.-

Ten Korean local cultivars of pepper (Capsicum annuum) collected in 1986 were planted in the Kyungpook National University Experiment Farm to investigate growth characteristics. 'Punggakcho' was late in flowering, bearing large fruits, and high yielding. 'Kalmicho' was vigorous, good in fruit setting, and slightly resistant to bacterial spot but badly infected with powdery mildew. These two cultivars were the most promising materials for pepper breeding. Local cultivars collected in Younyang in Kyungpook such as 'Chilsungcho', 'Subicho', and 'Daehwacho' were poor in growth and suffered from viral complexes. As results, size and form of the original seed fruits was not reproduced but small and malformed fruits were produced. Collection of local cultivars of pepper was continued in 1987. Fruits of 14 local cultivars were collected in Youngwol in Kangwondo, Bonghwa and Munkyung in Kyungpook, Guchang in Kyungnam, and Jejudo, and their fruit characters were recorded.

암 환자의 혈장 Transforming Growth Factor-β1 농도

박병규,하우송,이시은,이수진,박순태,박찬후,전지현,장정순 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1999 Journal of biomedical laboratory sciences Vol.5 No.2

한국인의 대표적인 성인 고형 종양인 위암, 간암, 유방암과 소아 백혈병 및 2종의 소아 고형 종양 환자로부터 혈장 transforming growth factor-ß1 (TGF-ß1) 농도를 sandwich ELISA 분석법을 이용해 측정함으로써 TGF-ß1을 이 질환들에 대한 새로운 종양표지자 (tumor marker)로 사용할 수 있는지 검토하였다. 또한 연령 및 성별에 따른 혈장 TGF-ß1 농도의 정상치를 조사하였다. 신생아에서 70대까지 혈장 TGF-ß1 농도의 차이는 없었고 남녀간의 차이도 없었다. 위암 환자의 혈장TCF-ß1 농도는 16.0±6.8 ng/ml (평균 ±표준편차)로 정상 대조군의 TGF-ß1 농도 (8.3 ±5.0 ng/ml) 보다 유의하게 높았으나 간암, 유방암 환자의 혈장 TGF-ß1 농도는 대조군과 차이가 없었다. 그리고 위암 환자 16명, 간암 환자 8명, 유방암 환자 7명 중 각각 7명 (43.7%), 1명 (12.5%), 1명 (14.3%)에서만 혈장 TGF-ß1 농도가 증가되었다. 5명의 소아 백혈병 환자에서는 관해 (remission) 여부와 상관없이 혈장 TGF-ßl 농도가 모두 정상 범위에 있었으나 2명의 소아 고형암 환자에서는 종양 절제 전에는 혈장TGF-ß1 농도가 높았다가 절제 후 정상으로 떨어졌다. 결론적으로 1)정상인의 혈장 TGF-ßl 농도는 연령 및 성별에 따른 차이가 없다는 것을 알 수 있었고, 2)성인 고형암인 위암, 간암, 유방암에서는 낮은 민감도로 인해 TGF-ß1을 진단을 위한 선별 검사로 이용하기에는 부적절한 것으로 판단되었으며, 3) 정상 대조군보다 혈장 TGF-ß1 농도가 높았던 위암 환자와 종양 절제 전후로 혈장 TGF-ß1 농도가 민감하게 변했던 소아 고형 암 환자에 대해서는 향후 표본 수를 늘려 부가적인 연구를 해 야 할 것으로 사료된다. To evaluate the usefulness of transforming growth factor-ß1 (TGF-ß1)as a new tumor marker, we determined the plasma TGF-ß1 levels using sandwich ELISA assay in cancer patients. Patients with three most common adult cancers in Korea (stomach, liver and breast cancer) and children's cancers (leukemia and two kinds of solid tumor) were enrolled for the study. Furthermore, 39 individuals were subjected to age and sex-stratified plasma TGF-ß1 analysis. No statistical difference was demonstrated with respect to age or sex. The mean plasma TGF-ß1 level (16.0 ng/ml) of stomach cancer patients was significantly higher than that (8.3ng/ml) of controls. However, there was no difference among the mean plasma TGF-ß1 levels of liver, breast cancer patients and controls. Seven of 16 patients (43.7%) with stomach cancer, one of 8 (12.5%) with liver cancer, and one of 7 (14.3%) with breast cancer showed higher TGF-ß1 levels compared to controls. Plasma TGF-ß1 concentrations of five leukemic children remained in the normal range regardless of the remission state. In contrast, initial high TGF-ß1 levels from two children with solid tumors returned to normal range on surgical resection of tumors. From the above results, we could conclude that plasma TGF-ß1 levels of apparently healthy individuals seem to be rather constant irrespective of difference in age or sex, and the plasma TGF-ß1 has the limited value as a screening test for the diagnosis of aforementioned adult cancers because of its low sensitivity. Finally, additional studies need to be pursed for the large number of stomach cancer and pediatric solid tumor patients in order to reach a secure conclusion on the usefulness of plasma TGF-ß1 as a tumor marker in these patients.

철근콘크리트 장방형 전단벽의 비선형 유한요소 해석

윤현도,한민기,김선우,박완신,양일승,한병찬 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.2

The major objective of the present study is to conduct parametric study and to propose a finite element analysis(FEA) technique of the reinforced concrete rectangular shear walls using ABAQUS under constant axial and monotonic lateral load. A FEA of the reinforced concrete walls are different to aspect ratio and a detailed finite element models are created to study the post-cracked mode of failure in plastic region of the walls. The proposed models account for the effect of material inelasticity, concrete cracking, and geometric nonlinearity. The prossed FEA model is verified by Lefas's benchmark data and validated through comparisons with experiment result of reinforced concrete shear walls. Finally, the study considered various parameters and compared with ACI 318-02 to confirm accuracy of this study: aspect ratio, axial force ratio, vertical and horizontal reinforcement ratio.

PEM을 이용한 連續基礎의 支持力에 대한 信賴度 解析

吳秉炫,羅德寬,朱宰佑 순천대학교 공업기술연구소 1994 工業技術硏究所論文集 Vol.8 No.-

The reliability analysis are performed for the bearing capacity of strip foundation using the point estimate method. The measure of the safety of structure is expressed in terms of the probability of failure instead of the conventional factor of safety. The analysis of the uncertainties around input parameter which is involved soil, site and loading condition introduce a measurable uncertainty on the prediction of bearing capacity of strip foundation. Both the soil properties and loads are assumed to be probability variables, and considered correlations of each variated. And as expected, the difference in the probability of failure of bearing between beta and normal distribution seems to be insignificant for practical use but the probability of failure by the given value of the correlation of each variable is more sensitive than that of not to be considered case. If probabilistic analysis techniques are to be adopted, it will be necessary to develop probability based tolerable bearing capacity criteria.

지능형 원격 네트워크 온실

문병현,송주열,이현성,손경규,엄태환,김정우,김아름 대구대학교 정보통신연구소 2004 情報通信硏究 Vol.3 No.2

The system designed in this paper, can mark the interior state of greenhouse using sensors of temperature, humidity and illumination on greenhouse interior by greenhouse system for farm village area's agriculture automation. And, the real time monitor is possible real time monitoring by camera. Also, system that can supply water using spring cooler system and humidifier. The proposed system can sustain a designed environment of the greenhouse through rentilation fan, fluorescent light and roof door control. TCP/IP is used for the remote control of state the sensors in the client program. 본 논문에서 설계된 시스템은 농촌 지역의 농업 자동화를 위한 온실 시스템으로 온실 내부에 온도, 습도, 조도 센서를 이용한 온실 내부의 상태를 표시할 수 있으며 카메라를 이용하여 실시간 관측이 가능하다. 또한 본 시스템은 지붕 개폐, 스프링 쿨러와 가습기를 이용한 수분 공급, 환풍기, 형광등 등을 통하여 온실 내부의 환경을 유지시킬 수 있다. 모든 센서를 이용한 상태와 온실 제어를 TCP/IP를 이용한 클라이언트 프로그램에서 원격으로 관리할 수 있다.