서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

65세 이상의 노령층에서 고지혈증의 위험요인

김용배,장원기,황보영,김화성,안규동,이병국,이용진,김세훈,김승수,김승훈,김영록,김웅빈,이성수 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

..

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

Identification of a sensitive urinary biomarker, selenium-binding protein 1, for early detection of acute kidney injury

Kim, Kyeong Seok,Yang, Hun Yong,Song, Hosup,Kang, Ye Rim,Kwon, JiHoon,An, JiHye,Son, Ji Yeon,Kwack, Seung Jun,Kim, Young-Mi,Bae, Ok-Nam,Ahn, Mee-Young,Lee, Jaewon,Yoon, Sungpil,Lee, Byung μ,Kim, Hyung TAYLOR & FRANCIS 2017 Journal of Toxicology and Environmental Health Vol.80 No.9

<P>Acute kidney injury (AKI) is associated with increased mortality rate in patients but clinically available biomarkers for disease detection are currently not available. Recently, a new biomarker, selenium-binding protein 1 (SBP1), was identified for detection of nephrotoxicity using proteomic analysis. The aim of this study was to assess the sensitivity of urinary SBP1 levels as an early detection of AKI using animal models such as cisplatin or ischemia/reperfusion (I/R). Sprague-Dawley rats were injected with cisplatin (6 mg/kg, once i.p.) and sacrificed at 1, 3, or 5 days after treatment. Ischemia was achieved by bilaterally occluding both kidneys with a microvascular clamp for 45 min and verified visually by a change in tissue color. After post-reperfusion, urine samples were collected at 9, 24, and 48 hr intervals. Urinary excretion of protein-based biomarkers was measured by Western blot analysis. In cisplatin-treated rats, mild histopathologic alterations were noted at day 1 which became severe at day 3. Blood urea nitrogen (BUN) and serum creatinine (SCr) levels were significantly increased at day 3. Levels of urinary excretion of SBP1, neutrophil gelatinase-associated lipocalin (NGAL), and a tissue inhibitor of metalloproteinase-1 (TIMP-1) were markedly elevated at day 3 and 5 following drug treatment. In the vehicle-treated I/R group, serum levels of BUN and SCr and AST activity were significantly increased compared to sham. Urinary excretion of SBP1 and NGAL rose markedly following I/R. The urinary levels of SBP1, NGAL, TIMP-1, and KIM-1 proteins excreted by AKI patients and normal subjects were compared. Among these proteins, a marked rise in SBP1 was observed in urine of patients with AKI compared to normal subjects. Based upon receiver-operator curves (ROC), SBP1 displayed a higher area under the curve (AUC) scores than levels of SCr, BUN, total protein, and glucose. In particular, SBP1 protein was readily detected in small amounts of urine without purification. Data thus indicate that urinary excretion of SBP1 may be useful as a reliable biomarker for early diagnosis of AKI in patients.</P>

미소결함의 형상인식을 위한 디지털 신호처리 적용에 관한 연구

김재열,홍석주,이규태,김병현,김훈조,김양중 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.1

In this study, the classified researches the artificial and natural flaws in welding pails are performed using the pattern recognition technology. For this purpose the signal pattern recognition package including the user defined function was developed and the total procedure including the digital signal processing, feature extraction, feature selection and classifi-er selection is treated by bulk. Specially it is composed with and discussed using the statistical classifier such as the linear discriminant function the empirical Bayesian classifier. Also, the pattern recognition technology is applied to classifica-tion problem of natural flaw(i.e multiple classification problem - crack, lack of penetration, lack of fusion, porosity, and slag inclusion, the planar and volumetric flaw classification problem). According to this results, it is possible to acquire the recognition rate of 83% above even through it is different a little according to domain extracting the feature and the classifier.

학생청소년의 불안성향과 문제행동 유형간의 상관분석

김헌수,이재우,나철,김영돈,김민호,김은희,권지란,박광식,이길홍,민병근 중앙대학교 의과대학 의과학연구소 1987 中央醫大誌 Vol.12 No.4

The purpose of the present study was to examine the relationship between their problem behavioral pattern and anxious trends among Korean student adolescent. Zung's measurement of anxiety level undergone through used of the self-rating anxiety scale. the data were collected through the questionaire survey which was conducted on Dec.1, 1983. Subjects served for this atudy consisted of 1,404 syudents in Korea, randomly sampled from Korean student population by means of census method. The data were analysed by CDC-174 computer of KAIST, using SPSS pogram. Statistical methods empoyed were χ^2 test and Eta measures. the results of this study were as follows. 1. It showed that students psychological anxious trends had greatest significant correlation with adolescent student's problem brhavioral pattern, but the cardiovascular, respiratory, gastrointestional and genitourinary anxious trends has not significantly related with student's problem behavioral pattern. 2. Students group with undersocialized aggressive, undersocialized nonaggressive,undersocialized school-norm avoidant, or socialized nonaggressive behavioral patterns were less anxious, whereas those with socialized latent aggressive, socialized sexual, or socialized modellong behavioral patterns were higher anxious.

신경회로망에 의한 용접 결함 종류의 정량적인 자동인식 시스템 개발에 관한 연구

김재열,김영석,김병현,유신,김훈조,정진홍 한국공작기계학회 1997 한국생산제조학회지 Vol.6 No.1

A neural network approach has been developed to determine the depth of a surface breaking crack in a steel plate from ultrasonic backscattering data. The network is trained by the use of feedforward three-layered network together with a back-scattering algorithm for error correction. The signal used for crack insonification is a mode converted 70˚ transverse wave. A numerical analysis of back scattered field is carried out based on elastic wave theory, by the use of the boundary element method. The numerical data are calibrated by comparison with experimental data. The numerical analysis provides synthetic data for the training of the network. The training data have been calculated for cracks with specified increments of the crack depth. The performance of the network has been tested on other synthetic data and experimental data which are different form the training data.

고삼투압성 비케톤성 상태의 예후인자

안성훈,김양원,김미란,진헌철,안지영,이상래,류석용,김홍용,김성준,이병권,김경환 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Background: A hyperosmolar nonketotic state has been known to have a high mortality, and even now, despite this high mortality, only a few studies of this disease have been performed. We studied the prognostic factors for the hyperosmolar nonketotic state. Methods: We retrospectively studied the cases of 40 patients who were in a hypersomolar nonketotic state when admitted to Sanggye Paik Hospital during the 6-year Period from 1995 through 2000. We divided the hyperosmolar nonketotic patients into two groups, the complete recovery group and the incomplete recovery group, and compared the clinical features, the laboratory findings, and the precipitating factors between two groups. Results: 1) A total of 40 patients were studied: 24 in the complete recovery group and 16 patients in the incomplete recovery group. The mortality rate was 32.5%. 2) No significant statistical difference existed among the clinical features of the two groups, except for the sex(p<0.01). 3) Among the laboratory findings of both groups, analysis revealed that the effective osmolarity was significantly higher among those in the incomplete recovery group(p<0.01). Serum sodium concentration was also significantly higher among those in the incomplete recovery group(p<0.01). Serum creatinine was also significantly higher among those in the incomplete recovery group(p<0.05). Serum bicarbonate concentration, on the other hand, was significantly lower among those in that group(p<0.05).4) Infection was identified as the most common precipitating factor(62.5%). Among the precipitating factors of the two groups, there were significant statistical difference in pneumonia, UTI, and inappropriate glucose control. 5) A significant statistical difference existed among the initial level of consciousness of both groups(p<0.05). 6) The only significant independent factor responsible for prognosis of nonketotic hyperosmolar state patients was the sex. Conclusion: The sex was only significant independent prognostic factor of nonketotic hyperosmolar state patients.

청소년비행과 성격양상 및 가족역동간의 관계

김헌수,민병근,김현실 울산대학교 의과대학 1992 울산의대학술지 Vol.1 No.1

The present study was intended to explore the correlation between juvenile delinquent behavior and their character, mood state and family dynamics. Data were collected through questionnaire survey. Subjects served for this study consisted of 1,838 adolescents including 601 juvenile delinquents and 1,237 adolescent students in Korea, sampled from Korean student population and adolescent delinquent population confined in juvenile correctional institutions, using nonprobability samping method. Their age ranged between 12 and 21. The actual number of cases put into the analysis was 1,696 adolescents including 511 delinquents and 1,185 adolescent students. Data were analysed by IBM PC of Behavioral Science Center at the Korea University, using SAS program. Statistical methods employed were χ²test, simple correlation, principal component analysis, principal component regression analysis and LISREL path analysis. The results of this study were follows: 1. Inconsistent by parental child rearing patterns tended to affect delinquent behavior among delinquent adolescents. The more were paternal and maternal attitudes arbitrary, restricted, mistrusing their children and punishment-oriented, the higher occured their children's delinquent behavior. On the other hand, adolescent students were consistently rearing by their parents, their parental attitudes were democratic, flexible, trusting their children and reward-oriented. In comparison of both parents in the degree of influence on their children was revealed that paternal child rearing pattern was more influential on their children's behaviors than maternals's. 2. The psychological instability of family tended to be contributing to deliquent behaviors among deinquent adolescents. Coldness, dissatisfaction, discord, tenseness and disharmony of family paychological climate revealed significant correlation with delinquent behaviors. On the other hand, student's family stability was more comforable than delinquent family. 3. The disharmonious parent-child relationships were presented to influence on delinquent behaviors and aggressive impulsiveness. Parental rejection toward their children's opinions, lack of affection toward their children, non-self-sacrificing for their children, alienated parent-child relationship, children's disregard toward their parental authority and children's rejection of parental opinions were positively correlated to behavioral problems among delinquent adolescents, while harmonious parent-child relationships among student adolescents were maintained. 4. The whole psychological climates of delinquent's family tended to be rigid, while student's psychological climates of family flexible. 5. Delinquents were more anxious, aggressive and impulsive than student adolescents. They exhibited some learning problems such as interpersonal difficulties. their character patterns tended to be immature and weak ego functioning, while student's character patterns more mature and flexible. 6. The relative comparison of the whole psychological climates of family, anxiety trait, character pattern and social learning ability in terms of predictability revealed that character pattern variables function as the most important determinant of both aggressive impulsiveness and delinquent(aggressive) behaviors.

靑少年 犯罪類型과 韓國 家族形態間의 關係

金憲秀,閔秉根,金賢實 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3

본 연구의 목적은 한국가정의 가족형태분류, 청소년 범죄유형분류 및 범죄유형의 심각성과 가족형태간의 상관성을 규명하는데 있다. 연구대상자 선정방법은 비례층화적 표본추출법을 적용하여 1994년 9월 현재 중학교 1학년에서 고등학교 3학년까지 재학중인 학생청소년 1,283명과 소년원·분류심사원에 재소 중인 비행청소년 413명인 총 1,696명으로 하였다. 연구조사방법은 설문지법으로 수집된 자료중 불충분한 응답을 한 141명을 제외한 1,555명을 실제자료분석대상으로 하였다. 연구대상자의 연령범위는 12세에서 18세 사이였다. 본 연구에서는 수집된 자료분석과 문헌고찰을 통하여 우선 한국의 가족형태와 청소년 범죄유형을 분류분석한 후 가족형태와 범죄청소년들의 범죄유형의 심각성간의 관계를 규명하기 위하여 가족형태를 독립변인, 범죄유형의 심각성을 종속변인, 청소년의 정신사회적 스트레스요인(생활사건)과 성격적 요인을 매개변인으로 하여 범죄유형집단간의 차이를 비교·분석하였다. 자료분석은 SAS프로그램을 이용하였으며 사용된 통계방법은 요인분석, 상관계수분석법 및 부분상관계수분석법 등이었다. 연구결과는 다음과 같다. 1) 한국가정의 가족형태는 충동행동화형, 정상합의형, 구속억압형, 무질서형, 폐쇄형 및 미숙형 등의 6가지 유형으로 분류되었다. 2) 한국청소년의 범죄유형은 문헌고찰을 통하여 재산범, 강력범, 폭력범 및 특별법범 등 4가지 유형으로 분류되었다. 3) 가족원간의 불안이 고조되어 있으며 역할의 모호, 충동 및 갈등해결을 행동으로 표출시키는 충동행동화형가정에서 양육된 청소년들은 대물지향적 공격성향이 높아 기물파손, 재산파괴, 절도 등의 재산범법행위가 높은 반면에 가족원간의 불신, 비협조, 불안을 주특징으로 보이는 무질서형 가정과 부모나 주변환경에 대한 불만이 많음에도 불구하고 고민이나 갈등표현을 억제하는 폐쇄형 가족형태에서 양육된 청소년들은 대인지향적 공격성향이 높아 행패, 구타, 무기소지 등의 폭력범법행위가 많았다. 특히 폐쇄형 가족형태에서 성장한 청소년에게는 강력범법행위도 높게 나타났다. 4) 가족의 질병이나 가족싸움과 같은 가족 내 문제와 청소년개인의 성격적 특성(권위저항 성격, 극심한 기분 변화 등)이 충동행동화형 가족형태와 관련있는 반면에 충동적 행동·즉각행동·권위저항행동 등과 같은 청소년개인의 성격적 특성이 충동행동화형 가정에서 자란 청소년자녀들의 대물지향적 범죄 즉 재산범법행위의 심각성을 더해주는 것으로 나타났으나 이들 청소년의 환경적, 성격적 요인이 충동행동화형가정과 재산범의 상관성에 매개역할은 하지 않았다. 5) 가족원간의 싸움, 청소년의 진로문제 등이 폐쇄형 가족형태와 관련되어 있는 반면에, 폐쇄형 가정에서 강력범죄의 심각성에는 충동행동화형 가족형태와 재산범과의 관계에서와 같이 충동적 행동, 즉각행동, 권위저항행동 등과 같은 청소년개인의 성격적 특성이 강력범죄의 심각성과 관련되어 있었으나 청소년의 스트레스 요인·성격적 요인이 폐쇄형 가정과 강력범의 상관성에 매개역할은 하지 않았다. 6) 무질서형 가족형태와 특별히 관련된 청소년의 성격적 환경적 스트레스요인은 없었으나 무질서형 가족형태에서는 가족내문제보다 무단결석, 무단가출과 같은 청소년의 행동 및 성격적 특성이 청소년자녀의 폭력범죄의 심각성과 관련되어 있었으나 이들 청소년의 환경적, 성격적 요인이 무질서형 가정과 폭력범의 상관성에 매개역할은 하지 않았다. 7) 청소년개인의 충동적 행동, 무단결석, 무단가출과 같은 행동특징적 요인이 폐쇄형 가족형태와 관련되어 있었으며 또한 폐쇄형 가족형태에서 청소년폭력범죄의 심각성에도 무단결석이나 무단가출과 같은 요인이 관련되어 있었으나 이들 요인이 폐쇄형 가족형태와 폭력범의 상관성에 매개역할은 하지 않았다. 이와 같이 청소년의 환경적 스트레스요인 및 성격적 요인이 특정가족형태와 청소년범죄유형간의 상관성에 매개변인으로 작용하고 있지 않음을 알 수 있었다. 그러나 이상에서 제시한 바와 같이 청소년 비행 및 범죄행동이 부모의 양육태도, 가족원간의 관계와 같은 가정환경적 요인과 청소년개안의 성격적 요인의 상호작용에서 비롯되는 반면에 청소년범죄의 심각성에는 가정환경적 요인보다 충동성, 권위저항성 등과 같은 개인의 성격적 요인이 보다 크게 작용함을 알 수 있었다. Objects : The purpose of this study was to classify the current family type and juvenile criminal patterns in Korea, and then examine the correlation between juvenile criminal pattern and family type, environmental stress and personality variables of the adolescents. Methods : The data were collected through the questionnaire survey. Subjects served for this study consisted of 1,696 adolescents(1,283 student adolescents : 413 delinquent adolescents) in Korea, sampled from Korean student population and adolescent delinquent population confined in juvenile correctional institutions, using the proportional stratified sampling method. Their age range was between 12 and 18. The actual number of cases put into the analyses was 1,555 including 1,202 student adolescents and 353 delinquent adolescents. Data were analysed by SAS program. Statistical methods employed were, factor analysis, correlation analysis and partial correlation analysis etc. Results : 1) Analysis of adolescents reports of family dynamic environment yielded 6 family types including impulsive family type, well-functioning family type, constricted family type, chaotic family type, closed family type and immature family type in the order of their explanatory variate. In a word, impulsive family type is operationalized as involving impulsiveness of family members, acting out, emotional explosion, resistance toward authoritative figure including their parents and adults, blurred role boundaries of family member, constricted family type as involving restricted parenting to children, punishment-oriented, autocratic father and submissive mother, chaotic family type as involving parental breakup, selfish parent, economic problem, mistrust and neglect among family members, closed family type as involving social isolation, mistrust to surrounding world, parental indifference and neglect toward their children, disobedience and parental evasion of conflict, immature family type as involving a lack of independency of family members, indecisiveness, pathological bonding of family members including winning of spouse's favour and maternal dominance-paternal ineffectiveness, projection and conjugal competition. Whereas the construct defining well-functioning family type is conceptualized as involving childrens' respect toward parent, democratic and flexible parental attitude toward their children, cooperation and trust among family members and harmonious parent-child relationship etc. 2) Through the literature review, the authors arbitrarily classified the 4 juvenile criminal patterns as follows ; crimes against property, aggressive crimes, assault crimes and violation of criminal special law. 3) The hypothesis 1 is that there will be significant correlation between family type and the severity of juvenile criminal patterns. Through the correlation analysis, this hypothesis was supported. To put it concretely, of the correlation between the severity of juvenile criminal pattern and family type in Korea, impulsive family type significantly correlated with the severity of object-oriented crime, that is, damage to property, robbery, burglary and so no, whereas chaotic family type and closed family type significantly correlated with the severity of person-oriented crime(crimes against person), that is violent act, physical assault and aggressive crime and so on. 4) The hypothesis 2 is that there will be significant correlation between family type, severity of juvenile criminal behavior and environmental and personality variables of adolescent. In this paper, environmental variables of adolescent were measured by death of parent, trouble between parent, divorce of parent, chronic disease of family member, parental overdrinking and dissipation, severe conflict with parent, trouble with lover and problem in a course of one's life. And personality variables of adolescent were measured by trouble among family member, habitual alcohol drinking, emotional instability, impulsiveness, truancy, runaway, resistance toward authoritative figure and intolerance. From this finding using the partial correlation analysis, it revealed that the environmental and personality variables of adolescent such as chronic disease of family member, trouble with lover, trouble among family member, emotional instability and resistance toward authoritative figure were significantly correlated with the impulsive family type and the personality variables of adolescent such as impulsiveness, intolerance and resistance toward authoritative figure had statistically significant correlation with the severity of damage of property in the impulsive family type. And the environmental stress and personality variables of adolescent such as problem in a course of one's life and trouble among family member were significantly correlated with the closed family type and the personality variables of adolescent such as intolerance, impulsiveness and resistance toward authoritative figure were significantly correlated with the severity of aggressive crimes in the closed family type. However, the authors did not find any environmental stress and personality variables of adolescent that were significantly correlated with the chaotic family type, whereas the problem behavior of adolescents such as truancy and runaway was significantly correlated with the severity of assault crimes in the chaotic family type. Finally, the authors suggest that personality variables of adolescent such as impulsiveness, truancy and runaway were significantly correlated with the closed family type, also truancy and runaway were significantly correlated with the severity of assault crimes in the closed family type. 5) The hypothesis 3 is that the family environmental stress and personality variables of adolescent will serve as mediating variables in the correlation between family type and juvenile criminal pattern. Environmental stress and personality variables of adolescent such as death of mother and/or father, parental divorce, disharmonious parent-child relationship, chronic disease of family member, emotional instability, impulsiveness and resistance toward authoritative figure were not play as mediating variables in the correlation between family type and juvenile criminal pattern in this study through the hypothesis testing. Accordingly this hypothesis was rejected. Conclusion : The various family type including impulsive, closed and chaotic type in Korea tended to exert significant influence on the severity of juvenile crimes such as crimes against property, aggressive crimes and assault crimes. While environmental stress and personality variables of adolescent had direct effect upon juvenile criminal patterns and severity of juvenile criminal act, they did not play a mediating role in the processing of serious degree of criminal manifestation influenced by family types.