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( Bernardino Roca ),( Raquel Monferrer ),( Jose A Ferrero ),( Manuel Roca ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Objective: To find factors associated with increased homocysteine serum level in HIV-infected patients. Methods: Cross-sectional study, carried out as a supplementary task to the usual follow- up of HIV-infected patients. The possible association of increased homocysteine serum level with blood analyses results was assessed with a multiple linear regression analysis. Results: A total of 145 patients were included. Creatinine was higher than normal in 7 patients (5 %), prothrombin time was higher than normal in 36 patients (25 %), and a monoclonal gammopathy was detected in 2 patients (1 %). An association was found between high homocysteine serum level and the following variables: high creatinine (P < 0.001), low folic acid (P < 0.001), and low prothrombin time (P = 0.007). Conclusion: An associations was found between high homocysteine serum level and low prothrombin time.
( Manuel Roca ),( M Daniela Diaz ),( M Alexandra Mendoza ),( Bernardino Roca ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Objectives: Stress and other causes can infl uence blood pressure levels and may limit the usefulness of its measurement in the offi ce, but knowledge in this fi eld is limited. We aim to determine the impact on and blood pressure of the state of anxiety that HIV-infected patients experience when they are about to be informed of immunologic and virologic tests and other blood analysis results in clinical visits. Methods: In a cohort of HIV-infected patients, we measured blood pressure of every subject twice: at the beginning of visits just before we reported them lymphocyte CD4 cell count, HIV-viral load and other blood analysis results, and about ten minutes afterwards at the end of visits. We compared results of both determinations, and searched for factors associated with differences between both determinations, when present. Results: We included 152 patients, the median of age was 45 years (interquartile range: 39-50), 101 (66 %) were male, 24 (16 %) had been diagnosed of hypertension previously, 28 (18 %) had been diagnosed of diabetes, 25 (16 %) had been diagnosed of dyslipidemia, and 120 (79 %) were smokers; 142 (93 %) were taking antiretroviral medication. Table shows results at the beginning and at the end of visits (sBP and dBP = systolic and diastolic blood pressure, measured in mmHg). An association was found between lower sBP at the end of the visit compared to blood pressure at the beginning of the visit and the following variables: younger age (P = 0.018) and female gender (P = 0.008). Conclusion: sBP at the end of the visit is commonly lower than sBP at the beginning of the visit, especially in young women.