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이해철,김동원,권건영,이장철,손은익,임만빈,김인홍 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.9
The clinical and pathological features were analyzed for 11 cases with intracranial ependymoma treated surgically at the Keimyung University Dongsan Medical Center during the years 1987 to 1992. Tumor histology was reviewed individually and grouped into three categories(Cate-gories I to HI) according to the pathologic grade used by Nazar, et a16'. The correlation between the pathologic grade and prognosis after surgery was investigated. There were 2 cases(18%6) with category I histology, 5(45%) with category II histology, and 4(36%) with category 111 histology. The high recurrent rate. short recurrent interval, high rate of cerebrospinal fluid seeding and poor outcome were noted in patients with category IlI histology. The authors also investigated the recurrent interval according to the degree of tumor resection. The mean recurrent interval after surgery was 12 months in cases of subtotal resection and 33 months in a case of total resection. Tumors resected subtotally showed response to radiation and chemotherapy. In conclusion, the pathologic grade and the degree of tumor resection were regarded as important prognostic factors after surgery. Aggressive surgery with chemotherapy or radiotherapy were required in the management of intracranial ependymoma.
고차 통계해석을 이용한 결함이 있는 베어링에서 음향-진동 신호의 해석
이해철,차경옥 明知大學校 産業技術硏究所 2000 産業技術硏究所論文集 Vol.19 No.-
This paper present a study on the application of sound pressure and vibration signals to detect the presence of defects in a rolling element bearing using a statistical analysis method. The well established statistical parameters such as the crest factor and the distribution of moments including kurtosis and skewless are utilized in this study. In addition, other statistical parameters derived from the beta distribution function are also used. A comparison study on the performance of the different types of parameter used is also performed. The conditions, the statistical method can be used to identify the different types of defect present in the bearing. In addition, the results also reveal that there is no significant advantages in using the beta function parameters when compared to using kurtosis and the crest factor for detecting and identifying defects in rolling element bearings from both sound and vibration signals.
이해철,차경옥 明知大學校 産業技術硏究所 2000 産業技術硏究所論文集 Vol.19 No.-
Setting the channel-switching phase of automobile control mufflers in low-speed region is effective measures to improve low-speed torque. A muffler sensing exhaust-gas pressure has been developed to solve this problem. This muffler reduces exhaust noise in a pair of tailpipes by generating interference through a reverse-phasing process. This reduces exhaust noise makes it possible to set the muffler's channel-switching phase in the low-speed region.
이해철,김동원,최인장,이장철,손은익,임만빈,김인홍 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.8
신경상피 뇌종양 12례(양성 성상세포종 5례, 악성 성상세포종 2례, 수아세포종 1례, 핍지신경교종 1례, 상의세포종 1례, 맥락총 유두종 1례)를 대상으로 염색체 7, 17 및 22번에 각각 좌위한 EGRR, P^(53) 및 bcr 유전자의 변화를 찾기위해 Southern blot 분석을 시행하였다. 결과에서 EGFR 유전자의 이형접합체 소실은 2례의 수아세포종 그리고 재배열은 1례의 상의세포종에서 검색되었고, P^(53) 유전자의 이형접합체 소실은 1례의 맥락총 유두종과 1례의 양성 성상세포종에서, 재배열은 1례의 핍지신경교종에서 발견되었으며 bcr 유전자의 이형접합체 소실은 2례의 수아세포종과 2례의 양성 성상세포종에서 그리고 재배열은 2례의 악성 성상세포증에서 관찰되었다. 위의 결과로 신경상피 뇌종양의 암화과정이나 발달에 염색체 7, 17 및 22번내의 특이한 유전자 변화가 관여하는 것으로 사료되었다. Cancer may be a disease of genes, arising from genetic damage of diverse sorts-recessive and dominant mutations, large rearrangement of DNA and gene translocation on chromosomes, all leading to distorsions of either the expression or biochemical function of genes. The search for these genetic damage in neoplastic cells now is the most important in cancer research. It has been found that the cancer relevant genes were located on the specific regions of chromosomes. To determine whether epidermal p w t h factor receptor(EGFR), PS3 and bcr genes located in chromosomes 7, 17 and 22 are altered, we examined 12 neuroepithelial tumor with Southern blot analydfive low grade astrocytoma, two high grade astrocytoma, two medulloblastoma, one oligodendroglioma, one ependymoma, one choroid plexus papilloma). The loss of heterozygosity(L0H) of EGFR gene was detected in two cases of medulloblastoma. The rearrangement of EGFR gene was detected in a case of ependymoma The LOH of Pa gene was found in a case of choroid plexus papilloma and low grade astrocytoma The rearrangement of P53 gene was found in a case of oligodendroglioma. The M H of bcr gene was observed in two cases of medulloblastoma and low grade astrocytoma The rearrangement of bcr gene was observed in two cam of high grade astrocytoma. These results suggested that tumorigenesis and tumor development in the neuroepithelial tumor may involve specific gene changes in chromosomes 7, 17 and 22.
디스크 브레이크의 마찰면에서 발생되는 스퀼소음에 관한 실험적 연구
이해철,이원평,차경옥 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-
There are various noises generated by friction. Among the rest, eliminating squeal noise generated during braking is an important task for the improvement of vehicle passengers' comfort. The parameters affecting brake squeal noise are the material properties of the braking pad, the dynamic properties of the brake parts and the dimensions of the brake assembly etc. Also, the squeal noise changes its inherent form with the normal load and sliding speed. In this study, the characteristics of brake squeal noise generated by friction is analyzed experimentally. Thе experiment focused on the analysis of friction self-excited vibration and squeal noise level. Friction self-excited vibration is caused by the dry friсtiоn between pads and rotor, and occurs as a function of their relative sliding speeds. And Friction self-excited vibration is raised the brake squeal noise.
냉시동시 촉매변환기 위치에 따른 배기 배출가스 특성에 관한 실험적 연구
이해철,차경옥 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-
In order to meet the stringent emission regulations and to protect our environment, many researches have been carried out to reduce exhaust emissions from automobiles. Among these, the close-coupled catalytic converter (CCC) shortens the activation time during the warm-up period by placing it as close as possible by the exhaust manifold. This study is an experimental study on the characteristics of emission by changing catalytic converter position for cold-start. The measurements are done a changing of the distance between exhaust manifold and catalytic converter. It measured temperature of exhaust manifold, before and after catalytic converter at each position of experimental condition. and measured the characteristics of emission which is HC. CO. CO₂and lambda at each position of experimental condition.
[진동·소음부문] 자동차 배기계의 능동형 제어 머플러 개발에 관한 실험적 고찰
이해철(Haechul Lee),차경옥(Kyungok Cha) 한국자동차공학회 2000 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
This study is on the development of a new muffler composed of a valve system using an elasticity of spring. The valve system using the elasticity of spring is set along the exhaust-gas flow and designed to work itself alone the driving condition of a engine. By that reason, the engine capacity is so enlarged that a muffler with controller sensing exhaust-gas pressure is able to be satisfied to noise reduction and power enlargement more than conventional muffler. The purpose of this study is to develope the new muffler which has more noise reduction and power enlargement than conventional muffler and electric-control muffler.
CAD/CAM/CAE/PDM 시스템을 이용한 F-125차량의 개발 (1) -제품 기획 및 PDM 시스템 구축 -
이해철(Hae Chul Lee),이상헌(Sang Hun Lee) 한국자동차공학회 2003 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
This paper describes the process of product planning for a F-125 machine, which is an on-road racing car equiped with an 125cc motorcycle engine. To determine the product specification, our former machines, competitive machines, regulations of the AARK F-125 Grand Prix were investigated, and requests of racers were collected and reflected. In the early design stage, an ergonomics approach was introduced for design of a cockpit. A driver was measured and modeled using the human module of CATIA V.5. This manequine model was used to analyze driver's view range, size of seat, positions of steering wheel and pedals. In addition, a PDM system was established on the basis of TeamPDM, and used for management of product data generated mainly using CATIA V.5. Introduction of a PDM system facilitated sharing product and design information systematically between product developers.