흰쥐에서 운동부하기간의 차이에 따른 체내 저장 Glycogen 과 혈중 유리지방산의 변화양상

이영만,김종연,이석강 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.2

인쇄회로기판 제조 공정에서 위험성평가와 안전조치 적용 사례 연구

이영만,이인석 한국안전학회 2022 한국안전학회지 Vol.37 No.4

Printed circuit boards (PCBs) are a basic component in the electronics industry and are widely used in nearly all electronic products, such as mobile phones, tablet computers, and digital cameras, as well as in electric equipment. PCB manufacturing involves the use of many chemicals and chemical processes and therefore has more risks than other manufacturing sectors. This study aims to identify the causes of possible accidents during PCB manufacturing through risk assessment, develop and implement safety measures, and evaluate the effectiveness of these measures. Note that the safety measures developed to mitigate the risks of a certain process were also implemented for other similar processes. The risk assessments conducted over seven years, from 2015 to 2021, at a PCB manufacturing company identified 361 hazardous processes. Between 2016 and 2019, 41–56 hazardous processes were identified per year; such processes decreased to fewer than 20 per year after 2020. Application of the risk assessment results to the improvement of the hazardous processes with the similar characteristics seems to be effective in decreasing the risks. Equipment-related factors such as lack of appropriate maintenance, low work standards, and defective protection devices were responsible for 59.8% of all possible accidents. Because PCB manufacturing involves many chemicals, skin contact with hazardous substances, electric shock, fire, and explosion were the most common types of possible accidents (81.7%). In total, 505 safety measures were implemented, including 157 related to purchase and improvement of equipment and devices for safety (31.1%), 147 related to the installation/modification of fire prevention facilities (29.1%), and 69 related to the use of standard electrical appliances (13.7%). Risk assessment conducted after implementing the safety measures showed that these measures significantly decreased risk; 247 processes (68.4%) had a risk level of 3, corresponding to “very low,” and 114 processes (31.6%) showed a risk level of 4, corresponding to “low.” In particular, risk assessment of 104 processes with risk scores of 12 and 10 other processes with risk score of 16 showed that the risk decreased to 4 after implementing the safety measures. Thus, implementing these measures in similar manufacturing sectors that involve chemical processes can mitigate risk.

3. 배의 株間과 株內의 果実特性 変異

李榮萬,金暉千,洪庚憙,金政培 한국원예학회 1984 한국원예학회 학술발표요지 Vol.2 No.1

파프리카 농가의 GAP 관리기준 이행에 관한 조사연구

이영만,박중춘,황갑춘 경상대학교 농업생명과학연구원 2006 농업생명과학연구 Vol.40 No.4

중다지능이론과 초등학교 통합 단원 구성

이영만 한국초등교육학회 1997 초등교육연구 Vol.11 No.1

이 연구에서는 인간의 지능을 실생활과 관련된 일곱 가지 요소들로 구성되며, 사회문화적으로 상대적인 개념으로 정의하는 Gardner의 중다지능이론과 그의 이론이 통합 단원의 구성에 활용될 수 있는 가능성을 살펴보았다. 그의 이론은 인간의 지능관을 확대시켜을 뿐만 아니라, 개인 중심의 학교라는 새로운 학교관을 제시함으로써 기존 학교 교육의 개선까지 포함해서 다루는 광범위한 이론이다. 또 그의 이론은 여러 교과의 가치에 대해 다시 생각하게 하며, 통합 교과의 필요성을 뒷받침해준다. 그리고 중다지능들은 초등학교 통합 단원 구성을 위한 한 방법으로 활용될 수 있음을 살펴보았다. This study was to review Gardner's theory of Multiple Intelligence's(MI) and to see whether Gardner's theory of MI could be applied to the construction of the integrated unit for elementary school students. First, through the review of literatures I came to the conclusion that Gardner's theory of MI extended the traditional viewpoints about human intelligences, 'g', to the 7 intelligences which were very close to the real life and changed the concept of human intelligence from the general ability through all the culture to the diverse abilities according each culture. Also, he provided a new images for the school, this school, the individual-centered school, will be an alternative school for the traditional uniform school, Second, Gardner's theory of MI suggested the new viewpoints about all of the subject-matters taugh in elementary school. That is, as all kinds of the subject-matters in the school have a peculiar contribution effect for the education of the whole person, all of the subject-matters should be appreciated when constructing the integrated units or subject-matters. Third, Gardner's theory of Multiple Intelligences could be used as one of the methods for the construction or reconstruction of the integrated units or subject-matters. Especially, when we admitt one of the problems in the integrated subject-matter used in Korean elementary school is the absence of the appropriate criterion for the integration, his theory of MI will be a very valuable method for the integration of the seperated subject-matters. Finally, I suggested the needs for future research, including the very educational implications and how we can apply his theory to the entire reconstruction of the our school.

일측폐장절제가 잔류폐, 간 및 신장의 대상성 증식과 혈청전기영동상에 미치는 영향

이영만,이석강,주영은,Lee, Young-Man,Lee, Suck-Kang,Choo, Young-Eun 대한생리학회 1983 대한생리학회지 Vol.17 No.2

In order to clarify the effect of the unilateral pneumonectomy on the compensatory growth of the residual lung, liver and kidney, and serum electrophoresis pattern, right lung pneumonectomy was performed on rabbits under general anesthesia with pentobarbital sodium. On the fifth day after the surgery, the weight of the residual lung, liver and bilateral kidneys was measured and organ weight-body weight ratio was calculated. And in an attempt to know whether the cells in the liver and the kidney were proliferated by unilateral pneumonectomy, DNA content was determined. The quantity(g/100 ml) of serum protein was determined also and serum electrophoresis was performed on cellulose acetate membrane. The results obtained are summarized as following. The weight of the residual lung and lung weight-body weight ratio was significantly increased respectively. The weight of the liver and organ weight-body weight ratio were not changed but the DNA content of the liver and kidney tissue increased significantly, illustrating that unilateral pneumonectomy caused cellular hyperplasia in the liver and in the kidney as well as in the residual lung. The quantity(g/100 ml) of serum protein was significantly increased and in the analysis of the electrophoregram, there was significant difference between the normal and pneumonectomy group. Taken together, these results indicate that unilateral pneumonectomy caused the compensatory hyperplasia of the liver, the kidney and the residual lung as well as the change of electro-phoretic pattern. And it also suggests that a humoral factor, which proliferates the cells in the residual lung, the liver and the kidney, existed in the pneumonectomized rabbits.

꿀벌의 화분수량은 어떻게 조절되는가?

이영만 한국양봉협회 2001 양봉협회보 Vol.250 No.-

Betamethasone이 일측폐장절제 가토폐장의 압력-용적곡선에 미치는 영향

이영만,이석강,Lee, Young-Man,Lee, Suck-Kang 대한생리학회 1983 대한생리학회지 Vol.17 No.1

steroid가 폐절제에 의한 대상성증식기의 폐장의 압력-용적곡선에 어떤 영양을 미칠 것인가를 알아보기 위해 실시한 본 실험의 결과를 요약하면 폐절제군은 대조군에 비해 폐용압률이 증가하였고 폐절제후 반대측폐장의 무게는 대조군에 비해 폐절제군이 유의하게 증가하였고 폐절제후 betamethasone을 투여한 군에 있어서는 대조군에 비해서는 증가하였으나 폐절제군보다는 적게 증가하였다. 또한 이러한 결과들은 betamethasone에 의해 폐포표면활성물질의 분비가 증가하였거나 혹은 betamethasone이 폐장실질의 결합조직의 단백대사에 영향을 미쳐 elastic recoil force가 감소하여 생긴 결과라고 생각된다. In order to clarify the effect of steroid on the pulmonary pressure-volume curve in the pneumonectomized rabbit, the right side pneumonectomy was performed under general anesthesia with pentobarbital sodium and the remaining lung was excised on the fifth day after surgery. The intrapulmonic pressure in the excised left lung was measured at 20, 25, and 30 ml lung volume during inflation and deflation period. In the steroid treated group, the intrapulmonic pressure at 20, 25, and 30 ml lung volume during inflation was significantly decreased compared with intrapulmonic pressure of the control group. But in the pneumonectomy group the decreasing tendency of the pressure was observed. During deflation, the intrapulmonic pressure at 25 ml and 20 ml was not significantly different from the control group in pneumonectomy and steroid treated pneumonectomy group. And the lung weight was measured in each experimental group and also the lung weightbody weight ratio(L/B) was calculated. The lung weight was significantly increased in both pneumonectomy and steroid treated pneumonectomy group. Calculated L/B was increased significantly in both group. Above results suggest that steroid increases the secretion of pulmonary surfactant or affects the catabolic effect on protein metabolism of connective tissue in lung parenchyma.

측두두정근막 피판을 이용한 Frey 증후군의 예방

박은수,양순재,김용배,박종섭,이영만 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.3

Frey's syndrome is a fairly common sequelae of surgery, trauma, and inflammation of the parotid gland. Some patients with Frey's syndrome may be socially compromised by their gustatory sweating and flushing. In the past three decades, a variety of surgical and pharmacological methods have been unsuccessful in alleviating these symptoms. And since misdirection of auriculotemporal secretomotor nerve fibers has been found to play an important role in the development of the syndrome, a study was initiated to attempt mechanical interference with regenerating nerve fibers. Therefore, the recent trend in management of Frey's syndrome has been the use of prophylactic procedures performed at the time of parotidectomy to prevent its symptoms postoperatively. An additional benefit of this approach is prevention of the typical cheek contour deformity after parotidectomy. We reviewed our experience with interposition of a vascularized temporoparietal fascial flap between the parotid bed and overlying skin immediately after complete superficial parotidectomies to prevent Frey's syndrome and hollow countour defects. The result of seven consecutive attempts revealed it to be an effective technique, achieving both goals in all patients with minimal morbidity.

A Study on the Mechanism of Immunomodulating Effects of Moxifloxacin in Oleic Acid-Induced Acute Lung Injury

이영만 대한결핵및호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.2

Background: It was hypothesized that the immunomodulating effects of moxifloxacin contribute to ameliorate oleic acid (OA)-induced acute lung injury (ALI) by suppression of cytosolic phospholipase A2 (cPLA2). This was based on observations from experiments on rats associated with neutrophilic respiratory burst, cPLA2 activity, and expressions of cPLA2, TNFα, and COX-II in the lung. Methods: ALI was induced by intravenous injection of OA in male Sprague-Dawley rats. Five hours after OA injection, protein content in bronchoalveolar lavage (BAL), lung myeloperoxidase (MPO) activity, and numbers of BAL neutrophils were measured. As an index of oxidative stress-induced lung injury, the content of malondialdehyde (MDA) in lung tissues was also determined. Lung histology, immunohistochemistry and determination of activity of cPLA2 in lung tissues were carried out. In addition, Western blotting of TNFα and COX-II in lung tissues was performed. Results: The accumulation of neutrophils in the lungs was observed after OA injection. BAL protein was increased along with neutrophilic infiltration and migration by OA. Moxifloxacin decreased all of these parameters of ALI and ameliorated ALI histologically. The increased malondialdehyde (MDA) in the lung by OA was also decreased by moxifloxacin. Moxifloxacin not only suppressed cPLA2 expression in the lungs and neutrophils but also decreased cPLA2 activity in lung tissues of rats given OA. The enhanced expressions of TNFα and COX-2 in the lung tissues of rats given OA were also suppressed by moxifloxacin. Conclusion: Moxifloxacin inhibited cPLA2 and down-regulated TNFα and COX-2 in the lungs of rats given OA, which resulted in the attenuation of inflammatory lung injury.