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유대열,이경광 中央大學校 遺傳工學硏究所 1993 遺傳工學硏究論集 Vol.6 No.1
In 1980's transgenic animals expressing growth hormone genes derived from various species were developed to improved growth of livestocks or feed efficiency. But they resulted in many side effects because the constitutive and over expression of the genes affected the endocrine system. To solve these problems, other approaches using peptides related with muscle differentiation were tried but it has so far been unsuccessful. Recently, transgenic technology has been applied to develop livestocks which secrete large amounts of foreign proteins into mammary glands. Animal bioreactor is one of the most promising approaches applicable to industry. Although some transgenic animals show side effects like lactational shutdown, the animal bioreactor system is hopeful if we develop efficient expression vectors and get the basic information for the item to be produced. Basic knowledge and various technologies, including gene cloning, recombinant DNA, in vitro cell culture micromanupulation of embryos, cryopreservation, embryo transfer, breeding of animals, should be put together on line to improve the productivity of transgenic animals.
이경광,유대열 한국미생물학회 1993 微生物과 産業 Vol.19 No.1
이 논문은 형질전환 동.식물 이용기술 연구의 필요성, 연구과제의 현황, 연구동향 그리고 끝으로 연구전망 및 건의사항에 대해 기술하였다.