전신화상 후 발생된 내인성 안내염

홍지원(Ji Won Hong),노인호(In Ho Roh),배선량(Sun Ryang Bae) 대한검안학회 2007 Annals of optometry and contact lens Vol.6 No.1

목적: 내인성 안내염은 전신 감염 시 미생물이 혈행성으로 혈액 망막장벽을 넘어 안조직에 도달하여 발생하는 염증질환으로 전체 안내염의 2∼15%를 차지하는 드문 질환이다. 저자들은 전신화상 후 여러 종류의 균주에 의해 발생안 내인성 안내염 환자를 경험하였기에 이를 보고하고자 한다. 대상과 방법: 건강하던 47세 여자 환자가 열탕에 의해 전신에 30%의 3도화상으로 화상전문병원에서 부분식피술로 치료받던 중, 시력저하로 타병원 안과에서 포도막염 진단하에 스테로이드 치료를 시작하였으나 증세호전이 없어 본원으로 전원되었고, 백내장과 유리체혼탁을 치료하기 위해 초음파유화 술, 인공수정체 삽입술 및 유리체절제술을 시행하였다. 결과: 유리체 혼탁에 대해 배양검사를 한 결과 우안에서는 Candida tropicalis, 좌안에서는 Candida tropicalis와 함께 Pseudomonas putida와 Enterobacter cloacea가 검출되어 amphotericin B를 유리체강 내로 주사하였으며, 전신적인 fluconazole과 imipenem을 사용하여 치료하였으나, 최종 시력은 양안 모두에서 무광각으로 예후가 좋지 않았다. Purpose: To report a case of endophthalmitis with multiple organisms developed in a patient who was recently injured by burn. Methods: A 47-year-old woman visited with complaints of decreased binocular visual acuity 12 weeks after third degree burn injury to 30% of body surface. In other hospital, she was diagnosed as uveitis and treated with steroid. After 8 weeks later, the symptoms were not improved and she was refered to our hospital. Ocular examinations showed complicated cataract and vitreous opacities. Cataract surgery and pars plana vitrectomy were carried out and samples of the vitreous aspirate were sent for microbiological studies. Results: The culture of the vitreous of right eye showed Candida tropicalis and the culture of the vitreous of left eye showed Candida tropicalis, Pseudomonas putida and Enterobacter cloacea. She was treated with amphotericin B intravitreously and fluconazole and imipenem B intravenously, but the final visual acuity was no light perception.

PI [ Personal Identity ]의 구성요소와 사례를 통한 프로세스 연구

홍지원(Hong Ji-Won) 한국디자인학회 2009 한국디자인학회 학술발표대회 논문집 Vol.2009 No.5

디지털 환경하에서 이미지 전략 방안

홍지원(Ji Won Hong) 한국디자인학회 1999 디자인학연구 Vol.- No.33

효율적인 계층적 클러스터링 방안

홍지원 ( Ji-won Hong ),김상욱 ( Sang-wook Kim ) 한국정보처리학회 2010 한국정보처리학회 학술대회논문집 Vol.17 No.2

본 논문에서는 계층적 클러스터링의 확장성(scalability)을 향상시키기 위한 방안으로 새로운 초기 클러스터링 기법을 제안한다. 본 논문에서는 k-NN 그래프를 구축하여 초기 클러스터의 중심이 될 객체를 찾고, 이 객체를 중심으로 유사한 다른 객체들을 초기 클러스터에 포함시키는 방법을 제안하고, 실험을 통해 제안하는 방법의 성능 개선 효과를 규명하였다.

일러스트에 표현에 있어서 PI와 창조적 아이디어 발상에 관한 연구

홍지원(Hong Ji Won) 한국일러스아트학회 1998 일러스트레이션학 연구 Vol.3 No.-

The most important device in illustration is creative ideas. Ideas stem from our inner emotions, our experience, our knowledge and the environment around us. A Personal Identity Program(PIP) is one way to help explore inner thoughts in order to fully exploit a person`s potential creative ability. PIP consists of Mind Identity(MI) and Behavior Identity(BI). These allow a person to express ideas through Visual Identity(VI). Ideas can be expressed using these methods: 1. Poetry, music, painting, photos other physical car verbal art forms. 2. Imitation can be used to create basic work. 3. See, Feel, Think(SFT). Attentively scrutinizing, absorbing, and contemplating our environment and ourselves. Through, these methods and by using illustration as a tool, gable a pea their own special characteristics and imaginative, high quality work can be produced.

비판적 교육학 관점에서 바라본 2015 교육과정 초등학교 5·6학년 영어 교과서 분석

홍지원 ( Ji Won Hong ),마지현 ( Jee Hyun Ma ) 21세기영어영문학회 2021 영어영문학21 Vol.34 No.4

This study explores the reading texts and culture sections of 5th and 6th grade elementary English textbooks from a critical pedagogy perspective. This study adopted qualitative approaches to discover and critically present parts where any potential discrimination was found and to suggest more ideal ways to present countries, races, and cultures in textbooks. Specifically, this study investigated how different countries and races in the reading passages and culture sections are presented and examined prejudices and biases that the textbooks allusively produced. The results displayed that certain countries were presented in a decontextualized way with shallow information and described as economically and politically lagging while only positive aspects of some counties were magnified. As for racial analysis, it was shown that white characters were mainly presented at the center of illustrations. Furthermore, the characters who solved challenging issues over the world and received positive evaluations were also represented mainly by the white race. Much of the cultural content was presented simply without sufficient background information, and many of the current political power dynamics were revealed.

Characterization of a Korean Domestic Cyanobacterium Limnothrix sp. KNUA012 for Biofuel Feedstock

Ji Won Hong(홍지원),Seung-Woo Jo(조승우),Oh Hong Kim(김오홍),Mi Rang Jeong(정미랑),Hyeon Kim(김현),Kyung Mok Park(박경목),Kyoung In Lee(이경인),Ho-Sung Yoon(윤호성) 한국생명과학회 2016 생명과학회지 Vol.26 No.4

사상체 토착 남세균을 경상남도 합천군 합천호의 수화시료로부터 무균적으로 분리하였으며, 형태적 · 분자적 동정 결과 림노트릭스 속에 속하는 것으로 밝혀졌다. 따라서, 본 남세균 균주는 림노트릭스 속 KNUA012 균주로 명명하였으며, 분리균주의 최적생장 온도는 섭씨 25도였다. 지질성분 분석 결과, 에스테르 교환반응을 거치지 않고 직접 연료로 사용할 수 있는 펜타데칸(C15H32)과 헵타데칸(C17H36)과 같은 알칸들이 본 균주에 의해 광독립 영양적으로 생합성 된다는 것이 밝혀졌다. 또한 알칸 생합성에 관여하는 유전자들이 본 남세균 내에 존재하는 것을 발견하였다. 일반적인 미세조류 바이오디젤 구성성분으로 알려진 미리스트올레산(C14:1), 팔미트산(C16:0) 및 팔미톨레산(C16:1) 역시 KNUA012 균주에 의해 주요 지방산 성분으로서 생산되는 것으로 확인되었다. 근사분석 결과 KNUA012 균주의 휘발성물질 함량은 86.0%였으며, 원소분석 결과 고위발열량은 19.8 MJ kg<SUP>-1</SUP>으로 나타났다. 또한, 본 분리균주는 고부가가치 항산화물질로 알려져 있는 피코시아닌을 광독립영양적으로 21.4 mg g<SUP>-1</SUP>의 농도로 생산할 수 있는 것을 확인하였다. 따라서, 본 연구결과는 KNUA012 균주가 미세조류 기반 바이오연료와 바이오매스 원료의 경제적인 생산에 있어 이상적인 자원이 될 수 있음을 제시하였다. A filamentous cyanobacterium, Limnothrix sp. KNUA012, was axenically isolated from a freshwater bloom sample in Lake Hapcheon, Hapcheon-gun, Gyeongsangnam-do, Korea. Its morphological and molecular characteristics led to identification of the isolate as a member of the genus Limnothrix. Maximal growth was attained when the culture was incubated at 25°C. Analysis of its lipid composition revealed that strain KNUA012 could autotrophically synthesize alkanes, such as pentadecane (C15H32) and heptadecane (C17H36), which can be directly used as fuel without requiring a transesterification step. Two genes involved in alkane biosynthesis-an acyl-acyl carrier protein reductase and an aldehyde decarbonylase-were present in this cyanobacterium. Some common algal biodiesel constituents-myristoleic acid (C14:1), palmitic acid (C16:0), and palmitoleic acid (C16:1)-were produced by strain KNUA012 as its major fatty acids. A proximate analysis showed that the volatile matter content was 86.0% and an ultimate analysis indicated that the higher heating value was 19.8 MJ kg<SUP>-1</SUP>. The isolate also autotrophically produced 21.4 mg g<SUP>-1</SUP> phycocyanin-a high-value antioxidant compound. Therefore, Limnothrix sp. KNUA012 appears to show promise for application in cost-effective production of microalga-based biofuels and biomass feedstock over crop plants.

한국 토착 미세조류 클로렐라 불가리스 KNUA027 균주의 생화학적 조성

홍지원 ( Ji Won Hong ),김오홍 ( Oh Hong Kim ),조승우 ( Seung Woo Jo ),김현 ( Hyeon Kim ),정미랑 ( Mi Rang Jeong ),박경목 ( Kyung Mok Park ),이경인 ( Kyoung In Lee ),윤호성 ( Ho Sung Yoon ) 한국미생물생명공학회(구 한국산업미생물학회) 2016 한국미생물·생명공학회지 Vol.44 No.3

인삼 유묘 뿌리 주변에서 자라고 있는 단세포 녹색 조류, 클로렐라 불가리스 KNUA027을 순수분리한 후 본 분리균주의 생물공학적 활용 가능성에 대해 조사를 실시하였다. 가스크로마토그래프/질량분석기를 이용한 분석 결과, 본 균주에는 영양학적으로 중요한 알파 리놀렌산(C18:3 ω3, 45.8%, 50.8 mg/g) 및 헥사데카트리엔산(C16:3 ω3, 11.8%, 13.1 mg/g)과 같은 다가불포화지방산이 풍부한 것으로 밝혀졌다. 따라서, 본 국내 토착 미세조류는 잠재적인 오메가-3 다가불포화지방산 원료가 될 수 있다고 사료된다. 또한, 바이오디젤 생산에 적합한 것으로 알려져 있는 팔미트산(C16:0, 37.1%, 41.2 mg/g) 역시 본 균주에 의해 주요 지방산 성분으로 생합성 되는 것으로 확인되었다. 근사분석 결과 KNUA027 균주의 휘발성물질 함량은 88.5%였으며, 원소분석 결과 고위발열량은 19.8 MJ/kg으로 나타났다. 본 KNUA027 균주를 이용한 연구결과는 미세조류 기반 바이오연료와 바이오매스 생산을 위한 기초자료 역할을 할 수 있을 것으로 기대된다. A unicellular green alga, Chlorella vulgaris KNUA027, was isolated from the roots of Panax ginseng seedlings and its biotechnological potential was investigated. The results of GC/MS analysis showed that C. vulgaris KNUA027 was rich in nutritionally important polyunsaturated fatty acids (PUFAs) such as alphalinolenic acid (C18:3 ω3, 45.8%, 50.8 mg/g) and hexadecatrienoic acid (C16:3 ω3, 11.8%, 13.1 mg/g). Therefore, this Korean indigenous microalga may have potential as a source of omega-3 PUFAs. It was also found that the saturated palmitic acid (C16:0, 37.1%, 41.2 mg/g), which is suitable for biodiesel production, was one of the major fatty acids produced by strain KNUA027. The proximate analysis showed that the volatile matter content was 88.5%, and the ultimate analysis indicated that the higher heating value was 19.8 MJ/kg. Therefore, the results from this research with C. vulgaris KNUA027 may provide the basis for the production of microalgae-based biofuels and biomass feedstock.

백내장 수술 시 삽입된 친수성 아크릴 인공수정체의 혼탁 2예

홍지원(Ji Won Hong),노인호(In Ho Roh),배선량(Sun Ryang Bae) 대한검안학회 2007 Annals of optometry and contact lens Vol.6 No.1

목적: 친수성 아크릴 인공수정체인 570H (RaynerⓇ, England) 삽입 후 혼탁이 발생한 환자에서 인공수정체 교환술을 시행하고 혼탁을 일으킨 침착물질을 알아보고자 하였다. 대상과 방법: 백내장 초음파유화술 후 친수성 아크릴 인공수정체인 570H (RaynerⓇ, England)를 삽입한 환자 2명에서 인공수정체 혼탁으로 인한 시력저하가 발생하여, 인공수정체교환술을 시행하였다. 제거된 인공수정체를 Alizarin red 염색, 주사현미경, X-ray 분광분석기로 분석하여 침착물질을 규명하였다. 결과: 제거된 인공수정체의 광학현미경 검사상 인공수정체 광학부에 다수의 과립상의 침착물이 관찰되었으며, Alizarin red 염색상 양성소견을 보였다. 주사현미경 검사상 다수의 과립상의 침착물이 광학부 표면에서 관찰되었으나, X선 분광분석검사상 칼슘은 관찰되지 않았고, 산소의 비중이 높게 관찰되었다. 결론: 인공수정체 제거 후 시행한 조직화학적 및 X선 분광분석상 칼슘 침착물이 관찰지 않고 산소의 비중이 높게 관찰되었다. 570H (RaynerⓇ, England) 인공수정체에서 혼탁이 발생한 경우는 국내외에서 아직까지 보고된 적이 없으며, 추후 장기적인 추적관찰이 필요하리라 생각한다. Purpose: To report the first case of opacification of hydrophilic acrylic IOL 570H (RaynerⓇ, England). Methods: Two hydrophilic acrylic IOLs (RaynerⓇ, England) were explanted from two patients who had developed decreased visual acuity after phacoemulsification and IOL implantation. Two IOLs were examined by gross and light microscopy, Alizarin red stain, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). Results: The two explanted IOLs showed identical characteristics of opacification. Visual examination detected opacification on the optic center but haptic was not opacified. The Alizarin red stain showed that the stains located under the surface (anterior side) of the IOL. Scanning electron microscopy showed particles under the surface. As a result of observing carbon, oxygen, and silicone using EDS spectrum analysis for both opacified and normal IOLs, the amount of oxygen in the opacified IOLs was much higher. Conclusions: The observation of no calcium during the EDS spectrum analysis compounded with a higher oxygen strongly indicates oxidation of some sort. Therefore, additional research is required in order to identify the cause of opacification of the hydrophilic acrylated IOL 570H.

양성 경부 낭종에서의 Picibanil(OK-432)을 이용한 경화치료 효과

홍지원,부성현,박재홍,김명구,Hong, Ji-Won,Boo, Sung-Hyun,Park, Jae-Hong,Kim, Myung-Gu 대한기관식도과학회 2008 大韓氣管食道科學會誌 Vol.14 No.2

Background and Objectives: In most cases of benign neck cysts, surgical excision has been considered as treatment of choice. However, sometimes complete excision is very difficult, and recurrences has been occured due to insufficient surgery frequently. In this point of view, non-surgical treatment has been attempted with sclerosing agents such as picibanil(OK-432). In this study, we evaluated the efficacy of picibanil sclerotherapy for benign neck cysts. Materials and methods: We retrospectively reviewed 53 patients(27 males, 26 females) who had undergone sclerotherapy with picibanil for benign neck cysts such as ranula, lymphangioma, thyroglossal duct cyst and branchial cyst. Information was gathered with respected to age, sex, number of injections, side effect and outcome of treatment. All patients were treated with intralesional aspiration of cystic contents and injection of picibanil, and followed on neck ultrasonography or neck CT. Results: 53 patients received sonoguided sclerotherapy using picibanil(OK-432). 31 patients(41.3%) showed total shrinkage, near total shrinkage(more than 90% of volume) in 7 patients(9.3%), marked shrinkage(more than 70%) in 5 patients(6.6%) and partial shrinkage(less than 70%) in 17 patients. 15 patients(20%) reaveled no response and 8 patients showed recurrences with repeated sclerotherapy. The side effects of therapy were observed by symptoms such as fever, localized pain and odynophagia. However, these complications disappeared after several days in all cases. Conclusions: We recognized that picibanil(OK-432) sclerotherapy for benign neck cyst is a safe and effective procedures as a primary treatment before considering surgery.