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허준원 ( Joon Won Huh ),유지숙 ( Jisook Yoo ),김민수 ( Min Soo Kim ),최광현 ( Kwang-hyun Choi ),박향준 ( Hyang-joon Park ),주민숙 ( Mihn-sook Jue ) 대한피부과학회 2016 大韓皮膚科學會誌 Vol.54 No.10
Segmental neurofibromatosis is a rare form of neurofibromatosis that is characterized by neurofibromas and/or cafe au lait macules, limited to one region of the body. The neurofibromas of segmental neurofibromatosis are most commonly occupied by either a cervical or a thoracic dermatome. Segmental neurofibromatosis on the face is extremely rare, and only 10 cases have been described so far. Herein, we report a case of segmental neurofibromatosis on the V1 dermatome for its rarity and unusual location. (Korean J Dermatol 2016;54(10):811∼813)
Pegylated 인터페론 알파 2a 병변내 주사로 치료한 고전형 카포시 육종 3예
정영인 ( Young In Jeong ),허준원 ( Joon Won Huh ),김건 ( Geon Kim ),김은정 ( Eun Jung Kim ),박향준 ( Hyang Joon Park ),주민숙 ( Mihn Sook Jue ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.9
Kaposi sarcoma (KS) is a multifocal proliferative vascular tumor often caused by human herpes virus 8. Among the four subtypes of KS, classic KS (CKS) is usually chronic, persisting over many years, but is not life threatening. Because the natural history of KS varies, many kinds of therapeutic option for CKS are available and their assessment may be difficult. We experienced three cases of CKS showing HHV-8 positive in biopsy, no history of immunosuppression and HIV infection, normal chest X-ray, no metastasis, and successfully treated with intralesional injection of Pegylated Interferon-α2a (Peg-IFN-α2a). After an intralesional Peg-IFN-α2a injection of 180 mcg/0.5 ml was administered once a week for 4 months, the size and induration of the lesions reduced greatly and the colors faded away. Histopathological examination of the resolved lesions did not show any evidence of KS with negative HHV-8 results. To the best of our knowledge, this is the first report in the literature for the treatment of CKS with intralesional Peg-IFN-α2a injection. (Korean J Dermatol 2014;52(9):646∼650)
Narrowband UVB 치료에 의해 호전된 습진양 자반병
정영인 ( Young In Jeong ),허준원 ( Joon Won Huh ),김건 ( Geon Kim ),주민숙 ( Mihn Sook Jue ),박향준 ( Hyang Joon Park ),김은정 ( Eun Jung Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.4
Eczematid-like purpura of Doucas and Kapetanakis is a type of pigmented purpuric dermatoses. It is clinically characterizedby pruritic seasonal eruptions occurring in the spring and summer, and histopathologically characterized byspongiosis and parakeratosis in the epidermis and by the lymphocyte-mediated leakage of erythrocytes from capillariesin the papillary dermis. We report a case of eczematid-like purpura of Doucas and Kapetanakis that showedclinical improvement with narrowband UVB (NB-UVB). The patient was a 66-year-old man with pruritic,well-demarcated scaly purpuric patches on his feet that appeared 2 months prior. A histopathological study showedmild superficial perivascular lymphocytic infiltration, focal spongiosis with exocytosis, and erythrocyte leakage. Weinitiated treatment with an oral antihistamine, ascorbic acid, and a topical steroid, but the lesion was aggravated. Wetherefore treated the patient with NB-UVB for 6 months, and the lesions regressed progressively with residual postinflammatoryhyperpigmentation.