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한일수 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.1
Edema is the symptom caused by various disease, divided into localized and generalized edema. Edema called soo-jong in oriental medicine. Soo-jong is classified as yang-soo(yang type edema) and eum-soo(yin type edema). However the confused condition appear in the clinical case that have some indistinct to classification of yang-yin. So I study for general prescription of soo-jong and point out the Gwakrhyeong-tang(GRT). This prescription are combined with Gwakhyangjeonggi-san and Orhyeong-san. Two severe generalized edema patient were given GRT in 3 days. After taking GRT, the patient's whole body edema and general condition were improved. Key word : whole body edema, Gwakrhyeong-tang(GRT)
六味地黃湯, 八味地黃湯 및 加味地黃湯 생쥐의 服腔大食細胞 活性에 미치는 影響
韓一洙,金哲中 대전대학교 韓醫學연구소 1997 혜화의학회지 Vol.6 No.1
In order to investigate the effects of YOOKMIJIHWANGTANG, GAMIJIHWANGTANG and PALMIJIHWANGTANG on the various immune responses, the chemotactic, adherent, nitric oxide release ability of macrophages were studied in vivo and in vitro. The results obtained were follows 1. The total number of peritoneal exudate cells from mice injected with three drugs were 2∼3 times more than those from the PBS. 2. The administration of three drugs enhanced significantly the Fc receptor mediated activity(phagocytosis, rosette formation activity). 3. The administration of three drugs enhanced significantly the chemotactic activity of peritoneal macrophages. 4. The administration of three drugs enhanced significantly the adherent activity of macrophages and neutrophils. 5. The administration of GAMIJIHWANGTANG and PALMIJIHWANGTANG enhanced significantly the chemotatic activity of macrophages (p<0.01). And also the administration of YOOKMIJIHWANGTANG enhanced significantly the chemotatic activity of macrophages(p<0.05). 6. The administration of GAMIJIHWANGTANG and enhanced signifi- cantly the chemotatic activity of neutrophils(p<0.01). And also the administration of YOOKMIJIHWANGTANG and PALMIJIHWANGTANG enhanced significantly the chemotatic activity of neutrophils(p<0.05). From above findings, it is suggested that YOOKMIJIHWANGTANG, GAMIJIHWANGTANG and PALMIJIHWANGTANG seems to produce the increase of immune response such as the Fc receptor activity, chemotactic activity, adherent activity, nitrate release of macrophages. From the above results, the GAMIJIHWANGTANG among three drugs may be the most useful drug having immunostimulating effects.