웅담·우황약침액이 다종의 각막염 유발균에 미치는 영향

한나영,서형식,Han, Na-Young,Seo, Hyung-Sik 대한약침학회 2010 Journal of pharmacopuncture Vol.13 No.2

Objectives : This experimental study was performed to investigate the effect of Fel Ursi & Bovis Calculus pharmacopuncture solution(FUBCPS) manufactured by using alcohol/water extraction method for identify ing the use of it as eyedrops. Methods: FUBCPS was manufactured by using alcohol/water extraction method. Measure the size of inhibition zone and MIC(Minimum Inhibition Concentration) after administering FUBCPS on bacterial species. Staphylococcus aureus. Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum and Candida albicans, which cause keratitis. Administering cravit(Levonoxacin medicine) on bacterial species also performed to compare the anti-bacterial potency of this material, measured by using the size of inhibition zone Results : After administering FUBCPS on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans). there was no response to MIC and there was no anti -bacterial potency also. Conclusions : This study suggests that FUBCPS dose not have anti-bacterial effects on bacterial species which cause Keratitis. These study result recommends that we need to research more on herbal medicines of eye drop which have anti-bacterial effects on keratitis

녹용에서 당 함유 물질의 분리 및 분석

한나영,전길자 ( Na Young Han,Gil Ja Jhon ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.5

The major component of glycolipids in antler was investigated by Folch-Suzuki partition method, Sephadex G-50 chromatography, DEAE-Sephadex A-25 chromatography, HPLC, and FAB-MS. Glycolipids, extracted in aqueous phase by chloroform-methanol-0.88% KCl aqueous solution, were analyzed on Sephadex G-50 column and most glycolipids containing band 1 were eluted in void volume because of the formation of micelles. The major fractions pooled from Sephadex G-50 column were eluted before gradient elution on DEAE-Sephadex A-25 column due to neutral property. Band 1 extracted from HPTLC plate was injected on HPLC column(μ-Bondapak NH₂ column) and four peaks were separated. The fractions containing major peak(3.17 min, 48.5%) were pooled and analyzed by negative-ion FAB-MS. As the result, it has been identified that the molecular weight of major component is 1058 and structural fragments is 98-98-142-98-142-98-142-98-142 or 98-240-240-240-240.

녹용중의 Gangliosides 분리 및 분석

한나영,전길자,Han, Na-Young,Jhon, Gil-Ja 생화학분자생물학회 1994 한국생화학회지 Vol.27 No.5

본 연구에서는 녹용중에 존재하는 gangliosides 성분을 조사하였다. Folch-Suzuki 분배법에 의해 수용액층으로 분배된 당지질 성분을 Sephadex G-50 column chromatography와 투석으로 정제한 후 용매추출법을 이용하여 ganglioside 성분만을 분리하였다. DEAE-Sephadex A-25 column chromatography와 HP-TLC로 분석한 결과 녹용의 70% 에탄올 추출액에는 GM3, GM4가 주요 ganglioside이었으며 GM1과 GM2가 소량 존재하였으나, chloroform/methanol 추출물에는 GM1이 주요 ganglioside이었다. 녹용 30g중에 $0.437{\mu}mol$의 ganglioside-bound sialic acid가 존재하였다. To determine contents of gangliosides in deer antler, we separated glycolipid from deer antler according to Folch-Suzuki partition method. The glycolipid was then purified by Sephadex G-50 column chromatography and dialysis. The gangliosides were purified from the separated glycolipid by solvent extraction, 2D-HPTLC, and DEAE-Sephadex A-25 chromatography. We found that GM3 and GM4 were major gangliosides and GM1 and GM2 were minor gangliosides in 70% ethanol extract from deer antler. However, GM1 was major ganglioside in chloroform/methanol extract from deer antler. The amount of ganglioside· bound sialic acid was $0.437{\mu}mol$/30g deer antler.

융합연구개발 성공사례에서 파악한 중소기업 융합유형

한나영,홍재범,Han, Na-Young,Hong, Jae-Bum 한국벤처창업학회 2012 벤처창업연구 Vol.7 No.2

본 연구는 중소기업 융합개념과 융합유형을 명확히 정립하고 중소기업 융합 사례를 유형별로 파악하여 융합을 통한 중소기업 경쟁력 증대에 도움이 되고자 하였다. 중소기업 융합유형은 Deloitte(2009)에서 제시한 기술과 산업, 가치개선과 창출 2가지 차원을 수용하여 기술은 투입, 산업은 산출의 차원에서 정의하여 중소기업 융합을 기술개선-시장확대형, 기술개선-시장창출형, 기술창출-시장확대형, 기술창출-시장창출형 4가지로 나누고 중소기업 융복합기술개발사업 우수사례집('11년 8월)에 소개된 기업들을 중심으로 융합유형을 분류하였다. 그 결과, 전체 13개의 사례 중 기술개선-시장확대형 5개, 기술개선-시장창출형 4개, 기술창출-시장확대형 3개, 기술창출-시장창출형 1개 순으로 나타나 중소기업의 경우 기술창출 보다는 기술개선에, 시장창출보다는 시장확대에 초점을 두고 융합이 이루어지고 있었다. 이러한 중소기업 융합 유형별 사례분석을 통해 파악할 수 있는 것은 중소기업이 융합을 통한 신기술이나 신시장을 창출하는 것이 매우 어렵다는 것이다. 따라서 중소기업은 기술개선을 통한 시장확대를 융합의 목표와 결과로 생각하고 있는 것으로 추정된다. 국가의 신성장동력을 육성하기 위해서 신기술이나 신산업 창출도 중요하지만 중소기업의 현실을 고려한 정책지원도 함께 고려해야 한다. This study clearly defined the idea of convergence of small and medium companies and convergence types and understood convergence case of small and medium companies for each type in order to help enhancement of competitiveness of small and medium companies. The convergence type of small and medium companies accepted two levels including technology and industry and value improvement and creation suggested by Deloitte(2009) and it was classified into technology improvement-market expansion type, technology improvement-market creation type, technology creation-market expansion type, and technology creation-market creation type based on the companies introduced in the excellent casebook of convergence and integration technology development business of small and medium companies(August 2011). As a result, it was shown as 5 cases of technology improvement-market expansion, 4 cases of technology improvement-market creation, 3 cases of technology creation-market expansion, and 1 case of technology creation-market creation among the total 13 cases. Therefore, small and medium companies are focusing on technology improvement than technology creation and market expansion than market creation. What we can understand through cases analysis on convergence types of small and medium company is that it is very difficult for small and medium companies to create new technology or new market through convergence. Thus, small and medium companies consider market expansion through technology improvement as the objective and result of convergence. It is important to create new technology or new industry to cultivate new growth engines of the nation, but policy support that cares about reality of small and medium companies must be considered at the same time.

녹용중의 Gangliosides 분리 및 분석

한나영,전길자 ( Na Young Han,Gil Ja Jhon ) 생화학분자생물학회 1994 BMB Reports Vol.27 No.5

To determine contents of gangliosides in deer antler, we separated glycolipid from deer antler according to Folch-Suzuki partition method. The glycolipid was then purified by Sephadex G-50 column chromatography and dialysis. The gangliosides were purified from the separated glycolipid by solvent extraction, 2DHPTLC, and DEAF-Sephadex A-25 chromatography. We found that GM3 and GM4 were major gangliosides and GM1 and GM2 were minor gangliosides in 70% ethanol extract from deer antler. However, GM1 was major ganglioside in chloroform/methanol extract from deer antler. The amount of ganglioside-bound sialic acid was 0.437 μ㏖/30 g deer antler.

비치(鼻痔)(Nasal polyp)의 외치법(外治法)에 대한 문헌적(文獻的) 고찰(考察)

한나영,서형식,Han, Na-Young,Seo, Hyung-Sik 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.3

Object : Understanding the importance of the external treatment of nasal polyps and let know the necessity of development of the effect of herb medicine to use in these days. Method : I investigated about 12 oriental medical texts which recorded the external treatment of nasal polyps. I separated them to three part (prescription, herb medicine, the way of making the external application) and check the frequency. Also compared the external treatment of oriental medicine and western medicine. Result : 1. Prescription: There are 48 prescriptions -Nyosasan is used 4 cases, Gwajungsan is used 2 cases and others only 1 case each. 2. Herb-med: There are 67 herb medicines - Herba Asari(細辛) is used 15 cases, Pedicellus Melo (瓜?) is used 11 cases, Alunite(白礬) is used 10 cases, Realgar(雄黃)is used 9 cases. 3. The way of making the external application: obstructive method is used 19 cases, attaching method is used 9 cases, blowing method is used 8 cases, plaster method is used 7 cases, pouring method is used 3 cases. 4. The treatment takes about 1day to 15days and the soften nasal polyps like a water can be expect the positive prognosis. Conclusion: The external treatment is very important to treat nasal polyps. So we need to research more on eliminating the toxicity of the herb medicine and develop the convenient way of using the external treatment.

연구논문 : 고용관련 트라우마가 조직시민행동과 노조관련행동지향성에 미치는 영향의 탐색적 연구

한나영 ( Na Young Han ),윤영삼 ( Yeong Sam Yun ) 한국인적자원관리학회 2010 인적자원관리연구 Vol.17 No.3

심리적 임파워먼트와 조직시민행동의 관계에 대한 성취욕구의 조절효과 검증 : 부산지역 특급호텔 종사자를 중심으로

한나영(Na-Young Han),김영조(Young-Joe Kim) 한국인사·조직학회 2011 인사조직연구 Vol.19 No.1

본 연구는 호텔 직원들을 대상으로 심리적 임파워먼트가 조직시민행동의 수행에 어떠한 영향을 미치는지, 그리고 구성원의 성취욕구가 이들 관계에 대해 어떠한 형태의 조절효과를 갖는지 분석하는 것을 목적으로 하고 있다. 부산 지역 6개 특급 호텔을 대상으로 설문조사를 실시하여 275부의 설문지가 회수되었으며, 이중에 설문응답이 불성실한 21부를 제외한 후 254부의 자료를 실제 분석에 활용하였다. 연구결과, 인구통계변수들은 조직시민행동을 유의하게 설명하지 않는 반면, 심리적 임파워먼트는 유의하게 설명하는 것으로 나타났다. 특히, 과업의미성(meaning)은 조직시민행동의 다섯 가지 차원들 중에 적극 참여행동, 양심적 행동과 비불평 행동에 유의적인 영향을 미치고 있고, 영향력(impact)은 적극 참여행동에만 유의적인 영향을 미치는 것으로 나타났다. 한편, .10의 유의수준을 기준으로 했을 때는 과업의미성은 다섯 차원의 조직시민행동 모두에 유의한 영향을 미치고 있고, 효능감(competence)은 이타적 행동, 배려적 행동과 비불평 행동을 유의하게 설명하는 것으로 나타났다. 반면에, 자율결정권은 다섯 가지 차원의 조직시민행동과 모두 유의적인 관계를 보이지 않고 있다. 다음으로, 성취욕구가 강한 구성원일수록 조직시민행동을 더 적극적으로 수행하는 것으로 나타났고, 성취욕구의 조절효과에 대한 분석결과 과업의미성과 성취욕구의 상호작용 항목만이 조직시민행동(이타적 행동과 양심적 행동)을 유의하게 설명하는 것으로 나타났다. 구성원의 성취욕구가 강할수록 조직시민행동에 대한 심리적 임파워먼트의 긍정적 효과가 확대되어 나타날 것이라고 가설을 설정하였는데, 가설에서 예상한 것과 반대로 성취욕구가 강한 구성원들은 과업의미성과 조직시민행동이 유의적인 관계를 갖고 있지 않는 반면, 성취욕구가 약한 구성원들은 과업의미성이 높아질수록 조직시민행동을 더 적극적으로 수행하는 것으로 나타났다. 이러한 연구결과가 갖는 시사점에 대해 논의하였다. This study is aimed to examine a positive impact of psychological empowerment of employees on their organizational citizenship behaviors(OCBs), and moderating effect of the need for achievement(nAch) on relationship between psychological empowerment and OCBs. Because empowered employees believe that they are competent and autonomous and regard their tasks as important and valuable, they are more likely to be motivated to proactively perform OCBs and to show job responsibilities. Thus, we hypothesize that psychological empowerment is positively related to OCBs(H1). Meantime, psychological empowerment may not affect all employees in the same way. We suggest that the need for achievement can enhance positive impact of psychological empowerment on OCBs. Therefore, we hypothesize that nAch moderates the relationship between psychological empowerment and OCBs(H2). Specifically, we expect correlation between psychological empowerment and OCBs will be stronger amongst individuals with high nAch than amongst individuals with low nAch. To test the hypotheses proposed, data were obtained from a sample of customer-contact employees working for six luxury hotels in Busan Metropolitan City. 275 out of 330 questionnaires were returned from the six hotels(response rate 83.3%). After excluding 21 unusable cases which had unacceptable level of missing data, 254 cases were used for analysis. The survey consisted of nine measures: four dimensions of psychological empowerment, five dimensions of OCBs, and need for achievement. Psychological empowerment was defined and measured with four dimensions using Spreitzer’s(1995) scales: meaning, competence, self-determination, and impact. Podsakoff et al.’s(1990) scales were used to measure five dimensions of OCBs: altruism, courtesy, sportsmanship, conscientiousness, and civic virtue. Need for achievement was conceptualized as an employee’s tendency to strive to overcome obstacles and to accomplish challenging goals and measured with 5 items. In addition, we controlled for four demographic variables such as age, gender, length of service, and position. The results supported the hypothesis that the dimensions of psychological empowerment are positively related to the OCBs of service workers. Meaning had a significant positive impact on civic virtue, conscientiousness, and sportsmanship out of five dimensions of OCBs, and impact had a positive influence on only one dimension of OCBs(i.e., civic virtue). Competence was a significant predictor of altruism, courtesy, and sportsmanship at .10 significance level, but self-determination was not related to any dimensions of OCBs. These results imply that meaning and competence are more powerful predictors of OCBs than other types of empowerment. Therefore, empowered employees, especially those who feel their job is meaningful and believe they have the capacity to perform work activities with skills, are more actively engaged in the OCBs. It was found that the need for achievement had not only a direct impact on the OCBs but also a moderating effect on the relationship between meaning and OCBs. Contrary to the hypothesis that expected a stronger relationship between empowerment and OCBs among individuals with higher nAch, the result showed the that the impact of meaning on altruism and conscientiousness was significant and positive among employees with low nAch while it was not significant among employees with high nAch. This result implies that psychological empowerment plays a vital role in encouraging employees with low nAch to perform OCBs, but not necessarily for employees with high nAch since achievement-oriented employees tend to overcome obstacles and strive for challenging goals. These findings suggest that not only psychological empowerment but also employees’ need for achievement is important to induce employees to perform OCBs. The results have implication for human resource management policies as well as organizational interv

병원고객의 불량행동이 감정부조화와 감정고갈을 매개로 이직의도와 고객지향성에 미치는 영향에 관한 연구

한나영(Han Na Young),배상욱(Bae Sang Wook) 한국산업정보학회 2017 한국산업정보학회논문지 Vol.22 No.5

본 연구에서는 고객 불량행동이 서비스 종사원의 감정부조화에 미치는 영향을 살펴보고 감정부조화가 감정고갈에 미치는 영향과 감정고갈이 이직의도와 고객지향성에 미치는 영향을 살펴보고자 한다. 또한 고객 불량행동과 감정부조화 간의 관계에서 감정노동전략(표면행동, 내면행동)의 조절효과를 살펴보고자 한다. 병원에 종사하는 종사원들을 대상으로 설문조사를 실시하였으며 그 결과는 다음과 같다. 첫째, 불량행동은 감정부조화에 정(+)의 유의적인 영향을 미치는 것으로 나타났다. 둘째, 감정부조화는 감정고갈에 정(+)의 유의적인 영향을 미치며 셋째, 감정고갈은 이직의도에 정(+)의 유의적인 영향, 고객지향성에는 부(-)의 유의적인 영향을 미치는 것으로 나타났다. 끝으로 위계적 회귀분석을 통해 종속변수인 감정부조화에 대해서, 불량행동과 조절변수인 표면행동의 상호작용효과는 유의한 것으로 나타났으나 불량행동과 조절변수인 내면행동의 상호작용효과는 유의하지 않은 것으로 나타났다. This Study Examined the Effects of Disgruntled Customers’ Behaviors on the Emotional Dissonance of Service Workers, the Effects of Emotional Dissonance on Emotional Exhaustion, and the Effects of Emotional Dissonance on Turnover Intention and Customer Orientation. In Addition, this Study Examined the Moderating Effects of Emotional Labor Strategies(both surface acting and deep acting), in the Relationship Between Customers’ Disgruntled Behaviors and Emotional Dissonance. A Survey was Conducted on Hospital Workers and Drew the Following Results. First, Disgruntled Behavior had a Positively Significant Effect on Emotional Dissonance. Second, Emotional Dissonance had a Positively Significant Effect on Emotional Exhaustion. Third, Emotional Exhaustion had a Positively Significant Effect on Turnover Intention but Negatively Significant Effect on Customer Orientation. Finally, According to a Hierarchical Regression Analysis, Disgruntled Behavior and a Moderating Variable, Surface Acting had a Significant Interaction Effect on Dependent Variable, Emotional Dissonance, but Disgruntled Behavior and a Moderating Variable, Deep Acting did not.

감정노동이 반생산적 과업행동에 미치는 영향에 관한 연구

한나영(Han, Na-Young),배상욱(Bae, Sang-Wook) 한국산학기술학회 2015 한국산학기술학회논문지 Vol.16 No.10

본 연구는 의료기관 종사자들의 감정노동과 직무만족, 조직몰입 및 반생산적 과업행동 간의 관계를 통합적으로 살펴 보기 위하여 의료기관 종사자들을 대상으로 설문조사를 실시하고 공변량 구조방정식모형을 통해 실증분석을 하였다. 실증분 석 결과 첫째, 감정노동 차원 중 감정표현빈도는 직무만족에 유의적인 영향을 미치지 않는 것으로 나타났으나 감정표현주의 정도, 감정부조화는 직무만족에 부(-)의 유의적인 영향을 미치는 것으로 나타났다. 둘째, 직무만족은 조직몰입에 정(+)의 유의 적인 영향을 미치는 것으로 나타났으며 셋째, 조직몰입은 개인·조직 대상 반생산적 과업행동 모두에 부(-)의 유의적인 영향을 미치는 것으로 나타났다. 본 연구결과는 의료기관 종사자들이 직무를 수행하는데 있어 감정노동이 부정적인 결과를 초래하 기 때문에 그들이 업무수행 중에 겪게 되는 감정노동을 경감시킬 수 있는 방안에 관심을 가질 필요가 있다는 것을 보여주고 있다. This research conducted a survey of the workers in medical institutions and carried out empirical analysis through covariance structure equation modelling in order to examine the relationship among emotional labor, job satisfaction, organizational commitment, and counterproductive work behaviors of medical institution workers. The results of the empirical analysis are as follows; First, the frequency of emotional expression, one of the dimensions of emotional labor, did not have a positive influence on job satisfaction, but both the degree of emotional expression attentiveness and emotional dissonance had a negatively significant effect on job satisfaction. Second, job satisfaction had a positively significant effect on organizational commitment. Third, organizational commitment had a negatively significant effect on counterproductive work behaviors toward both individuals and organizations. This research result shows that it is necessary to pay attention to drawing a plan to reduce emotional labor that workers in medical institutions experience since emotional labor causes them to get negative results while they are performing their duties.