Frontier Humor의 傳統과 Mark Twain(Ⅰ) : Frontier Humor의 전통과 Mark Twain(Ⅰ)

한구석 釜山大學校 1964 論文集 Vol.5 No.1

직업적 연폭로에서 혈중 연량 수준에 따른 선별검사로서의 혈중 ZPP 검사의 타당도

한구석,안현철,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to evaluate the validity of current screening criteria of lead exposure and to provide effective information for the better health management of lead workers, author investigated the interrelationship between blood lead and blood zinc protoporphyrin(ZPP) and evaluate the validity of blood zinc protoporphyrin as the screening test and blood lead as gold standard of diagnostic test. The total of 2245 lead workers (male workers: 1982, female workers : 263) from 12 lead using industries were studied. Blood lead, ZPP, hemoglobin and hematocrit were selected as lead exposure variables. Personal information on sex, age and work duration were also checked. Blood lead was measured with flameless atomic absorption spectrometry (model: Hitachi 8100) using standard addition method. Blood ZPP was measured with portable hematoflurometer (model: Aviv 206). The results obtained were as follows: 1. The mean blood lead of all lead workers were 0.7±14.3㎍/㎗(Male: 31.0±14.4㎍/㎗, Female: 28.2±12.9㎍/㎗), whereas the mean blood ZPP of those were 68.1±47.5㎍/㎗(Male: 63.9±43.7㎍/㎗, Female: 100.1±61.0㎍/㎗). The mean value of hemoglobin and hematocrit of all lead workers were 14.5±1.5g/㎗(Male: 14.7±1.3g/㎗, Female: 12.3±1.2g/㎗) and 45.4±3.6(Male: 46.2±2.8, Female: 39.5±3.1) respectively. 2. Validity of test using blood zinc protoporphyrin as screening test for blood lead levels of 30㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 50 and 90 ㎍/㎗ of ZPP respectively, showing 50 and 60 ㎍/㎗ of ZPP for all lead workers. While those test for blood lead levels of 40㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 and 90 ㎍/㎗ of ZPP respectively, showing 60 ㎍/㎗ of ZPP for all lead workers, those test for blood lead levels of 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 or 70 and 100 ㎍/㎗ ZPP respectively, showing 60and 70 or 80 ㎍/㎗ of ZPP for all lead workers. 3. Predictive value of test using blood zinc protoporphyrin as the screening test for different blood lead levels of 30, 40, 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that positive predictive value of screening test were decreased by the increase of blood lead level regardless of csreening criteria value ZPP and negative predictive value of screening test were increased accordingly regardless of screening criteria value of ZPP. On the other hand, within same blood lead level as a gold standard positive predictive values were inceased by the increase of screening criteria value of ZPP, whereas the negative predictive value were decreased accordingly by the the increase of screening criteria value of ZPP. 4. The correlation analysis of all lead workers among study variables revealed that CPbB and natural log transformation ZPP(LZPP) were better correlated with other variables and found to be better estimate than PbB and ZPP themselves. The age was correlated with all other variables, but the work duration was not. The correlation analysis of male and female workers among study variables revealed the same results with all lead workers. 5. The slope of simple linear regression of CPbB (independent variable) with ZPP in female workers(3.223)was steeper than in male workers(2.144). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But there was no slope difference between two groups divided by their work duration of 2 years less and more. The slope of simple linear regression of CPbB lead (independent variable)with ZPP in lead workers whose blood lead were higher than 30㎍/㎗and 40㎍/㎗ were steeper than those whose blood lead were less than 30㎍/㎗ and 40㎍/㎗. 6. The slope of simple linear regression of CPbB (independent variable) with ZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead. 7. The slope of simple linear regression of CPbB (independent variable) with LZPP in female workers(0.0308was steeper than in male workers(0.0253). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But where was no slope difference between two groups divided by their work duration of 2 years less and more. While the slope of simple linear regression of CPbB lead (independent variable) with LZPP in lead workers whose blood lead were hogher than 30㎍/㎗ was not steeper than those whose blood lead were less than 30㎍/㎗, there was no slope difference between two groups whose blood lead were less than 40㎍/㎗ and more than 40㎍/㎗. 8. The slope of simple linear regression of CPbB (independent variable) with LZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead, but the difference was not significant then that of CPbB and ZPP. With above results, it is recommended that the screening criteria value of ZPP should be down to 60-70㎍/㎗ from 100㎍/㎗ for male lead workers and screening criteria of ZPP for female lead workers was all right with current value of 100㎍/㎗. So it is recommended to make different screening criteria of ZPP for male and female workers like the hemoglobin and hematocrit screening criteria. It is also preferable to use CPbB and LZPP rather than uncorrected PbB and ZPP in the evaluation of lead exposure for lead workers.

外鼻 再建의 治驗例 : Case Report

한구석,이종원,이택호 인제대학교 1980 仁濟醫學 Vol.1 No.1

외비부(外鼻部)의 결손은 외상, 감염성 질환 및 선천성기형등에 의하여 초래될 수 있으며 이러한 환자 3예에 대하여 본 교실에서는 composite graft 및 Indian forehead flap을 이용한 재건수술을 시행하여 만족스런 결과를 얻어 문헌적 고찰과 함께 보고하는 바이다. Defect of the ala nisi often arise following malignancy, irradiation, burn, traffic accident, infectious disease and trauma and from congenital anomalies. The authors recently examined three patients with partial defect of ala nasi and performed reconstructive surgery utilizing composite graft and modified Indian forehead flap. The results were satisfactory and we therefore wish to report our cases with a review of literature.

외비 성형술의 임상적 고찰

이택호,이종원,정해광,한구석 大韓成形外科學會 1980 Archives of Plastic Surgery Vol.7 No.2

Rhinoplasty has become one of the most common operations in plastic surgery.Good results in plastic surgery of the nose are not necessarily assured by technical skill and a knowledge of basic and surgical anatomy and of the chronology of surgical steps. The basic steps in rhinoplasty remain the same as they were when the operation was introduced by Joseph.But it was constantly undergoing changes. Our purpose in this article is to introduce the most significant changes in rhinoplasty techniques since it first received wide acceptance.

外鼻部 部分全層缺損의 治驗例

尹吉鎔,李澤浩,韓九錫 大韓成形外科學會 1979 Archives of Plastic Surgery Vol.6 No.1

Partial defect which involve the full thickness of the ala nasi often arise following traffic accident, burn, gun shot wound, and bite wound, as secondary defect of malignant tumors and infectious disease, and from congenital anomalies. The authors recently examined three patients with partial defects of ala nasi and performed reconstructive surgery utilizing modified Indian forehead flap and composite graft. The results were satisfactory and we therefore with to report our cases with a review of literature.

우리나라 축전지 제조업 근로자들의 연폭로에 관한 연구

한구석,안규동,강필규,황규윤,김용배,리갑수,이병국,안익수,이규종,김화성 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

In order to investigate the level of lead absorption of lead workers and to evaluate the effect of blood lead on blood zinc protoporphyrin(ZPP) and prevalence of lead related symptoms, 1,782 lead workers(male: 1,506, female: 276) from 8 storage battery industries were studied. Selected variables as indices of lead exposure were blood lead, blood ZPP, and hemoglobin(HB). Fifteen questionnaires of lead related symptoms were provided to all leak workers and filled up by themselves and confirmed by medical doctors. Personal lead variables such as age, work duration, smoking and drinking habits were also collected. The results were follows: 1. While the mean blood lead of lead workers of all lead companies was 31.0±13.0 ug/100ml(male: 31.5±12.9 ug/100ml, female: 27.9±13.3 ug/100ml), the mean blood ZPP of all lead workers was 66.7±54.1 ug/100ml (male: 59.6±43.3, female: 105.3±83.0 ug/100ml). The mean hemoglobin of male lead workers was 15.7±1.3 gm/100ml and that of female lead workers was 13.0±1.3 gm/100ml. 2. The percentage of lead workers whose blood lead was over 60.0 ug/100ml and 40.0-59.9 ug/100ml was 2.81% and 19.08%, respectively. On the other hand, the percentage of lead workers whose blood ZPP was over 150ug/100ml and 100-149 ug/100ml was 5.89% and 8.31%, respectively. 3. The slopes of simple linear regression of blood lead(independent variable) and blood ZPP in female lead workers was significantly steeper than that of male lead workers. The slope of storage battery industries with better working condition in terms of low air concentration of lead were less steeper than those with poor working condition with high mean air concentration of lead. 4. Stepwise multiple regression analysis, using overall symptom prevalence as a dependent variables, blood lead, blood ZPP, hempglobin, age, work duration, drinking and smoking habits as independent variables, indicated that only drinking habit and age were significantly contributed to the dependent variable.

구순열 아동의 지능과 학교성적 및 신장발육상태에 관한 비교관찰

韓九錫,丁海光,李澤浩 大韓成形外科學會 1980 Archives of Plastic Surgery Vol.7 No.1

The purpose of this study was to investigate the intellectual and physial status of cleft lip children seen frequently in our country and to be some help in their psychological rehabilitation and social life of these children. The subjects were chosen among the 482 patients who visited Pail Foundation Hospital and Red Cross Hospital in Seoul and other parts of Korea for the purpose of correction of cleft lip from April 1, 1978. to Dec. 31, 1979. Among these pre-school children who would not read Korean, excluded and 85 children with cleft lip attending school were chosen. Intelligence quotient Test were performed and letters were went to the school teachers of the 85 children inquiring about their school grades and height growth. 72children were supplied with data and analysis was made based ob these 72 children. Results of analysis. 1. Average I.Q. of children with cleft lip was 95.63% and 50.6% was in the average range 90 to 109 with the conclusion that their I.Q. is with in the average range. 2. The school grades of these children showed improvement according to their levels in school with 31.4% in elementary school, 31.6% in junior high school and 61.1% in senior high school. 3. Their height development was 51.4% in elementary school, 73.7% and 72.2% in junior and senior high school respectively showing that their height development was better than normal children. In conclusion, their was no difference in intelligence, school grades and height development between children with cleft lip and normal children.

유방증대술후 혈종이 구형구축 발생에 미치는 영향에 대한 임상적 고찰 : -CLINICAL ANALYSIS-

한구석,함기선,김수철,한승혜 大韓成形外科學會 1985 Archives of Plastic Surgery Vol.12 No.3

Spherical contracture around breast prosthesis continues to be a major complication following augumentation mammoplasty, in spite of the efforts that have been done to reduce it. According to many reported data, the incidence veries from 4 to 74 percent. The etiology of the spherical contracture is speculative and probably multifactorial, but that has been focused to few factor including subclinical infection, hematoma and organized seroma. We suggest that hematoma is the most significant factor about it. So many plastic surgeons routinely drain into the dissected pockets postoperatively in order to eliminate the hematoma. Our studies are purposed of the three aspects: The first, How much volume of bloody fluid were drained during first 24hrs postoperatively even if dry pocket was considered intraoperatively. The second, How much hemoglobin value be contained in the evacuated fluid. The third, How much were correlated incidence of spherical contracture with above 2 factors. We studied 76 breasts(38 patients) who had performed bilateral augumentation mammoplasty at Ohin aesthetic surgery center during from January 1983 to June 1984, all had the smooth surfaced soft law profile and employed the drained technique using Hemo-vac. We have adopted Baker's classification for grading the severity of spherical contracture. We could be summarized and the results were as follows: 1. All cases were drained some amount of bloody fluid from 4cc to 85cc and the average amount of 18.6cc. 2. The hemoglobin value of the evacuated fluid was ranged from 3.2mg% to 12.7mg% and the average value of 7.6mg%. 3. There was tendency to the smaller volume of bloody evacuated fluid the lower hemoglobin level. 4. The amount of drained fluid and it's hemoglobin value were closely related with the incidence of spherical contracture around prosthesis in acceptable group (Grade Ⅰ & Grade Ⅱ) but not in unacceptable group (Grade Ⅱ & Grade Ⅳ).

두경부에 발생한 미만성 신경섬유종증의 치험예

윤길용,한구석,이택호 大韓成形外科學會 1978 Archives of Plastic Surgery Vol.5 No.1

Diffuse neurofibromatosis or, von Recklinghausen's disease is a herediatary, often congenital and sometimes familial disturbance in supportive tissue of the nervous system, both central and peripheral. It usually involves the skin. It may involve the skeleton and disturbances in other systems such as the endocrine and gastro-intestinal tract have reported. The authors experienced a case of neurofibromatosis of the head and neck. The patient was 21 year-old male. Examination of the left temporal and cheek showed light brown patch and soft painless pedunculated nodule formed hanging mass. Also cafe-au-lait spots and freckling showed on the back, anterior chest wall and both axillary vaults. Moderate ptosis was noted at the left eyelid because of the hanging mass. Histologically, the preparation showed whorls of spindle cells in fibrous tissue with wavy or interlacing fashion and melanin deposition in the basal cell layer of the skin. It was treated by the use of local tissue flap after subtotal excision of the mass.

신체훈련이 척수장애인의 혈중 지질성분에 미치는 영향

진영수,한구석,최승권,김의수 대한스포츠의학회 1993 대한스포츠의학회지 Vol.11 No.1

The purpose of the study was to investigate the effects of long term physical training on lipid profile in 29 paraglegia. Blood specimens were taken before and after training for 12 weeks group I and the other groups who were control or habitually active, were not trained for 12 weeks Plasma patient(Training Group), 8 control(non-exercise patient) and 12 active paraplegia. The results of tests were summarized as follows : 1. No results changes in the concentration of total cholesterol were observed in all groups. 2. HDL-Cholesterol was increased significantly(27%, p<0.005) in training group, But the change of HDL was not noted in the other group(non-training). 3. C-ratio was decreased in training group(15%) but not significant. 4. Triglyceride was markedly decreased intraining group(39%, p<0.08). Exercise conditioning leading to improved physical fitness in paraplegia may be associated with in increments in HDL-Cholestrol But not associated with total cholesterol.