http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
복강경하 근치적 전립선적출술 후 종양학적 성적과 절제 변연 양성의 위치에 따른 종양학적 성적의 차이: 첨부 절제 변연과 첨부외 절제 변연 양성 간의 비교
하유신,김성인,김수진,조혁진,홍성후,이지열,김준철,김세웅,황태곤 대한비뇨의학회 2009 Investigative and Clinical Urology Vol.50 No.10
Purpose: The aim of this study was to analyze oncologic outcomes based on 7 years of consecutive experience with laparoscopic radical prostatectomy (LRP) and to assess the prognostic difference between an apical positive margin and a non-apical positive margin. Materials and Methods: We reviewed 202 patients who underwent LRP between July 2001 and July 2007 (pathologic stage: T2-T3b, without any adjunctive therapy). Biochemical recurrence (bR) was defined as two consecutive prostate-specific antigen (PSA) values greater than 0.2 ng/ml. We analyzed the differences in bR among the negative margin group (N), the apical positive margin group (A), and the non-apical positive margin group (NA) and factors predicting bR. Results: Overall 3-year probability of bR-free survival (bRFS) was 78% (pT2, 83.7%; pT3, 60.9%). For low-, intermediate-, and high-risk cancer, 3-year bRFS was 94.7%, 82.8%, and 60.7%, respectively. Of the 155 men who had negative and single-site positive margins, the numbers in the N, A, and NA groups were 108, 19, and 28, respectively. bR rates for the N, A, and NA groups were 14.8%, 36.8%, and 46.4%, respectively. Kaplan-Meier curves showed that a positive surgical margin had a significant higher bR compared with the N group; however, the A group experienced a similar bRFS compared with the NA group (p=0.613). Multivariate Cox proportional hazards analysis indicated no significant difference of effect on time to bR between the A and NA groups (hazard ratio=1.213; 95% confidence interval: 0.482-3.052). Conclusions: Our results were almost identical to previous reports of radical prostatectomy in pT2 disease. With increasing experience, we could expect improved oncologic outcomes. In comparison with the NA group, the A group did not show a significant prognostic difference.
하명주,남석우,한종희,윤성필,임태훈,홍성안 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.1
고 에너지, 고 출력 밀도의 이동 전원이 요구되고, 휴대용 전자기기의 연속적 사용이 필요하게 되면서 대용량 배터리를 대신할 대체 연료전지의 수요가 증대됨이 기대되고 있다. 그러나 연료전지를 연속적으로 사용하기 위해서는 에너지 밀도가 높은 연료를 직접사용하거나 연료 개질기가 필요하다. 본 연구에서는 그 중에서 연료개질부분으로 반응 후 배출되는 미반응 수소와 공기의 산화반응에 의한 열을 이용하여 반응열과 기화열이 공급되도록 제작된 마이크로 반응기를 이용하여 메탄올 수증기 개질반응을 수행하였다. 메탄올은 물과 몰비로 1:1.5 (CH3OH:H2O)로 혼합한 수용액을 사용하였으며, 액체 펌프를 통해 기화기로 공급하였다. 기화기 또한 연소반응에서 공급되는 열을 이용하여 기화시켜반응기에 공급하였으며. 반응 후 가스는 GC를 이용하여 분석하였다. 사용된 개질 촉매는 Cu계열의 상용촉매이며, 연소용으로는 세리아로 코팅을 한 니켈판에 Pd, Pt 담지한 촉매를 이용하였다, 반응온도 250~300℃, 공간속도 6,000h-1에서 메탄올 수증기 개질 실험을 수행하였다. 수소 공급 속도에 따른 연소부의 온도 분포와 개질기의 시동 속도 등을 측정했으며. 또한 그에 따른 개질부의 반응변화와 그 성능을 측정하였다.
하유신,김세웅,배웅진,김수진,윤병일,홍성후,이지열,황태곤,황성연,Zhiping Wang 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.1
Purpose: To investigate the effects of anthocyanins extracted from black soybean,which have antioxidant activity, on apoptosis in vitro (in hormone refractoryprostate cancer cells) and on tumor growth in vivo (in athymic nude mouse xenograftmodel). Materials and Methods: The growth and viability of DU-145 cells treated with anthocyanins were assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and apoptosis was assessed by DNA laddering. Immunoblotting was conducted to evaluate differences in the expressions of p53, Bax, Bcl, androgen receptor (AR), and prostate specific antigen(PSA). To study the inhibitory effects of anthocyanins on tumor growth in vivo, DU-145 tumor xenografts were established in athymic nude mice. The anthocyaningroup was treated with daily oral anthocyanin (8 mg/kg) for 14 weeks. After 2 weeks of treatment, DU-145 cells (2×106) were inoculated subcutaneouslyinto the right flank to establish tumor xenografts. Tumor dimensions were measuredtwice a week using calipers and volumes were calculated. Results: Anthocyanintreatment of DU-145 cells resulted in 1) significant increase in apoptosis in a dose-dependent manner, 2) significant decrease in p53 and Bcl-2 expressions (with increased Bax expression), and 3) significant decrease in PSA and AR expressions. In the xenograft model, anthocyanin treatment significantly inhibit tumorgrowth. Conclusion: This study suggests that anthocyanins from black soybeaninhibit the progression of prostate cancer in vitro and in a xenograft model.
홍성효(Sunghyo Hong),하헌주(Hunjoo Ha),김종수(Jongsu Kim) 한국인구학회 2012 한국인구학 Vol.35 No.3
이 연구는 여성가족부의 2009년「다문화가족 실태조사」자료를 이용하여 결혼이주여성의 사회경제적 이혼결정요인을 실증적으로 분석한다. 결혼유지기간을 종속변수로 하는 연속적 생존모형에 대한 회귀분석의 결과에 의하면, 결혼이주여성의 이혼가능성은 중학교 학력에 비해 고등학교 학력을 가지고 있는 경우, 종교단체를 통한 결혼에 비해 가족 또는 친척이 소개했거나 본인 스스로 배우자를 만난 경우, 출산자녀의 수가 보다 많은 경우, 한국으로 이주해 오기 전 취업경험이 있는 경우, 소득이 상대적으로 높은 경우에 상대적으로 낮게 나타난다. 출산자녀가 존재하거나 그 수가 많은 경우에는 그렇지 않은 경우에 비해 이혼의 가능성이 상대적으로 낮아짐을 볼 수 있으며, 이는 다문화가정의 자녀에 대한 지원의 근거가 단순히 이들이 사회적 약자에 해당한다는 점이나 저출산 문제의 해결에만 있지 않고 이들의 이혼가능성을 낮춤으로써 사회적 비용을 줄일 수 있다는 사실에도 존재함을 제시한다. This study empirically analyzes the socioeconomic determinants of divorce of married immigrant women, using 2009 Survey on Multi-culture Families by Ministry of Healthy & Welfare. According to the regression results from the continuous hazard model with the duration of being married as a dependent variable, the likelihood for married immigrant women to divorce appears to be relatively lower when they are high school graduates rather than middle school graduates, their spouses were introduced by their family members or relatives rather than by religious institutes, they met their spouses by themselves compared with the case that religious institutes introduced their spouses, the number of children born by themselves is relatively larger, they have any work experience in their home country before coming to Korea for marriage, or their household incomes are relatively larger. When there exists any child or as the number of children increases, the possibility of marital dissolution seems to relatively be lower. This finding suggests that the arguments of public support for the children from multi-culture families come not only from the fact that in many cases they belong to second-class citizen or the support would be helpful to figure out low fertility problem but also from the fact that the support could reduce social costs by lowering the possibility of marital dissolution of married immigrant women.
A case of delivery of a pregnant woman with COVID-19 infection in Daegu, Korea
배진곤,하진경,권명,박학율,성원준,홍성연 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.6
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),which is affiliated with the β-coronavirus subgroup, which includes SARS-CoV and Middle East respiratory syndromecoronavirus (MERS-CoV), but is far more infectious than the 2. Because it is potentially life-threatening to infantsand pregnant women with weak immune systems, clinical manifestations and vertical transmission of COVID-19 arematters of interest. Staff of the obstetrics department of university hospitals in Daegu and of the Daegu metropolitangovernment designated Daegu Fatima Hospital for the delivery of pregnant women with suspected and confirmedSARS-CoV-2 infection. Thirteen pregnant women with laboratory-confirmed COVID-19 were identified. Among themwas a 28-year-old pregnant woman who had recovered from COVID-19 and had given birth to a healthy girl at 38weeks of gestational age. We present our uncommon experience with a brief review of literatures.