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간울기체(肝鬱氣滯)로 변증시치한 대상포진 후 신경통 환자 치험 2례
최철홍,박선영,고경모,황순이,지선영,정대규,Choi, Cheol-Hong,Park, Sun-Young,Ko, Kyung-Mo,Hwang, Sun-Yi,Jee, Seon-Young,Chung, Dae-Kyoo 대한한방안이비인후피부과학회 2008 한방안이비인후피부과학회지 Vol.21 No.3
Objective : This study report the effect of traditional medical treatment on postherpetic neuralgia(PHN) 2 cases. Methods : We observed 2 PHN cases diagnosed Ganwoolqiche and prescribed herbal medication (Soyosan-Gagambang & Punsimgieum-Gamibang) for each case. Results : Both cases showed efficient clinical results, especially for the pains. Conclution : In this study, operated traditional medical treatment on PHN cases and could find good progress after treatment.
공진단(拱辰丹)과 영신초(靈神草), 원지(遠志), 석창포(石菖蒲) 혼합제제의 기억력과 인지기능 개선 및 항불안에 관한 연구
최철홍 ( Cheol Hong Choi ),김수현 ( Soo Hyun Kim ),정대규 ( Dae Kyoo Chung ) 대한한방신경정신과학회 2011 동의신경정신과학회지 Vol.22 No.2
Objectives: The purpose of this study was to characterize the neuroprotective effects and anxiolytic-like effects of Gongjin-dan and Polygala japonica, Polygala tenuifolia, Acorus gramineusmixed pills(G.J.D-P.P.A.). Methods: The neuroprotective effects of G.J.D-P.P.A. determined by the passive avoidance and Y-maze tasks and Morris water maze task, and the anxiolytic-like effects of the G.J.D-P.P.A. using an elevated plus-maze(EPM) in mice. Results: Drug-induced amnesia was induced by treating animals with scopolamine(1 mg/kg, i.p.). A single G.J.D-P.P.A.(400 and 800 mg/kg) administration significantly enhanced cognitive function and attenuated scopolamine-induced cognitive impairments as determined by the passive avoidance and Y-maze tasks(P < 0.05) and also reduced escape-latency on the Morris water maze task(P < 0.05). The administration of GJD-PPA(400 and 800 mg/kg) significantly increased the percentage of time spent in open arms and entries into the open arms of the EPM compared with saline-treated control group(P < 0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with saline-treated control group. Conclusions: These results suggest that GJD-PPA dramatically possesses the anti-amnestic and cognitive-enhancing activities related to the memory processes, and promotes the anxiolytic-like activity in mice.
자하차(紫河車) 약침(藥鍼)이 ${\beta}A$로 유도(誘導)된 Alzheimer's Disease 병태(病態) 모델에 미치는 영향(影響)
이병훈,박선영,최철홍,이은경,정대규,Lee, Byung-Hun,Park, Sun-Young,Choi, Cheol-Hong,Lee, Eun-Kyung,Chung, Dae-Kyoo 대한한방신경정신과학회 2008 동의신경정신과학회지 Vol.19 No.2
Objective: Hominis Placenta is used in many cure, mainly treats a weak, chronic disease, especially senile. This research investigates the effect of the Hominis Placenta Herbal-Acupuncture Solution on Alzheimer's disease. Method: The effects of the Hominis Placenta Herbal-Acupuncture Solution on (1) $IL-1{\beta}$ protein, $TNF-{\alpha}$ protein, MDA, and CD68/CD11b (2) the behavior (3) the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with 13A were investigated. Results: 1. For the Hominis Placenta Herbal-Acupuncture Solution group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}$ A in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency. 2. The Hominis Placenta Herbal-Acupuncture Solution group suppressed the over-expression of $IL-1{\beta}$ protein, $TNF-{\alpha}$ protein, MDA, and CD68/CD11b, in the mice with Alzheimer's disease induced by ${\beta}A$. 3. The Hominis Placenta Herbal Acupuncture Solution group reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by ${\beta}A$. 4. The Hominis Placenta Herbal-Acupuncture Solution group reduced the Tau protein, GFAP protein, and presenilin1/2 protein, beta-secretase protein, (immunohistochemistry) of hippocampus in the mice with Alzheimer's disease induced by ${\beta}A$. Conclusion: These results suggest that the Hominis Placenta Herbal-Acupuncture Solution group may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the Hominis Placenta Herbal-Acupuncture Solution for Alzheimer's disease is suggested for future research.
칠정상(七情傷)으로 인한 두통 환자의 심박변이도(Heart Rate Variabillity)에 관한 고찰
박선영 ( Sun Yong Park ),최철홍 ( Cheol Hong Choi ),정대규 ( Dae Kyoo Chung ),고경모 ( Kyung Mo Ko ) 대한한방신경정신과학회 2008 동의신경정신과학회지 Vol.19 No.3
Objects : To treat psychogenic headache patients, doctors have to amplify on the headache caused by emotional stress to patients, and assist the patients to cope with difficulties. So, we invesgated HRV of the headache patients caused by Chiljungsang and would like to apply to the clinical treatment. Method : Our study measured time and frequency domain HRV indicies(5-min resting study) of 123 headache patients caused by emotional stress. Standardized tests of HRV allow a quantitative esmation of autonomic nervous system function. Results & Conclusions : 1. The study classed as aspects of the head pain showed the differences in RMS-SD(square root of mean squared difference of successive NN intervals) band, HF(high frequency) band significantly. 2. The male headache patients showed higher all the indicies except heart rate compared to the female patients, significantly in SDNN(standard deviation of NN interval), TP(total Power), HF band. 3. As the patients grow older, SDNN, RMS-SD band was lower and LF(low frequency) band, LF/HF ratio higher significantly. The beginning age lower, SDNN, RMS-SD band was higher significantly. The duration of the disease longer, LF band, LF/ HF ratio was higher significantly.
알콜성 진전섬망으로 진단된 신지부청(神志不淸) 환자 치험 1례
이은경 ( Eun Kyung Lee ),최철홍 ( Chul Hong Choi ),이지인 ( Ji In Lee ),정대규 ( Dae Kyoo Chung ) 대한한방신경정신과학회 2006 동의신경정신과학회지 Vol.17 No.3
Delirium Tremens is the most terrible and dramatic syndrome in Alcohol Withdrawal Syndrome. Delirium Tremens is one of acute psychiatric symptoms and happens that a chronic drinker is suddenly off drinking for any reasons. In Oriental medicine, Alcohol Withdrawal Syndrome is comprised in a category of Jusang(酒傷).In this case, we described a 53-year old man who diagnosed as Delirium tremens. He suffered mental derangement and headache, and his condition was improved through oriental medical treatment.