치매환자와 주 부양자의 관계에 따른 돌봄 부담 요인

최정은(Choi, Jung-Eun),이연화(Lee, Yeon-Hwa) 고령자치매작업치료학회 2021 고령자.치매작업치료학회지 Vol.15 No.2

목적 : 본 연구의 목적은 치매안심센터를 이용하는 주 부양자의 특성별 맞춤형 프로그램과 지원방안을 제시하고자 하며, 치매정책 사업지침 내 가족지원사업의 기초자료를 마련하고자 한다. 연구방법 : 보건소 치매안심센터에 등록된 치매환자의 주 부양자를 대상으로 하였다. 대상자의 일반적 특성 및 우울의 정도와 치매태도, 부양부담, 치매환자의 정신행동증상 여부를 포함한 자가기입 돌봄부담 분석을 활용하여 측정하였다. 측정도구는 각각 Patient Health Questionnaire-9: PHQ-9와 Dementia Attitude Scale: DAS, Short Zarit Burden Inventory: S-ZBI로 평가하였고, 치매환자의 정신행동증상 여부는 Neuropsychiatric Inventory Questionnaire: NPI-Q를 통해 치매환자의 심한정도 및 보호자의 고통정도를 알아보고자 하였다. 또한, 치매안심센터 내 가족지원사업의 서비스 요구도를 5가지 명목척도로 조사 하였다. 연구조사 방법은 우편 및 대면 설문을 통해 진행하였다. 연구 목적에 대한 설명 및 동의를 포함한 설문지를 총 423부를 배부하여 이 중 152부를 회수하였고, 응답에 충실하지 못한 41부를 제외하여 최종 111부룰 대상으로 비교⋅분석하였다. 연구결과 : 치매환자와 주 부양자의 관계에 따른 돌봄부담을 비교한 결과 환자의 정신행동증상여부 (p<.05)에서 배우자 외 집단에서 유의하게 높은 차이를 보였다. 또한, 치매환자의 특성과 부양자의 돌봄 부담에 관한 영향요인을 파악하고자 환자와의 관계를 중심으로 조절 효과를 확인한 결과, 환자의 연령과 부양자 간의 관계가 치매태도에 있어서 상호작용하는 것으로 나타났다. 결론 : 치매안심센터 내 가족지원사업 운영 추진 시 주 부양자의 인구학적 특성 및 환자와의 관계에 따른 맞춤형 프로그램이 요구된다. Objective : The purpose of this study is to collect basic data necessary to propose customized programs and support plans for each characteristic of the Caregiver s who use the Center for dementia. Methods : The subjects were the Caregiver of dementia patients registered at the Center for dementia at the public health center. The general characteristics and depression of the subjects were evaluated as Patient Health Questionnaire-9: PHQ-9, Dementia Attitude Scale: DAS, and the Caregiver’s support burden was evaluated as Short Zarit Burden Inventory: S-ZBI, and whether Behavioral and psychological Symptoms of Dementia Scale (Neuropsychiatric Inventory Questionnaire, NPI-Q) to determine the severity of dementia patients and the degree of pain of caregiver. In addition, a survey was conducted on the service needs of the family support project of the Center for Dementia, The survey was conducted through mail and face-to-face interviews. A total of 423 copies were distributed and 152 of them were recovered, and the final 111 copies were compared and analyzed, excluding 41 copies that were not faithful to the survey. Results : As a result of comparing the burden of care according to the relationship between dementia patients and their caregiver, it was analyzed that there was a significant difference in Behavioral and psychological Symptoms of Dementia (p<.05). In addition, as a result of identifying the characteristics of dementia patients and the factors influencing the care burden of dependents and confirming the moderating effect centering on the relationship with the patient, it was analyzed that there is an interaction according to the patient s age. Conclusion : The Center for dementia needs to organize a program suitable for the characteristics of the caregiver of dementia patients, and for this purpose, the relationship with the patient should be considered.

국내에서 유통 중인 축산환경개선제의 표기사항 및 항생제 내성 현황조사

최정은,이은영,Choi, Jung-Eun,Lee, Eun-Young 한국미생물·생명공학회 2009 한국미생물·생명공학회지 Vol.24 No.3

축산환경개선용 미생물 제품 중 시장점유율을 기준으로 상위제품 A, B,하위 제품 E, F와 현재 개발완료 되어진 C, D를 선정하여 생균수 측정과, 사료첨가용으로 사용이 금지된 항생제에 대한 내성 테스트를 실시하였다. 생균수 측정 결과 상위 점유율의 A, B사 제품은 표기상의 생균수와 일치하였으나, 하위 점유율을 차지하고 있는 E제품의 경우 함유균주나 효능에 대한 정보를 제공하고 않고 있을뿐더러 F사의 제품은 균수가 적게 측정되어 실제 표기사항과 일치하지 않았다. 항생제 내성실험결과 점유율에 따른 상관관계는 없었으나, B사를 제외한 제품의 대부분에서 내성균이 존재함을 확인하였다. Lincosimides 계열의 Lincomycicne과 Clindamycin의 경우 B사를 제외한 제품에서 내성균이 존재하였다. Penicillins 계열의 Amoxicillin, Ampicillin, Penicillin 및 Macrolide 계열의 Erythromycin 항생제는 B사와 E를 제외한 제품에서 내성균이 존재함을 확인하였다. Quinoline계열 Norploxacin 또한 B사와 E사를 제외한 제품에서 내성균을 보였으며 Neomycin의 항생제 또한 유사한 내성분포 결과를 나타내었다. Neomycin과 같은 Aminiglycosides계열의 Gentamycin, Streptomycin은 B사제품을 제외한 제품에서 내성을 나타내었다. 마지막으로 내성-균으로 사용 금지된 Tetracycline계열의 Oxytetracyclin은 12가지 항생제중 가장 높은 비율의 감수성을 나타내었으나 B, E사를 제외한 제품에서 내성균의 존재를 확인하였다. 실험결과 사용 금지된 항생제 품목임에도 불구하고 많은 제품에서 때 성균이 존재하였으며, 이에 따라 환경개선제 특성의 정확한 표기와 체계적인 유통 체계와 검증 과정이 필요하다고 사료된다. A study on livestock environment improving agents was conducted; top two brands (A and B) in the market, bottom two brands (E and F) based on market shares and two newly developed agents (C and D) were measured for viable count and tested for resistance towards antibiotics prohibited against livestock feeds. Test results revealed that the measured viable count of agents A and B matched those on the labels were identical; however agent E lacked information on viable counts nor the intended usage, while the measured viable count of agent F was less than the label-stated count. No correlation was found between the antibiotic-resistance test and market share, and most of the agents excluding B were found to display resistance case of Lincosimides such as Lincomycine and Clindmycin, resistant bacteria were found, with the except of agent B. Amoxicillin, Ampicillin and Penillin (type-Penecillins) and Erythromycin (type-Macrolide) were shown to contain resistant bacteria, with the except of agents Band E; the same for Norploxacin (type-Quinoline) and Neomycin antibiotics. Aminoglycosides such as Gentamycin and Streptomycin contained resistant bacteria, excluding agent B. Oxytetracyclin (type-Tetracycline), which is banned for use as resistant bacteria showed the highest sensitivity among the 12 antibiotics, revealed positive results in the test for resistant bacteria; again excluding of agents Band E. These results reveal that many agents contained resistant bacteria despite the fact that they were prohibited; this calls for a more accurate display of the facts and specifications, systematic distributions and strict verification processes of environment improving agents.

제왕절개 환자에서 적극적 가온 요법의 효과

최정은(Choi, Jung Eun),김미선(Kim, Mee Sun),송진란(Song, Jin Ran) 기본간호학회 2017 기본간호학회지 Vol.24 No.3

Purpose: The aim of this study was to synthesize the best available evidence for active warming interventions during cesarean section. Methods: A database search was done for randomized controlled trials utilizing active warming interventions. Maternal temperature, shivering and neonatal temperature were evaluated as outcome variables. Data were analyzed using Cochrane Review Manager software Version 5.3. Results: Thirteen studies including 1306 patients were reviewed. The degree of lowering of maternal temperature decreased in the warmed fluids (MD 0.51; p=.004) and warming mattress interventions (MD 0.22; p<.001) compared with control groups. Incidence of shivering was also lower in the active warming group (OR 0.55; p=.003). There was no statistically significant difference in maternal temperature with a forced air warming intervention (MD 0.64; p=.15) or in neonatal temperature (MD 0.12; p=.26). Conclusion: Findings show that with warmed fluids and warming mattresses applied during cesarean sections maternal temperature decline was reduced and also the incidence of shivering declined, but no significant effect was observed for forced air warming interventions. These findings provide a basis for developing a warming guideline for women having a cesarean section and will help to improve the quality of care for cesarean section patients.

성인 천식 환자에서 체질량지수와 기도과민성 및 폐기능의 연관성

최정은 ( Jung Eun Choi ),신태림 ( Tae Rim Shin ),박상면 ( Sang Myeon Park ),김주희 ( Joo Hee Kim ),신성호 ( Sung Ho Shin ),이현영 ( Hyun Young Lee ),장주아 ( Juah Jang ),이훈구 ( Hun Gu Lee ),김철홍 ( Cheol Hong Kim ),현인규 ( In 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1

Purpose: Obesity is commonly regarded as a risk factor for asthma development, poor asthma control, and poor response to asthma therapy. However, its relationships are not always consistent. Gender difference has been reported to influence asthma severity and asthma control. We investigated the contribution of obesity to airway hyperresponsiveness (AHR) and lung function before and after treatment in adult asthmatics. Methods: The medical records of a total of 323 adult asthmatics were analyzed retrospectively. Asthma was diagnosed based on the positive result of methacholine bronchial provocation test (PC20≤25 mg/mL) or bronchodilator test (≥12% and 200-mL improvement in forced expiratory volume in 1 second after inhalation of a bronchodilator). Follow-up spirometry was performed in 113 patients after at least 3 months of asthma treatment with controller medication. Percent change between spirometry before and after treatment was defined as {[(value after treatment.value before treatment)/value before treatment]×100}. Body mass index (BMI, weight [kg]/height [m2]) was categorized into underweight (<18.5), normal weight (18.5.24.9), overweight (25.0.29.9), and obese (>30) according to the world health organization classification. Results: BMI did not show any significant correlation with PC20 value of methacholine provocation test and each lung function parameter before and after treatment. When we divided the study subjects according to gender and age, BMI was negatively correlated with PC20 value only in female adult asthmatics under 65 years old (r=.0.024, P=0.036). Conclusion: Obesity is positively correlated with the intensity of AHR in female adult asthmatics. Gender seems to differentially contribute to the relationship between BMI and AHR. (Allergy Asthma Respir Dis 2014;2:16-22)

식품 및 환경 기타 국내에서 유통 중인 축산환경개선제의 표기사항 및 항생제 내성 현황조사

최정은 ( Jung Eun Choi ),이은영 ( Eun Young Lee ) 한국미생물생명공학회 2009 한국미생물·생명공학회지 Vol.37 No.3

불멸화된 일차 간세포를 이용한 C형 간염바이러스의 in vitro 배양

최정은 ( Jung Eun Choi ),허원희 ( Won Hee Hur ),신주엽 ( Ju Yeop Shin ),박련숙 ( Lian Shu Piao ),윤승규 ( Seung Kew Yoon ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.3

Background/Aims: It is essential to develop an in vitro culture model of primary hepatocytes for the study of hepatocellular function and the pathogenesis of hepatitis C virus (HCV) infection. In this study, we have established the immortalized primary human hepatocyte (IPHH) and performed in vitro culture of HCV derived from human patient. Methods: Primary human hepatocytes were isolated from surgically resected liver tissue and then were immortalized by transfection with the SV40 large T antigen. The characterization of the IPHH during culture was analyzed by immunocytochemistry, RT-PCR, Western blot, ELISA, and soft agar assay. Next, sera and/or liver tissue homogenates from surgically resected liver tissues of patients with HCV infection were inoculated for the culture of HCV in IPHH. After HCV RNA extraction from IPHH and culture media, positive or negative stranded HCV RNA was examined by specific nest RT-PCR. Results: IPHH expressed liver-associated proteins but did not express alpha-fetoprotein. Also IPHH showed ammonia removal activity. With regard to its malignant potential, colony formation in soft agar assay was not observed. Next, positive and negative stranded HCV RNAs in IPHH infected with patient`s sera plus liver tissue homogenates were clearly detected whereas those in IPHH infected with only patient`s sera were not detected. Conclusions: These results demonstrated the phenotypic characteristics of IPHH and the feasibility in vitro culture system of HCV infected human samples. This system might be useful for study of pathogenesis of HCV infection or hepatocyte-based applications. (Korean J Gastroenterol 2008;52:150-160)

부 · 모의 양육행동과 유아의 외현화 문제행동의 관계에서 정서조절능력의 매개효과

최정은(Jung Eun Choi),이소연(SoYean Lee) 한국아동학회 2017 아동학회지 Vol.38 No.1

Objective: The purpose of this study was to investigate the mediating effects of emotional regulation abilities on the relationship between parenting behavior and preschoolers’ externalizing behavior problems. Methods: A survey was conducted with the parents of 166 preschoolers; the children were attending seven different daycare centers in Seoul. Results: The results were as follows: First, emotional regulation abilities fully mediated the relationship between fathers’ rejection-restriction parenting behavior and externalizing behavior problems. Second, emotional regulation abilities fully mediated the relationship between mothers’ warmth-acceptance, rejection-restriction, and permissive-neglectful parenting behavior and externalizing behavior problems. Third, after controlling for fathers’ parenting behavior, emotional regulation abilities fully mediated the relationship between mothers’ parenting behavior and externalizing behavior problems. Conclusion: Both parenting behavior and emotional regulation abilities should be considered when attempting to understand the development of preschoolers’ externalizing behavior problems. In particular, the results from this study stress the important role of emotional regulation abilities in decreasing externalizing behavior problems and buffering against the influence of negative parenting behavior.

IoT 오픈 플랫폼 암호기술 현황 및 보안 요구사항 분석

최정인,오윤석,김도원,최은영,서승현,Choi, Jung-In,Oh, Yoon-Seok,Kim, Do-won,Choi, Eun Young,Seo, Seung-Hyun 한국정보처리학회 2018 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.7 No.7

IoT 기술의 급격한 발전으로 스마트홈이나 스마트 시티와 같은 다양한 편리한 서비스들이 실현되었다. 그러나 무인 환경에서의 IoT 기기는 도청 및 데이터 위조, 무단 액세스로 인한 정보 누출 등 다양한 보안 위협에 노출되어 있다. 안전한 IoT 환경을 구축하려면 IoT 기기에 적절한 암호화 기술을 사용해야 한다. 그러나 IoT 기기의 제한된 자원으로 인해 기존 IT 환경에 적용된 암호화 기술을 그대로 적용하는 것은 불가능하다. 본 논문에서는 성능에 따라 IoT 디바이스의 분류를 조사하고 IoT 디바이스의 보안 요구 사항을 분석한다. 또한 AllJoyn, oneM2M, IoTivity와 같은 IoT 개방형 표준 플랫폼의 현재 암호화 기술의 사용 현황을 조사하고 분석한다. 암호화 기술 사용 현황에 대한 연구를 기반으로 각 플랫폼이 보안 요구사항을 만족하는지 확인한다. 각 IoT 개방형 플랫폼은 기밀성, 무결성, 인증 및 인증과 같은 보안 서비스를 지원하기위한 암호화 기술을 제공한다. 하지만 혈압 모니터링 센서와 같은 자원이 제한된 IoT 장치는 기존의 암호화 기법을 적용하기가 어렵다. 따라서 무인 환경에서 전력 제한 및 자원 제약을 받는 IoT 장치에 대한 암호화 기술을 연구 할 필요가 있다. With the rapid development of IoT(Internet of Things) technology, various convenient services such as smart home and smart city have been realized. However, IoT devices in unmanned environments are exposed to various security threats including eavesdropping and data forgery, information leakage due to unauthorized access. To build a secure IoT environment, it is necessary to use proper cryptographic technologies to IoT devices. But, it is impossible to apply the technologies applied in the existing IT environment, due to the limited resources of the IoT devices. In this paper, we survey the classification of IoT devices according to the performance and analyze the security requirements for IoT devices. Also we survey and analyze the use of cryptographic technologies in the current status of IoT open standard platform such as AllJoyn, oneM2M, IoTivity. Based on the research of cryptographic usage, we examine whether each platform satisfies security requirements. Each IoT open platform provides cryptographic technology for supporting security services such as confidentiality, integrity, authentication an authorization. However, resource constrained IoT devices such as blood pressure monitoring sensors are difficult to apply existing cryptographic techniques. Thus, it is necessary to study cryptographic technologies for power-limited and resource constrained IoT devices in unattended environments.

역사물『요시쓰네(義經)』의 장르별 표현양상의 비교고찰 : 오슈 도피(奥州落ち) 일화를 중심으로

최정은(崔廷銀)(Choi, Jung-Eun),최중락(崔中洛)(Choi, Joong-Rak) 일본어문학회 2012 일본어문학 Vol.56 No.-

한양방치료를 병행 후 호전된 진성적혈구증가증 환자 1례

최정은,조종관,이연월,유화승,Choi, Jung-Eun,Cho, Chong-Kwan,Lee, Yeon-Weol,Yoo, Hwa-Seung 대한암한의학회 2010 大韓癌韓醫學會誌 Vol.15 No.1

Objective: This study reports one case of polycythemia vera patient treated with oriental medicine in conjunction with conventional medicine. Methods: One patient who was diagnosed with polycythemia vera was treated using different modalities of herbs, acupuncture, and pharmacopuncture. An herbal formula, Yongdamsagan-tang was given three times a day with daily acupuncture treatment session, in addition to Soyeom and Jahageo pharmacopuncture injection which were administered three times a week. After treatment, patient's symptoms and blood test results were observed and analyzed. Results: After ten days of treatment, the patient had shown improvements in symptoms of headache, dizziness, tinnitus, and itchiness. Two months later, laboratory findings continued to be kept within the normal range and the intervals of phlebotomy therapy has extended to three months. Conclusions: This case study shows minimum evidence of safety and efficacy of oriental medicine for managing symptoms of polycythemia vera. Considering this is only a short term, single case study, further research is needed to confirm these results.