현토고본환이 노화유발 백서의 항산화능에 미치는 영향

최우석,강석봉,Choi, Woo-Suk,Kang, Seok-Bong 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4

Objectives : This experiment was done to evaluate the effects of Hyuntogobon-hwan(HTG) on antioxidant capability and lipidic concentration in blood, both of which are presumed to be related to aging. Methods : 12 week-old SD rats were divided into controlled group, uncontrolled group and HTG group. As controlled and HTG groups were given subcutaneous injection of D-galactose(50mg/kg/rat), at the same time HTG group was administered extract of Hyuntogobon-hwan(270mg/200g). HTG injections continued for 6 weeks. After initial injections, blood was drawn from each group and the following were measured: the activity of SOD, GSH-px, catalase in erythrocytes, TSARS value, concentration of total lipid, tryglyceride in blood plasma. Results : The activities of SOD and GSH-px in erythrocytes increased significantly in HTG group compared with controlled group. The activity of catalase seemed to increase slightly, but it was barely noticeable. The concentration of total lipid in plasma decreased significantly in HTG group compared with controlled group. The value of TBARS in plasma seemed to decrease slightly, but it was barely noticeable. Conclusions : According to the above results, Hyuntogobon-hwan has an influence on aging by virtue of activation of antioxidative enzyme systems in erythrocytes and concentrations of lipid in blood plasma.

대보음환(大補陰丸)이 Streptozotocin으로 유도된 백서(白鼠)의 당뇨병 및 당뇨병 합병증에 미치는 영향

최우석,윤경민,이연경,강석봉,Choi, Woo-Suk,Yoon, Kyeong-Min,Lee, Yeon-Kyeong,Kang, Seok-Bong 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.4

Objectives : The object of this study was to investigate the effects of Daeboeum-hwan (DBEH) aqueous extracts on Streptozotocin (STZ)-induced rat diabetes and related complications. Methods : SD rats were divided into 6 groups (n =8) : 50 mM citrate buffer and vehicle (distilled water 5 ml/kg) administered group (Intact control), STZ treatment (60 mg/kg, single intraperitoneally administered) and vehicle administered group (STZ control), STZ treatment and silymarin 100 mg/kg administered group (Reference), and STZ treatment and DBEH extracts 50, 100 and 200 mg/kg administered groups. DBEH extracts were orally administered once a day for 28 days from 3 weeks after STZ treatment. The results were compared with silymarin 100 mg/kg. Results : Decreases in the body weights, increase of kidney and liver weights, blood glucose, BUN, creatinine, AST, ALT, LDL, triglyceride and total cholesterol levels with decreases of HD L levels, increases of pancreatic MDA contents and decreases of GSH contents were detected in STZ control as compared with intact control. These diabetes and related complications were inhibited by treatment with 100 and 200 mg/kg of DBEH extracts. Conclusion : DBEH extracts showed favorable effects on STZ-induced diabetes and related complications mediated by their antioxidant effects as similar to silymarin. Because the lowest dosage (50 mg/kg) of DBEH treated group did not show any favorable effects as compared with STZ control, the effective dosages of DBEH is considered as about 100 mg/kg, while DBEH extracts at 200 mg/kg showed similar effects as compared with 100 mg/kg of silymarin. It, therefore, is expected that DBEH will show favorable effects on diabetes and various diabetic complications.

뇌동맥확장증에 대한 전산화단층촬영소견

최우석,고영태,임재훈,이선화,윤엽,이동호,임언,이봉암,김국기,김광명,김태성,Choi, Woo-Suk,Ko, Young-Tae,Lim, Jae-Hoon,Lee, Sun-Wha,Yoon, Yup,Lee, Dong-Ho,Leem, Won,Rhee, Bong-Arm,Kim, Gook-Ki,Kim, Kwang-Myung,Kim, Tae-Sung 대한영상의학회 1987 대한영상의학회지 Vol.23 No.1

The computed tomographic findings of cerebral arterial ectasia in 8 patients, of which 5 cases were angiographically documented, are reported. The ectatic arteries, located predominantly in the suprasellar and interpeduncular cisterns, appeared as serpiginous, tubular structures on the unenhanced scan. The enhanced CT scan demonstrated dense, sharply defined, homogeneous intraluminal enhancement. Until recently, the diagnosis of cerebral arterial ectasia was usually established by angiography. With introduction of CT it has become possible to noninvasively indentify and characterize this vascular disorder and its associated intracranial complications. The vertebrobasilar dolichoectasia may be diagnosed by CT as an extra-axial lesioin in the cerebellopontione angle. It enhances in a tubular fashion after intravenous injection of contrast.

Neuroimaging of Traumatic Brain Injury

최우석,Choi, Woo Suk The Korean Society of Biological Psychiatry 1995 생물정신의학 Vol.2 No.2

두부 외상은 많은 발생율과 사망율을 차지하고 있으며, 건강한 생활을 위해 큰 관심을 갖게 되었다. 신경방사선영상은 외상성 뇌손상 환자들의 진단과 치료에 필수적인 방법이다. 뇌손상의 기본 기전, 병리, 그리고 영상 소견을 이해 하는 것은 매우 중요하다. 1970년대에 Glasgow coma scale의 형상과 전산화단층촬영(CT)의 발달은 임상의사들이 두부외상에 대한 평가와 환자들의 경과를 예상하는데 극적인 변화를 주었다. 최근 자기공명영상(MRI)의 발달로 외상성 뇌손상의 형태를 더욱 이해 하게 되었고, 두부 외상의 발견율이 높아지게 되었다.

인쇄용 페이스트의 조성변화가 탄소나노튜브 캐소드의 전계방출 특성에 미치는 영향

최우석,신허영,김동희,안병건,정원섭,이동구,조영래,Choi, Woo-Suk,Shin, Heo-Young,Kim, Dong-Hee,Ahn, Byung-Gun,Chung, Won-Sub,Lee, Dong-Gu,Cho, Young-Rea 한국재료학회 2003 한국재료학회지 Vol.13 No.10

The effects of paste materials on field emission properties in a carbon nanotube(CNT) cathode were investigated for high-efficient field emission displays. The major components in CNT paste for screen printing were a metallic Ag-paste, a dielectric glass-frit and CNT ink. The emission current from the cathode by an electron tunneling effect increased with an increase in the dielectric material fraction in the CNT paste, which is related to an increase of field enhancement factor in Fowler-Nordheim equation. The surface treatment used, after soft baking of the screen-printed CNT films, greatly affected the decrease in the turn-on field in CNT cathode and the uniformity of emission sites over the entire CNT film area.

「懷思」篇으로 바라본 이백의 그리움

최우석(Choi, Woo-suk)(崔宇錫) 대한중국학회 2019 중국학 Vol.69 No.-

The number of poems was not much, because the 「Huaisi(懷思)」 of LI Bai contained a total of 11 poems, but it was expected that this analysis would help to understand the deep inner world of LI Bai more deeply. The nickname 「Huaisi」 might be “a longing or thinking”. In the cigar in LI Bai‘s 「Huaisi」, I could get a glimpse of the following three longings or thoughts. The first was the longing for ‘Yinyi’ or ‘Youxian’, which accounted for the largest portion of the total 11 numbers, and the second was the longing for the dead. Third, the longing for friends. However, this content is in line with the so-called 「Huaisi Fu(懷思賦)」 of the north and south of Weijin, so this study also used it as a source ofLI Bai‘s 「Huaisi」. On the other hand, in the 「Huaisi」 section of LI Bai, it was found that it was composed of contents that directly miss certain specific objects or miss the things related to them. Specifically, ‘Dongsan’ as a specific space of ‘Yinyi’ which is often mentioned in poetry was a description of the shape of ‘XIE An(謝安)’, and ‘HE Zhizhang(賀知章)’ and ‘CUI Zhongzhi(崔宗之)’ appeared as objects that LI Bai directly missed. LI Bai s 「huaisi」 was a song of longing for the object that exists very specially in the inner world of LI Bai. It was no coincidence that these three people were introduced side by side in the “preface” of the house of the second house written by Lee Yang-bing, and that the anecdote was introduced in a specific way. 이백의 「회사」편에는 다음의 세 가지 정도의 ‘그리움’이 드러나 있다. 첫째는 은일이나 유선에 대한 그리움이었고, 둘째는 망자에 대한 그리움이었으며, 셋째는 친구에 대한 그리움이었다. 그런데 이러한 내용은 위진남북조의 이른바 ‘회사부(懷思賦)’의 내용과 상당 부분 일치하는 것이어서, 본고에서는 이것으로써 이백 「회사」편의 연원으로 삼았다. 특히 이러한 내용에는 사안, 하지장 그리고 최종지가 그 그리움의 주요 대상이었다. 사실 사안은 이백에게 있어서 시공간을 초월해 이백이 먼저 다가간 전대(前代)의 ‘지음’이었고, 하지장은 자신을 먼저 알아봐 준 당대(當代)의 ‘지음’이었으며, 최종지는 가장 격의 없이 지낼 수 있었던 현실 속의 ‘지음’이었던 것으로 파악된다. 이백의 「회사」편은 바로 이렇듯 이백의 내면세계 속에 매우 각별하게 존재하는 대상에 대한 그리움의 노래였던 것이다.

당대(唐代) 시격론(詩格論)과 선(禪)

최우석 ( Woo Suk Choi ) 中國語文硏究會 2005 中國語文論叢 Vol.0 No.28

평균회귀 또는 모멘텀 매매? VKOSPI 사례 연구

최우석 ( Woo Suk Choi ),김성호 ( Sung Ho Kim ),최강석 ( Kang Suk Choe ),조정근 ( Joung Keun Cho ) 아시아.유럽미래학회 2016 유라시아연구 Vol.13 No.1

대한민국 주식시장의 대표적인 대형주 지수인 코스피 200지수와 추정모델에 기반하지 않은 내재변동성지수인 VKOSPI 변동성지수 분석을 통해 대형주 주가지수와 내재변동성지수간 통계적으로 유의한 부(負)의 관계를 확인하였다. 본 연구는 VKOSPI 변동성지수의 비대칭적 정보성격의 존재하에서 의미있는 정보지수로서의 VKOSPI 변동성 지수를 활용한 알고리즘 트레이딩 전략을 개발하는데 주안점을 두었다. VKOSPI지수의 변동에 따른 코스피200 주가지수선물의 Long 및 Short 매매전략은 본 연구에서 개발된 알고리즘 트레이딩 플랫폼을 통하여 외표본 시뮬레이션에 적용되었다. 이를 통해 큰 규모의 VKOSPI지수변동은 특히 위험회피도 상승국면에서 양(陽)의 주가지수대비 초과수익률을 실현할 기회에 대한 경험적 증거를 확인할 수 있었다. 이어 VKOSPI지수의 각각의 매매신호 효율성에 대한 평가를 통해 위험선호도의 하락, 상승 및 정체기간을 포괄하여 주가지수 벤치마크 성과를 초과할 수 있는 알고리즘매매의 플랫폼을 개발하는 연구가 수행되었다. 본 연구는 (1) 2003년부터 2007년말까지를 위험회피도 하락 및 양(陽)의 주가지수수익률 국면, (2)2008년부터 2011년말까지를 위험회피도 상승 및 지수수익률 변동성 확대국면 및 (3) 2012년부터 본 연구데이터의 마지막 기간인 2015년 5월29일 (영업일 기준)까지 미미한 주가지수수익률을 기록한 위험회피도 조정국면으로 연구 대상 기간을 대 분류한 후, VKOSPI지수 분석을 통하여 위험회피도 국면별 비대칭성분석 및 고유의 알고리즘매매 플랫폼을 통한 동적자산배분 전략을 수행하였다. 그리하여 변동성지수를 통해 추출된 매매신호를 바탕으로 한국 주식시장의 변동성지표의 지수수익률간 비대칭성에 기반한 주가지수 벤치마크 수익률을 초과하는 주가지수선물 매매전략은 지수변동성 상승국면에서 가장 효율적인 것으로 평가되었다. 본 연구에서 규명된 결과로 Copeland and Copeland (1999)에서 제안된 초단기 이상 (異常)수익현상이 충분히 확인되지 못하였으며 VKOSPI지수에 내재된 시장 타이밍 관련 정보는 초단타매매 또는 데이트레이더들 보다는 최장 9개월 가량의 투자기간을 가진 투자자에게 보다 지속 가능한 매매신호로서 적절한 것으로 판단된다. For the KOSPI200 Index (“Index”), a well-known negative and statistically significant relationship exists between the returns of the Index and VKOSPI, the official model-free implied volatility index. Our primary research purpose is to test VKOSPI as an informative and meaningful trading indicator and to develop a set of algorithmic trading strategies to time the market. The trading strategies are evaluated in terms of their ability to develop an algorithmic trading platform that will outperform the index benchmark in falling, rising and steady risk aversion regimes. There is some empirical evidence for expecting opportunities for positive future excess returns for long and short positions triggered by large changes in the VKOSPI. This finding is more prominent during the periods of both rising and steady risk aversions. Trading strategy in this research is tested on the data period from Jan 2, 2003 to May 29, 2015, using an out-of-sample algorithmic trading platform. We reorganized the data sample into 3 sub-periods: (1) Falling Risk-Aversion Regime: From January 2, 2003 to December 28, 2007 of pre-global financial crisis period of a declining VKOSPI, a positive market return and relatively small VKOSPI fluctuations (P1). (2) Rising Risk-Aversion Regime: From January 2, 2008 to December 29, 2011 as the period of elevated VKOSPI and market stress (P2). (3) Steady risk-Aversion Regime: From January 2, 2012 to May 29, 2015 a very low, consistent VKOSPI with mediocre market returns, especially in Korean equities (P3). The time-varying return-volatility relation is used to implement a set of dynamic asset allocation strategies by analyzing VKOSPI with its corresponding Index. With asymmetric volatility phenomenon in the Korean stock market, our benchmark-outperforming dynamic asset allocation strategies are effectively developed by processing meaningful signals from VKOSPI on the Index Futures. Empirical evidence here was not sufficient enough to confirm the short-term profit anomaly suggested by Copeland and Copeland (1999) that the information content in VKOSPI was not for short-term or day traders. It was rather more sustainable for those for up to 9 months’ of investment horizons.

한대(漢代) 정교론(政敎論)과 시가(詩歌) 속의 정치적 색채 연구

최우석 ( Woo Suk Choi ) 中國語文硏究會 2009 中國語文論叢 Vol.0 No.42

논문(論文) : 이백(李白)의 < 행역(行役) >시(詩) 초탐(初探)

최우석 ( Woo Suk Choi ) 고려대학교 중국학연구소 2015 中國學論叢 Vol.50 No.-

This paper analyzes the poetry of “XingYi” by Li Bai and studies the characteristics of expressions in it. First, this poetry mainly includes appreciating scenary, longing for friends, the yearning for Yinyl, and other things. The majority of appreciating scenary is composed of depicting natural scenary in motion. The author Li Bai also describes the longing for his home town and friends. Furthermore, The yearning for Yinyl incorporates the desire to live with Taoist hermits in remote forests. In the remaining parts, he expresses his sorrows for not being able to fulfill his will and longing for the Palace. The poetry of XingYi was influenced by Xiaotong’s Wenxuan in its content and format. In addition, the author describes the speed of moving quite fastly in joyful feelings and depicts it quite slowly in adverse or sad feelings. Finally, the author utilized hyperbole, simile, and abundant imagination which renders this poetry masterfully romantic.